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1. 发明公开

EP3320944A1 MULTI-ELECTRODE CATHETER FOR PREVENTING PHYSIOLOGICAL FLUID FLOW RESTRICTION 审中-实审转让
标题翻译：用于防止生理流体流动限制的多电极导管
公开(公告)号：EP3320944A1
公开(公告)日：2018-05-16
申请号：EP17200645.4
申请日：2017-11-08
申请人： Biosense Webster (Israel) Ltd.
发明人： RUBINSTEIN, Vladimir , AUERBACH, Shmuel , ULTCHIN, Yigal , BAR-TAL, Meir , HOLANDER, Ludwig Eliezer
IPC分类号： A61M25/10 , A61B18/14 , A61B5/042 , A61B5/06
CPC分类号： A61B18/1492 , A61B5/0084 , A61B5/027 , A61B5/0422 , A61B5/062 , A61B5/4848 , A61B5/6853 , A61B5/6857 , A61B5/6858 , A61B5/6869 , A61B5/6885 , A61M25/007 , A61M25/1002 , A61M25/1011 , A61M25/10188 , A61M2025/0166 , A61M2025/1013
摘要： A medical apparatus, used to acquire electrical activity of patient anatomy, is provided which includes an elongated body and a tip portion coupled to the elongated body. The tip portion includes one or more inflatable sections. Each inflatable section has a plurality of electrodes disposed on one of: (i) an outer surface of the one or more inflatable sections; and (ii) an inner surface and the outer surface of the one or more inflatable sections. The one or more inflatable sections, when inflated, cause a portion of the plurality of electrodes to contact a surface of an organ and provide a pathway for physiological fluid to flow through the tip portion. In one embodiment, the tip portion is a tulip balloon tip portion. In another embodiment, the tip portion is an inflatable tip portion having one or more concentrically wound inflatable sections.
摘要翻译：提供了用于获取患者解剖结构的电活动的医疗设备，其包括细长主体和联接到细长主体的尖端部分。尖端部分包括一个或多个可充气部分。每个可膨胀部分具有设置在以下之一上的多个电极：（i）所述一个或多个可膨胀部分的外表面; 和（ii）一个或多个可膨胀部分的内表面和外表面。所述一个或多个可膨胀部分在充气时导致所述多个电极的一部分接触器官的表面并为生理流体流过所述末端部分提供通路。在一个实施例中，尖端部分是郁金香球囊尖端部分。在另一个实施例中，尖端部分是具有一个或多个同心缠绕的可膨胀部分的可充气尖端部分。

2. 发明公开

EP3182887A1 METHODS, DEVICES AND SYSTEMS FOR SENSING, MEASURING AND/OR CHARACTERIZING VESSEL AND/OR LESION COMPLIANCE AND/OR ELASTANCE CHANGES DURING VASCULAR PROCEDURES 审中-公开
标题翻译：测量和/或表征血管和/或病变顺应性和/或血管手术过程中的变化的方法，装置和系统
公开(公告)号：EP3182887A1
公开(公告)日：2017-06-28
申请号：EP15833050.6
申请日：2015-08-21
申请人： Cardiovascular Systems, Inc.
发明人： KOHLER, Robert E. , HIGGINS, Joseph P.
IPC分类号： A61B5/02 , A61B5/027
CPC分类号： A61B5/02007 , A61B5/02158 , A61B5/026 , A61B5/027 , A61B5/4836 , A61B5/6851 , A61B5/6852 , A61B5/7246 , A61B5/742 , A61B5/7475 , A61B2560/0238 , A61B2560/0475 , A61B2562/0247
摘要： The present system is directed in various embodiments to methods, devices and systems for sensing, measuring and evaluating compliance and/or elastance in a bodily conduit. In other embodiments, the methods, devices and systems sense, measure, determine, display and/or interpret compliance and/or elastance in a bodily conduit and/or a lesion within the bodily conduit using fractional flow reserve and/or flow velocity measurements as well as resistance to flow calculations in certain embodiments. In all embodiments, the sensing, measuring, determining, displaying and/or interpreting may occur before, during and/or after a procedure performed within the bodily conduit. An exemplary conduit comprises a blood vessel and an exemplary procedure comprises a vascular procedure such as atherectomy, angioplasty, stent placement and/or biovascular scaffolding.
摘要翻译：本系统在各种实施例中涉及用于感测，测量和评估身体导管中的顺应性和/或弹性的方法，装置和系统。在其他实施例中，方法，装置和系统使用分流预留和/或流速测量来感测，测量，确定，显示和/或解释身体管道内的身体管道和/或病变中的顺应性和/或弹性以及在某些实施例中对流动计算的阻力。在所有实施例中，感测，测量，确定，显示和/或解释可以发生在体内导管内执行的过程之前，期间和/或之后。示例性导管包括血管，并且示例性程序包括血管手术，例如粥样斑块切除术，血管成形术，支架放置和/或生物血管支架。

3. 发明公开

EP3133987A1 INTRAVASCULAR DEVICES, SYSTEMS, AND METHODS HAVING SEPARATE SECTIONS WITH ENGAGED CORE COMPONENTS 有权转让
标题翻译：血管内的设备，系统和与啮合核心组件独立的部分方法
公开(公告)号：EP3133987A1
公开(公告)日：2017-03-01
申请号：EP15783695.8
申请日：2015-04-20
申请人： Koninklijke Philips N.V.
发明人： BURKETT, David H. , HENDERSON, Eric , SPAARGAREN, Kevin
IPC分类号： A61B5/027 , A61B5/02 , A61B5/00
CPC分类号： A61B5/6851 , A61B5/0215 , A61B5/027 , A61B2562/12 , A61B2562/227
摘要： Intravascular devices, systems, and methods are disclosed. In some instances, the intravascular device is a guide wire that includes separate sections with engaged core components. For example, a sensing guide wire can include a proximal portion having a proximal core member and at least one proximal electrical conductor and a distal portion coupled to the proximal portion, the distal portion having a distal core member, a sensing element, and at least one distal electrical conductor coupled to the sensing element, wherein engagement structures of the proximal and distal core members are engaged and wherein the at least one distal electrical conductor is coupled to the at least one proximal electrical conductor such that the at least one proximal electrical conductor is in electrical communication with the sensing element. Methods of making, manufacturing, and/or assembling such intravascular devices and associated systems are also provided.
摘要翻译：血管内设备，系统和方法游离缺失盘。在某些情况下，血管内装置是导丝确实包括与接合核心组件分离的部分。对于实施例，感测导线可包括具有近端芯构件和至少一个近侧电导体和耦合到所述近侧部分的远侧部分的近侧部分，其具有前端侧芯材，感测元件，并且至少所述远端部分耦合到所述感测元件，worin近端和远端芯构件的接合结构一个远端电导体接合和worin的至少一个远端的电导体被耦合到所述至少一个近端电导体已审查做的至少一个近端电导体与所述感测元件电连通。因此，提供制造，制造和/或组装寻求血管内装置和相关联的系统的方法。

5. 发明公开

EP3099226A1 LUMINAL IMPEDANCE DEVICE WITH INTEGRATED CIRCUIT MODULES 有权
标题翻译： LUMINALE IMPEDANZVORRICHTUNG MIT INTEGRIERTEN SCHALTUNGSMODULEN
公开(公告)号：EP3099226A1
公开(公告)日：2016-12-07
申请号：EP15743045.5
申请日：2015-01-30
申请人： 3DT Holdings, LLC
发明人： KASSAB, Ghassan, S. , MINAR, Chris , SOYKAN, Orhan , COMBS, William
IPC分类号： A61B5/053 , A61M25/10 , A61M25/00
CPC分类号： A61B5/0538 , A61B5/0022 , A61B5/01 , A61B5/0205 , A61B5/02055 , A61B5/0215 , A61B5/026 , A61B5/027 , A61B5/036 , A61B5/1076 , A61B5/4509 , A61B5/6851 , A61B5/6852 , A61B5/6853 , A61B5/7225 , A61B2560/0214 , A61B2560/0406 , A61B2560/0462 , A61B2560/0468 , A61B2562/02 , A61B2562/0247 , A61B2562/0271 , A61B2562/046 , A61B2562/06 , A61B2562/166 , A61B2562/222
摘要： Impedance devices with integrated circuit modules and method of using the same to obtain luminal organ information. In one embodiment, a device comprises an elongated body for at least partial insertion into a mammalian luminal organ and having a first conductor extending therethrough, a proximal electrical unit connected to the elongated body to deliver power along the first conductor, and a sensor substrate located at or near a distal end of the elongated body and comprising a circuit module operable and/or configured to direct the sizing portion to obtain sizing data and the pressure sensor to obtain pressure data, and facilitate transmission of the sizing data and/or the pressure data to the proximal electrical unit.
摘要翻译：具有集成电路模块的阻抗器件及其使用方法获得腔内器官信息。在一个实施例中，装置包括用于至少部分插入哺乳动物腔内器官并具有延伸穿过其中的第一导体的细长主体，连接到细长主体以沿着第一导体输送功率的近端电单元，以及位于在细长体的远端处或附近，并且包括可操作和/或构造成引导施胶部分以获得施胶数据和压力传感器以获得压力数据的电路模块，并且便于传送尺寸数据和/或压力数据到近端电气单元。

6. 发明公开

EP2814382A1 METHOD AND SYSTEM FOR DETECTING CARDIAC TAMPONADE IN A PATIENT 有权转让
标题翻译：系统ZE ERKENNUNG EINER HERZTAMPONADE BEI EINEM PATITENTEN
公开(公告)号：EP2814382A1
公开(公告)日：2014-12-24
申请号：EP13710595.3
申请日：2013-02-12
申请人： Ottevanger, Egbert Jan Constant , Rienks, Rienk , Muijs van de Moer, Wouter Matthijs
发明人： OTTEVANGER, Egbert Jan Constant , MUIJS VAN DE MOER, Wouter Matthijs
IPC分类号： A61B5/0215 , A61B5/029 , A61B5/03 , A61B5/053 , A61B8/06
CPC分类号： A61B5/7275 , A61B5/0004 , A61B5/02028 , A61B5/0205 , A61B5/0215 , A61B5/02158 , A61B5/027 , A61B5/029 , A61B5/03 , A61B5/053 , A61B5/0538 , A61B5/686 , A61B5/6869 , A61B5/7246 , A61B8/065 , A61B8/12
摘要： System for indicating a possibility a cardiac tamponade occurring in a patient, comprising: —a right atrium pressure sensor, configured for measuring a right atrium pressure in a right atrium of the patient; —an intra pericardial pressure sensor, configured for measuring an intra pericardial pressure in a portion of an intra-pericardial space of the patient; —a processing device that is operatively connected to the pressure sensors, is provided with a predetermined statistical distribution of pressure versus tamponade probabilities, and is configured for: —determining a trans-mural pressure difference between the right atrium pressure and the intra pericardial pressure; —comparing the trans-mural pressure difference with the statistical distribution, and —indicating the possibility of cardiac tamponade occurrence, based on the trans-mural pressure difference comparison.
摘要翻译：用于指示患者发生心脏填塞的可能性的系统，包括： - 右心房压力传感器，被配置为测量患者右心房中的右心房压力; - 心包内压力传感器，构造成用于测量患者的心包内空间的一部分内的心包内压力; - 操作性地连接到所述压力传感器的处理装置被提供有压力对压缩概率的预定统计分布，并且被配置为： - 确定右心房压力和心包内压力之间的跨壁压差; 通过统计分布比较跨壁压差，并根据跨壁压差比较，说明心包填塞发生的可能性。

7. 发明授权

EP2185062B1 KATHETERSYSTEM MIT OPTISCHER SONDE UND VERFAHREN ZUR APPLIKATION EINER OPTISCHEN SONDE IN EIN KATHETERSYSTEM 有权
标题翻译：与用于光学探针的导管系统中应用光学传感器和方法导管系统
公开(公告)号：EP2185062B1
公开(公告)日：2014-03-19
申请号：EP08785090.5
申请日：2008-07-25
申请人： UP-MED GmbH
发明人： PFEIFFER, Ulrich , MOULAS, Daniel , KNOLL, Reinhold
IPC分类号： A61B5/145 , A61B5/027 , A61B5/1459 , A61B5/00 , A61M25/00 , A61M25/01
CPC分类号： A61M25/00 , A61B5/027 , A61B5/14542 , A61B5/1459 , A61B5/412 , A61M25/0021 , A61M25/0125 , A61M2025/0008 , A61M2025/0079

8. 发明公开

EP1933701A2 METHOD AND DEVICE FOR DETERMINING FLOW IN A BLOOD VESSEL 有权
标题翻译：方法和设备确定流在血管
公开(公告)号：EP1933701A2
公开(公告)日：2008-06-25
申请号：EP06783918.3
申请日：2006-09-12
申请人： Martil Instruments B.V.
发明人： POP, Gheorghe, Aurel, Marie
IPC分类号： A61B5/027 , A61B5/053
CPC分类号： A61B5/027 , A61B5/0295 , A61B5/0535
摘要： The invention relates to a method and device for determining the flow in a blood vessel, comprising of determining the relation between the shear rate and the impedance of flowing blood, measuring the impedance in the blood in a cross-section of the blood vessel, determining the shear rate from this relation and the measured impedance, determining the size of the cross-section of the blood vessel, selecting a theoretical relative flow distribution over the blood vessel cross-section, determining the average flow speed on the basis of the average shear rate and the relative flow distribution, and determining the flow volume from the determined average flow speed and the cross-section.

9. 发明公开

EP1434519A2 EINRICHTUNG ZUM EINFÜHREN IN KÖRPERHOHLORGANE 审中-公开
标题翻译：设备引入车身空腔脏器
公开(公告)号：EP1434519A2
公开(公告)日：2004-07-07
申请号：EP02782853.2
申请日：2002-10-08
申请人： Schregel, Werner, Prof. Dr. Med.
发明人： Schregel, Werner, Prof. Dr. Med.
IPC分类号： A61B5/00 , A61B5/0215 , A61B5/028 , A61B8/06
CPC分类号： A61B5/0084 , A61B5/0215 , A61B5/027 , A61B5/028 , A61B5/1459
摘要： The invention relates to a device for introducing into hollow organs of the body, in particular into blood vessels. Said device consists of a substantially longitudinal instrument comprising a measuring device that is located in a closed channel in the vicinity of the device end that is introduced into the hollow organ of the body, in particular the blood vessel. The aim of the invention is to improve a device known per se and to widen its range of application. To achieve this, the device is provided with a measuring device that is suitable for measuring the composition and/or the characteristics of the blood, and/or a measuring device that is suitable for measuring the temperature of the blood flowing in the blood vessel and/or values that can be determined by temperature measurements, in particular the flow rate, and/or a measuring device for measuring haemodynamic parameters of the blood and/or values that can be determined by pressure measurements.

10. 发明公开

EP1223859A2 METHOD AND APPARATUS TO MEASURE BLOOD FLOW BY AN INTRODUCED VOLUME CHANGE 有权
标题翻译：设备技术确定流通过分散体积变化
公开(公告)号：EP1223859A2
公开(公告)日：2002-07-24
申请号：EP00986829.0
申请日：2000-10-19
申请人： TRANSONIC SYSTEMS, INC.
发明人： KRIVITSKI, Nikolai, M. , DROST, Cornelius, J.
IPC分类号： A61B5/0275 , G01F1/704
CPC分类号： A61B5/027 , A61B5/0215 , A61B5/0255 , A61B5/026 , A61B5/0275 , A61B5/6852 , A61M25/00 , G01F1/34 , G01F1/66 , G01F1/704 , G01F1/708 , G01F25/0007
摘要： A method and apparatus for determining an initial flow rate in a conduit is disclosed. A known change is made to the flow to be measured, resulting changes (or values corresponding to these changes), or relative changes in the flow to be measured are monitored and the initial flow in the conduit is calculated from the value of the known change and monitored changes. Devices to practice the method include catheters having one or two sensors and one or two sites for introducing the volume change.

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