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    • 2. 发明公开
    • CIRCUMFERENTIAL ABLATION DEVICE ASSEMBLY AND METHOD
    • 环形消融装置组件和方法
    • EP1009303A1
    • 2000-06-21
    • EP98933279.6
    • 1998-07-08
    • The Regents of the University of CaliforniaAtrionix, Inc.EMORY UNIVERSITY
    • DIEDERICH, Chris, J.LESH, Michael, D.PEACOCK, James, C., IIIROSS, Michael, RonaldLANGBERG, Jonathan, J.
    • A61B17/39A61N5/04A61N7/02A61B17/38
    • A61B18/10A61B5/0464A61B18/08A61B18/1492A61B18/18A61B18/1815A61B2017/22038A61B2018/00065A61B2018/00083A61B2018/00107A61B2018/00148A61B2018/00214A61B2018/0022A61B2018/00351A61B2018/00375A61B2018/00577A61B2018/00642A61B2018/1407A61M25/1002A61M2025/1047A61M2025/1052A61M2025/1068A61M2025/1075A61M2210/125A61N7/02A61N7/022
    • A circumferential ablation device assembly includes a circumferential ablation member with an ablation element that is adapted to ablate a circumferential region of tissue in the region of a pulmonary vein ostium. The ablation element couples to a middle portion of the circumferential ablation member and which is bordered on either side by two end portions. The end portions are adapted to shield and thereby isolate ablative energy from the ablation element to the circumferential region of tissue adjacent the middle region. The ablation element is coupled to an expandable member with a working length that is adjustable to a radially expanded position which engages the circumferential region of tissue, and may be coupled only to a narrow circumferential band that circumscribes the outer surface of the working length to form the middle region adapted to ablate tissue adjacent thereto. The ablation element may couple to the entire working length of the expandable member, and insulators may be provided over both end portions to leave the circumferential band as the only ablative middle region. The expandable member conforms to the pulmonary vein ostium, such as by providing a great deal of radial compliance or by providing a taper along the working length with a distally reducing outer diameter. The ablation element may be any energy sink adapted to couple to and ablate the circumferential region, although in one mode an ultrasound transducer is ultrasonically coupled to the circumferential band to either heat the band or pass through the band in order to ablate the circumferential region of tissue. A linear ablation element is provided adjacent to the ablation element in a combination assembly which is adapted for use in a less-invasive 'maze'-type procedure in the region of the pulmonary vein ostia in the left atrium.
    • 周缘消融装置组件包括具有消融元件的周缘消融元件,该消融元件适于消融肺静脉口区域中的组织的周缘区域。 消融元件耦合到周缘消融构件的中间部分,并且在两侧由两个端部部分界定。 末端部分适于屏蔽并从而将消融元件的消融能量隔离到邻近中间区域的组织的圆周区域。 消融元件联接到具有工作长度的可扩张构件,该工作长度可调节到接合组织周边区域的径向扩展位置,并且可仅联接到外接工作长度的外表面的窄周向带,以形成 中间区域适于消融与其相邻的组织。 消融元件可以耦合到可膨胀构件的整个工作长度,并且绝缘体可以设置在两个末端部分上以使周缘带作为唯一的消融中间区域。 可扩张构件符合肺静脉口,例如通过提供大量的径向顺应性或通过沿着工作长度提供具有远侧减小的外径的锥形。 消融元件可以是适于耦合并消融周边区域的任何能量汇,尽管在一种模式中,超声换能器超声耦合到周缘带以加热带或穿过带以便消融周缘区 组织。 在组合组件中邻近消融元件提供线性消融元件,该组合组件适用于在左心房的肺静脉口的区域中的微创“迷宫”型过程。