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1. 发明授权

EP2632371B1 COMPATIBLE CRYOGENIC COOLING SYSTEM 有权
公开(公告)号：EP2632371B1
公开(公告)日：2023-02-01
申请号：EP11835372.1
申请日：2011-09-15
发明人： LALONDE, Jean-Pierre
IPC分类号： A61B18/02 , F25B25/02 , F25B40/02

2. 发明授权

EP2771055B1 SYSTEMS FOR VARIABLE INJECTION FLOW 有权
公开(公告)号：EP2771055B1
公开(公告)日：2021-02-17
申请号：EP12788671.1
申请日：2012-10-18
发明人： LALONDE, Jean-Pierre , LASKE, Timothy G. , LUECKGE, Claudia , WITTENBERGER, Dan , SABBAGHE-KERMANI, Ramin , SERAJ, Mahmoud Kabir , GROVES, Regina E.
IPC分类号： A61M25/00 , A61B18/02 , A61M39/28

3. 发明授权

EP2081511B1 APPARATUS FOR INFLATING AND DEFLATING BALLOON CATHETERS 有权转让
公开(公告)号：EP2081511B1
公开(公告)日：2021-01-13
申请号：EP07815848.2
申请日：2007-09-20
发明人： ABBOUD, Marwan , MAHROUCHE, Rachid , HARMOUCHE, Chadi , MIHALIK, Teresa , DESROCHERS, Gilles
IPC分类号： A61B18/02 , A61F7/00 , A61M25/10

4. 发明授权

EP2528527B1 PARTIALLY COMPLIANT BALLOON DEVICE 有权
公开(公告)号：EP2528527B1
公开(公告)日：2020-01-01
申请号：EP11736556.9
申请日：2011-01-21
申请人： Medtronic Cryocath LP
发明人： WITTENBERGER, Dan
IPC分类号： A61B18/02 , A61M25/10

5. 发明授权

EP2470260B1 METHOD AND SYSTEM FOR PREVENTING NERVE INJURY DURING A MEDICAL PROCEDURE 有权
公开(公告)号：EP2470260B1
公开(公告)日：2019-03-13
申请号：EP10749585.5
申请日：2010-08-31
申请人： Medtronic Cryocath LP
发明人： COULOMBE, Nicolas , WITTENBERGER, Dan
IPC分类号： A61N1/08 , A61N1/36 , A61B5/0488 , A61B18/02 , A61B18/14 , G06F19/00 , A61B5/00 , A61B17/32 , A61B18/20 , A61B5/0492 , A61B5/053 , A61B5/08 , A61B17/22 , A61N1/37 , A61B18/00 , A61B5/04

6. 发明授权

EP2598064B1 DUAL INJECTION TUBE CRYOCATHETER 有权
公开(公告)号：EP2598064B1
公开(公告)日：2018-10-17
申请号：EP11738907.2
申请日：2011-07-20
申请人： Medtronic Cryocath LP
发明人： WITTENBERGER, Dan , LUECKGE, Claudia , LANE, Miriam
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/00166 , A61B2018/0022 , A61B2018/00642 , A61B2018/0212 , A61B2090/064
摘要： A medical device includes a catheter body having a first injection lumen, a second injection lumen, and an exhaust lumen, where the first injection lumen provides a fluid flow rate greater than a fluid flow rate provided by the second injection lumen; an expandable element coupled to the catheter body in fluid communication with the first and second injection lumens; a cryogenic fluid source in fluid communication with the first and second injection lumens; a valve in fluid communication with the first and second injection lumens to selectively allow fluid flow to at least one of the first and second injection lumens; a pressure sensor in fluid communication with an interior defined by the expandable element; and a controller in communication with the pressure sensor programmed to regulate fluid flow through the first injection lumen based at least in part on a signal from the pressure sensor.

7. 发明公开

EP3317593A1 N2O LIQUEFACTION SYSTEM WITH SUBCOOLING HEAT EXCHANGER FOR MEDICAL DEVICE 有权
标题翻译：带过冷热交换器的医疗器械N2O液化系统
公开(公告)号：EP3317593A1
公开(公告)日：2018-05-09
申请号：EP16816882.1
申请日：2016-06-10
申请人： Medtronic Cryocath LP
发明人： MAHROUCHE, Rachid , MONGER, Eric , TZONEV, Vladimir
IPC分类号： F25B40/02 , A61B18/02 , F25J1/02
摘要： A system and kit for using a source of low-pressure refrigerant for a cryotherapy procedure and for subcooling a cryotherapy refrigerant. The system may generally include a fluid reservoir and a fluid flow path in thermal exchange with the fluid reservoir, the fluid flow path including a first thermal exchange device in thermal exchange with the fluid reservoir, a compressor in fluid communication with the first thermal exchange device, a condenser, a reversing valve located between the compressor and the condenser, a second thermal exchange device located between the reversing valve and the compressor, and an expansion valve located between the condenser and the thermal exchange device. The third thermal exchange device may be configured to be in fluid communication with the cryotherapy console and configured to place a secondary refrigerant within the first fluid flow path in thermal communication with a secondary refrigerant of the cryotherapy system.

8. 发明公开

EP3169259A4 CARDIAC CRYOLIPOLYSIS FOR THE TREATMENT OF CARDIAC ARRHYTHMIA 无效
公开(公告)号：EP3169259A4
公开(公告)日：2018-03-21
申请号：EP15821981
申请日：2015-06-15
申请人： MEDTRONIC CRYOCATH LP
发明人： WITTENBERGER DAN
IPC分类号： A61B18/02 , A61B18/00
CPC分类号： A61B18/02 , A61B2018/00023 , A61B2018/0025 , A61B2018/00351 , A61B2018/00375 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： A system, device, and method for the treatment of cardiac arrhythmia by, specifically, cryolipolysis of non-myocardial tissue and cryoablation of myocardial tissue. A system for treating cardiac arrhythmia may include a first thermal treatment device configured for placement within a heart in contact with myocardial tissue, a second thermal treatment device configured for placement in contact with pericardial tissue, an ablation energy source in communication with the first thermal treatment device, and a cooling energy source in communication with the second thermal treatment device, the cooling energy source causing the second thermal treatment device to reach a temperature insufficient for myocardial ablation when the second thermal treatment device is activated. A method of treating cardiac arrhythmia may include introducing a cooling element into a pericardial space proximate pericardial adipose tissue, and activating the cooling element to reduce the temperature of adjacent pericardial adipose tissue to approximately 0° C.

9. 发明公开

EP3119303A4 SHAPE CHANGING ABLATION BALLOON 有权
公开(公告)号：EP3119303A4
公开(公告)日：2017-11-22
申请号：EP15764746
申请日：2015-03-18
申请人： MEDTRONIC CRYOCATH LP
发明人： LALONDE JEAN-PIERRE , DAVIE SCOTT W
IPC分类号： A61B18/00 , A61B18/02 , A61B18/14 , A61M25/10
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00255 , A61B2018/00375 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： A device, method, and system for thermally affecting tissue. The device may generally include an elongate body, an actuation element slidably disposed within the elongate body, a balloon defining an interior chamber, a proximal neck, and a distal neck, the first neck being coupled to the distal portion of the elongate body and the second neck being coupled to the distal portion of the actuation element, retraction of the actuation element within the elongate body causing the treatment element to transition from a first configuration to a second configuration. The distal neck may be located external to the interior chamber in the first configuration and within the interior chamber in the second configuration. The device may also include a fluid injection element that is transitionable to an expanded configuration when the balloon is inflated, thereby enhancing the cooling capacity of the balloon.

10. 发明公开

EP3119303A1 SHAPE CHANGING ABLATION BALLOON 有权
标题翻译： FORMVERNDNDERNDER ABLATIONSBALLON
公开(公告)号：EP3119303A1
公开(公告)日：2017-01-25
申请号：EP15764746.2
申请日：2015-03-18
申请人： Medtronic Cryocath LP
发明人： LALONDE, Jean-Pierre , DAVIE, Scott W.
IPC分类号： A61B18/02 , A61M25/10
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00255 , A61B2018/00375 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： A device, method, and system for thermally affecting tissue. The device may generally include an elongate body, an actuation element slidably disposed within the elongate body, a balloon defining an interior chamber, a proximal neck, and a distal neck, the first neck being coupled to the distal portion of the elongate body and the second neck being coupled to the distal portion of the actuation element, retraction of the actuation element within the elongate body causing the treatment element to transition from a first configuration to a second configuration. The distal neck may be located external to the interior chamber in the first configuration and within the interior chamber in the second configuration. The device may also include a fluid injection element that is transitionable to an expanded configuration when the balloon is inflated, thereby enhancing the cooling capacity of the balloon.
摘要翻译：用于热影响组织的装置，方法和系统。该装置通常可以包括细长主体，可滑动地设置在细长主体内的致动元件，限定内部腔室，近端颈部和远端颈部的气囊，第一颈部联接到细长主体的远端部分，第二颈部联接到致动元件的远侧部分，致动元件在细长体内缩回，使得治疗元件从第一构型转变到第二构型。远端颈部可以位于第一构造的内部腔室的外部并且在第二构造中位于内部腔室内。该装置还可以包括流体注射元件，当气囊膨胀时，流体注入元件可转变成膨胀构型，从而增强气囊的冷却能力。

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