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1. 发明公开

EP2370124A1 SYSTEM FOR ENRICHING A BODILY FLUID WITH A GAS HAVING OCCLUSION DETECTION CAPABILITIES 审中-公开
标题翻译：系统ZUR ANREICHERUNG EINERKÖRPERFLÜSSIGKEITMIT EINEM GAS MITOKKLUSIONSNACHWEISFÄHIGKEIT
公开(公告)号：EP2370124A1
公开(公告)日：2011-10-05
申请号：EP09765187.1
申请日：2009-11-24
申请人： TherOx, Inc.
发明人： MYRICK, Stephen , WATSON, Gregory
IPC分类号： A61M1/32
CPC分类号： A61M1/32 , A61M1/3643 , A61M1/3644 , A61M2202/0476 , A61M2205/12 , B01F3/04758
摘要： This invention discloses a modular system having a base module (1000), a mid-section control module (2000), and a display module (3000) for preparing and administering a gas-enriched bodily fluid via an extracorporeal circuit. Gas-enrichment is achieved by a gas-enriching device (2100) which can be in the form of a disposable cartridge. During operation, the gas-enrichment device is placed in an enclosure (2050) within the control module. An electronic controller (2080) manages the various aspects of the system such as the production of gas-enriched fluid, flow rates, bubble detection, and automatic operation and shut down. The controller is capable of detecting occlusions in the extracorporeal circuit and responding to different occlusion conditions to prevent forced shutdown/re-priming of the circuit.
摘要翻译：本发明公开了一种具有基座模块，中段控制模块和显示模块的模块化系统，用于通过体外电路制备和施用富含气体的体液。气体富集通过可以是一次性药筒形式的气体富集装置实现。在操作期间，气体浓缩装置被放置在控制模块内的外壳中。电子控制器管理系统的各个方面，例如生产富含气体的流体，流量，气泡检测和自动操作和关闭。该控制器能够检测体外电路中的闭塞并响应不同的闭塞状态以防止电路的强制关闭/再起动。

2. 发明公开

EP2387425A1 METHOD AND DEVICE FOR COMBINED DETECTION OF BUBBLES AND FLOW RATE IN A SYSTEM FOR ENRICHING A BODILY FLUID WITH A GAS 审中-公开
标题翻译：方法和装置联合检测气泡和流量在系统中用于体液油气富集
公开(公告)号：EP2387425A1
公开(公告)日：2011-11-23
申请号：EP09764951.1
申请日：2009-11-24
申请人： TherOx, Inc.
发明人： MYRICK, Stephen , WATSON, Gregory , CREECH, Jeffrey
IPC分类号： A61M1/16 , A61M1/36
CPC分类号： A61M1/3626 , A61M1/1698 , A61M1/3621 , A61M2205/3331 , A61M2205/3375
摘要： This invention discloses a modular system having a base module (1000), a mid-section control module (2000), and a display module (3000) for preparing and administering a gas-enriched bodily fluid. Gas -enrichment is achieved by a gas-enriching device (2100) which can be in the form of a disposable cartridge. During operation, the gas-enrichment device is placed in an enclosure within the control module. An electronic controller manages the various aspects of the system such as the production of gas-enriched fluid, flow rates, bubble detection, and automatic operation and shut down. The system includes a combination bubble detector/flow meter (2060) that uses a single ultrasonic probe for detecting bubbles and measuring fluid flow rate.

3. 发明公开

EP2370123A2 SYSTEM FOR ENRICHING A BODILY FLUID WITH A GAS HAVING AUTOMATED PRIMING CAPABILITIES 有权
标题翻译：系统富集体液与自动PRIMINGEIGENSCHAFTEN气体
公开(公告)号：EP2370123A2
公开(公告)日：2011-10-05
申请号：EP09764649.1
申请日：2009-11-24
申请人： TherOx, Inc.
发明人： MYRICK, Stephen , WATSON, Gregory , GILKERSON, John , AOKI, John
IPC分类号： A61M1/32
CPC分类号： A61M1/32 , A61M2205/123 , A61M2209/08 , B01F3/04758
摘要： This invention discloses a modular system having a base module, a mid-section control module, and a display module for preparing and administering a gas-enriched bodily fluid. Gas-enrichment is achieved by a gas-enriching device which can be in the form of a disposable cartridge. During operation, the gas-enrichment device is placed in an enclosure within the control module to form a fluid pathway for extracorporeal circulation of the bodily fluid. An electronic controller manages the various aspects of the system and executes an automated method for priming the extracorporeal circuit.

4. 发明公开

EP2370122A1 SYSTEM FOR ENRICING A BODILY FLUID WITH A GAS HAVING A DUAL-FUNCTION POWER SWITCH MECHANISM 审中-公开
标题翻译： SYSTEM FOR与DOUBLE设有电源开关机构与燃气体液富集
公开(公告)号：EP2370122A1
公开(公告)日：2011-10-05
申请号：EP09764412.4
申请日：2009-11-24
申请人： TherOx, Inc.
发明人： MYRICK, Stephen , WATSON, Gregory , YOUNG, Achilles
IPC分类号： A61M1/16 , A61M1/32
CPC分类号： A61M1/32
摘要： This invention discloses a modular system having a base module, a mid-section control module, and a display module for preparing and administering a gas-enriched bodily fluid. An apparatus adapted for connecting with a gas tank is included in the system for gas tank hook-up. Gas-enrichment is achieved by a gas-enriching device which can be in the form of a disposable cartridge. During operation, the gas-enrichment device is placed in an enclosure within the control module. An electronic controller manages the various aspects of the system such as the production of gas-enriched fluid, flow rates, bubble detection, and automatic operation and shut down. The system has a power supply for providing electrical power to the system, and a switching mechanism coupled to the power supply and gas tank for synchronized switching of the power supply and the gas tank between an ON state and an OFF state.

5. 发明授权

EP2370123B1 SYSTEM FOR ENRICHING A BODILY FLUID WITH A GAS HAVING AUTOMATED PRIMING CAPABILITIES 有权
标题翻译：系统富集体液与自动PRIMINGEIGENSCHAFTEN气体
公开(公告)号：EP2370123B1
公开(公告)日：2013-05-29
申请号：EP09764649.1
申请日：2009-11-24
申请人： TherOx, Inc.
发明人： MYRICK, Stephen , WATSON, Gregory , GILKERSON, John , AOKI, John
IPC分类号： A61M1/32
CPC分类号： A61M1/32 , A61M2205/123 , A61M2209/08 , B01F3/04758

6. 发明公开

EP2387426A1 SYSTEM FOR ENRICHING A BODILY FLUID WITH A GAS HAVING A REMOVABLE GAS-ENRICHMENT DEVICE WITH AN INFORMATION RECORDING ELEMENT 审中-公开
标题翻译： SYSTEM FOR体液与气体有可拆卸油气富集装置与具有信息记录元素富集
公开(公告)号：EP2387426A1
公开(公告)日：2011-11-23
申请号：EP09799208.5
申请日：2009-11-24
申请人： TherOx, Inc.
发明人： MYRICK, Stephen , WATSON, Gregory , CREECH, Jeffrey , AOKI, John
IPC分类号： A61M1/32 , A61M1/36
CPC分类号： A61M1/32 , A61M2202/0208 , A61M2202/0476 , A61M2205/60
摘要： This invention discloses a modular system having a base module (1000), a mid-section control module (2000), and a display module (3000) for preparing and administering a gas-enriched bodily fluid via an extracorporeal circuit. Gas-enrichment is achieved by a gas-enriching device (2100) which can be in the form of a disposable cartridge. The gas-enrichment device has an information recording element disposed thereon. During operation, the gas -enrichment device is placed in an enclosure within the control module. An electronic controller manages the various aspects of the system such as the production of gas-enriched fluid, flow rates, bubble detection, and automatic operation and shut down. The controller is capable of setting a fluid flow rate in the circuit according to a programming based on the information encoded in the information recording element.

7. 发明授权

EP1599392B1 SYSTEM FOR STORING AND DISPENSING A GAS-SOLUBILIZED PRODUCT 有权
标题翻译： SYSTEM FOR保存和分配在气体产品解决
公开(公告)号：EP1599392B1
公开(公告)日：2007-12-05
申请号：EP04714116.3
申请日：2004-02-24
申请人： TherOx, Inc.
发明人： GILKERSON, John , CREECH, Jeffrey , HSU, Li-Chien , WATSON, Gregory
IPC分类号： B65D83/14
CPC分类号： A61K8/046 , A61K8/22 , A61K8/70 , A61K2800/88 , A61Q19/00 , B65D83/62
摘要： A packaged gas-solubilized product is described. The gas-solubilized product contains a first gas with a first pressure. The product is placed into a flexible inner container (2) made of a gas-impermeable material. The inner container is hermetically disposed inside an outer container (1). A space (4) formed between the inner and the outer containers is charged with a second gas with an initial charging pressure. The initial charging pressure is higher than the pressure of the first gas contained in the product. Additionally, a product dispenser (3) in a fluid connection with the product contained in the internal container is included. The present invention also provides a method of packaging a gas-solubilized product to prevent a change in the concentration of the gas dissolved in the product during its storage and dispensing.

8. 发明公开

EP1599392A1 SYSTEM FOR STORING AND DISPENSING A GAS-SOLUBILIZED PRODUCT 有权
标题翻译： SYSTEM FOR保存和分配在气体产品解决
公开(公告)号：EP1599392A1
公开(公告)日：2005-11-30
申请号：EP04714116.3
申请日：2004-02-24
申请人： Therox, Inc.
发明人： GILKERSON, John , CREECH, Jeffrey , HSU, Li-Chien , WATSON, Gregory
IPC分类号： B65D83/14
CPC分类号： A61K8/046 , A61K8/22 , A61K8/70 , A61K2800/88 , A61Q19/00 , B65D83/62
摘要： A packaged gas-solubilized product is described. The gas-solubilized product contains a first gas with a first pressure. The product is placed into a flexible inner container (2) made of a gas-impermeable material. The inner container is hermetically disposed inside an outer container (1). A space (4) formed between the inner and the outer containers is charged with a second gas with an initial charging pressure. The initial charging pressure is higher than the pressure of the first gas contained in the product. Additionally, a product dispenser (3) in a fluid connection with the product contained in the internal container is included. The present invention also provides a method of packaging a gas-solubilized product to prevent a change in the concentration of the gas dissolved in the product during its storage and dispensing.

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