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    • 10. 发明公开
    • Method of preparing low allergic natural rubber latex and deproteinized natural rubber latex, and low allergic natural rubber and deproteinized natural rubber
    • 一种用于生产天然橡胶胶乳的低过敏作用和脱蛋白天然橡胶胶乳和天然橡胶胶乳的低过敏作用和过程脱蛋白天然橡胶胶乳
    • EP1205491A3
    • 2003-05-21
    • EP01309420.6
    • 2001-11-07
    • Sumitomo Rubber Industries, Ltd.Kao Corporation
    • Ichikawa, Naoya, c/o Sumitomo Rubber Ind. Ltd.Miyamoto, Yoshiaki, c/o Sumitomo Rubber Ind. Ltd.Hayashi, Masaharu, c/o Kao Corporation
    • C08C1/04C08C1/02
    • C08C1/04Y10S528/932Y10S528/934Y10S528/935
    • A method of preparing a low allergic natural rubber latex which is less likely to cause allergy, comprising adding a protease having an exopeptidase activity to a natural rubber latex and aging the natural rubber latex, thereby to decompose a protein in the latex to such a degree that the protein and its decomposition products, which have a number-average molecular weight of 4500 or more, are not detectable; a method of preparing a deproteinized natural rubber latex which is less likely to cause allergy, comprising adding an alkali protease to a natural rubber latex, thereby to decompose a protein in the latex, adding a protease having an exopeptidase activity, thereby further to decompose the protein and decomposition products thereof in the latex, and removing the protein and the decomposition products thereof; a low allergic natural rubber obtained by a decomposition treatment of a protein, wherein the protein and its protein decomposition products, which have a number-average molecular weight of 4500 or more, are not detectable; and a deproteinized natural rubber obtained by decomposition and removal treatment of a protein, wherein the content of the protein is 0.02% or less in terms of nitrogen content, an absorption at 3280 cm -1 is not recognizable in an infrared absorption spectrum, and the protein and a protein decomposition product, which have a number-average molecular weight of 4500 or more, are not detectable.
    • 制备低过敏性天然橡胶胶乳的方法,所有这些都不太可能引起过敏,包括加入具有外肽酶活性的天然橡胶胶乳和老化天然橡胶胶乳中的蛋白酶,从而以分解乳胶中的蛋白质,以寻求一个度 做了蛋白及其分解产物,其具有4500或更高的数均分子量,都不能检测 制备脱蛋白天然橡胶胶乳的所有这是不太可能引起过敏,包括向碱性蛋白酶至天然橡胶胶乳,从而以分解乳胶中的蛋白质,将具有到外肽酶活性的蛋白酶的方法,从而进一步分解 蛋白和胶乳或其分解产物,以及去除所述蛋白质以及它们的分解产物; 低过敏性天然橡胶通过蛋白质的分解处理而获得,worin蛋白质及其蛋白的分解产物,其具有4500或更高的数均分子量,都不能检测 并通过分解和蛋白质的去除处理而得到,worin蛋白质的含量脱蛋白天然橡胶是0:在氮含量计02%或更少,以吸收在3280厘米<-1>不在到红外吸收光谱识别的, 并且蛋白质和蛋白质分解物,其具有4500或更高的数均分子量,是不可检测的。