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1. 发明公开

EP3973939A1 COMPOSITION FOR MONONUCLEAR CELL-CONTAINING PLASMA SEPARATION AND BLOOD SAMPLING CONTAINER 审中-实审转让
公开(公告)号：EP3973939A1
公开(公告)日：2022-03-30
申请号：EP20809540.6
申请日：2020-05-19
申请人： Sekisui Medical Co., Ltd. , Tokuyama Sekisui Co., Ltd.
发明人： KOMAI, Kuniya , ISOGAWA, Hironobu , ANRAKU, Hideo
IPC分类号： A61J1/05 , G01N33/48
摘要： Provided is a composition for mononuclear cell-containing plasma separation capable of suppressing a flow of the composition for mononuclear cell-containing plasma separation during storage, capable of satisfactorily forming a partition during centrifugation, and capable of yielding mononuclear cell-containing plasma with little admixture of blood cell components other than mononuclear cells. The composition for mononuclear cell-containing plasma separation according to the present invention contains an organic component having fluidity at 25°C and two or more kinds of inorganic fine powders, and has a specific gravity of 1.060 or more and 1.080 or less at 25°C.

2. 发明公开

EP2410329A1 COMPOSITION FOR PLASMA AND SERUM SEPARATION, AND CONTAINER FOR BLOOD TESTING 有权
标题翻译： ZUSAMMENSETZUNG ZUR PLASMA- UND SERUMSTRENNUNG SOWIEBLUTTESTBEHÄLTER
公开(公告)号：EP2410329A1
公开(公告)日：2012-01-25
申请号：EP11747115.1
申请日：2011-01-25
申请人： Sekisui Medical Co., Ltd.
发明人： ANRAKU, Hideo , NIUNOYA, Masatoshi
IPC分类号： G01N33/48 , C08K3/00 , C08L71/02
CPC分类号： G01N33/491 , C08G2650/58 , C08L71/02 , Y10T137/794 , Y10T436/106664 , Y10T436/25
摘要： The invention provides a serum or plasma separating composition which can compensate for the lack of initial thixotropy even at a reduced inorganic powder concentration and in which crevices or the like are less likely to be created in a partition wall formed of the separating composition after being centrifuged. The serum or plasma separating composition contains a liquid resin component having a partition wall-forming capability, a hydrophilic inorganic powder, a hydrophobic inorganic powder, and an organic compound serving as a thixotropy enhancer, wherein the organic compound is a polyalkylene glycol and/or a derivative thereof and is made of at least one type of polymer selected from the group consisting of: 1) a homopolymer of a single type of monomer selected from C 3 to C 5 alkylene oxide monomers; 2) a random copolymer, an altering copolymer, or a periodic copolymer of two or more types of monomers selected from C 2 to C 5 alkylene oxide monomers; 3) a block copolymer of two or more types of monomers selected from C 3 to C 5 alkylene oxide monomers; and 4) a graft copolymer of at least one type of polymer selected from the polymers 1) to 3), the polyalkylene glycol and/or the derivative thereof has a number average molecular weight of 500 to 100000, both inclusive, and the content of the polyalkylene glycol and/or the derivative thereof in the total amount of the serum or plasma separating composition is 0.2% to 5% by weight, both inclusive.
摘要翻译：本发明提供血清或血浆分离组合物，其即使在降低的无机粉末浓度下也可补偿初始触变性的缺乏，并且在离心后在分离组合物形成的分隔壁中不太可能产生裂缝等。血清或血浆分离组合物含有具有分隔壁形成能力的液体树脂组分，亲水性无机粉末，疏水性无机粉末和用作触变增强剂的有机化合物，其中有机化合物是聚亚烷基二醇和/或其衍生物由至少一种选自以下的聚合物制成：1）选自C 3至C 5烯化氧单体的单一类型单体的均聚物; 2）选自C 2至C 5烯化氧单体的两种或更多种类型的单体的无规共聚物，改变共聚物或周期共聚物; 3）选自C 3至C 5环氧烷单体的两种或更多种类型的单体的嵌段共聚物; 和4）选自聚合物1）至3）中的至少一种类型的聚合物的接枝共聚物，所述聚亚烷基二醇和/或其衍生物的数均分子量为500〜100000，其含量为血清或血浆分离组合物的总量中的聚亚烷基二醇和/或其衍生物的含量为0.2重量％〜5重量％。

3. 发明公开

EP3309547A1 SERUM- OR PLASMA-SEPARATING COMPOSITION, BLOOD-TEST CONTAINER, AND METHOD OF STABILIZING SERUM- OR PLASMA-SEPARATING COMPOSITION 有权
标题翻译：血清或血浆分离组合物，血液测试容器和稳定血浆或血浆分离组合物的方法
公开(公告)号：EP3309547A1
公开(公告)日：2018-04-18
申请号：EP16807557.0
申请日：2016-06-09
申请人： Sekisui Medical Co., Ltd.
发明人： ANRAKU, Hideo , OKAMOTO, Ryusuke
IPC分类号： G01N33/48
CPC分类号： G01N33/491 , B01L3/5082 , C08L65/00 , C08L2205/03 , C08L2207/04 , G01N33/48
摘要： There is provided a serum- or plasma-separating composition less likely to cause separation between a liquid organic compound and a thixotropy imparting component and capable of maintaining a homogeneous blended state for a prolonged period. The serum- or plasma-separating composition comprises a liquid organic compound, a thixotropy imparting component, and a thermoplastic elastomer.
摘要翻译：提供了不易引起液体有机化合物和触变性赋予成分之间分离并且能够长时间保持均匀混合状态的血清或血浆分离组合物。血清或血浆分离组合物包含液体有机化合物，触变性赋予组分和热塑性弹性体。

4. 发明授权

EP2410329B1 COMPOSITION FOR PLASMA AND SERUM SEPARATION, AND CONTAINER FOR BLOOD TESTING 有权
标题翻译：成分血浆和血清分离血液检查集装箱
公开(公告)号：EP2410329B1
公开(公告)日：2014-10-01
申请号：EP11747115.1
申请日：2011-01-25
申请人： Sekisui Medical Co., Ltd.
发明人： ANRAKU, Hideo , NIUNOYA, Masatoshi
IPC分类号： G01N33/48 , C08K3/00 , C08L71/02 , G01N33/49 , G01N33/50
CPC分类号： G01N33/491 , C08G2650/58 , C08L71/02 , Y10T137/794 , Y10T436/106664 , Y10T436/25

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