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1. 发明公开

EP1731162A2 Apparatus, method and compositions for the treatment of cancers by ultraphoresis 审中-公开
标题翻译：设备，方法和组合物用于治疗癌症的用血液超
公开(公告)号：EP1731162A2
公开(公告)日：2006-12-13
申请号：EP06076477.6
申请日：1999-05-21
申请人： BioPheresis Technologies, Inc.
发明人： Lentz, M. Rigdon
IPC分类号： A61K38/19 , B01D61/00 , A61P35/00 , A61P33/00 , A61P37/00
CPC分类号： A61K35/14 , A61K31/00 , A61K31/337 , A61K31/454 , A61K31/555 , A61K31/704 , A61K35/16 , A61K38/18 , A61K38/1816 , A61K38/193 , A61K38/196 , A61K41/00 , A61K41/0019 , A61M1/34 , A61M1/342 , A61M1/3441 , A61M1/3472 , A61M1/3482 , A61M1/3681 , A61M2202/0417 , A61M2205/50 , A61M2205/75 , A61N5/1028 , B01D15/00 , B01D29/50 , B01D37/00 , B01D61/02 , A61K2300/00
摘要： Apparatus for treating a patient, comprising a sterile device for removing soluble receptors for tumor necrosis factor-1 (TNF-1), tumor necrosis factor-2 (TNF-2), interleukin-1 (IL-1), interleukin-2 (IL-2), interleukin-6 (IL-6) or interferon-gamma (IFN-γ) from blood or plasma of a patient, and having inlet and outlet means for connection to a pump and tubing to circulate the blood or plasma through the device. Preferably the device comprises antibodies or antibody fragments that selectively bind to the soluble receptors, or cytokines selected from TNF-1, TNF-2, IL-1, IL-2, IL-6 and IFN-γ or epitopes thereof that selectively bind to the respective soluble receptors, immobilized on a column or a filter.

2. 发明公开

EP2614857A4 METHOD AND DEVICE FOR PREVENTION OR TREATMENT OF ATOPIC DERMATITIS 有权转让
标题翻译：方法和装置用于预防或治疗过敏性湿疹
公开(公告)号：EP2614857A4
公开(公告)日：2014-01-29
申请号：EP11823356
申请日：2011-07-29
申请人： SHARP KK
发明人： OKANO HIROAKI
IPC分类号： A61N1/44 , B62B9/10 , B62B9/14 , H01T23/00
CPC分类号： A61N5/1028 , A61L2/14 , A61N1/44 , B62B9/00 , B62B9/14 , H01T23/00
摘要： A method for preventing or treating atopic dermatitis of a patient by covering the patient itself or a patient's area affected by the atopic dermatitis, filling a covered space with positive ions composed of H + (H 2 O) m (m being any integer) and negative ions composed of O 2 - (H 2 O) n (n being any integer) generated as a result of discharge in an atmosphere, and bringing the positive ions and the negative ions into contact with a skin surface of the patient and a medical device for preventing or treating atopic dermatitis by covering a patient itself or an affected area, filling a covered space with positive ions composed of H + (H 2 O) m (m being any integer) and negative ions composed of O 2 - (H 2 O) n (n being any integer) generated as a result of discharge in an atmosphere, and bringing the positive ions and the negative ions into contact with a skin surface of the patient.

3. 发明授权

EP1079875B1 CANCER TREATMENT BY ULTRAPHERESIS REMOVING COMPOUNDS OF LESS THAN 120,000 DALTONS 有权
标题翻译：癌症治疗BY ultrapheresed拆除化合物120 000道尔顿
公开(公告)号：EP1079875B1
公开(公告)日：2006-09-20
申请号：EP99928331.0
申请日：1999-05-21
申请人： BioPheresis Technologies, Inc.
发明人： Lentz, M. Rigdon
IPC分类号： A61M1/34 , A61K31/445 , A61K38/19 , A61K38/17
CPC分类号： A61K35/14 , A61K31/00 , A61K31/337 , A61K31/454 , A61K31/555 , A61K31/704 , A61K35/16 , A61K38/18 , A61K38/1816 , A61K38/193 , A61K38/196 , A61K41/00 , A61K41/0019 , A61M1/34 , A61M1/342 , A61M1/3441 , A61M1/3472 , A61M1/3482 , A61M1/3681 , A61M2202/0417 , A61M2205/50 , A61M2205/75 , A61N5/1028 , B01D15/00 , B01D29/50 , B01D37/00 , B01D61/02 , A61K2300/00
摘要： Apparatus for treating a patient, comprising a sterile device for removing soluble receptors for tumor necrosis factor-1 (TNF-1), tumor necrosis factor-2 (TNF-2), interleukin-1 (IL-1), interleukin-2 (IL-2), interleukin-6 (IL-6) or interferon-gamma (IFN-³) from blood or plasma of a patient, and having inlet and outlet means for connection to a pump and tubing to circulate the blood or plasma through the device. Preferably the device comprises antibodies or antibody fragments that selectively bind to the soluble receptors, or cytokines selected from TNF-1, TNF-2, IL-1, IL-2, IL-6 and IFN-³ or epitopes thereof that selectively bind to the respective soluble receptors, immobilized on a column or a filter.

4. 发明公开

EP2569053A1 METHOD OF GENERATING AND/OR PROVIDING DATA FOR TISSUE TREATMENT 有权
标题翻译：方法产生和/或提供数据对织物处理
公开(公告)号：EP2569053A1
公开(公告)日：2013-03-20
申请号：EP11718414.3
申请日：2011-05-10
申请人： Carl Zeiss Meditec AG
发明人： WEIGAND, Frank , HERSKIND, Carsten , WENZ, Frederik
IPC分类号： A61N5/10
CPC分类号： A61N5/1031 , A61N5/1001 , A61N5/1015 , A61N5/1028
摘要： A method of generating and/or providing data (28) for tissue treatment, in particular a tumor treatment, via a low-energy irradiation appliance (10) is described. Herein, the low-energy irradiation appliance (10) has a radiation source (14) for generating soft radiation, preferably of a radiation with a spectrum from 0 to a maximal radiation energy of 100 keV, in particular a radiation with a spectrum from 0 to a maximal radiation energy of 50 keV and an emitting device (15) for emitting the radiation to tissue, which is to be irradiated. The method is characterized by the following steps: physical data of the radiation source (14) is determined directly from leaving the emitting device (15); quality data of the tissue, for example the tumor tissue and/or the tissue (17) in the vicinity of the tumor, is determined; physical property data of the determined tissue is determined in connection with the radiation of the radiation source (14). Data (28) for the tissue treatment, for example the tumor treatment, is generated from the determined data and/or the determined data is provided for generating data for the tissue treatment, in particular tumor treatment.

5. 发明公开

EP2335777A2 Applikatoreinrichtung für die Röntgenstrahlentherapie, Befestigungseinrichtung sowie Strahlentherapievorrichtung 有权转让
标题翻译： ApplikatoreinrichtungfürdieRöntgenstrahlentherapiesowie Strahlentherapievorrichtung
公开(公告)号：EP2335777A2
公开(公告)日：2011-06-22
申请号：EP10194113.6
申请日：2010-12-08
申请人： Carl Zeiss Surgical GmbH
发明人： Kleinwächter, Timo , Weigand, Frank, Dr. , Wenz, Frederik, Prof. Dr.
IPC分类号： A61N5/10
CPC分类号： A61N5/1028 , A61N5/1014 , A61N2005/1096
摘要： Es werden unter anderem eine Applikatoreinrichtung (20) für die Röntgenstrahlentherapie zur Bestrahlung von Oberflächen, sowie eine Strahlentherapievorrichtung beschrieben, mit einem Applikatorelement (21) zur Aufnahme einer Sondeneinrichtung oder eines Strahlungsquellenelements einer Strahlungsquelleneinrichtung (11). Um die Applikatoreinrichtung (20) derart weiterzubilden, dass diese in besonderer Weise auch für die Bestrahlung von Oberflächen geeignet ist, ist vorgesehen, dass das Applikatorelement (21) zur Einstellung verschiedener Strahlcharakteristika wenigstens ein austauschbar am/im Applikatorelement (21) angeordnetes Element (27) zur Strahlbeeinflussung, insbesondere ein Linsenelement, aufweist. Weiterhin wird eine vorteilhafte Befestigungseinrichtung beschrieben, mittels derer die Applikatoreinrichtung (20) auf der zu behandelnden Oberfläche befestigt und fixiert werden kann.
摘要翻译：装置（20）具有用于容纳探针装置（12）或辐射源装置（11）的施加器元件（21）。施用器元件包括元件例如透镜元件（27）或透镜元件组合，用于影响辐射以调节不同的辐射特性，其中透镜元件可更换地布置在施加器元件和/或施加器元件中。透镜元件或透镜元件组合在横向于传播方向X射线的平面中形成为具有不同的质量分布。施用器元件是圆柱形的。还包括用于放射治疗装置的独立权利要求，该放射治疗装置包括应用装置和紧固装置，用于将X射线治疗的施用装置紧固在待治疗的表面上。

6. 发明授权

EP2569053B1 METHOD OF GENERATING AND/OR PROVIDING DATA FOR TISSUE TREATMENT 有权
公开(公告)号：EP2569053B1
公开(公告)日：2018-11-14
申请号：EP11718414.3
申请日：2011-05-10
申请人： Carl Zeiss Meditec AG
发明人： WEIGAND, Frank , HERSKIND, Carsten , WENZ, Frederik
IPC分类号： A61N5/10
CPC分类号： A61N5/1031 , A61N5/1001 , A61N5/1015 , A61N5/1028
摘要： A method of generating and/or providing data (28) for tissue treatment, in particular a tumor treatment, via a low-energy irradiation appliance (10) is described. Herein, the low-energy irradiation appliance (10) has a radiation source (14) for generating soft radiation, preferably of a radiation with a spectrum from 0 to a maximal radiation energy of 100 keV, in particular a radiation with a spectrum from 0 to a maximal radiation energy of 50 keV and an emitting device (15) for emitting the radiation to tissue, which is to be irradiated. The method is characterized by the following steps: physical data of the radiation source (14) is determined directly from leaving the emitting device (15); quality data of the tissue, for example the tumor tissue and/or the tissue (17) in the vicinity of the tumor, is determined; physical property data of the determined tissue is determined in connection with the radiation of the radiation source (14). Data (28) for the tissue treatment, for example the tumor treatment, is generated from the determined data and/or the determined data is provided for generating data for the tissue treatment, in particular tumor treatment.

7. 发明公开

EP2335777A3 Applikatoreinrichtung für die Röntgenstrahlentherapie, Befestigungseinrichtung sowie Strahlentherapievorrichtung 有权转让
标题翻译：涂抹器用于X射线辐射，紧固装置以及放射线治疗装置
公开(公告)号：EP2335777A3
公开(公告)日：2011-08-17
申请号：EP10194113.6
申请日：2010-12-08
申请人： Carl Zeiss Surgical GmbH
发明人： Kleinwächter, Timo , Weigand, Frank, Dr. , Wenz, Frederik, Prof. Dr.
IPC分类号： A61N5/10
CPC分类号： A61N5/1028 , A61N5/1014 , A61N2005/1096
摘要： Es werden unter anderem eine Applikatoreinrichtung (20) für die Röntgenstrahlentherapie zur Bestrahlung von Oberflächen, sowie eine Strahlentherapievorrichtung beschrieben, mit einem Applikatorelement (21) zur Aufnahme einer Sondeneinrichtung oder eines Strahlungsquellenelements einer Strahlungsquelleneinrichtung (11). Um die Applikatoreinrichtung (20) derart weiterzubilden, dass diese in besonderer Weise auch für die Bestrahlung von Oberflächen geeignet ist, ist vorgesehen, dass das Applikatorelement (21) zur Einstellung verschiedener Strahlcharakteristika wenigstens ein austauschbar am/im Applikatorelement (21) angeordnetes Element (27) zur Strahlbeeinflussung, insbesondere ein Linsenelement, aufweist. Weiterhin wird eine vorteilhafte Befestigungseinrichtung beschrieben, mittels derer die Applikatoreinrichtung (20) auf der zu behandelnden Oberfläche befestigt und fixiert werden kann.

8. 发明公开

EP1731162A3 Apparatus, method and compositions for the treatment of cancers by ultraphoresis 审中-公开
标题翻译： Apparat，Methode und Zusammensetzungen zur Krebsbehandlung mittels Ultrapherese
公开(公告)号：EP1731162A3
公开(公告)日：2007-02-28
申请号：EP06076477.6
申请日：1999-05-21
申请人： BioPheresis Technologies, Inc.
发明人： Lentz, M. Rigdon
IPC分类号： A61K38/19 , B01D61/00 , A61P35/00 , A61P33/00 , A61P37/00
CPC分类号： A61K35/14 , A61K31/00 , A61K31/337 , A61K31/454 , A61K31/555 , A61K31/704 , A61K35/16 , A61K38/18 , A61K38/1816 , A61K38/193 , A61K38/196 , A61K41/00 , A61K41/0019 , A61M1/34 , A61M1/342 , A61M1/3441 , A61M1/3472 , A61M1/3482 , A61M1/3681 , A61M2202/0417 , A61M2205/50 , A61M2205/75 , A61N5/1028 , B01D15/00 , B01D29/50 , B01D37/00 , B01D61/02 , A61K2300/00
摘要： Apparatus for treating a patient, comprising a sterile device for removing soluble receptors for tumor necrosis factor-1 (TNF-1), tumor necrosis factor-2 (TNF-2), interleukin-1 (IL-1), interleukin-2 (IL-2), interleukin-6 (IL-6) or interferon-gamma (IFN-γ) from blood or plasma of a patient, and having inlet and outlet means for connection to a pump and tubing to circulate the blood or plasma through the device. Preferably the device comprises antibodies or antibody fragments that selectively bind to the soluble receptors, or cytokines selected from TNF-1, TNF-2, IL-1, IL-2, IL-6 and IFN-γ or epitopes thereof that selectively bind to the respective soluble receptors, immobilized on a column or a filter.
摘要翻译：用于治疗患者的装置，包括用于去除肿瘤坏死因子-1（TNF-1），肿瘤坏死因子-2（TNF-2），白细胞介素-1（IL-1），白细胞介素-2（IL-1） IL-2），白细胞介素-6（IL-6）或干扰素-γ（IFN-3），并且具有用于连接到泵和管道以将血液或血浆循环通过的入口和出口装置装置。优选地，该装置包含选择性结合可溶性受体或选自TNF-1，TNF-2，IL-1，IL-2，IL-6和IFN-3的细胞因子或选择性结合到其的表位的抗体或抗体片段各自的可溶性受体，固定在柱上或过滤器上。

9. 发明公开

EP1079875A2 METHOD AND COMPOSITIONS FOR TREATMENT OF CANCERS 有权
标题翻译：癌症治疗BY ultrapheresed拆除化合物120 000道尔顿
公开(公告)号：EP1079875A2
公开(公告)日：2001-03-07
申请号：EP99928331.0
申请日：1999-05-21
申请人： Lentz, M. Rigdon
发明人： Lentz, M. Rigdon
IPC分类号： A61M1/34 , A61K31/445 , A61K38/19 , A61K38/17
CPC分类号： A61K35/14 , A61K31/00 , A61K31/337 , A61K31/454 , A61K31/555 , A61K31/704 , A61K35/16 , A61K38/18 , A61K38/1816 , A61K38/193 , A61K38/196 , A61K41/00 , A61K41/0019 , A61M1/34 , A61M1/342 , A61M1/3441 , A61M1/3472 , A61M1/3482 , A61M1/3681 , A61M2202/0417 , A61M2205/50 , A61M2205/75 , A61N5/1028 , B01D15/00 , B01D29/50 , B01D37/00 , B01D61/02 , A61K2300/00
摘要： Apparatus for treating a patient, comprising a sterile device for removing soluble receptors for tumor necrosis factor-1 (TNF-1), tumor necrosis factor-2 (TNF-2), interleukin-1 (IL-1), interleukin-2 (IL-2), interleukin-6 (IL-6) or interferon-gamma (IFN-³) from blood or plasma of a patient, and having inlet and outlet means for connection to a pump and tubing to circulate the blood or plasma through the device. Preferably the device comprises antibodies or antibody fragments that selectively bind to the soluble receptors, or cytokines selected from TNF-1, TNF-2, IL-1, IL-2, IL-6 and IFN-³ or epitopes thereof that selectively bind to the respective soluble receptors, immobilized on a column or a filter.

10. 发明公开

EP3057621A4 POLYMERIC RADIATION-SOURCES 审中-公开
标题翻译： POLYMERE STRAHLUNGSQUELLEN
公开(公告)号：EP3057621A4
公开(公告)日：2017-06-21
申请号：EP14854116
申请日：2014-10-12
申请人： IP LIBERTY VISION CORP
发明人： FINGER PAUL T , WELLES TOBY , SIMON JAIME
IPC分类号： A61K51/02 , A61K51/12 , A61N5/10
CPC分类号： C08K5/42 , A61K51/065 , A61N5/1001 , A61N5/1017 , A61N5/1028 , A61N2005/1019 , A61N2005/1094 , C08F10/02 , C08G18/3206 , C08G18/7657 , C08G18/82 , C08G18/833 , C08G64/10 , C08G64/24 , C08F210/02 , C08F230/04

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