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1. 发明授权

EP2579922B1 DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 失效
公开(公告)号：EP2579922B1
公开(公告)日：2016-11-16
申请号：EP11724221.4
申请日：2011-06-09
申请人： Sanofi-Aventis Deutschland GmbH
发明人： SMITH, Christopher, James , BUTLER, Stephen, David , HORLOCK, Mark, Philip
IPC分类号： A61M5/24 , A61M5/315
CPC分类号： A61M5/31528 , A61M5/31543 , A61M5/31555 , A61M5/31585

2. 发明授权

EP2579927B1 DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 有权
公开(公告)号：EP2579927B1
公开(公告)日：2018-02-21
申请号：EP11724421.0
申请日：2011-06-09
申请人： Sanofi-Aventis Deutschland GmbH
发明人： BUTLER, Stephen, David , HORLOCK, Mark, Philip
IPC分类号： A61M5/315
CPC分类号： A61M5/31528 , A61M5/31535 , A61M5/31548 , A61M5/3155 , A61M5/31551 , A61M5/31555 , A61M5/31583 , A61M5/31585 , A61M5/31593 , F16H25/12 , Y10T74/18576
摘要： The drive mechanism comprises a drive member inside a housing, a rotation member and a dose member. The drive member is rotatable with respect to the housing. The rotation member is also rotatable and unidirectionally rotationally engaged with the drive member. The dose member is able to move along a set/deliver path between a first axial position and a second axial position in either direction or to move along a cancel path from the second axial position to the first axial position. An engagement of the dose member with the rotation member causes the rotation member to rotate when the dose member is moved along the set/deliver path. The drive member is not rotated when the dose member is moved along the cancel path. A button in/out spline can be provided for the set/deliver path and a cancel spline for the cancel path.

3. 发明授权

EP2579928B1 DRIVE ASSEMBLY, DRIVE COMPONENT AND DRUG DELIVERY DEVICE 有权
标题翻译：驱动组件，驱动组件和药物递送装置
公开(公告)号：EP2579928B1
公开(公告)日：2017-10-11
申请号：EP11724422.8
申请日：2011-06-09
申请人： Sanofi-Aventis Deutschland GmbH
发明人： SMITH, Christopher, James , BUTLER, Stephen, David , HORLOCK, Mark, Philip
IPC分类号： A61M5/315
CPC分类号： A61M5/31551 , A61M5/142 , A61M5/31536 , A61M5/31555 , A61M5/31585 , A61M2205/581 , A61M2205/582 , F16H19/02 , Y10T74/18568
摘要： A drive assembly (70) for a drug delivery device (1) comprises a rotation member (21) being configured to be rotated in a first direction (44) during setting of a dose of a drug and to be rotated in a second direction (47) during delivery of the dose, a drive component (20) being configured to follow rotational movement of the rotation member (21) in the second direction (47) during delivery of the dose and a stop member (26) being configured to prevent rotational movement of the drive component (20) in the first direction (44). The drive component (20) comprises a first drive part (71) and a second drive part (72), coupled to each other such that relative rotational movement of the first and second drive parts (71, 72) is prevented and relative axial movement is permitted.

4. 发明公开

EP2854908A1 DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 无效
标题翻译：控制机构的积极释放设备部署和释放装置
公开(公告)号：EP2854908A1
公开(公告)日：2015-04-08
申请号：EP13725658.2
申请日：2013-05-28
申请人： Sanofi-Aventis Deutschland GmbH
发明人： BUTLER, Stephen, David , HORLOCK, Mark, Philip
IPC分类号： A61M5/315
CPC分类号： A61M5/31543 , A61M5/24 , A61M5/3155 , A61M5/31555 , A61M5/31561 , A61M5/31585 , A61M5/31593 , A61M2005/2407
摘要： The drive mechanism for a drug delivery device comprises a piston rod, which is displaced in a distal direction for a delivery of a dose and in a proximal direction for a reset, and a rotatable drive member, which is threadedly engaged with the piston rod and rotates during the delivery of the dose. A biasing member is provided, which is loaded by the rotation of the drive member during the delivery of the dose and tends to rotate the piston rod with respect to the drive member in such a way that the piston rod is screwed into the drive member and is thereby advanced in the proximal direction. The drug delivery device is provided with such a drive mechanism.

5. 发明授权

EP2579920B1 ASSEMBLY FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 有权
公开(公告)号：EP2579920B1
公开(公告)日：2019-07-31
申请号：EP11724218.0
申请日：2011-06-09
申请人： Sanofi-Aventis Deutschland GmbH
发明人： RAAB, Steffen , HORLOCK, Mark, Philip , BUTLER, Stephen, David
IPC分类号： A61M5/24 , A61M5/315

6. 发明公开

EP2579925A1 MEDICATION DELIVERY DEVICE 有权
标题翻译：药物计费装置
公开(公告)号：EP2579925A1
公开(公告)日：2013-04-17
申请号：EP11725715.4
申请日：2011-06-09
申请人： Sanofi-Aventis Deutschland GmbH
发明人： SMITH, Christopher, James , HEALD, Michael , BUTLER, Stephen, David , HORLOCK, Mark, Philip
IPC分类号： A61M5/24 , A61M5/315
CPC分类号： A61M5/24 , A61M5/31543 , A61M5/31555 , A61M5/31585
摘要： A medication delivery device (1) is provided which is switchable between an operational state and a resetting state and which comprises a housing (13) having a proximal end (8) and a distal end (7), a piston rod (12) being moveable in a distal direction with respect to the housing (13) for medication delivery, a conversion element (38) adapted to at least partially convert a rotational movement of the piston rod (12) into an axial movement of the piston rod (12), coupling means (39) prevented from rotational movement with respect to the housing (13) and adapted to engage with the conversion element (38) in the operational state, a drive assembly (3) comprising at least two drive assembly members and adapted for moving the piston rod (12) in the distal direction, and a resilient member (31) adapted to provide a force on the drive assembly (3) for engagement of the drive assembly members. In the operational state of the device (1) the coupling means (39) is engaged with the conversion element (38), the conversion element (38) thereby being prevented from rotation with respect to the housing (13). In the resetting state of the device (1) the coupling means (39) is disengaged from the conversion element (38) under force of the resilient member (31), the conversion element (38) thereby being allowed to rotate with respect to the housing (13) and thereby allowing a resetting of the device (1).

7. 发明公开

EP2579921A1 DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE 有权
标题翻译：控制机构的积极释放设备
公开(公告)号：EP2579921A1
公开(公告)日：2013-04-17
申请号：EP11724220.6
申请日：2011-06-09
申请人： Sanofi-Aventis Deutschland GmbH
发明人： RAAB, Steffen , SMITH, Christopher, James , HORLOCK, Mark, Philip , BUTLER, Stephen, David
IPC分类号： A61M5/24 , A61M5/315
CPC分类号： A61M5/31543 , A61M5/24 , A61M5/3155 , A61M5/31551 , A61M5/31553 , A61M5/31555 , A61M5/3158 , A61M5/31583 , A61M5/31585
摘要： A drive mechanism for a drug delivery device which can be switched between a normal operation state and a reset state comprises of a housing having a proximal end and a distal end, a rotation member which is adapted to rotate in a first direction and in a second direction with respect to the housing, a drive member, wherein in the normal operation state the rotation member is coupled with the drive member so that the drive member follows rotational movement of the rotation member in the second direction, a piston rod, wherein in the normal operation state the piston rod is displaced in a distal direction with respect to the housing when the drive member rotates in the second direction with respect to the housing, a stop member, wherein in the normal operation state the stop member is coupled with the drive member so that the stop member prevents rotational movement of the drive member with respect to the housing in the first direction, and a separation member for switching the operation state, the separation member being adapted to move the stop member and the drive member in the distal direction with respect to the housing when the normal operation state is switched to the reset state, thereby decoupling the stop member and the drive member and decoupling the drive member and the rotation member.

8. 发明授权

EP2854908B1 DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 无效
公开(公告)号：EP2854908B1
公开(公告)日：2018-03-21
申请号：EP13725658.2
申请日：2013-05-28
申请人： Sanofi-Aventis Deutschland GmbH
发明人： BUTLER, Stephen, David , HORLOCK, Mark, Philip
IPC分类号： A61M5/24 , A61M5/315
CPC分类号： A61M5/31543 , A61M5/24 , A61M5/3155 , A61M5/31555 , A61M5/31561 , A61M5/31585 , A61M5/31593 , A61M2005/2407
摘要： The drive mechanism for a drug delivery device comprises a piston rod, which is displaced in a distal direction for a delivery of a dose and in a proximal direction for a reset, and a rotatable drive member, which is threadedly engaged with the piston rod and rotates during the delivery of the dose. A biasing member is provided, which is loaded by the rotation of the drive member during the delivery of the dose and tends to rotate the piston rod with respect to the drive member in such a way that the piston rod is screwed into the drive member and is thereby advanced in the proximal direction. The drug delivery device is provided with such a drive mechanism.

9. 发明公开

EP2579928A1 DRIVE ASSEMBLY, DRIVE COMPONENT AND DRUG DELIVERY DEVICE 有权
标题翻译：控制装置，控制装置和主动释放装置
公开(公告)号：EP2579928A1
公开(公告)日：2013-04-17
申请号：EP11724422.8
申请日：2011-06-09
申请人： Sanofi-Aventis Deutschland GmbH
发明人： SMITH, Christopher, James , BUTLER, Stephen, David , HORLOCK, Mark, Philip
IPC分类号： A61M5/315
CPC分类号： A61M5/31551 , A61M5/142 , A61M5/31536 , A61M5/31555 , A61M5/31585 , A61M2205/581 , A61M2205/582 , F16H19/02 , Y10T74/18568
摘要： A drive assembly (70) for a drug delivery device (1) comprises a rotation member (21) being configured to be rotated in a first direction (44) during setting of a dose of a drug and to be rotated in a second direction (47) during delivery of the dose, a drive component (20) being configured to follow rotational movement of the rotation member (21) in the second direction (47) during delivery of the dose and a stop member (26) being configured to prevent rotational movement of the drive component (20) in the first direction (44). The drive component (20) comprises a first drive part (71) and a second drive part (72), coupled to each other such that relative rotational movement of the first and second drive parts (71, 72) is prevented and relative axial movement is permitted.

10. 发明公开

EP2579927A1 DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 有权
标题翻译：一种药物递送装置和药物递送装置的驱动机构
公开(公告)号：EP2579927A1
公开(公告)日：2013-04-17
申请号：EP11724421.0
申请日：2011-06-09
申请人： Sanofi-Aventis Deutschland GmbH
发明人： BUTLER, Stephen, David , HORLOCK, Mark, Philip
IPC分类号： A61M5/315
CPC分类号： A61M5/31528 , A61M5/31535 , A61M5/31548 , A61M5/3155 , A61M5/31551 , A61M5/31555 , A61M5/31583 , A61M5/31585 , A61M5/31593 , F16H25/12 , Y10T74/18576
摘要： The drive mechanism comprises a drive member inside a housing, a rotation member and a dose member. The drive member is rotatable with respect to the housing. The rotation member is also rotatable and unidirectionally rotationally engaged with the drive member. The dose member is able to move along a set/deliver path between a first axial position and a second axial position in either direction or to move along a cancel path from the second axial position to the first axial position. An engagement of the dose member with the rotation member causes the rotation member to rotate when the dose member is moved along the set/deliver path. The drive member is not rotated when the dose member is moved along the cancel path. A button in/out spline can be provided for the set/deliver path and a cancel spline for the cancel path.
摘要翻译：驱动机构包括壳体（17）内的驱动构件（20），旋转构件（21）和剂量构件（34）。驱动构件相对于壳体可旋转。旋转构件也可旋转并且与驱动构件单向旋转地接合。剂量构件能够在任一方向上沿第一轴向位置和第二轴向位置之间的设定/传送路径移动或沿着从第二轴向位置到第一轴向位置的取消路径移动。当剂量构件沿着设定/传送路径移动时，剂量构件与旋转构件的接合引起旋转构件旋转。当剂量构件沿取消路径移动时，驱动构件不旋转。可以为设定/传送路径提供按钮输入/输出样条（52），为取消路径提供取消样条（53）。

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