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1. 发明授权

EP0724750B1 METHOD FOR UNSUPERVISED NEURAL NETWORK CLASSIFICATION WITH BACK PROPAGATION 失效
标题翻译：背部传播监督分类程序神经网络
公开(公告)号：EP0724750B1
公开(公告)日：2000-03-01
申请号：EP94930805.0
申请日：1994-10-17
申请人： Miles, Inc.
发明人： ORNSTEIN, Leonard
IPC分类号： G06F15/80
CPC分类号： G06K9/6267 , G06N3/088 , Y10S128/925

2. 发明公开

EP0670849A4 DIAGNOSTIC ASSAY FOR LATENT MATRIX METALLOPROTEINASE NO. 9. 失效
标题翻译：诊断测试SPEZIFISCHFÜRDIE LATENTE MATRIX METROOPROTEINASE NO。 9。
公开(公告)号：EP0670849A4
公开(公告)日：1996-10-02
申请号：EP94900437
申请日：1993-10-28
申请人： MILES INC
发明人： AHRENS DIANE , NIEDBALA MICHAEL J
IPC分类号： C07K16/40 , C07K15/28 , G01N33/541 , G01N33/543 , G01N33/573 , G01N33/577
CPC分类号： C07K16/40
摘要： Disclosed are methods of detecting levels of pro-MMP-9, which is a latent form 92 kDa gelatinase, and pro-MMP-9/TIMP-1 complexes in plasma. The methods are useful as a diagnostic assay for rheumatoid and inflammatory arthritis and inflammatory bowel disease.
摘要翻译：公开了检测血浆中潜在形式的92kDa明胶酶和pro-MMP-9 / TIMP-1复合物的原MMP-9水平的方法。该方法可用作类风湿炎和炎性肠炎的诊断测定。

3. 发明公开

EP0724750A1 METHOD FOR UNSUPERVISED NEURAL NETWORK CLASSIFICATION WITH BACK PROPAGATION 失效
标题翻译：背部变无监督神经网络分类程序
公开(公告)号：EP0724750A1
公开(公告)日：1996-08-07
申请号：EP94930805.0
申请日：1994-10-17
申请人： Miles, Inc.
发明人： ORNSTEIN, Leonard
IPC分类号： G06N3
CPC分类号： G06K9/6267 , G06N3/088 , Y10S128/925
摘要： An unsupervised back propagation method for training neural networks. For a set of inputs, target outputs are assigned 1's and 0's randomly or arbitrarily for a small number of outputs. The learning process is initiated and the convergence of outputs towards targets is monitored. At intervals, the learning is paused, and the values for those targets for the outputs which are converging at a less than average rate, are changed (e.g., 0 → 1, or 1 → 0), and the learning is then resumed with the new targets. The process is continuously iterated and the outputs converge on a stable classification, thereby providing unsupervised back propagation. In a further embodiment, samples classified with the trained network may serve as the training sets for additional subdivisions to grow additional layers of a hierarchical classification tree which converges to indivisible branch tips. After training is completed, such a tree may be used to classifiy new unlabelled samples with high efficiency. In yet another embodiment, the unsupervised back propagation method of the present invention may be adapted to classify fuzzy sets.

4. 发明公开

EP0683602A1 Method and apparatus for a low noise, charge coupled device 失效
标题翻译： Verfahren und Vorrichtungfüreinegeräuscharmeladungsgekoppelte Anordnung。
公开(公告)号：EP0683602A1
公开(公告)日：1995-11-22
申请号：EP95104482.5
申请日：1995-03-27
申请人： MILES INC.
发明人： Pandelaers, Patrick M. , Buyze, Johan S.
IPC分类号： H04N3/15
CPC分类号： H04N5/3592 , H01L27/14831
摘要： The control voltages of a charge coupled device (CCD) are set to induce a small amount of bias charge in the photogate region. This charge serves to bias the device so that it operates with low noise in a linear fashion, especially when exposed to low radiation levels. Since the bias is produced electrically rather than optically, the noise level of the CCD is reduced. Low radiation levels are offset to higher light levels which are in a more linear portion of the device characteristic.
摘要翻译：电荷耦合器件（CCD）的控制电压被设置为在光栅区域中引起少量的偏置电荷。该电荷用于偏置器件，使得其以线性方式以低噪声工作，特别是当暴露于低辐射水平时。由于偏压是电气而不是光学产生的，所以CCD的噪声水平降低。低辐射水平被偏移到更高的光水平，其在装置特性的更线性部分。

5. 发明公开

EP0637961A4 METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE WITH LEUKOTRIENE SYNTHESIS INHIBITORS. 失效
标题翻译：的炎性肠道疾病WITH的处理方法抑制剂白三烯的合成。
公开(公告)号：EP0637961A4
公开(公告)日：1995-08-09
申请号：EP94909751
申请日：1994-02-18
申请人： MILES INC
发明人： MARSHALL PAUL J , WOOD DAVID D , NICKERSON-NUTTER CHERYL L , MULLER-PEDDINGHAUS REINER
IPC分类号： A61K31/47 , A61P1/12
CPC分类号： A61K31/47 , Y10S514/925

6. 发明公开

EP0663615A2 Dual media buffer with over-running clutch system 失效
标题翻译： Zweimedien Puffer mit einem Freilaufkupplungssystem。
公开(公告)号：EP0663615A2
公开(公告)日：1995-07-19
申请号：EP94120416.6
申请日：1994-12-22
申请人： MILES INC. (an Indiana corporation)
发明人： Krupica, Libor , Austin, Peter , Kelley, Edward L.
IPC分类号： G03D13/00 , B65H43/00
CPC分类号： H04N1/0032 , G03D13/003 , H04N1/00127 , H04N1/00567 , H04N1/0057 , H04N1/00591 , H04N1/00602 , H04N1/00618 , H04N1/00657 , H04N1/00679 , H04N2201/0063
摘要： A dual buffer (10) internal to an imaging device (14) uses a one-way, over-running clutch system to buffer multiple sheets of media between an internal drum recorder (24) and a processor. The one-way over-running clutch system is incorporated into a drive system (20, 22) of a plurality of rollers (32a, 46a) that transport the media. An input set of rollers (32a) and an output set of rollers (46b) are driven independently to allow for two sheets (I1, I2) of media to be buffered simultaneously and at different speeds if desired. The buffer (10) is mounted pivotally within the imaging device (14) to allow access into the imaging device and to allow installation of a take-up cassette (98) as an alternative to the buffer (10).
摘要翻译：成像装置（14）内部的双缓冲器（10）使用单向超行程离合器系统来缓冲内部鼓式记录器（24）和处理器之间的多张介质。单向超跑离合器系统被并入传送介质的多个辊（32a，46a）的驱动系统（20,22）中。独立地驱动输入的一组辊（32a）和一组输出的辊（46b），以允许两个片（I1，I2）的介质同时被缓冲并且如果需要的话以不同的速度。缓冲器（10）枢转地安装在成像装置（14）内，以允许进入成像装置并且允许安装作为缓冲器（10）的替代的卷取盒（98）。

7. 发明授权

EP0345549B1 Removal of protein A from antibody preparations 有权
标题翻译：从抗体制剂A蛋白的去除。
公开(公告)号：EP0345549B1
公开(公告)日：1995-04-26
申请号：EP89109455.9
申请日：1989-05-25
申请人： MILES INC.
发明人： Bloom, James W. , Wong, Melvin F. , Mitra, Gautam
IPC分类号： C07K1/18 , C07K16/00 , G01N33/68
CPC分类号： G01N33/6842 , C07K16/065 , C07K16/36 , G01N33/68

8. 发明授权

EP0508119B1 Novel process for the preparation of amine-terminated compounds 失效
标题翻译：一种用于在具有氨基端基的化合物的制备方法。
公开(公告)号：EP0508119B1
公开(公告)日：1995-04-19
申请号：EP92103960.8
申请日：1992-03-09
申请人： MILES INC.
发明人： Yeater, Robert P. , Mafoti, Robson , Sanders, Josef
IPC分类号： C07C227/08 , C07C229/30
CPC分类号： C08G63/916 , C07C227/08 , C08G65/3255 , C08G65/332 , C08G65/3322 , C08G65/333

9. 发明授权

EP0402699B1 Chromogenic dibenzoxazepinone and dibenzothiazepinone enzyme substrates 失效
标题翻译：显色的二苯并氧氮杂酮和二苯并硫氮杂酮底物
公开(公告)号：EP0402699B1
公开(公告)日：1995-02-22
申请号：EP90110198.0
申请日：1990-05-30
申请人： MILES INC.
发明人： Corey, Paul F.
IPC分类号： C07H15/26 , C07H17/00 , C12Q1/34
CPC分类号： C07F9/6536 , C07D267/18 , C07D281/14 , C07F9/6527 , C07H17/00 , C12Q1/34 , C12Q2334/00 , G01N2333/924

10. 发明公开

EP0618546A1 Method for determining color boundaries for correcting for plate misregistration in color printing 失效
标题翻译：一种用于分色的确定方法为表面印刷版的配准不良的用于彩色打印的校正。
公开(公告)号：EP0618546A1
公开(公告)日：1994-10-05
申请号：EP94104903.3
申请日：1994-03-29
申请人： MILES INC.
发明人： Dermer, Richard A. , Reifenstein, III Edward C.
IPC分类号： G06K15/00 , H04N1/46
CPC分类号： G06K15/00 , H04N1/58
摘要： A method for determining the boundaries between regions of color making up polychromatic document pages or images, in order to compensate for misregistration of printing plates in printing, and thereby to prevent light leaks and other errors at the boundaries so determined. A map of the boundaries is generated, to which trapping operations are applied to form a structured graphic object that is included as the last object imaged in the data representing the original image. The geometrical description of the boundary map determined according to the method of the invention is independent of specific trapping decisions applicable to the associated image.

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