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3. 发明公开

EP3352882A1 MULTI-USE ACOUSTIC LEVITATION TRAP 有权
公开(公告)号：EP3352882A1
公开(公告)日：2018-08-01
申请号：EP16777602.0
申请日：2016-09-23
申请人： Aenitis Technologies
发明人： VINCENT, Emmanuel , BOHEC, Pierre
IPC分类号： B01D43/00 , B01L3/00 , B01D49/00 , B01D51/08
CPC分类号： B01D43/00 , B01D21/283 , B01D51/08 , B01L3/502761 , B01L2200/0668 , B01L2400/0439 , G01N15/1056 , G01N15/1404 , G01N2015/0038 , G01N2015/1081 , G01N2015/142 , G01N2015/149
摘要： Disclosed is a device, suitable for use as an acoustic resonator, including a base adapted to be coupled to at least one acoustic wave generator, a spacer including an aperture and a reflector, wherein the base includes a protruding part having a thickness t; the aperture of the spacer is complementary to the protruding part of the base; the device further includes a housing having an aperture complementary to the protruding part of the base and wherein the inner edge of the aperture has the same thickness t than the protruding part; and the housing is positioned between the spacer and the reflector, such that the thickness of the inner edge of the spacer defined the thickness of a cavity between the protruding part and the reflector. Also disclosed is a method of trapping particles in a fluid.

4. 发明公开

EP3341102A1 LARGE SCALE ACOUSTIC SEPARATION DEVICE 审中-公开
公开(公告)号：EP3341102A1
公开(公告)日：2018-07-04
申请号：EP16770116.8
申请日：2016-08-26
申请人： Flodesign Sonics Inc.
发明人： LIPKENS, Bart , PRESZ JR, Walter M. , KING, Jeffrey , BARNES, Jason , MEALEY, Dane , MCCARTHY, Brian , ROSS-JOHNSRUD, Benjamin , CHITALE, Kedar
IPC分类号： B01D21/28 , C02F1/36 , B06B1/06 , G01N33/15 , A61M1/36
CPC分类号： B01D21/283 , A61M1/3678 , B06B1/0622 , G10K11/28 , G10K11/34 , G10K15/00
摘要： Devices (100) for separating a host fluid from a second fluid or particulate are disclosed. The devices include an acoustic chamber (107), a fluid outlet at a top end of the acoustic chamber (114), a concentrate outlet at a bottom end of the acoustic chamber (116), and an inlet (112) on a first side end (122) of the acoustic chamber (107). An ultrasonic transducer (106) on a side wall of the acoustic chamber and reflector at the opposite side wall create a multi-dimensional acoustic standing wave in the acoustic chamber (107) that traps and separates particulates (e.g. cells) from a host fluid. The host fluid is collected via the fluid outlet (114), and the particulates are collected via the concentrate outlet (116). The device is a large-scale device that is able to process liters/hour, and has a large interior volume.

5. 发明公开

EP3164488A4 ACOUSTOPHORETIC DEVICE WITH UNIFORM FLUID FLOW 有权
公开(公告)号：EP3164488A4
公开(公告)日：2018-04-11
申请号：EP15814616
申请日：2015-07-02
申请人： FLODESIGN SONICS INC
发明人： LIPKENS BART , MCCARTHY BRIAN , BARNES JASON , MEALEY DANE , ROSS JOHNSRUD BEN , PRESZ JR WALTER M , CHITALE KEDAR
IPC分类号： A61M1/36 , B01D21/00 , B01D21/28 , B06B1/06 , C12M1/00 , C12M1/26
CPC分类号： B01D21/283 , B01D21/0045
摘要： An acoustophoresis device which includes a substantially vertical flow path of the fluid mixture in order to improve separation of particles/secondary fluid from a primary fluid is disclosed. The vertical flow path reduces velocity non-uniformities in the acoustic chamber resulting from gravity forces. The device includes an acoustic chamber in which multidimensional acoustic standing waves are generated. The fluid can be introduced into the acoustic chamber using a dump diffuser in which a plurality of inlets enter near the bottom of the acoustic chamber such that flow symmetry reduces both, gravity driven flow non-uniformities, and any flow interference effects between inlet mixture flow into the acoustic chamber and the continuous gravity driven particle cluster drop out.

6. 发明公开

EP3288660A1 ACOUSTOPHORETIC DEVICE FOR ANGLED WAVE PARTICLE DEFLECTION 审中-实审转让
公开(公告)号：EP3288660A1
公开(公告)日：2018-03-07
申请号：EP16732365.8
申请日：2016-04-29
申请人： Flodesign Sonics Inc.
发明人： LIPKENS, Bart , PRESZ, Walter M. Jr. , CHITALE, Kedar , KENNEDY, Thomas J. III , ROSS-JOHNSRUD, Ben
IPC分类号： B01D21/28 , B01J19/10 , A61M1/36
CPC分类号： C12N13/00 , A61M1/3678 , B01D21/283 , B01L3/502761 , B01L2300/0864 , B01L2300/0867 , B01L2400/0436 , B01L2400/0439 , C12M47/04 , G01N15/1484 , G01N2015/0053 , G01N2015/1006 , G01N2015/149
摘要： Devices for separating materials from a host fluid are disclosed. The devices include a flow chamber, an ultrasonic transducer, and a reflector. The ultrasonic transducer and reflector create an angled acoustic standing wave oriented at an angle relative to the direction of mean flow through the flow chamber. The angled acoustic standing wave results in an acoustic radiation force having an axial force component that deflects the materials, so that the materials and the host fluid can thus be separated. The angled acoustic standing wave can be oriented at an angle of about 20° to about 70° relative to the direction of mean flow through the flow chamber to deflect, collect, differentiate, or fractionate the materials from the fluid flowing through the device at flow rates of about 400 mL/min up to about 700 mL/min.

7. 发明公开

EP3126028A1 A REFLECTOR FOR AN ACOUSTOPHORETIC DEVICE 审中-公开
标题翻译： REFERKTORFÜREINE AKUSTOPHORETISCHE VORRICHTUNG
公开(公告)号：EP3126028A1
公开(公告)日：2017-02-08
申请号：EP15733002.8
申请日：2015-04-03
申请人： Flodesign Sonics Inc.
发明人： MCCARTHY, Brian , ROSS-JOHNSRUD, Ben , LIPKENS, Bart
IPC分类号： B01D21/28 , B01D49/00 , B06B1/06
CPC分类号： B06B1/0644 , B01D21/283 , G10K11/20
摘要： An apparatus includes a flow chamber having at least one inlet and at least one outlet. At least one ultrasonic transducer is located on a wall of the flow chamber, which operates to create a multi-dimensional acoustic standing wave in the flow chamber. A reflector is located on the wall on the opposite side of the flow chamber from the at least one ultrasonic transducer. The reflector is formed from a thin structure that provides a pressure release boundary, such as a plastic film/air interface.
摘要翻译：一种装置包括具有至少一个入口和至少一个出口的流动室。至少一个超声换能器位于流动室的壁上，其操作以在流动室中产生多维声驻波。反射器位于流动室的与至少一个超声波换能器相反的一侧的壁上。反射器由提供压力释放边界的薄结构形成，例如塑料膜/空气界面。

8. 发明公开

EP3065795A1 ACOUSTOPHORESIS DEVICE WITH MODULAR COMPONENTS 审中-公开
标题翻译： AKUSTOPHORESEVORRICHTUNG MIT MODULAREN KOMPONENTEN
公开(公告)号：EP3065795A1
公开(公告)日：2016-09-14
申请号：EP14812011.6
申请日：2014-11-05
申请人： Flodesign Sonics Inc.
发明人： LIPKENS, Bart , BARNES, Jason , MEALEY, Dane , PRESZ, Walter M. Jr , KOWALSKI, Stanley, III , MASI, Louis , KENNEDY, Thomas J., III , MCCARTHY, Brian , ROSS-JOHNSRUD, Ben
IPC分类号： A61M1/36 , C12M1/26 , C12M1/00 , B60B1/00
CPC分类号： C12M47/02 , A61M1/3678 , B01D21/0045 , B01D21/283 , B06B1/06 , C12M33/08 , C12M47/10
摘要： An acoustophoresis device made up of modular components is disclosed. Several modules are disclosed herein, including ultrasonic transducer modules, input/output modules, collection well modules, and various connector modules. These permit different systems to be constructed that have appropriate fluid dynamics for separation of particles, such as biological cells, from a fluid.
摘要翻译：公开了一种由模块化部件组成的消声装置。本文公开了多个模块，包括超声换能器模块，输入/输出模块，收集井模块和各种连接器模块。这些允许构建具有用于从流体分离颗粒（例如生物细胞）的适当流体动力学的不同系统。

9. 发明公开

EP3060905A1 VIRTUAL DETERMINISTIC LATERAL DISPLACEMENT FOR PARTICLE SEPARATION USING SURFACE ACOUSTIC WAVES 审中-公开
标题翻译： VIRTUELLE DETERMINISTISCHE QUERVERSCHIEBUNG ZUR TEILCHENSEPARATION MITHILFE VONOBERFLÄCHENSCHALLWELLEN
公开(公告)号：EP3060905A1
公开(公告)日：2016-08-31
申请号：EP14855272.2
申请日：2014-10-27
申请人： Monash University
发明人： NEILD, Adrian , ALAN, Tuncay , COLLINS, David John
IPC分类号： G01N29/02
CPC分类号： B01L3/502715 , B01D21/283 , B01L3/50273 , B01L3/502761 , B01L2200/0652 , B01L2300/06 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2400/0424 , B01L2400/0433 , B01L2400/0436 , B01L2400/0496 , B03C5/005 , B03C5/026 , B03C2201/26 , G01N15/0255 , G01N15/1031 , G01N15/1056 , G01N27/4473 , G01N27/44791 , G01N2001/4038 , G01N2015/0288 , G01N2015/1081
摘要： A microfluidic device for separating or sorting particles in a fluid including: a substrate; a plurality of interdigital transducers on the substrate; a microfluidic channel adapted to have fluid flow within, located over the interdigital transducers, the microfluidic channel having a width, wherein: the interdigital transducers are located within the width of the microfluidic channel; and application of a signal to the interdigital transducers produces a force field at an angle to the fluid flow direction within the microfluidic channel. In addition, a method for separating or sorting particles using a device having a plurality of interdigital transducers on a substrate and a microfluidic channel located over the interdigital transducers, the method including: positioning the interdigital transducers within the microfluidic channel width; inserting into the microfluidic channel a solution having particles with various properties; and applying a signal to the interdigital transducers to produce a force field at an angle to a fluid flow direction within the microfluidic channel to sort and/or physically separate the particles into groups of particles with the same property.
摘要翻译：一种用于分离或分选流体中的颗粒的微流体装置，包括：基底; 在所述基板上的多个叉指换能器; 微流体通道，其适于在所述叉指式换能器之间具有流体流动，所述微流体通道具有宽度，其中：所述叉指换能器位于所述微流体通道的宽度内; 并且将信号施加到叉指换能器产生与微流体通道内的流体流动方向成一定角度的力场。另外，使用在衬底上具有多个叉指式换能器的装置和位于叉指式换能器上方的微流体通道来分离或分选颗粒的方法，所述方法包括：将所述叉指式换能器定位在所述微流体通道宽度内; 将具有各种性质的颗粒的溶液插入到微流体通道中; 并且将信号施加到叉指式换能器以产生与微流体通道内的流体流动方向成一定角度的力场，以将颗粒排列和/或物理地分离成具有相同性质的颗粒组。

10. 发明公开

EP2974777A1 VIBRATING-TYPE, TILTED PLATE BOX SETTLING SEPARATOR 有权
标题翻译：基因印度尼西亚麻醉药物EINER VIBRIERENDEN，GENEIGTEN PLATTE
公开(公告)号：EP2974777A1
公开(公告)日：2016-01-20
申请号：EP13877591.1
申请日：2013-06-05
申请人： Kunming University Of Science And Technology , Zhou, Xinglong
发明人： ZHOU, Xinglong
IPC分类号： B01D21/02 , B01D21/28
CPC分类号： B01D21/283 , B01D21/0003 , B01D21/0039 , B01D21/0045 , B01D21/0069 , B01D21/01 , B01D21/02 , B01D21/2405 , B01D21/2444 , B01D21/245 , B01D2221/04
摘要： The invention involves a vibrating inclined plate box settlement separator, which is used for the liquid-solid separation, particularly applicable to high-efficiency settling concentration and separation of solid particles from liquid or water. The separator consists of an upper box and a lower tapered hopper. The upper box and the lower tapered hopper are connected securely to each other and sealed. The upper box is a rectangular or square steel-structured box with two supporting platforms on both of its sides, on which several spring assemblies are installed. The inclined plate box modules which can independently vibrate are installed on the spring assemblies. The feed box is placed on top of or inside the upper box. An overflow collect chute is welded on the side of the box frame opposite to the feed box. The inclined plate box modules are connected to the overflow collect chute with rubber tubes. The lower tapered hopper is a square or rectangular square tapered hopper or a square round tapered hopper. It is mounted securely onto steel-structured bracket or reinforced concrete framework. A smaller wear-resistant tapered hopper is connected to the bottom of the first hopper.
摘要翻译：本发明涉及用于液固分离的振动倾斜板箱沉降分离器，特别适用于固体颗粒与液体或水的高效沉降浓度和分离。分离器由上部箱体和下部锥形料斗组成。上盒和下锥形料斗彼此牢固地连接并密封。上部箱体是矩形或方形钢结构的箱体，其两侧具有两个支撑平台，其上安装有几个弹簧组件。可以独立振动的倾斜板箱模块安装在弹簧组件上。送料盒放置在上部盒子的上方或内部。溢流收集滑槽焊接在与进料盒相对的箱体框架的侧面。倾斜板箱模块用橡胶管连接到溢流集水槽。下锥形料斗是方形或矩形方形锥形料斗或方圆锥形料斗。它牢固地安装在钢结构支架或钢筋混凝土框架上。较小的耐磨锥形料斗连接到第一料斗的底部。

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