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1. 发明授权

EP2803358B1 10,10-Dialkyl prostanoic acid derivatives as agents for lowering intraocular pressure 有权
标题翻译： 10,10-Dialkyl-Prostansäurederivateals Mittel zur Verringerung des Intraokulardrucks
公开(公告)号：EP2803358B1
公开(公告)日：2017-05-03
申请号：EP14177792
申请日：2004-02-06
申请人： ALLERGAN INC
发明人： DONDE YARIV , NGUYEN JEREMIAH H
IPC分类号： A61K31/5575 , A61P27/06 , C07C405/00 , C07D333/56 , C07D333/62 , C07D409/08
CPC分类号： C07D333/62 , A61K31/5575 , C07C405/00 , C07D333/56 , C07D409/08

2. 发明公开

EP3089230A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 有权
标题翻译：有机电致发光元件的材料和使用相同的有机电致发光元件
公开(公告)号：EP3089230A1
公开(公告)日：2016-11-02
申请号：EP14875046.6
申请日：2014-11-05
申请人： Nippon Steel & Sumikin Chemical Co., Ltd.
发明人： OGAWA Junya , TADA Masashi , UEDA Tokiko , KAI Takahiro
IPC分类号： H01L51/50
CPC分类号： H01L51/008 , C07D333/76 , C07D409/04 , C07D409/08 , C07D409/14 , C07F5/027 , C09K11/025 , C09K11/06 , C09K2211/1007 , C09K2211/1029 , C09K2211/185 , H01L51/0067 , H01L51/0072 , H01L51/0074 , H01L51/0081 , H01L51/0085 , H01L51/5016 , H01L51/5024 , H01L51/5072 , H01L51/5096 , H01L51/5206 , H01L51/5234
摘要： Disclosed are an organic electroluminescent device (organic EL device) having improved luminous efficiency, sufficiently secured driving stability, and a simple construction, and a material for an organic EL device. The material for an organic EL device includes a carborane compound having a structure in which at least one carborane ring and at least one dibenzothiophene ring are present, and the at least one carborane ring is bonded to the at least one dibenzothiophene ring at position 1, 2, or 3. In addition, the organic EL device includes, between an anode and a cathode laminated on a substrate, at least one organic layer, in which the at least one organic layer includes the carborane compound.
摘要翻译：公开了一种具有改进的发光效率，充分确保驱动稳定性和简单结构的有机电致发光器件（有机EL器件）和用于有机EL器件的材料。用于有机EL器件的材料包括具有其中存在至少一个碳硼环和至少一个二苯并噻吩环的结构的碳硼烷化合物，并且所述至少一个碳硼环与至少一个二苯并噻吩环在1位结合，另外，有机EL元件在层叠于基板上的阳极和阴极之间具有至少一层有机层，所述有机层包含碳硼烷化合物。

3. 发明授权

EP1926721B1 THIOPHENE AND THIAZOLE SUBSTITUTED TRIFLUOROETHANONE DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS 有权
标题翻译：噻吩和THIAZOLSUBSTITUIERTE TRIFLUORETHANONDERIVATE作为抑制剂组蛋白去乙酰化酶（HDAC抑制剂）
公开(公告)号：EP1926721B1
公开(公告)日：2016-05-04
申请号：EP06779628.4
申请日：2006-09-05
申请人： MSD Italia S.r.l.
发明人： FERRIGNO, Federica , JONES, Philip , MURAGLIA, Ester , ONTORIA ONTORIA, Jesus Maria , SCARPELLI, Rita
IPC分类号： C07D333/38 , C07D333/34 , C07D277/56 , C07D409/12 , C07D417/12 , C07D413/14 , C07D471/04 , C07D487/04 , A61K31/381 , A61K31/426 , A61P25/18 , A61P25/28 , A61P35/00
CPC分类号： C07D409/08 , C07D277/56 , C07D333/34 , C07D333/38 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D487/08 , C07D491/10 , C07D495/04 , C12Q1/34

4. 发明公开

EP2902402A4 WATER-SOLUBLE PHOTOCHROMIC MOLECULE 审中-公开
标题翻译： WASSERLÖSLICHESPHOTOCHROMESMOLEKÜL
公开(公告)号：EP2902402A4
公开(公告)日：2016-04-13
申请号：EP13837714
申请日：2013-09-06
申请人： RIKKYO EDUCATIONAL CORP , JOSHO GAKUEN EDUCATIONAL FOUNDATION
发明人： TOKIWA HIROAKI , IRIE MASAHIRO , IKEDA KIYOSHI , OTSUBO TADAMUNE
IPC分类号： C07H15/26
CPC分类号： C07H15/26 , C07D333/38 , C07D333/54 , C07D409/08 , C09K9/02
摘要： A diarylethene compound having high water-solubility is provided, and the compound is a diarylethene compound of formula (I) wherein, Sg is a monovalent sugar-type residue consisting of a sugar-type compound (in which some of hydroxyl groups may be protected) selected from a group consisting of a six-membered ring sugar, a five-membered ring sugar, cyclitol and oligosaccharides containing a six-membered ring sugar, a five-membered ring sugar, or cyclitol and excluding an hydroxyl group; U is -(CH 2 )n-, -CH 2 -U'-, or -C(=O)- (wherein, n is an integer of 1 to 5, U' is a C1-C10 alkyl group binding to Ar); and Ar is a group represented by formula (A1) or (A2); wherein, X is S, SO 2 , NR 3 (R 3 is a C1-C3 alkyl group) or O, R is C1-C4 alkyl group, R 1 and R 2 are independently a C1-C3 alkyl group, a is 0 or 1, b is an integer of 0-3, and * represents a bond with U); Y is a hydrogen atom or a halogen atom; m is an integer of 5-7.
摘要翻译：提供了具有高水溶性的二芳基乙烯化合物，该化合物是式（I）的二芳基乙烯化合物，其中Sg是由糖型化合物（其中一些羟基可被保护的）形成的单价糖型残基）选自六元环糖，五元环糖，环状醇和含有六元环糖，五元环糖或环醇的寡糖并且不包括羟基的组; U是 - （CH 2）n - ， - CH 2 -U'-或-C（= O） - （其中，n是1至5的整数，U'是与Ar结合的C 1 -C 10烷基）; 和Ar是由式（A1）或（A2）表示的基团。其中，X是S，SO 2，NR 3（R 3是C 1 -C 3烷基）或O，R是C 1 -C 4烷基，R 1和R 2独立地是C 1 -C 3烷基，a是0 或1，b为0-3的整数，*表示与U的键）; Y是氢原子或卤素原子; m是5-7的整数。

5. 发明公开

EP2542538A1 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES 有权
标题翻译： 6-酰基-1,2,4-三嗪-3,5-二酮衍生物和除草剂
公开(公告)号：EP2542538A1
公开(公告)日：2013-01-09
申请号：EP11800564.4
申请日：2011-05-26
申请人： Kumiai Chemical Industry Co., Ltd. , Ihara Chemical Industry Co., Ltd.
发明人： SHIBAYAMA, Atsushi , KAJIKI, Ryu , KOBAYASHI, Masami , MITSUNARI, Takashi , NAGAMATSU, Atsushi
IPC分类号： C07D253/06 , A01N43/707 , A01N43/80 , A01N43/84 , A01N47/02 , A01P13/02 , C07D401/04 , C07D403/04 , C07D403/06 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04
CPC分类号： C07D253/075 , A01N43/707 , A01N43/78 , A01N43/80 , A01N43/84 , A01N47/02 , C07D401/04 , C07D401/06 , C07D401/08 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/08 , C07D403/12 , C07D405/04 , C07D405/06 , C07D405/08 , C07D405/10 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/06 , C07D409/08 , C07D409/12 , C07D411/04 , C07D411/08 , C07D411/10 , C07D411/12 , C07D411/14 , C07D413/04 , C07D413/08 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/08 , C07D417/10 , C07D417/12 , C07D417/14
摘要： Disclosed are compounds exhibiting sufficient herbicidal activity at low application dosage when they are applied to soils and foliage, and an agrochemical composition using the same, in particular herbicides. The compounds are triazine derivatives represented by following Formula 1 or salts thereof, and the herbicides containing them: [Chem. 28] wherein in the formula, R1 represents a hydrogen atom; a C1-C12 alkyl group; a C2-C6 alkenyl group, etc., R2 represents a C1-C12 alkyl group, etc., Y and Z represent an oxygen atom or a sulfur atom, and A represents a 5- or 6-membered cyclic group which may contain a nitrogen atom, an oxygen atom, or a sulfur atom.

6. 发明公开

EP2331531A2 THERAPEUTIC SUBSTITUTED PYRROLES 有权
标题翻译： THERAPEUTIC取代吡咯
公开(公告)号：EP2331531A2
公开(公告)日：2011-06-15
申请号：EP09804086.8
申请日：2009-08-18
申请人： Allergan, Inc.
发明人： OLD, David W.
IPC分类号： C07D407/08
CPC分类号： C07D207/333 , C07D407/08 , C07D409/06 , C07D409/08 , C07D409/14 , C07D413/14
摘要： Disclosed herein is a compound represented by a Formula (I). Therapeutic methods, compositions, and medicaments related thereto are also disclosed.

7. 发明公开

EP2170345A1 THERAPEUTIC SUBSTITUTED CYCLOPENTANES FOR REDUCING INTRAOCULAR PRESSURE 有权
标题翻译：治疗替代疗法CYROPENTANE ZUR REDUZIERUNG DES INTRAOKULAREN DRUCKS
公开(公告)号：EP2170345A1
公开(公告)日：2010-04-07
申请号：EP08781152.7
申请日：2008-06-30
申请人： ALLERGAN, INC.
发明人： OLD, David, W. , NGO, Vinh, X. , HOLOBOSKI, Mark , POSNER, Mari, F.
IPC分类号： A61K31/5575 , A61K31/559 , C07C405/00 , A61P27/06
CPC分类号： C07D409/08 , A47G19/06 , A61K31/38 , A61K31/381 , A61K31/41 , A61K31/5575 , A61K31/559 , C07C405/00 , C07C2601/08 , C07D257/04 , C07D277/56 , C07D333/10 , C07D333/40
摘要： Disclosed herein are compounds having the formula (I) wherein a dashed line represents the presence or absence of a bond; Y is an organic acid functional group, or an amide or ester thereof; or Y is hydroxymethyl or an ether thereof; or Y is a tetrazolyl functional group; A is —(CH2)6—, cis —CH2CH═CH—(CH2)3—, or —CH2C═C—(CH2)3—, wherein 1 or 2 carbon atoms may be replaced by S or O; or A is —(CH2)m—Ar—(CH2)o— wherein Ar is interarylene or heterointerarylene, the sum of m and o is 1, 2, 3, or 4, and wherein 1 —CH2— may be replaced by S or O, and 1 —CH2—CH2— may be replaced by —CH═CH— or —C≡C—; U1 and U2 are independently selected from —H, ═O, —OH, —F, —Cl, and —CN; and B is aryl or heteroaryl, for use as acular hypotensive agent.
摘要翻译：本文公开了具有式（I）的化合物，其中虚线表示键的存在或不存在; Y是有机酸官能团，或其酰胺或酯; 或Y为羟甲基或其酯; 或Y为四唑基官能团; A是 - （CH 2）6 - ，顺式-CH 2 CH = CH-（CH 2）3 - 或-CH 2C≡C-（CH 2）3 - ，其中1或2个碳原子可被S或O取代; 或A是 - （CH 2）m -Ar-（CH 2）o - ，其中Ar是亚芳基或杂亚环烷基，m和o的总和是1,2,3或4，并且其中1 -CH 2可以被 S或O和1 -CH 2 -CH 2 - 可以被-CH = CH-或-C≡C-取代; U1和U2独立地选自-H，= O，-OH，-F，-Cl和-CN; 和B是芳基或杂芳基，用作眼压降低剂。

8. 发明公开

EP1565436A2 3-AMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS 有权转让
标题翻译： 3-氨基吡啶衍生物ALS MODULATOREN VON CHEMOKINREZEPTOREN
公开(公告)号：EP1565436A2
公开(公告)日：2005-08-24
申请号：EP03790120.4
申请日：2003-11-26
申请人： INCYTE CORPORATION
发明人： XUE, Chu-Biao , METCALF, Brian , FENG, Hao , CAO, Ganfeng , HUANG, Taishing , ZHENG, Changsheng , ROBINSON, Darius, J. , HAN, Amy, Qi
IPC分类号： C07D207/14
CPC分类号： C07D491/107 , C07D207/14 , C07D401/08 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/08 , C07D403/10 , C07D405/04 , C07D405/08 , C07D405/10 , C07D405/14 , C07D409/08 , C07D413/08 , C07D413/10 , C07D413/14 , C07D417/08 , C07D417/10 , C07D417/14 , C07D491/10 , C07D495/10
摘要： The present invention relates to 3-aminopyrrolidine derivatives of the formula I: (wherein R1, R2, R3, R4, R5, R6, R7, R8, X, Y and X are as defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of chemokine receptors and more specifically as a modulator of the CCR2 and/or CCR5 receptor. The compounds and compositions of the invention may bind to chemokine receptors, e.g., the CCR2 and/or CCR5 chemokine receptors, and are useful for treating diseases associated with chemokine, e.g., CCR2 and/or CCR5, activity, such as atherosclerosis, restenosis, lupus, organ transplant rejection and rheumatoid arthritis.
摘要翻译：本发明涉及式I的3-氨基吡咯烷衍生物：其中R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8，X，Y和X如本文所定义）其可用作趋化因子受体活性的调节剂。特别地，这些化合物可用作趋化因子受体的调节剂，更具体地可用作CCR2和/或CCR5受体的调节剂。本发明的化合物和组合物可以结合趋化因子受体，例如CCR2和/或CCR5趋化因子受体，并且可用于治疗与趋化因子（例如CCR2和/或CCR5）相关的疾病，例如动脉粥样硬化，再狭窄，狼疮，器官移植排斥和类风湿关节炎。

9. 发明授权

EP0915867B1 DERIVES DU THIENYLCYCLOHEXANE POUR LA SYNTHESE DE THIENYLCYCLOHEXYLES 失效
标题翻译：衍生物二苯基环己烷POUR LA SYNTHESE DE THYENYLCYCLOHEXYLES
公开(公告)号：EP0915867B1
公开(公告)日：2004-10-06
申请号：EP97935617.7
申请日：1997-07-24
申请人： Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.)
发明人： CAZAUX, Jean-Bernard , DAFNIET, Michel , KAMENKA, Jean-Marc , MANGINOT, Eric
IPC分类号： C07D333/24 , C07D333/20 , C07D409/08
CPC分类号： C07D409/08 , C07D333/20 , C07D333/24

10. 发明公开

EP1182203A1 AZOLE COMPOUNDS AND HERBICIDE COMPOSITIONS 审中-公开
标题翻译： AZOLDERIVATE UND HERBIZIDE ZUBEREITUNGEN
公开(公告)号：EP1182203A1
公开(公告)日：2002-02-27
申请号：EP00913081.6
申请日：2000-04-03
申请人： Idemitsu Kosan Co., Ltd.
发明人： SAITOU, Masatoshi , SEKIGUCHI, Hiroki , OGAWA, Shinichiro
IPC分类号： C07D409/08 , A01N43/56
CPC分类号： C07D249/08 , A01N43/56 , A01N43/647 , A01N43/653 , C07D231/12 , C07D231/56 , C07D233/56 , C07D233/68 , C07D409/08
摘要： Azole compounds are represented by the following formula (Ia) or (Ib):

wherein, Q, X, p, R 1 to R 6 , R 12 to R 15 and Z 1 to Z 4 are as defined in the disclosure, and herbicidal compositions contain the azole compounds of formula (Ia) or (Ib) in herbicidally effective amounts. The compounds of the formulae (Ia) and (Ib) are less injurious to cultivated crops and have a broad spectrum of weed control with low application rates.
摘要翻译：唑类化合物由下式（Ia）或（Ib）表示：其中，Q，X，p，R 1至R 6，R 12至R 15和 Z 1至Z 4如本公开中所定义，除草组合物含有除草有效量的式（Ia）或（Ib）的唑类化合物。式（Ia）和（Ib）的化合物对栽培作物的损害较小，具有广泛的杂草控制，施用量低。

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