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1. 发明授权

EP1940249B1 NOVEL FORMULATIONS OF FAT-SOLUBLE ACTIVE INGREDIENTS WITH HIGH BIOAVAILABILITY 有权
标题翻译： UE IT IT IT IT IT IT IT IT IT IT IT IT IT IT IT IT IT IT IT IT IT IT IT IT IT IT
公开(公告)号：EP1940249B1
公开(公告)日：2015-06-03
申请号：EP06806421.1
申请日：2006-10-20
申请人： DSM IP Assets B.V.
发明人： BECK, Markus , GRASS, Hansjoerg , LEUENBERGER, Bruno, H. , NOWOTNY, Markus , SCHAEFER, Christian , VOELKER, Karl, Manfred
IPC分类号： A23L1/30 , A23L1/29 , A23L1/303 , A23L1/275 , A23K1/16 , A61K8/00
CPC分类号： A61K9/2081 , A23K20/174 , A23K20/179 , A23L5/44 , A23L33/155 , A23V2002/00 , A61K8/0241 , A61K8/31 , A61K9/2013 , A61K9/2018 , A61K9/2059 , A61K31/01 , A61K31/047 , A61K2800/52 , A61K2800/56 , A61Q19/00
摘要： The present invention relates to formulations of a pharmacological effective fat-soluble active ingredient with a high bioavailability of said fat-soluble active ingredient as well as to their manufacture and use as dietary supplement, food, feed, personal care product and/or pharmaceutical. Such formulations are those which when dissolved, dispersed or diluted in/with water have an extinction E 1/1 at a wavelength in the range of from 200 to 800 nm, preferably in the range of from 250 to 600 nm, more preferably in the range of from 250 to 500 nm, more preferably in the range of from 370 to 485 nm, of >=380, preferably of >=600, most preferably >=900. In preferred embodiments of the formulations of the present invention such formulations show an extrusion loss of fat-soluble active ingredient of
摘要翻译：本发明涉及具有所述脂溶性活性成分的高生物利用度的药理学有效的脂溶性活性成分以及作为膳食补充剂，食品，饲料，个人护理产品和/或药物的制造和用途的制剂。这样的配方是当在水中溶解，分散或稀释时在200至800nm范围内，优选在250至600nm范围内的波长具有消光E 1/1，更优选在范围为250〜500nm，更优选为370〜485nm，≥380，优选为≥600，最优选为900。在本发明制剂的优选实施方案中，这些制剂显示当压制成片剂时，脂溶性活性成分的挤出损失≤30％。

2. 发明授权

EP2222193B1 CALCIUM-FORTIFIED BEVERAGES AND METHOD OF MAKING THEREOF 有权
标题翻译：与钙OFFSET用于生产饮料和过程
公开(公告)号：EP2222193B1
公开(公告)日：2015-02-18
申请号：EP08866988.2
申请日：2008-12-09
申请人： TROPICANA PRODUCTS, INC.
发明人： RIVERA, Teodoro , SHIELDS, Nicholas , DOUGLASS-MICKEY, Jason
IPC分类号： A23L1/303 , A23L1/304 , A23L2/00 , A23L2/02 , A23L2/52
CPC分类号： A23L2/02 , A23L2/52 , A23L33/155 , A23L33/16 , A23V2002/00

3. 发明授权

EP2337461B1 METHOD TO VITAMIN-D ENRICH FOOD USING YEAST AND UV LIGHT 有权
标题翻译：工艺为食维生素D使用酵母和紫外线富集
公开(公告)号：EP2337461B1
公开(公告)日：2015-01-28
申请号：EP09808463.5
申请日：2009-08-20
申请人： Viasolde AB
发明人： EKLUND-JONSSON, Charlotte , JOHANSSON, Sara , HJORTMO, Sofia , LINDQVIST, Helen
IPC分类号： A23L1/303 , A23L1/28
CPC分类号： A23L33/155 , A23L33/14

4. 发明授权

EP2629626B1 FOOD PRODUCT CONTAINING ETHYLCELLULOSE 有权
标题翻译：乙基纤维素食物产品
公开(公告)号：EP2629626B1
公开(公告)日：2014-11-12
申请号：EP11760499.1
申请日：2011-09-26
申请人： Unilever N.V. , Unilever PLC, a company registered in England and Wales under company no. 41424
发明人： BOT, Arjen , WIERINGA, Jan, Alders
IPC分类号： A23D7/005 , A23L1/01 , A23L1/0534 , A23L1/30 , A23L1/303 , A23L1/035
CPC分类号： A23D7/005 , A23D7/0053 , A23D7/0056 , A23L5/12 , A23L29/10 , A23L29/262 , A23L33/115 , A23L33/155 , A23V2002/00 , A23V2250/5108

5. 发明授权

EP1728507B2 USE OF VITAMIN K FOR REVERSING CALCIFICATION OF BLOOD VESSELS 有权转让
标题翻译：组合物可用于治疗和预防心血管疾病
公开(公告)号：EP1728507B2
公开(公告)日：2014-11-12
申请号：EP06076172.3
申请日：2006-06-06
申请人： NattoPharma ASA
发明人： Vermeer, Cees
IPC分类号： A61K31/122 , A61K31/593 , A23L1/302 , A23L1/303 , A61P9/10
CPC分类号： A61K31/593 , A23L33/15 , A23L33/155 , A23V2002/00 , A61K31/122 , A61K2300/00 , A23V2250/71 , A23V2200/326

7. 发明公开

EP2712928A1 METHOD FOR PRODUCING NATURAL -CAROTENE BY FERMENTATION AND USE THEREOF 有权
标题翻译：用于生产天然β-胡萝卜素对发酵和应用方法
公开(公告)号：EP2712928A1
公开(公告)日：2014-04-02
申请号：EP12789051.5
申请日：2012-05-15
申请人： Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory
发明人： XU, Xinde , JIAO, Mingqing , SHAO, Dong , SHAO, Bin , YU, Leiming
IPC分类号： C12P23/00 , A23L1/303 , A61K31/07 , A61K8/67 , A61P3/02 , C07C403/24 , C12N1/14 , C12R1/645
CPC分类号： C12P23/00 , A23L5/44 , A23L33/155 , A23V2002/00 , A61K31/015 , A23V2250/702
摘要： The present invention provides a method for producing and purifying β-carotene by Blakeslea trispora fermentation and use thereof. The method comprises the following steps: a) separately inoculating the Blakeslea trispora strains onto a PDA culture medium so as to obtain a spore suspension; b) propagating spores in a seeding tank so as to obtain seeds for fermentation; c) inoculating the seeds for fermentation onto a fermenter and fermenting said seeds; d) adjusting the fermentation liquid to be basic by using an organic or inorganic base, and filtering so as to obtain wet mycelia; e) treating the wet mycelia with a hydrophobic non-polar organic solvent; f) mixing the wet mycelia with an organic solvent of ester and obtaining a concentrated solution by extracting; g) adding a saturated monohydric alcohol into the concentrated solution, and filtering and crystallizing so as to obtain pure ss-carotene. The content of the ss-carotene in the present invention exceeds 96%, and the yield is above 85%.
摘要翻译：本发明提供了生产和由三孢布拉霉的发酵净化²胡萝卜素及其使用方法。该方法包括以下步骤：a）分别接种三孢布拉霉的菌株于PDA培养基，以便获得的孢子悬浮液; b）中传播的种子罐孢子，以便获得用于发酵种子; c）中接种发酵的种子到发酵罐中并发酵所述种子; D）调节发酵液是通过使用有机或无机碱来，并过滤以得到湿的菌丝体基本; E）治疗与疏水性非极性有机溶剂的湿式菌丝体; f）与在酯的有机溶剂混合的湿菌丝体并通过提取获得浓缩的溶液; 克）加入饱和一元醇的浓缩溶液，过滤并结晶以获得纯的β-胡萝卜素。在本发明中的β-胡萝卜素的含量超过96％，且产率为85％以上。

8. 发明公开

EP2671596A1 PROCESS FOR PRODUCING AQUEOUS SOLUTION CONTAINING FAT-SOLUBLE SUBSTANCE 审中-公开
标题翻译：方法用于生产具有脂溶性物质的水溶液
公开(公告)号：EP2671596A1
公开(公告)日：2013-12-11
申请号：EP12742635.1
申请日：2012-01-31
申请人： Wacker Chemie AG
发明人： TERAO, Keiji , FUKUMI, Hiroshi , NAKATA, Daisuke , UEKAJI, Yukiko , JO, Ayako
IPC分类号： A61K47/40 , A23L1/30 , A23L1/303 , A61K8/73 , A61K9/08 , A61K31/05 , A61K31/07 , A61K31/12 , A61K31/122 , A61K31/192 , A61K31/216 , A61K31/352 , A61K31/381 , A61K35/64 , A61K36/73 , A61K47/14 , A61K47/26 , A61K47/28 , A61K47/34 , A61K47/36
CPC分类号： A61K47/28 , A23L5/43 , A23L33/105 , A23L33/155 , A23P10/30 , A23V2002/00 , A23V2200/00 , A61K8/63 , A61K8/738 , A61K8/86 , A61K31/05 , A61K31/07 , A61K31/12 , A61K31/122 , A61K31/192 , A61K31/216 , A61K31/352 , A61K31/355 , A61K31/381 , A61K31/385 , A61K31/7048 , A61K35/63 , A61K36/73 , A61K36/738 , A61K38/1709 , A61K47/6951 , A61K2800/10 , A61K2800/49 , A61Q19/00 , B82Y5/00 , A61K2300/00 , A23V2200/224 , A23V2250/211 , A23V2250/2112 , A23V2250/2116 , A23V2250/314 , A23V2250/5112 , A23V2250/712
摘要： The purpose of the present invention is to provide a process for producing an aqueous solution containing a fat-soluble substance. A combination of a super dissolution aid, cyclodextrin and a fat-soluble substance or a combination of the super dis-solution aid and a cyclodextrin complex of the fat-soluble substance is used for dissolving the fat-soluble substance, whereby it becomes possible to provide an aqueous solution containing the fat-soluble substance at a high concentration and an aqueous solution having improved transdermal absorbability of the fat-soluble substance contained therein.

9. 发明授权

EP1898725B1 CITRUS FRUIT FIBRES IN EMULSIONS 有权
标题翻译：柑橘纤维乳液
公开(公告)号：EP1898725B1
公开(公告)日：2012-11-21
申请号：EP06762348.8
申请日：2006-07-03
申请人： Cargill, Incorporated
发明人： VANHEMELRIJCK, Jozef, Guido, Roza , MCCRAE, Catharina, Hillagonda
IPC分类号： A23L1/302 , A23L1/303 , A23L2/52 , A21D2/36 , A23L1/308
CPC分类号： A23L2/52 , A23L33/15 , A23L33/155 , A23L33/22

10. 发明公开

EP2517699A1 Composition for prevention and treatment of arthritis 审中-公开
标题翻译： Zusammensetzung zur Vorbeugung und Behandlung von Arthritis
公开(公告)号：EP2517699A1
公开(公告)日：2012-10-31
申请号：EP11164261.7
申请日：2011-04-29
申请人： Biotechnobel SA
发明人： Bathaei, Seyed Saied
IPC分类号： A61K31/05 , A61K31/07 , A61K31/352 , A61K31/355 , A61K31/59 , A61K31/702 , A61K31/715 , A61K38/43 , A61P19/02 , A23L1/30 , A23L1/305 , A23L1/303
CPC分类号： A61K31/198 , A23L5/00 , A23L29/06 , A23L29/30 , A23L33/105 , A23L33/125 , A23L33/15 , A23L33/155 , A23L33/16 , A23L33/17 , A23L33/175 , A23L33/21 , A23V2002/00 , A61K31/05 , A61K31/352 , A61K31/355 , A61K31/59 , A61K31/702 , A61K31/715 , A61K38/063 , A61K38/465 , A61K38/47 , A61K38/48 , A61K45/06 , A23V2250/60 , A23V2250/70 , A23V2250/51 , A23V2250/28 , A23V2250/2132 , A61K2300/00 , A61K31/07
摘要： A pharmaceutical or neutraceutical composition for preventing or treating arthritis containing a pharmaceutically effective amount of at least a prebiotic dietary fibre, a polyphenol, an antioxidant, an amylolytic enzyme and a liposoluble vitamin.
摘要翻译：一种用于预防或治疗关节炎的药物或营养组合物，所述关节炎含有药学有效量的至少一种益生元饮食纤维，多酚，抗氧化剂，淀粉分解酶和脂溶性维生素。

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