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1. 发明公开

EP3043864A2 METHODS AND SYSTEMS FOR BEAM INTENSITY-MODULATION TO FACILITATE RAPID RADIATION THERAPIES 无效转让
标题翻译：方法和系统的辐射强度调制激活FAST RADIO疗法
公开(公告)号：EP3043864A2
公开(公告)日：2016-07-20
申请号：EP14876485.5
申请日：2014-09-11
申请人： The Board of Trustees of the Leland Stanford Junior University
发明人： BHARADWAJ, Vinod , DOLGASHEV, Valery, A. , FAHRIG, Rebecca , LOO, Billy, Wiseman , MAXIM, Peter, G. , TANTAWI, Sami , LIMBORG, Cecile , NICOLAS, Ludovic
IPC分类号： A61N5/10 , H05H1/00
CPC分类号： A61N5/1084 , A61N5/1039 , A61N5/1043 , A61N5/1045 , A61N5/1064 , A61N5/1067 , A61N5/1078 , A61N5/1081 , A61N7/02 , A61N2005/1055 , A61N2005/1058 , A61N2005/1076 , A61N2005/1089 , A61N2005/1091 , A61N2005/1098 , H05H9/048 , H05H2007/048
摘要： Methods and system for facilitating rapid radiation treatments are provided herein and relate in particular to radiation generation and delivery, electron source design, beam control and shaping/intensity-modulation. The methods and systems described herein are particularly advantageous when used with a compact high-gradient, very high energy electron (VHEE) accelerator and delivery system (and related processes) capable of treating patients from multiple beam directions with great speed, using all-electromagnetic or radiofrequency deflection steering is provided; or when used with a high-current electron accelerator system of energy range more conventionally used in photon radiation therapy to produce much faster delivery of intensity-modulated photon radiation therapy, that can in both cases deliver an entire dose or fraction of high-dose radiation therapy sufficiently fast to freeze physiologic motion, yet with a equal or better degree of dose conformity or sculpting compared to conventional photon therapy.
摘要翻译：在提供的方法和系统，用于促进快速放射治疗，特别是涉及到放射线生成和传递，电子源设计，光束控制和整形/强度调制。在所描述的方法和系统是特别有利的。当具有结构紧凑的高梯度使用的，非常高的能量的电子（VHEE）加速器和递送系统（和相关过程）能够治疗从以极快的速度多个波束方向的患者，使用的所有电磁或射频偏转转向设置; 或当与能量范围的高电流电子加速器系统在光子放射疗法更常规使用的用于产生强度调制的光子辐射治疗的快得多输送，并能在这两种情况下购买兑现整个剂量或高剂量辐射的分数充分治疗几乎冻结生理运动，但与相同或更好的程度剂量适形性或雕刻的相比于常规光子疗法。

2. 发明授权

EP2750486B1 Standing wave electron linear accelerators with continuously adjustable energy and method thereof 有权
公开(公告)号：EP2750486B1
公开(公告)日：2018-10-10
申请号：EP13198316.5
申请日：2013-12-19
申请人： Tsinghua University , Nuctech Company Limited
发明人： Tang, Chuanxiang , Zhang, Zhe , Jin, Qingxiu , Shi, Jiaru , Chen, Huaibi , Huang, Wenhui , Zheng, Shuxin , Liu, Yaohong
IPC分类号： H05H9/04
CPC分类号： H05H9/04 , H05G1/32 , H05G2/00 , H05H7/12 , H05H7/22 , H05H9/048
摘要： A standing wave electron linear accelerating apparatus and a method thereof are disclosed. The apparatus comprises an electron gun configured to generate electron beams; a pulse power source configured to provide a primary pulse power signal; a power divider coupled downstream from the pulse power source and configured to divide the primary pulse power signal outputted from the pulse power source into a first pulse power signal and a second pulse power signal; a first accelerating tube configured to accelerating the electron beams with the first pulse power signal; a second accelerating tube configured to accelerate the electron beams with the second pulse power signal; a phase shifter configured to continuously adjust a phase difference between the first pulse power signal and the second pulse power signal so as to generate accelerated electron beams with continuously adjustable energy at output of the second accelerating tube.

3. 发明公开

EP3231260A1 TEILCHENBESCHLEUNIGER ZUR ERZEUGUNG EINES GEBUNCHTEN TEILCHENSTRAHLS 审中-公开
标题翻译： TEILCHENBESCHLEUIGER ZUR ERZEUGUNG EINES GEBUNCHTEN TEILCHENSTRAHLS
公开(公告)号：EP3231260A1
公开(公告)日：2017-10-18
申请号：EP15816386.5
申请日：2015-12-09
申请人： Ampas GmbH
发明人： ARNOLD, Wolfgang
IPC分类号： H05H7/02 , H05H9/04
CPC分类号： H05H7/02 , H05H9/048 , H05H2007/025
摘要： The invention relates to a particle accelerator (10, 100, 102, 104, 106), in particular an electron accelerator, for generating a bunched particle beam, and to a method for operating such a particle accelerator (10, 100, 102, 104, 106). The particle accelerator (10, 100, 102, 104, 106) comprises an HF source (14) and a directional coupler (20) for branching an HF power of the HF source (14) of an HF side (32) to at least one first and one second HF power coupler (26a, 26b) of a cavity side (34) for coupling HF power in at least one accelerator cavity (18). According to the invention, on the cavity side (34) between the directional coupler (20) and the second HF power coupler (26b), a non-reciprocal phase shifter (22, 30) is interposed, and on the HF side (32) a HF load (16) is connected to the directional coupler (20). The non-reciprocal phase shifter (22, 30) is configured to conduct a reflected HF wave of the second HF power coupler (26) in a phase-delayed manner in the direction of the directional coupler (20) such that a destructive interference of the reflected HF waves of the first and second power coupler (26a, 26b) in the directional coupler (20) in the direction of the HF source (14) on the HF side (32) is obtained.
摘要翻译：本发明涉及用于产生聚束粒子束的粒子加速器（10,100,102,104,106），尤其是电子加速器，以及用于操作这种粒子加速器（10,100,102,104）的方法，106）。粒子加速器（10,100,102,104,106）包括HF源（14）和定向耦合器（20），用于将HF侧（32）的HF源（14）的HF功率分支到至少一个用于耦合至少一个加速器空腔（18）中的HF功率的空腔侧（34）的一个第一和一个第二HF功率耦合器（26a，26b）。根据本发明，在定向耦合器（20）和第二HF功率耦合器（26b）之间的空腔侧（34）上插入非互易移相器（22,30），并且在HF侧（32 ）HF负载（16）连接到定向耦合器（20）。该非互易移相器（22,30）被配置成以相位延迟方式在定向耦合器（20）的方向上传导第二HF功率耦合器（26）的反射HF波，使得获得在HF侧（32）上的HF源（14）的方向上定向耦合器（20）中的第一和第二功率耦合器（26a，26b）的反射HF波。

4. 发明公开

EP1697922A4 STANDING WAVE PARTICLE BEAM ACCELERATOR 有权转让
标题翻译：带有轴的粒子束加速器
公开(公告)号：EP1697922A4
公开(公告)日：2014-07-02
申请号：EP04815329
申请日：2004-12-21
申请人： VARIAN MED SYS INC
发明人： MEDDAUGH GARD E , TRAIL MARK E , WHITTUM DAVID
IPC分类号： G10K11/00 , H05H9/04
CPC分类号： H05H9/048
摘要： An accelerator for accelerating a particle beam includes a main body having a plurality of electromagnetic cavities coupled in series, and a first coupling body having a first side cavity coupled to one of the electromagnetic cavities through a first opening, and to another of the electromagnetic cavities through a second opening, wherein the first opening and the second opening have different configurations. The accelerator further includes a pair of conductive capacitively coupled noses secured to side walls of the first coupling body, wherein the pair of noses have equal lengths.
摘要翻译：用于加速粒子束的加速器包括具有串联耦合的多个电磁空腔的主体和具有通过第一开口连接到电磁空腔中的一个的第一侧腔的第一联接体以及另一个电磁腔通过第二开口，其中第一开口和第二开口具有不同的构造。加速器还包括固定到第一联接体的侧壁的一对导电电容耦合的鼻，其中所述一对鼻具有相等的长度。

5. 发明公开

EP2687067A2 LINEAR ACCELERATOR 有权
标题翻译：直线加速器
公开(公告)号：EP2687067A2
公开(公告)日：2014-01-22
申请号：EP12731293.2
申请日：2012-03-13
申请人： Elekta AB (PUBL)
发明人： ALLEN, John , LARGE, Terry Arthur
IPC分类号： H05H7/18 , H05H7/22 , H05H9/04
CPC分类号： H05H9/048 , H05H7/18 , H05H7/22 , H05H2007/225
摘要： The present invention provides a linear accelerator in which a rotatable conductive vane is employed to vary the electromagnetic coupling between adjacent accelerating cells. The vane is sealed off from the rest of the linear accelerator by an insulating partition, so the pressure around the vane can be higher than in the rest of the accelerator. This greatly simplifies the mechanisms which may be used to control the rotation of the vane, allowing a higher bakeout temperature in manufacture and a higher rate of rotation in use.

6. 发明公开

EP2684430A1 ELECTRON SOURCE FOR LINEAR ACCELERATORS 有权
标题翻译： ELEKTRONENQUELLEFÜRLINEARBESCHLEUNIGER
公开(公告)号：EP2684430A1
公开(公告)日：2014-01-15
申请号：EP12708499.4
申请日：2012-03-09
申请人： Elekta AB (PUBL)
发明人： LARGE, Terry, Arthur
IPC分类号： H05H9/00 , H01J25/34 , H01J1/46 , H01J23/075
CPC分类号： H01J25/34 , H01J3/02 , H01J23/075 , H05H9/048 , H05H2007/084
摘要： The present invention provides an electron gun (12) comprising a cathode (20), for generating electrons; an anode (22); an intermediate electrode (24), located between the cathode and the anode; and a controller (14). The controller applies an electrical potential to said intermediate electrode, analysing a resultant electrical parameter to determine the integrity of said intermediate electrode; and controls the electron gun to emit a pulse of electrons.
摘要翻译：本发明提供一种电子枪，其包括用于产生电子的阴极; 阳极; 位于阴极和阳极之间的中间电极; 和控制器。控制器向所述中间电极施加电势，分析所得的电参数以确定所述中间电极的完整性; 并控制电子枪发射电子脉冲。

7. 发明公开

EP4391730A3 VOLTAGE REGULATOR CIRCUITS, RADIATION DEVICES AND RADIATION SYSTEMS INCLUDING THE SAME 审中-实审
公开(公告)号：EP4391730A3
公开(公告)日：2024-09-04
申请号：EP23216794.0
申请日：2023-12-14
申请人： Varian Medical Systems Inc
发明人： POEHLMANN-MARTINS, Flavio , SABEV, Ogy , MAIN, William Thompson , CAHILL, Alexander , ALIBAZI BEHBAHANI, Reza , PAI, Raj
IPC分类号： H05H9/00 , H05H7/02 , H05H9/04
CPC分类号： H05H7/02 , H05H9/048
摘要： A radiation system includes a modulator (218) and at least one voltage regulator circuit (30, 302, 402, 602, 1002, 1202, 1402). The modulator (218) is configured to output a voltage for operation of a magnetron (216) and an electron gun (220) of the radiation system. The at least one voltage regulator circuit (30, 302, 402, 602, 1002, 1202, 1402) is electrically connected between the modulator and at least one of the magnetron (216) or the electron gun (220), and configured to control a magnitude of the voltage output from the modulator (218) for operation of the magnetron (216) and the electron gun (220).

8. 发明公开

EP3043864A4 METHODS AND SYSTEMS FOR BEAM INTENSITY-MODULATION TO FACILITATE RAPID RADIATION THERAPIES 无效转让
标题翻译： VERFAHREN UND SYSTEME ZUR STRAHLENINTENSENSITTSMODULATION ZUR AKTIVIERUNG SCHNELLER RADIOTHERAPIEN
公开(公告)号：EP3043864A4
公开(公告)日：2017-07-26
申请号：EP14876485
申请日：2014-09-11
申请人： UNIV LELAND STANFORD JUNIOR
发明人： BHARADWAJ VINOD , DOLGASHEV VALERY A , FAHRIG REBECCA , LOO BILLY WISEMAN , MAXIM PETER G , TANTAWI SAMI , LIMBORG CECILE , NICOLAS LUDOVIC
IPC分类号： A61N5/10 , G21K5/04 , H05H1/00 , H05H7/04 , H05H9/04 , H05H15/00
CPC分类号： A61N5/1084 , A61N5/1039 , A61N5/1043 , A61N5/1045 , A61N5/1064 , A61N5/1067 , A61N5/1078 , A61N5/1081 , A61N7/02 , A61N2005/1055 , A61N2005/1058 , A61N2005/1076 , A61N2005/1089 , A61N2005/1091 , A61N2005/1098 , H05H9/048 , H05H2007/048
摘要： Methods and system for facilitating rapid radiation treatments are provided herein and relate in particular to radiation generation and delivery, electron source design, beam control and shaping/intensity-modulation. The methods and systems described herein are particularly advantageous when used with a compact high-gradient, very high energy electron (VHEE) accelerator and delivery system (and related processes) capable of treating patients from multiple beam directions with great speed, using all-electromagnetic or radiofrequency deflection steering is provided; or when used with a high-current electron accelerator system of energy range more conventionally used in photon radiation therapy to produce much faster delivery of intensity-modulated photon radiation therapy, that can in both cases deliver an entire dose or fraction of high-dose radiation therapy sufficiently fast to freeze physiologic motion, yet with a equal or better degree of dose conformity or sculpting compared to conventional photon therapy.
摘要翻译：本文提供了用于促进快速辐射治疗的方法和系统，并且具体涉及辐射产生和输送，电子源设计，束控制和成形/强度调制。本文描述的方法和系统当与紧凑的高梯度，超高能量电子（VHEE）加速器和递送系统（以及相关处理）一起使用时特别有利，其能够使用全电磁波或提供射频偏转转向; 或者当与通常用于光子放射疗法的能量范围的高电流电子加速器系统一起使用以产生更快速的强度调制光子放射治疗的递送时，可以在两种情况下递送全剂量或部分高剂量辐射治疗足以快速冻结生理运动，但与常规光子疗法相比，具有相同或更好的剂量一致性或雕刻程度。

9. 发明公开

EP3043863A1 ARRAYS OF ACCELERATING STRUCTURES AND RAPID IMAGING FOR FACILITATING RAPID RADIATION THERAPIES 有权转让
标题翻译：加速结构安排和快速成像FAST RADIOTHERAPIE
公开(公告)号：EP3043863A1
公开(公告)日：2016-07-20
申请号：EP14844431.8
申请日：2014-09-11
申请人： The Board of Trustees of the Leland Stanford Junior University
发明人： FAHRIG, Rebecca , LOO, Billy Wiseman , MAXIM, Peter G. , TANTAWI, Sami
IPC分类号： A61N5/10
CPC分类号： A61N5/1084 , A61N5/1039 , A61N5/1043 , A61N5/1045 , A61N5/1064 , A61N5/1067 , A61N5/1078 , A61N5/1081 , A61N7/02 , A61N2005/1055 , A61N2005/1058 , A61N2005/1076 , A61N2005/1089 , A61N2005/1091 , A61N2005/1098 , H05H9/048 , H05H2007/048
摘要： Methods and system for facilitating rapid radiation treatments are provided herein and relate in particular to radiation generation and delivery, electron source design, beam control and shaping/intensity-modulation. The methods and systems described herein are particularly advantageous when used with a compact high-gradient, very high energy electron (VHEE) accelerator and delivery system (and related processes) capable of treating patients from multiple beam directions with great speed, using all-electromagnetic or radiofrequency deflection steering is provided; or when used with a high-current electron accelerator system of energy range more conventionally used in photon radiation therapy to produce much faster delivery of intensity-modulated photon radiation therapy, that can in both cases deliver an entire dose or fraction of high-dose radiation therapy sufficiently fast to freeze physiologic motion, yet with a equal or better degree of dose conformity or sculpting compared to conventional photon therapy.
摘要翻译：在提供的方法和系统，用于促进快速放射治疗，特别是涉及到放射线生成和传递，电子源设计，光束控制和整形/强度调制。在所描述的方法和系统是特别有利的。当具有结构紧凑的高梯度使用的，非常高的能量的电子（VHEE）加速器和递送系统（和相关过程）能够治疗从以极快的速度多个波束方向的患者，使用的所有电磁或射频偏转转向设置; 或当与能量范围的高电流电子加速器系统在光子放射疗法更常规使用的用于产生强度调制的光子辐射治疗的快得多输送，并能在这两种情况下购买兑现整个剂量或高剂量辐射的分数充分治疗几乎冻结生理运动，但与相同或更好的程度剂量适形性或雕刻的相比于常规光子疗法。

10. 发明公开

EP2938169A1 LINEAR ACCELERATOR 有权
标题翻译： LINEARBESCHLEUNIGER
公开(公告)号：EP2938169A1
公开(公告)日：2015-10-28
申请号：EP15164871.4
申请日：2015-04-23
申请人： Elekta AB (publ)
发明人： Harasimowicz, Janusz , Shinton, Ian
IPC分类号： H05H7/22 , H05H9/04
CPC分类号： H05H7/22 , H05H7/02 , H05H9/00 , H05H9/048 , H05H2007/025 , H05H2007/227 , H05H2277/11
摘要： A linear accelerator is disclosed, having a series of interconnected cavities through at least some of which an rf signal and an electron beam are sent, comprising at least one variable coupler projecting into a cavity of the series, a control apparatus adapted to interpret an electrical signal from the coupler and derive diagnostic information as to the electron beam therefrom, wherein the control apparatus is further adapted to vary the interaction of the at least one coupler with the rf signal in dependence on the diagnostic information. Thus, the accelerator properties can be adjusted by encouraging or inciting an Higher-Order Mode ("HOM") having a desired effect such as bunching and/or deflecting. The coupler could be rotateable, and partially or fully retractable, to allow its influence to be adjusted and/or for it to be removed from service when not needed. Several such probes could be available, approaching the cavity from different directions or at different locations, or approaching different cavities. The coupler can be asymmetric, in order to exert an appropriate influence on the cavity and provoke a useful HOM. For example, it can be elongate with at least one directional deviation, such as a hockey stick. Generally, however, the appropriate shape for the coupler will be dependent on the shape of the cavity with which it is working and the specific HOMs that are to be excited.
摘要翻译：公开了一种线性加速器，其具有通过至少一些其中的一些RF信号和电子束被发送的一系列互连的空腔，包括突出到该系列的空腔中的至少一个可变耦合器，适于解释电气来自耦合器的信号并从其中导出关于电子束的诊断信息，其中控制装置还适于根据诊断信息改变至少一个耦合器与rf信号的相互作用。因此，可以通过鼓励或煽动具有期望效果的高阶模式（“HOM”）来调节加速器特性，例如聚束和/或偏转。联接器可以是可旋转的，并且部分地或完全可缩回的，以允许其影响被调整和/或在不需要的时候使其脱离服务。可以使用若干这样的探针，从不同方向或不同位置接近腔，或接近不同的腔。耦合器可以是不对称的，以便对腔体施加适当的影响并引起有用的HOM。例如，它可以用至少一个方向偏移来延伸，例如曲棍球棒。然而，通常，耦合器的适当形状将取决于其正在工作的腔体的形状和要激发的特定HOM。

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