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1. 发明授权

EP2991767B1 PIPETTE WASH 无效转让
公开(公告)号：EP2991767B1
公开(公告)日：2018-12-12
申请号：EP14791217.4
申请日：2014-05-01
申请人： Douglas Scientific, LLC
发明人： SMITH, Chad Steven , HENDRICKX, Jacob , MISCHE, Hans A.
IPC分类号： B01L99/00 , B08B9/02 , B01L3/02 , B08B9/032 , G01N35/10
CPC分类号： B01L99/00 , B01L3/0275 , B01L2400/049 , B08B9/0323 , G01N35/1004
摘要： A method of washing an array of pipette tips (94) with residual biological material includes lowering the array of pipette tips (94) into a wash basin (20) that includes an array of flush ports (22). A vacuum is generated such that the residual biological material in the array of pipette tips (94) is evacuated through the array of flush ports (22). A wash cycle is performed that includes raising the array of pipette tips (94) from the wash basin (20), filling the wash basin (20) with a primary wash fluid, lowering the array of pipette tips (94) into the wash basin (20), miming a pipette tip cleansing cycle, and generating a vacuum such that the primary wash fluid in the array of pipette tips (94) and the wash basin (20) is evacuated through the array of flush ports (22).

2. 发明授权

EP2972408B1 WASH THROUGH PIPETTOR 有权转让
公开(公告)号：EP2972408B1
公开(公告)日：2019-04-17
申请号：EP14762494.4
申请日：2014-03-14
申请人： Douglas Scientific, LLC
发明人： SCHOENECK, Richard J. , WAGNER, Paul H.
IPC分类号： G01N35/10 , G01N1/14 , B01L3/02

3. 发明公开

EP2991767A4 PIPETTE WASH 无效转让
标题翻译： PIPETTENWASCHUNG
公开(公告)号：EP2991767A4
公开(公告)日：2016-12-28
申请号：EP14791217
申请日：2014-05-01
申请人： DOUGLAS SCIENT LLC
发明人： SMITH CHAD STEVEN , HENDRICKX JACOB , MISCHE HANS A
IPC分类号： B01L99/00 , B01L3/02 , B08B9/02 , B08B9/032 , G01N35/10
CPC分类号： B01L99/00 , B01L3/0275 , B01L2400/049 , B08B9/0323 , G01N35/1004
摘要： A method of washing an array of pipette tips (94) with residual biological material includes lowering the array of pipette tips (94) into a wash basin (20) that includes an array of flush ports (22). A vacuum is generated such that the residual biological material in the array of pipette tips (94) is evacuated through the array of flush ports (22). A wash cycle is performed that includes raising the array of pipette tips (94) from the wash basin (20), filling the wash basin (20) with a primary wash fluid, lowering the array of pipette tips (94) into the wash basin (20), miming a pipette tip cleansing cycle, and generating a vacuum such that the primary wash fluid in the array of pipette tips (94) and the wash basin (20) is evacuated through the array of flush ports (22).

4. 发明授权

EP2313197B1 MICROPLATE AND METHODS FOR MAKING THE SAME 有权转让
标题翻译：微孔板及其制造方法
公开(公告)号：EP2313197B1
公开(公告)日：2012-05-09
申请号：EP09790439.5
申请日：2009-07-15
申请人： Douglas Machine, Inc.
发明人： PETERSON, Bruce, Malcolm
IPC分类号： B01L3/00 , B29C51/00 , B29C65/18
CPC分类号： B01L3/50851 , B01L2200/025 , B29C51/00 , B29C65/18 , B29C66/112 , B29C66/131 , B29C66/5346 , B29C66/61 , B29L2031/712 , Y10T156/1062
摘要： A microplate (10) includes a carrier (12) having a plate (20) and an annular perimeter wall (30) to define a recess (34). An array of holes (26) extends through the plate (20). A tape piece (16), die cut from a flexible tape (60) includes an array of wells (54) each extending through and having an opening (56) extending into the well (54). The array of wells (54) has a number and locations corresponding to the array of holes (26). The openings (56) have sizes corresponding to the holes (26). An upper surface (50) of the tape piece (16) is abutted with and bonded to the bottom face (24) of the plate (20) with the openings (56) corresponding to the array of holes (26). The slideable receipt of an annular outer periphery (58) of the tape piece (16) insures that the array of wells (54) are aligned to correspond to the array of holes (26) as die cutting of tape piece (16) insures that the array of wells (54) are at consistent positions relative to the annular outer periphery (58).

5. 发明授权

EP2344852B1 SCANNER PHOTOMETER HEAD AND ASSOCIATED METHOD 有权转让
公开(公告)号：EP2344852B1
公开(公告)日：2023-05-10
申请号：EP09740576.5
申请日：2009-10-09
发明人： HAQ, Adnanul , SCHOENECK, Richard J.
IPC分类号： G01J3/44 , G01N21/64 , G01J3/10 , G01J3/36

6. 发明公开

EP3969581A2 CAPTURE AND ANALYSIS OF TARGET GENOMIC REGIONS 审中-实审转让
公开(公告)号：EP3969581A2
公开(公告)日：2022-03-23
申请号：EP20806525.0
申请日：2020-05-13
申请人： Rapid Genomics LLC
发明人： NEVES, Leandro, Gomide
IPC分类号： C12N15/00 , C12N15/09 , C12N15/10 , C12N15/11

7. 发明公开

EP2943580A4 BIOLOGICAL SAMPLE ANALYTICAL INSTRUMENT 有权转让
标题翻译： ANALYSEINSTRUMENTFÜRBIOLOGISCHE PROBEN
公开(公告)号：EP2943580A4
公开(公告)日：2016-09-28
申请号：EP14737813
申请日：2014-01-13
申请人： DOUGLAS SCIENT LLC
发明人： WHALEN MARK , GERVAIS CHARLES , SANBORN ANTHONY , HAUG ANDREW , COOK DARREN , RAI SATISH , MISCHE HANS A , JUDICE STEPHEN A , SHAFFER DANIEL J
IPC分类号： C12P19/34 , B01J19/00 , B01L7/00 , C12N15/09 , C12Q1/68 , G01N21/29 , G01N30/06 , G01N35/10
CPC分类号： B01J19/0046 , B01J2219/00313 , B01J2219/00351 , B01J2219/00495 , B01J2219/00585 , B01J2219/00722 , B01L7/00 , B01L2200/142 , B01L2300/0812 , B01L2300/1822 , B01L2300/1894 , C12Q1/6846 , G01N21/6456 , G01N35/00009 , G01N2035/00356 , G01N2035/0403 , G01N2035/1034
摘要： A method for processing a biological material sample includes dispensing a sample into wells of an array tape from a sample plate, dispensing a reagent into the wells of the array tape from a reagent plate, and sealing the sample and the reagent in the array tape. The method further includes cooling the array tape and detecting biological material in the wells of the array tape.
摘要翻译：一种用于处理生物材料样品的方法包括从样品板将样品分配到阵列带的孔中，从试剂板将试剂分配到阵列带的孔中，并将样品和试剂密封在阵列带中。该方法还包括冷却阵列带并检测阵列带的孔中的生物材料。

8. 发明公开

EP2991767A1 PIPETTE WASH 无效转让
公开(公告)号：EP2991767A1
公开(公告)日：2016-03-09
申请号：EP14791217.4
申请日：2014-05-01
申请人： Douglas Scientific, LLC
发明人： SMITH, Chad Steven , HENDRICKX, Jacob , MISCHE, Hans A.
IPC分类号： B01L99/00 , B08B9/02 , B01L3/02
CPC分类号： B01L99/00 , B01L3/0275 , B01L2400/049 , B08B9/0323 , G01N35/1004
摘要： A method of washing an array of pipette tips (94) with residual biological material includes lowering the array of pipette tips (94) into a wash basin (20) that includes an array of flush ports (22). A vacuum is generated such that the residual biological material in the array of pipette tips (94) is evacuated through the array of flush ports (22). A wash cycle is performed that includes raising the array of pipette tips (94) from the wash basin (20), filling the wash basin (20) with a primary wash fluid, lowering the array of pipette tips (94) into the wash basin (20), running a pipette tip cleansing cycle, and generating a vacuum such that the primary wash fluid in the array of pipette tips (94) and the wash basin (20) is evacuated through the array of flush ports (22).
摘要翻译：用剩余生物材料清洗移液管尖端（94）阵列的方法包括将移液管尖端（94）阵列降低到包括一排冲洗端口（22）的清洗盆（20）中。产生真空，使得移液管尖端（94）阵列中的残余生物材料通过冲洗端口阵列（22）被抽空。执行洗涤循环，该循环包括从洗手盆（20）升起移液管吸头（94）阵列，用主洗涤液填充洗手盆（20），将移液管吸头（94）阵列降低到洗手盆（20），运行移液管尖端清洁循环，并产生真空，使得移液管尖端（94）和洗手盆（20）的阵列中的主要清洗流体通过冲洗端口阵列（22）被抽空。

9. 发明公开

EP3976899A1 FLEXIBLE AND HIGH-THROUGHPUT SEQUENCING OF TARGETED GENOMIC REGIONS 审中-实审转让
公开(公告)号：EP3976899A1
公开(公告)日：2022-04-06
申请号：EP20814047.5
申请日：2020-05-29
申请人： Rapid Genomics LLC
发明人： NEVES, Leandro Gomide , PAYTON, Adam
IPC分类号： E04C2/24

10. 发明公开

EP3709026A1 INSTRUMENT FOR ANALYZING BIOLOGICAL SAMPLES AND REAGENTS 有权转让
公开(公告)号：EP3709026A1
公开(公告)日：2020-09-16
申请号：EP20173320.1
申请日：2015-07-28
申请人： Douglas Scientific, LLC
发明人： COOK, Darren Lynn , JOHNSON, Eric Guy , WESTAD, Nathan Luther , HAUG, Andrew Richard , KONYNENBELT, James Henry , MAASJO, Grant Edward , PATTERSON, Jared Whittier , URKE, Brent Conrad , ZITZMANN, Ryan John , SMITH, Chad Steven
IPC分类号： G01N35/02 , B01L3/00 , G01N35/10 , G01N35/00
摘要： A dispensing assembly comprising:
a gantry with an x-axis track and a y-axis track, the y-axis track of the gantry configured to move along the x-axis track of the gantry;
a dispensing head attached to the y-axis track of the gantry below the y-axis track of the gantry, the dispensing head comprising:
a contact dispensing unit; and
a non-contact dispensing unit with a jet tip for dispensing a liquid;
a dispensing enclosure attached to the y-axis track of the gantry on top of the y-axis track of the gantry, the dispensing enclosure having a pressure reservoir; and
a tube connecting the jet tip of the non-contact dispensing unit to the pressure reservoir of the dispensing enclosure;

wherein the contact dispensing unit is attached to the y-axis track of the gantry with a first z-axis track; and
wherein the non-contact dispensing unit is attached to the contact dispensing unit with a second z-axis track.

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