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    • 3. 发明公开
    • SMALL ANIMAL ANESTHETIZATION GAS MASK WITH INTEGRATED VALVE FUNCTION
    • EP4215157A1
    • 2023-07-26
    • EP22153270.8
    • 2022-01-25
    • Bruker Belgium N.V.
    • Claessens, Timothy
    • A61D7/04A61M16/06
    • An anesthetization gas mask (10) for a small animal (A) comprising a first mask part (11) providing an inlet (I) for an anesthetization gas (G), a second mask part (12) for transmitting the anesthetization gas being mechanically connected to the first mask part, wherein the first and the second mask part at least partially define an anesthetization volume (V) for receiving a mouth part of the small animal is characterized in that the second mask part for transmitting the anesthetization gas is movably connected to the first mask part having the inlet for an anesthetization gas, and that the anesthetization gas mask is geometrically constructed and configured such that a movement of the first mask part from a working position to a blocking position relative to the second mask part blocks the passage of anesthetization gas into the anesthetization volume. This anesthetization gas mask has a valve function integrated in the mask system itself, so that anesthesia gas is not spilled when not in use and with a fixed geometry so that the extraction is always present when handled. The new mask system is easy to use, in particular for rats or mice, and can easily be applied in a wide variety of locations through it is small and compact construction.
    • 9. 发明公开
    • EXPOSURE SYSTEM
    • EXPOSITIONSSYSTEM
    • EP2173419A4
    • 2016-07-27
    • EP08767254
    • 2008-06-27
    • INHALATION SCIENCES SWEDEN AB
    • GERDE PER
    • A61M15/00A61B5/08A61D7/04A61M11/06A61M16/10B05B7/00G01N33/497
    • A61D7/04A61B5/0813A61B5/087A61B5/097A61B2503/40A61M15/00
    • A system and a method for studying or predicting the interaction between a lung and an aerosolized agent. The system comprises an aerosol generator (10) sealingly connected to an exposure arrangement adapted to provide a transport aerosol flow from an aerosol holding chamber of the aerosol generator (10) to a flow junction; and an exposure aerosol flow from the flow junction for distribution to an exposure organ with breathing capacity thereby a providing a residual aerosol flow transported away from the flow junction. The exposure arrangement further comprises a flow rate monitoring device located upstream the flow junction for monitoring the transport aerosol flow, a device for measuring the aerosol particle concentration located downstream the flow rate monitoring device, and optionally a flow control function for controlling the transport aerosol flow. Using the system for predicting the interaction between a lung and an aerosolized agent minimizes the loss of the agent.
    • 用于研究或预测肺和雾化剂之间的相互作用的系统和方法。 该系统包括密封地连接到曝光装置的气溶胶发生器(10),该曝光装置适于提供从气溶胶发生器(10)的气溶胶容纳室到流动接头的运输气溶胶流; 以及来自流动接合点的暴露气溶胶流,以分配到具有呼吸能力的曝光器官,从而提供从流动接合点输送的残留气溶胶流。 曝光装置还包括位于流动接头上游的用于监测运输气溶胶流的流量监测装置,用于测量位于流速监测装置下游的气溶胶颗粒浓度的装置,以及可选地用于控制运输气溶胶流的流量控制功能 。 使用该系统来预测肺和雾化剂之间的相互作用使药剂的损失最小化。