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    • 4. 发明公开
    • Food and beverages for treating abdominal discomfort
    • Lebensmittel oderGetränkzur Behandlung von abdominalen Schmerzen
    • EP2463375A2
    • 2012-06-13
    • EP12001429.5
    • 2004-09-30
    • Meiji Co., Ltd.
    • Furuichi, KeisukeYoda, Nobuo
    • C12P7/42A61K31/192A61P19/08A23L1/30A23C9/152
    • A23L2/52A23C9/12A23C9/1203A23C9/1209A23C9/20A23L33/10A23V2002/00A61K31/192C12P7/42A23V2200/32
    • Food and beverages for improving abdominal discomfort, comprising a composition comprising 1,4-dihydroxy-2-naphthoic acid obtained by
      (i) a process for producing 1,4-dihydroxy-2-naphtoic acid comprising initiating the culture of 1,4-dihydroxy-2-naphthoic acid producing bacteria belonging to propionic acid bacteria under anaerobic conditions and culturing the bacteria under aeration into the medium when the concentration of a carbon source in the medium is 3.5% by mass or less, or
      (ii) a process for producing 1,4-dihydroxy-2-naphtoic acid, comprising culturing 1,4-dihydroxy-2-naphthoic acid producing bacteria belonging to propionic acid bacteria under anaerobic conditions, adding a carbon source to the obtained culture and preserving the culture at 3 to 20 °C under weak alkaline conditions, or
      (iii) a process for producing 1,4-dihydroxy-2-naphtoic acid, comprising initiating the culture of 1, 4-dihydroxy-2-naphthoic acid producing bacteria belonging to propionic acid bacteria under anaerobic conditions, culturing the bacteria under aeration into a medium when the concentration of a carbon source in the medium is 3.5% by mass or less, adding the carbon source to the obtained culture and preserving the culture at 3 to 20 °C under weak alkaline conditions, as an active ingredient.
    • 包含通过(i)1,4-二羟基-2-萘甲酸的制造方法得到的包含1,4-二羟基-2-萘甲酸的组合物的食品和饮料,其包括引发1,4-二羟基-2-萘甲酸的培养, 或二氧基-2-萘甲酸生产菌,在厌氧条件下属于丙酸菌,并且当培养基中碳源的浓度为3.5质量%以下时,通气培养细菌培养至培养基中,或(ii) 制备1,4-二羟基-2-萘甲酸,包括在厌氧条件下培养属于丙酸细菌的1,4-二羟基-2-萘酸生产菌,向获得的培养物中加入碳源,并在3℃保存培养物 在弱碱性条件下为20℃,或(iii)生产1,4-二羟基-2-萘酸的方法,包括引发属于丙酸菌的1,4-二羟基-2-萘酸生产细菌的培养物 全日空 有氧条件下,培养基中的碳源浓度为3.5质量%以下时,通入培养细菌至培养基中,向得到的培养物中加入碳源,在弱碱性条件下在3〜20℃保存培养基 条件,作为活性成分。