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1. 发明授权

EP3126001B1 IMAGE-GUIDED RADIATION THERAPY 有权
公开(公告)号：EP3126001B1
公开(公告)日：2018-12-12
申请号：EP15713908.0
申请日：2015-04-07
申请人： Elekta AB (PUBL)
发明人： KONTAXIS, Charis , BOL, Gijsbert Herman , RAAYMAKERS, Bas Willem
IPC分类号： A61N5/10
CPC分类号： A61N5/1067 , A61N5/1031 , A61N5/1037 , A61N5/1038 , A61N5/1039 , A61N5/1047 , A61N5/1049 , A61N5/1071 , A61N2005/1034 , A61N2005/1054 , A61N2005/1055 , A61N2005/1058
摘要： The disclosed systems and methods for Image-Guided Radiation Therapy (IGRT), utilises an iterative approach which adjusts a treatment plan based on inter- or intra-fraction images to improve the accuracy of the radiation delivered during the overall treatment. The prescribed dose of radiotherapeutic radiation is mapped onto the patient's anatomy using an image acquired of the region, which is to be the target for radiotherapeutic radiation. Following beam-angle-optimisation, fluence optimisation and segmentation, the efficiency of delivery of each segment is determined using an objective function, and the segments ranked according to their efficiency. The plan proceeds with the choice of the most efficient segment (or segments) to be delivered first. When this radiation has been delivered, having been tracked to establish its distribution, this delivered distribution can be subtracted from the original prescribed dose and the process repeated so that the delivered radiation gradually converges on the original prescribed dose.

2. 发明授权

EP3302701B1 RADIATION THERAPY OPTIMIZATION UNIT WITH GLOBAL CONSIDERATIONS 有权
公开(公告)号：EP3302701B1
公开(公告)日：2018-11-28
申请号：EP16725604.9
申请日：2016-05-23
申请人： Koninklijke Philips N.V.
发明人： BZDUSEK, Karl Antonin , KUMAR, Prashant
IPC分类号： A61N5/10
CPC分类号： A61N5/1031 , A61N5/1039 , A61N5/1047 , A61N5/1077
摘要： A radiation therapy planning system (100) includes a radiation therapy optimization unit (124), which receives at least one target structure and at least one organ-at-risk (OAR) structure segmented from a volumetric image, and generates an optimized plan (126) based on at least one modified objective function. The optimized plan (126) includes a planned radiation dose for each voxel.

3. 发明公开

EP3169399A4 SYSTEMS AND METHODS FOR PROVIDING RADIOTHERAPY TREATMENT 有权
公开(公告)号：EP3169399A4
公开(公告)日：2018-03-14
申请号：EP15822567
申请日：2015-07-16
申请人： THE UAB RES FOUNDATION
发明人： POPPLE RICHARD
IPC分类号： A61N5/01
CPC分类号： A61N5/1047 , A61N5/1039 , A61N5/1045 , A61N5/1081
摘要： In one embodiment, radiotherapy treatment is provided to a target volume of a patient by configuring a multileaf collimator of a radiation treatment machine in a first orientation so as to form an actual aperture having a first orientation, delivering radiation to the target volume through the actual aperture while in the first orientation with a single pass along an arcuate path centered on the target volume, configuring the multileaf collimator in a second orientation so as to place the actual aperture in a second orientation that is different from the first orientation, and delivering radiation to the target volume through the actual aperture while in the second orientation with a single pass back along the arcuate path such that a relatively large cumulative dose of radiation is delivered to the target volume through a virtual aperture created by an area of overlap between the first and second actual aperture orientations.

4. 发明公开

EP2280765A4 TREATMENT OF PATIENT TUMORS BY CHARGED PARTICLE THERAPY 有权
标题翻译： BEHANDLUNG VON PATIENTENTUMOREN DURCH EINE THERAPIE MIT GELADENEN PARTIKELN
公开(公告)号：EP2280765A4
公开(公告)日：2017-09-27
申请号：EP09767270
申请日：2009-05-26
申请人： VARIAN MED SYS INC
发明人： BOEH LESTER , CLAYTON JAMES , MARC MARCEL , LANGENEGGER ARMIN
IPC分类号： A61N5/10 , A61N1/00
CPC分类号： A61N5/1042 , A61N5/1047 , A61N2005/1087

5. 发明授权

EP2792388B1 Bestrahlungseinrichtung 有权转让
标题翻译：照射装置
公开(公告)号：EP2792388B1
公开(公告)日：2017-09-20
申请号：EP13002067.0
申请日：2013-04-19
申请人： Scientific RT GmbH
发明人： Sobotta, Benjamin , Alber, Markus
IPC分类号： A61N5/10
CPC分类号： A61N5/103 , A61N5/1036 , A61N5/1042 , A61N5/1047 , A61N5/1081 , A61N2005/1091 , H05K999/00

6. 发明授权

EP2983782B1 ISODOSE OPTIMIZATION 有权
公开(公告)号：EP2983782B1
公开(公告)日：2017-08-30
申请号：EP14720258.4
申请日：2014-04-03
申请人： Koninklijke Philips N.V.
发明人： BZDUSEK, Karl, Antonin , FRIGO, Sean
IPC分类号： A61N5/10
CPC分类号： A61N5/1031 , A61N5/1047 , A61N2005/1074

7. 发明公开

EP3157628A1 SYSTEM AND COMPUTER PROGRAM PRODUCT FOR INVERSE TREATMENT PLANNING. 有权
标题翻译：系统计算机计算机系统。
公开(公告)号：EP3157628A1
公开(公告)日：2017-04-26
申请号：EP15731534.2
申请日：2015-06-11
申请人： Intuitive Therapeutics SA
发明人： MARTIN, André , SALZMANN, Daniel
IPC分类号： A61N5/10
CPC分类号： A61N5/1031 , A61B6/5294 , A61B6/54 , A61N5/103 , A61N5/1038 , A61N5/1042 , A61N5/1047 , A61N5/1071 , A61N5/1075 , G01T1/2914 , G05B2219/33079 , G06F17/16 , G06F17/30271
摘要： The present invention concerns an inverse treatment planning system. The system includes, at least a data bus system (102), a memory (106) coupled to the data bus system (102), and a processing unit (104) coupled to the data bus system (102). The processing unit (104) is configured to execute the instructions to pre-compute (10) a set of individual dose shots (aj), each individual dose shot having a predetermined location inside and/or outside a target area, a size and a shape. The processing unit also associates (40) a weight (sj) to each individual dose shot (aj), based on one or more constraints (20). The processing unit (104) further executes the instructions to find (30) the sparsest subset of individual dose shots, so as to satisfy said one or more constraints (20).
摘要翻译：本发明涉及一种用于线性加速器的辐射反向治疗计划系统，包括：辐射源，其被配置用于传送各个剂量射击（aj），每个单独的剂量射击在目标区域内部和/或外部具有预定位置和入射角至少数据总线系统（102）的大小和形状，耦合到数据总线系统（102）的存储器（106），其中存储器（106）包括计算机可用程序代码，以及处理单元（104））耦合到所述数据总线系统（102），其中所述处理单元（104）被配置为执行所述计算机可用程序代码以预先计算（10）一组单独剂量镜头（aj），所述联合（40）重量（20），其特征在于，所述处理单元（104）执行所述计算机可用程序代码以找到（30）所述单个剂量镜头的最小子集，以便满足所述一个或多个约束（20）。

8. 发明公开

EP3064252A1 MULTIPURPOSE RADIOTHERAPY SYSTEM 有权转让
标题翻译：多功能辐射治疗系统
公开(公告)号：EP3064252A1
公开(公告)日：2016-09-07
申请号：EP13896320.2
申请日：2013-11-01
申请人： Cybermed Technologies (xi'an) Co., Ltd.
发明人： LIU, Haifeng
IPC分类号： A61N5/10
CPC分类号： A61N5/1081 , A61N5/1039 , A61N5/1042 , A61N5/1047 , A61N5/1082 , A61N5/1084
摘要： The present invention relates to a multi-purpose radiation therapy system. The radiation therapy system comprises a base, a movable couch, a rotatable gantry, and a radiotherapeutic apparatus. The movable couch and the rotatable gantry are arranged on the base, while the movable couch is sleeved in the rotatable gantry, and the radiotherapeutic apparatus is movably installed on the rotatable gantry. The radiotherapeutic apparatus includes a multi-source focusing radiotherapeutic unit and an adaptive intensity modulated radiotherapeutic unit. The multi-source focusing radiotherapeutic unit and the adaptive intensity modulated radiotherapeutic unit are distributed at both sides of a rotatable gantry axis, and are connected to the rotatable gantry via respective arc guide rail.

9. 发明授权

EP2200698B1 METHOD AND APPARATUS FOR INTENSITY MODULATED ARC THERAPY SEQUENCING AND OPTIMIZATION 有权转让
标题翻译：测序和旋转治疗强度的优化方法和装置调制式
公开(公告)号：EP2200698B1
公开(公告)日：2011-05-18
申请号：EP08840706.9
申请日：2008-10-02
申请人： Koninklijke Philips Electronics N.V.
发明人： BZDUSEK, Karl, Antonin
IPC分类号： A61N5/10
CPC分类号： A61N5/1042 , A61N5/103 , A61N5/1047
摘要： A treatment planner (102) generates fluence maps (140) indicative of a desired fluence distribution at various locations (304, 312) along a treatment arc (302). A converter (142) converts the fluence distributions (140) to treatment device settings (144). The settings (144) may include multiple segments. A segment distributor (146) distributes the settings to locations in the vicinity of their original positions.

10. 发明授权

EP3157628B1 SYSTEM AND COMPUTER PROGRAM PRODUCT FOR INVERSE TREATMENT PLANNING. 有权
公开(公告)号：EP3157628B1
公开(公告)日：2018-10-31
申请号：EP15731534.2
申请日：2015-06-11
申请人： Intuitive Therapeutics SA
发明人： MARTIN, André , SALZMANN, Daniel
IPC分类号： A61N5/10
CPC分类号： A61N5/1031 , A61B6/5294 , A61B6/54 , A61N5/103 , A61N5/1038 , A61N5/1042 , A61N5/1047 , A61N5/1071 , A61N5/1075 , G01T1/2914 , G05B2219/33079 , G06F17/16 , G06F17/30271
摘要： The present invention concerns an inverse treatment planning system. The system includes, at least a data bus system (102), a memory (106) coupled to the data bus system (102), and a processing unit (104) coupled to the data bus system (102). The processing unit (104) is configured to execute the instructions to pre-compute (10) a set of individual dose shots (aj), each individual dose shot having a predetermined location inside and/or outside a target area, a size and a shape. The processing unit also associates (40) a weight (sj) to each individual dose shot (aj), based on one or more constraints (20). The processing unit (104) further executes the instructions to find (30) the sparsest subset of individual dose shots, so as to satisfy said one or more constraints (20).

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