专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

EP2687278B1 Methods for recovering and analyzing amines 失效
公开(公告)号：EP2687278B1
公开(公告)日：2018-05-30
申请号：EP13176179.3
申请日：2013-07-11
申请人： Kabushiki Kaisha Toshiba
发明人： WATANDO, Hiroko , KUBOKI, Takashi
IPC分类号： B01D15/00 , B01J39/02 , B01D53/14 , B01J20/04 , B01J39/17 , B01J49/06 , B01J49/53 , B01J49/60
CPC分类号： G01N30/96 , B01D15/00 , B01D53/1418 , B01D53/1475 , B01J39/17 , B01J49/06 , B01J49/53 , B01J49/60 , C07C213/10 , C07C241/00 , Y02C10/06 , Y02C10/08 , Y10T436/147777 , Y10T436/170769 , Y10T436/173845
摘要： The objects of embodiments in the present disclosure are to provide a method capable of recovering two or more amine compounds at the same time from a gas or solution, and also to provide a method capable of analyzing the recovered amines. The amine-recovering method comprises the steps (A) and (B). In the step (A), the gas or solution is brought into contact with a solid adsorbent so that the adsorbent may retain the amines. In the step (B), the amines retained by the adsorbent in the step (A) are eluted out by use of a basic compound-containing organic solvent. The solid adsorbent has a substituent group represented by -SO 3 M (M is H or an alkali metal).

2. 发明公开

EP3116488A4 CLOMIPHENE SYNTHESIS USING A SINGLE SOLVENT 审中-公开
公开(公告)号：EP3116488A4
公开(公告)日：2018-04-25
申请号：EP15761286
申请日：2015-03-09
申请人： REPROS THERAPEUTICS INC
发明人： PODOLSKI JOSEPH S , HSU KUANG
IPC分类号： C07C213/08 , C07C51/41 , C07C59/265 , C07C213/10 , C07C217/18
CPC分类号： C07C213/08 , C07B2200/09 , C07C51/412 , C07C59/265 , C07C213/10 , C07C217/18
摘要： The present invention provides a one-pot method for synthesizing clomiphene (a mixture of the isomers cis-clomiphene and trans-clomiphene) utilizing a single solvent. In a preferred embodiment, the single solvent is dichloromethane (DCM, also known as methylene chloride). The present invention provides an improved method for synthesizing clomiphene and purifying clomiphene isomers.

3. 发明公开

EP3201170A1 METHOD OF PRODUCING N-ALKYL POLYAMINES 审中-公开
标题翻译：生产N-烷基多胺的方法
公开(公告)号：EP3201170A1
公开(公告)日：2017-08-09
申请号：EP15759589.3
申请日：2015-08-25
申请人： Curza Global LLC , University of Utah Research Foundation
发明人： LOOPER, Ryan , SEBAHAR, Paul R. , HAUSSENER, Travis
IPC分类号： C07C209/08 , C07C211/14 , C07C211/27 , C07C211/17
CPC分类号： C07C209/08 , C07C209/84 , C07C213/02 , C07C213/10 , C07C2601/14 , C07D317/58 , Y02P20/582 , C07C211/14 , C07C211/27 , C07C211/17
摘要： In one embodiment, the invention presents a process for the preparation of N-alkyl polyamines that includes (i) the conversion of an amino alcohol to an aminoalkyl alkylating agent with a halo or aldehyde reactive group and (ii) the addition of amines to an amine-containing alkylating agent to make an N-alkyl polyamine.
摘要翻译：在一个实施方案中，本发明提供了制备N-烷基多胺的方法，其包括（i）用卤代或醛反应性基团将氨基醇转化为氨基烷基烷基化剂，和（ii）将胺加成到胺包括烷基化剂以制备N-烷基多胺。

4. 发明授权

EP2627627B1 PROCESS FOR THE SYNTHESIS OF CHIRAL PROPARGYLIC ALCOHOLS 失效转让
标题翻译：合成手性普通酒精的方法
公开(公告)号：EP2627627B1
公开(公告)日：2017-08-09
申请号：EP11772888.1
申请日：2011-10-14
申请人： Bristol-Myers Squibb Company
发明人： BRENNER, Meinrad , CARREIRA, Erick, M. , CHINKOV, Nicka , LORENZI, Miriam , WARM, Aleksander , ZIMMERMANN, Lothar
IPC分类号： C07C213/00 , C07B53/00 , C07C213/10 , C07C315/06 , C07D265/18
CPC分类号： C07C315/06 , C07B53/00 , C07C213/00 , C07C213/10 , C07D265/18 , C07C215/68

5. 发明公开

EP3126323A1 MINIMIZING WATER CONTENT IN ETHANOLAMINE PRODUCT STREAMS 有权转让
标题翻译： ETHANOLAMINPRODUKTSTRÖMEN的MINIMIERUNG DES WASSERGEHALTS
公开(公告)号：EP3126323A1
公开(公告)日：2017-02-08
申请号：EP15720463.7
申请日：2015-04-02
申请人： SABIC Global Technologies B.V.
发明人： AL-HAZMI, Naeem
IPC分类号： C07C213/04 , C07C215/08 , C07C213/10
CPC分类号： C07C213/10 , C07C213/04 , C07C215/08 , Y02P20/127
摘要： Systems and method are provided for reducing the water content from approximately 0.15%-0.19% by weight to approximately 0.01-0.03% by weight in an ethanolamine product stream in a non-reactive distillation column. The reduced water content can be achieved by increasing the processing conditions at the drying column by approximately 5% to approximately 20%, more preferably to approximately 10%. The increased processing conditions at the drying column can result in an increased bottom stream flow rate and an increased reboiler duty. The reboiler duty of the drying column can be increased by up to 2% to achieve said level of water content. The bottom stream flow rate can be increased by up to approximately 12% to achieve said level of water content.
摘要翻译：提供的系统和方法用于在非反应性蒸馏塔中的乙醇胺产物流中将水含量从约0.15％-0.19％（重量）降低至约0.01-0.03％（重量）。减少的水含量可以通过将干燥塔处理条件增加约5％至约20％，更优选至约10％来实现。干燥塔处理条件的增加可能导致底部流量增加和再沸器负荷增加。干燥塔的再沸器负荷可以增加高达2％，以达到所述水含量。底部流量可以增加高达约12％，以达到所述含水量。

6. 发明公开

EP3105203A1 STABLE POLYMORPH FORM B OF TAPENTADOL HYDROCHLORIDE 审中-公开
标题翻译：盐酸塔潘特罗的多晶型稳定剂B
公开(公告)号：EP3105203A1
公开(公告)日：2016-12-21
申请号：EP15705246.5
申请日：2015-02-10
申请人： AZAD Pharmaceutical Ingredients AG
发明人： BOCK, Dominique Anna , MAIER, Thomas , HAFERKAMP, Sven , PORSTMANN, Frank
IPC分类号： C07C215/54 , A61K31/135 , A61P13/00
CPC分类号： C07C215/54 , C07B2200/13 , C07C213/10
摘要： The present disclosure relates to Tapentadol Hydrochloride in the polymorphic crystalline Form B, which is substantially free of polymorphic Form A as well as essentially free of low alkyl carboxylic acids or esters of such acids. Furthermore, the present disclosure provides a process to produce this polymorphic Form B substantially free of Form A and its preparation and use for pharmaceutical compositions. This process as well as the specific crystalline form is uncommon, improved and industrially advantageous. Furthermore, the disclosure relates to pharmaceutical compositions and uses thereof.
摘要翻译：本发明涉及呈多晶型结晶形式B的盐酸他喷他多，其基本上不含多晶型形式A，并且基本上不含低级烷基羧酸或此类酸的酯。此外，本发明提供了生产基本上不含形式A的该多晶型B及其制备方法和用于药物组合物的方法。该过程以及特定的结晶形式是不常见的，改进的和工业上有利的。此外，本发明涉及药物组合物及其用途。

7. 发明公开

EP3083551A1 CRYSTALLINE FORMS OF TAPENTADOL INTERMEDIATE 有权转让
标题翻译：结晶形式的TAPENTADOL中间体
公开(公告)号：EP3083551A1
公开(公告)日：2016-10-26
申请号：EP14809628.2
申请日：2014-12-08
申请人： Farma GRS, d.o.o.
发明人： BERGANT SIMONCIC, Ana , KLJAJIC, Alen , SMIRNOVA, Elena
IPC分类号： C07C213/10 , C07C217/62 , C07C215/54
CPC分类号： C07C217/62 , C07C213/10 , C07C215/54
摘要： The present invention pertains to a crystalline and stable form of (βR,γR)-γ-ethyl-N,N,β-trimethyl-3-(phenylmethoxy)benzenepropanamine, as well as to processes for its preparation, and its use in the preparation of tapentadol and pharmaceutically acceptable salts thereof.
摘要翻译：本发明涉及（βR，γR）-γ-乙基-N，N，β-三甲基-3-（苯基甲氧基）苯丙胺的晶体和稳定形式及其制备方法，及其用途在制备他喷他多及其药学上可接受的盐中的用途。

8. 发明公开

EP2909166A4 PROCESSES FOR THE PREPARATION OF AGOMELATINE USING NOVEL INTERMEDIATES 审中-公开
标题翻译：流程，阿戈美拉汀的方法，用新型中间材料
公开(公告)号：EP2909166A4
公开(公告)日：2016-10-26
申请号：EP12887041
申请日：2012-10-22
申请人： SYMED LABS LTD , MOHAN RAO DODDA , ANNA REDDY AMBATI
发明人： MOHAN RAO DODDA , ANNA REDDY AMBATI
IPC分类号： C07C213/02 , C07C213/10 , C07C215/26 , C07C231/02 , C07C233/22 , C07C253/30 , C07C255/36
CPC分类号： C07C213/02 , C07C213/10 , C07C215/26 , C07C231/02 , C07C233/22 , C07C253/30 , C07C255/36

9. 发明公开

EP2646409A4 FINGOLIMOD POLYMORPHS AND THEIR PROCESSES 审中-公开
标题翻译：芬戈莫德多晶型及其方法
公开(公告)号：EP2646409A4
公开(公告)日：2015-12-16
申请号：EP11842990
申请日：2011-08-29
申请人： SHILPA MEDICARE LTD
发明人： SHRAWAT VIMAL KUMAR , VEERESHAPPA , PUROHIT PRASHANT , SINGH VINOD KUMAR
IPC分类号： C07C215/28 , A61K31/137 , A61P37/02 , C07C213/00
CPC分类号： C07C213/10 , C07B2200/13 , C07C215/28

10. 发明公开

EP2831033A4 SYSTEM AND PROCESS FOR RECLAIMING SINGLE AND MIXED AMINE SOLVENTS 有权转让
标题翻译：系统在VERFAHREN ZURRÜCKGEWINNUNGVON EINZELNEN发电机组AMINLÖSUNGEN
公开(公告)号：EP2831033A4
公开(公告)日：2015-11-25
申请号：EP13768394
申请日：2013-03-28
申请人： HTC PURENERGY INC
发明人： ABOUDHEIR AHMED A , ELMOUDIR WALID H
IPC分类号： C07C209/84 , B01D1/00 , B01D53/14 , B01D53/96
CPC分类号： C07C209/84 , B01D1/0064 , B01D1/0082 , B01D1/06 , B01D53/1425 , B01D53/1493 , B01D53/96 , B01D2252/204 , B01D2257/302 , B01D2257/304 , B01D2257/404 , B01D2257/504 , C07C213/10
摘要： A processes is for purifying an amine compound from a feed solvent which includes an amine salt of the amine compound. The process includes heating the feed solvent in a single stage evaporator of a reclaimer at a reduced operating pressure by feeding the evaporator with a constant amount of thermal energy; and evaporating the amine compound to purity the amine compound from the feed solvent.
摘要翻译：一种方法是从包括胺化合物的胺盐的进料溶剂中纯化胺化合物。该方法包括通过以恒定量的热能供给蒸发器，在降低的操作压力下在回收机的单级蒸发器中加热进料溶剂; 并蒸发胺化合物以纯化来自进料溶剂的胺化合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式