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1. 发明授权

EP2374488B1 An injection device with mode locking means 有权
标题翻译：具有模式锁定装置的注射装置
公开(公告)号：EP2374488B1
公开(公告)日：2018-03-21
申请号：EP11172344.1
申请日：2007-05-03
申请人： NOVO NORDISK A/S
发明人： Pedersen, Bennie, Peder, Smiszek , Kvolsberg, Bo , Møller, Claus, Schmidt
IPC分类号： A61M5/315
CPC分类号： A61M5/31553 , A61M5/20 , A61M5/24 , A61M5/31536 , A61M5/3155 , A61M5/31558 , A61M5/31566 , A61M5/31571 , A61M5/3158 , A61M5/31583 , A61M5/31585 , A61M2005/2407 , A61M2005/2411 , A61M2005/3125
摘要： An injection device comprising a housing, a dose setting member being operable to set a desired dose, a piston rod adapted to cooperate with a piston to cause a set dose to be expelled, and mode locking means. The mode locking means is adapted to be in a first extreme position and in a second extreme position. When the mode locking means is in the first extreme position the piston rod is prevented from cooperating with the piston, and when the mode locking means is in the second extreme position the dose setting member is prevented from being operated to set a dose. The mode locking means is adapted to be in the first extreme position during dose setting and the second extreme position during injection of a set dose. It is ensured that the liquid drug is not inadvertently expelled during dose setting and that blood or other body fluids is not sucked into the injection device during injection. Furthermore, inadvertent changing of the set dose during injection is prevented. The mechanism can readily be applied to injection devices which are not provided with a scale drum.

2. 发明授权

EP2352536B1 ELECTRONICALLY ASSISTED DRUG DELIVERY DEVICE 有权
标题翻译：电子辅助药物递送装置
公开(公告)号：EP2352536B1
公开(公告)日：2018-03-14
申请号：EP09752333.6
申请日：2009-11-05
申请人： Novo Nordisk A/S
发明人： JØRGENSEN, Bjarke, Dupont , PETERSEN, Jan, Lindhardt , LINNEBJERG, Steven , LUDVIGSEN, Henrik, Groth , HANSEN, Michael, Ejstrup , BEYERHOLM, Erik , ELAHI, Ramin, Nateghi , ROLSTED, Niels, Pryds , HOLME, Jens
IPC分类号： A61M5/24 , A61M5/31 , A61M5/315
CPC分类号： A61M5/31551 , A61M5/24 , A61M5/31535 , A61M5/31543 , A61M5/31558 , A61M5/3157 , A61M5/31575 , A61M5/3158 , A61M2005/2407 , A61M2005/2488 , A61M2005/3125 , A61M2005/3126 , A61M2005/3152 , A61M2205/3553 , A61M2205/3561 , A61M2205/3592 , A61M2205/50 , A61M2205/52 , A61M2205/8206 , G06F19/00
摘要： The present invention relates to electronically assisted drug delivery devices (100). The drug delivery device may include a Gray code type detector for sensing dosage data, wherein the detector comprises a code track consisting of a sequence of alternating markings and a plurality of detectors that are mutually spaced in a direction extending along the code track. The drug delivery device may also include a dosage selector (260) which is moved in a proximal direction upon dose setting and in a distal direction upon dose injection, where the dosage selector is latched in the end of dose position by a latching element, the latching element actuating an end of dose switch for signalling the end of dose state. The drug delivery device may also incorporate power-management arrangements which effectively minimizes power consumption for the incorporated electronic circuitry.

3. 发明公开

EP3288613A1 DRUG DELIVERY DEVICE WITH SPRING MECHANISM 有权
标题翻译：具有弹簧机构的药物递送装置
公开(公告)号：EP3288613A1
公开(公告)日：2018-03-07
申请号：EP16723677.7
申请日：2016-04-29
申请人： Novo Nordisk A/S
发明人： KIILERICH, Ebbe
IPC分类号： A61M5/20 , A61M5/315
CPC分类号： A61M5/31553 , A61M5/20 , A61M5/2033 , A61M5/31535 , A61M5/31536 , A61M5/3155 , A61M5/31558 , A61M5/31575 , A61M5/3158 , A61M5/31583 , A61M5/31593
摘要： A drug delivery device comprises an housing, an axially displaceable piston rod, a rotatable drive member, a spring housing, a torsion drive spring coupled to the spring housing respectively the drive member, dose setting means allowing a user to simultaneously set a dose amount to be expelled and strain the torsion drive spring correspondingly by rotation of the drive member, and a release member being axially moveable relative to the housing between a proximal initial position and an actuated distal release position. The spring housing is helically coupled to the housing such that the spring exerts a tangential force on the spring housing to thereby bias the spring housing in the proximal direction, whereby the spring housing thereby exerts a proximally directed biasing force on the release member. The spring housing can be moved helically in the distal direction when a distally directed force is exerted on the release member.

4. 发明公开

EP3102254A1 INJEKTIONSGERÄT 有权转让
标题翻译：注射装置
公开(公告)号：EP3102254A1
公开(公告)日：2016-12-14
申请号：EP15701676.7
申请日：2015-01-31
申请人： Haselmeier AG
发明人： KEITEL, Joachim
IPC分类号： A61M5/24 , A61M5/315
CPC分类号： A61M5/31551 , A61M5/24 , A61M5/31558 , A61M5/3156 , A61M5/3158 , A61M2005/2026 , A61M2205/581 , A61M2205/582
摘要： An injection device (1, 101, 201) has a housing (2, 102, 202), a dosing system (14, 114) for ejecting injection fluid out of a container (5, 105), a delivery part (18, 118), a slide (20, 120) and an adjustment part (22, 22', 122, 222). For adjustment of a quantity of injection fluid which is to be ejected out of the injection device (1, 101, 201), the adjustment part (22, 22', 122, 222) moves, in relation to the housing (2, 102, 202), in a first direction of rotation (45) about a longitudinal centre axis (10, 110, 210) of the injection device (1, 101, 201) and, on account of a third threaded connection (23, 123), in the distal direction. For ejecting the injection fluid, the adjustment part (22, 22', 122, 222) moves in a second direction of rotation (51), counter to the first direction of rotation (45), and moves in the proximal direction. The injection device (1, 101, 201) has a latching means (25, 125, 225), which defines at least one latching position of the adjustment part (22, 22', 122, 222) and which acts between the adjustment part (22, 22', 122, 222) and the housing (2, 102, 202). Each latching position of the latching means (25, 125, 225) is assigned a specific rotary position of the adjustment part (22, 22', 122, 222) in relation to the housing (2, 102, 202).

5. 发明公开

EP3071258A2 DRUG DELIVERY DEVICE WITH END OF DOSE FEEDBACK 审中-实审
标题翻译：具有剂量反馈终止的药物递送装置
公开(公告)号：EP3071258A2
公开(公告)日：2016-09-28
申请号：EP14799431.3
申请日：2014-11-17
申请人： Sanofi-Aventis Deutschland GmbH
发明人： BLANCKE, Stefan , TEUCHER, Axel , JUGL, Michael , SCHNEIDER, Christiane
IPC分类号： A61M5/24 , A61M5/28 , A61M5/315
CPC分类号： A61M5/31551 , A61M5/24 , A61M5/28 , A61M5/3146 , A61M5/31558 , A61M5/31561 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M2005/3104 , A61M2205/581 , A61M2205/582
摘要： A method and an assembly for providing a drug delivery device is presented. The assembly includes a housing and an end of dose feedback connection provides the user with an audible and/or tactile signal to indicate that the drug delivery is completed. A first section of the end of dose feedback connection is located on a distal portion of an inner sleeve and a second section of the end of dose feedback connection is located on the mid-body.
摘要翻译：一种用于提供药物输送装置（1）的方法和组件。该组件包括壳体（4）。剂量反馈连接的结束（81,82,83,85,86,87）为用户提供可听和/或可触知的信号以指示药物输送已完成。剂量反馈连接端的第一部分位于内套筒（29）的远端部分（84）上，并且剂量反馈连接端部的第二部分位于中间体（20）上。

6. 发明授权

EP2482875B1 DRIVE ASSEMBLY, PISTON ROD, DRUG DELIVERY DEVICE, AND USE OF A SPRING 有权
标题翻译：驱动装置，连杆药物输送设备和羽毛USE
公开(公告)号：EP2482875B1
公开(公告)日：2016-04-20
申请号：EP10757781.9
申请日：2010-09-29
申请人： Sanofi-Aventis Deutschland GmbH
发明人： VEASEY, Robert , BILTON, Simon, Lewis , JONES, Christopher , KOUYOUMJIAN, Garen , MACDONALD, Catherine, Anne
IPC分类号： A61M5/24 , A61M5/315
CPC分类号： A61M5/24 , A61M5/31541 , A61M5/31543 , A61M5/31555 , A61M5/31556 , A61M5/31558 , A61M5/3156 , A61M5/3158 , A61M5/31585 , A61M5/31593 , A61M2005/2407 , A61M2005/2488 , A61M2005/31508 , A61M2205/581 , A61M2205/582

7. 发明公开

EP2983742A1 HAND-HELD DRUG INJECTION DEVICE AND DOSE SETTING LIMITER MECHANISM THEREFOR 审中-公开
标题翻译：手持式药物注入器具剂量设定控制机制THEREFOR
公开(公告)号：EP2983742A1
公开(公告)日：2016-02-17
申请号：EP14717719.0
申请日：2014-04-08
申请人： SANOFI
发明人： BAYER, Stefan , BERNING, Daniel , BLANK, Philippe , WILDEN, Björn , PELZER, Wolfgang
IPC分类号： A61M5/20 , A61M5/315 , A61M5/31
CPC分类号： A61M5/31553 , A61M5/2033 , A61M5/31541 , A61M5/31558 , A61M5/31563 , A61M5/3157 , A61M5/31575 , A61M5/31583 , A61M5/31585 , A61M5/31593 , A61M2005/202 , A61M2005/2086 , A61M2005/3126 , A61M2005/314 , A61M2005/3143 , A61M2005/31508 , A61M2005/3152 , A61M2005/3154 , A61M2205/581
摘要： The present invention relates to a drive mechanism of a drug delivery device for dispensing of a dose of a medicament, the mechanism comprising: —a housing (20), —a piston rod (120) extending in an axial direction (1, 2) to operably engage with a piston (14) of a cartridge (12), —a drive sleeve (90) rotatably supported in the housing (20), at least partially enclosing the piston rod (120), the drive sleeve (90) is operably releasable from the piston rod (120) for setting of a dose and the drive sleeve (90) is operably engageable with the piston rod (120) for dispensing of the dose, —a dose limiting member (130) threadedly engaged with the drive sleeve (90), rotatably locked to the housing (20) and being displaceable in axial direction (1, 2) in response to a rotation of the drive sleeve (90) relative to the piston rod (120), —at least one stop member (124) provided on the piston rod (120) to engage with the dose limiting member (130) for impeding a further displacement of the drive sleeve (90) relative to the piston rod (120), when a maximum dose configuration has been reached.

8. 发明授权

EP1827538B2 INJECTION DEVICE 有权
公开(公告)号：EP1827538B2
公开(公告)日：2015-07-01
申请号：EP05815508.6
申请日：2005-11-29
申请人： NOVO NORDISK A/S
发明人： RADMER, Bo , MØLLER, Claus, Schmidt , GROTH, Lars, Mørch , THØGERSEN, Klaus
IPC分类号： A61M5/315 , A61M5/24
CPC分类号： A61M5/31545 , A61M5/24 , A61M5/31528 , A61M5/31535 , A61M5/31541 , A61M5/31548 , A61M5/3155 , A61M5/31551 , A61M5/31558 , A61M5/31585 , A61M2005/2407 , A61M2005/3125 , A61M2005/3126
摘要： The application concerns an injection device for apportioning set doses of a drug from a reservoir (40) to a subject. The injection device comprises a housing having an interior thread (101,112) formed as an outwardly pointing thread (101,112) carried on an upstanding tower centrally located in the pen shaped device. This outwardly pointing thread (101,112) forms a first thread connection with the interior thread of the rotatable scale drum (90). The injection device further comprises a driver (70) for moving the piston rod (120) forward when moved axially. The driver (70) operates the piston rod (120) through a second thread connection having a pitch different than the first thread connection.

9. 发明公开

EP2790753A1 INJECTION PEN WITH MECHANICAL DOSE DISPLAY COMPRISING LARGE CIPHERS 审中-公开
标题翻译：有大量注射笔，机械特性量指示剂
公开(公告)号：EP2790753A1
公开(公告)日：2014-10-22
申请号：EP12806002.7
申请日：2012-12-10
申请人： Novo Nordisk A/S
发明人： RØRVIG, Simon
IPC分类号： A61M5/24 , A61M5/31 , A61M5/315
CPC分类号： A61M5/31573 , A61M5/24 , A61M5/31528 , A61M5/31551 , A61M5/31553 , A61M5/31558 , A61M5/3156 , A61M5/31593 , A61M2005/3126
摘要： The present invention relates to an injection device (1) having a mechanical dose size dis- play wherein a first scale drum (10) carrying a series of first ciphers (11) and a second scale drum (20) carrying a series of second ciphers (21) are both rotatable and axially moveable relatively to a housing (2) of the injection device in such a way that one of the first ciphers (11) and one of the a second ciphers (21) appears simultaneously in a window provided in the housing (2) thereby informing the user of the set dose. Bothe the first scale drum (10) and the second drum (20) preferable carries five ciphers (11, 21) around one full circumferential perimeter. The ciphers (11, 21) are provided in different circumferential circles and/or helically provided.

10. 发明公开

EP2586477A2 Injector apparatus having stored energy 审中-公开
标题翻译： Injektor mit gespeicherter Energie
公开(公告)号：EP2586477A2
公开(公告)日：2013-05-01
申请号：EP13152462.1
申请日：2010-10-15
申请人： Owen Mumford Limited
发明人： Cowe, Toby
IPC分类号： A61M5/20 , A61M5/315 , A61M5/24 , A61M5/00
CPC分类号： A61M5/31553 , A61M5/20 , A61M5/2033 , A61M5/24 , A61M5/3129 , A61M5/315 , A61M5/31536 , A61M5/31548 , A61M5/31551 , A61M5/31556 , A61M5/31558 , A61M5/31561 , A61M5/31575 , A61M5/31583 , A61M2005/2407 , A61M2005/2492 , A61M2005/3103 , A61M2205/581 , A61M2205/583
摘要： An injector apparatus comprises a housing (10 1 , 10 2 ) for a cartridge or syringe, a plunger (40) for cooperating in use with the cartridge or syringe to express successive doses, a dose setting arrangement (16, 20) to select a dose volume, and a drive mechanism (22, 24) releasable to advance said plunger in respective predetermined increments of magnitude to express said successive doses. The drive mechanism includes a drive spring (22) for imparting movement directly or indirectly to said plunger (40), and said dose setting arrangement comprises a dose setting element (16) moveable in a dose setting routine to define a magnitude of an increment of movement of said plunger for a given dose. The drive mechanism further includes a clutch arrangement (56) operable during said dose setting routine to inhibit forward movement of the plunger and/or to isolate said dose setting element from the force of said drive spring.
摘要翻译：注射器装置包括用于药筒或注射器的壳体（10 1，10 2），用于与药筒或注射器配合使用以表示连续剂量的柱塞（40），剂量设定装置（16,20）剂量体积和驱动机构（22,24），其可释放以使所述活塞以相应的预定增量递增以表示所述连续剂量。驱动机构包括用于直接或间接地向所述柱塞（40）运动的驱动弹簧（22），并且所述剂量设定装置包括可在剂量设定程序中移动的剂量设定元件（16），以定义增量的幅度所述柱塞在给定剂量下的运动。驱动机构还包括离合器装置（56），其可在所述剂量设定程序期间操作以阻止柱塞的向前运动和/或使所述剂量设定元件与所述驱动弹簧的力隔离。

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