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    • 5. 发明公开
    • MINERAL TRIOXIDE AGGREGATE (MTA) COMPOSITION AND USE
    • 美国海军陆战队(MTA)-ZUSAMMENSETZUNG UND IHRE VERWENDUNG
    • EP2470154A4
    • 2016-06-01
    • EP10811306
    • 2010-08-27
    • DENTOSOLVE APS
    • LØVSCHALL HENRIKKJAERGAARD PIASKOVHUS THOMSEN JESPER
    • A61K6/06
    • A61K6/0835A61K6/0038A61K6/0041A61K6/0073A61K6/0606A61K6/0612A61K6/0631A61K6/0668A61K6/0675
    • The present application discloses a fast-setting mineral trioxide aggregate (MTA) with fluoride release for practical treatment of diseases in teeth and bone, e.g. for caries treatment and/or prevention. The cariostatic MTA contain calcia-silica-alumina cement with moderately increased tricalcium aluminate content allowing high calcium hydroxide release. The MTA composition support remineralization and biomineralization, and it is suitable for stimulation of hard tissue regeneration. MTA embodiments contain superplasticizer and nanosilicate for improved mechanical properties. The MTA compositions include optional radiocontrast and nano-enriched leachable fluorine, nitrate, strontium, and phosphate. The fast-setting MTA paste exhibits flow-to-clay-like consistency, which allows new practical applications including cavity lining, temporary restoration, bonding, and cementations in one MTA embodiment. The high calcium hydroxide and high fluoride release are suitable for caries prevention and treatment, and per se inhibition of dental symptoms.
    • 本申请公开了一种具有氟化物释放的快速凝固的三氧化二砷骨架(MTA),用于实际治疗牙齿和骨骼中的疾病,例如, 用于龋齿治疗和/或预防。 耐腐蚀MTA含有钙铝硅酸盐水泥,具有适度增加的铝酸钙含量,允许高氢氧化钙释放。 MTA组合物支持再矿化和生物矿化,适用于刺激硬组织再生。 MTA实施方案包含用于改善机械性能的超增塑剂和纳米硅酸盐。 MTA组合物包括可选的放射性对比和纳米富集的可浸出氟,硝酸盐,锶和磷酸盐。 快速凝固的MTA糊状物显示出流到粘土的稠度,其允许在一个MTA实施方案中的新的实际应用,包括腔衬,临时恢复,粘合和胶结。 高氢氧化钙和高氟化物释放适用于龋齿预防和治疗,并且本身抑制牙科症状。
    • 7. 发明公开
    • ONE-PACK DENTAL ADHESIVE
    • 单件牙齿责任
    • EP2835128A4
    • 2015-11-11
    • EP13769369
    • 2013-03-15
    • KURARAY NORITAKE DENTAL INC
    • TAKEI MITSURUNOJIRI YAMATO
    • A61K6/00A61K6/083
    • A61K6/0835A61K6/0023A61K6/0047A61K6/005A61K6/0073A61K6/0085A61K6/0091A61K6/0094A61K6/024A61K6/025C08L33/10C08L77/00C08L27/06C08L25/06C08L33/26C08L43/02
    • The present invention provides a one-part dental adhesive that exhibits excellent adhesive properties to both enamel and dentin and that has high storage stability and ambient-light stability. The present invention is a one-part dental adhesive including 1 to 30 weight% of a phosphoric acid group-containing monofunctional (meth)acrylate compound (a), 10 to 50 weight% of a water-soluble polymerizable monomer (b), 5 to 50 weight% of a hydrophobic crosslinkable (meth)acrylate compound (c), water (d), and a polymerization initiator (e). The water-soluble polymerizable monomer (b) includes a combination of a monofunctional (meth)acrylamide compound (b-1) having a particular structure and a water-soluble crosslinkable (meth)acrylic monomer (b-2). The weight ratio between the monofunctional (meth)acrylamide compound (b-1) and the water-soluble crosslinkable (meth)acrylic monomer (b-2) is 10 : 1 to 1 : 5.
    • 本发明提供了一种对牙釉质和牙本质具有优异的粘合性能并且具有高储存稳定性和环境光稳定性的一部分牙科粘合剂。 本发明是含有1〜30重量%的含磷酸基单官能(甲基)丙烯酸酯化合物(a),10〜50重量%的水溶性聚合性单体(b),5 至50重量%的疏水性交联性(甲基)丙烯酸酯化合物(c),水(d)和聚合引发剂(e)。 水溶性聚合性单体(b)包含具有特定结构的单官能(甲基)丙烯酰胺化合物(b-1​​)和水溶性交联性(甲基)丙烯酸系单体(b-2)的组合。 单官能(甲基)丙烯酰胺化合物(b-1​​)与水溶性交联性(甲基)丙烯酸系单体(b-2)的重量比为10:1〜1:5。