专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP1018514A1 NF-$g(k)B INHIBITORS CONTAINING INDAN DERIVATIVES AS THE ACTIVE INGREDIENT 有权
标题翻译： NF-KAPPA B抑制剂，DIE INDANDERIVATE ALS AKTIVEN BESTANDTEIL ENTHALTEN
公开(公告)号：EP1018514A1
公开(公告)日：2000-07-12
申请号：EP99931496.6
申请日：1999-07-22
申请人： SUNTORY LIMITED
发明人： NUNOKAWA, Yoichi , NAKATSUKA, Takashi , SAITOH, Masayuki , ABE, Keiichi
IPC分类号： C07D473/34 , C07D487/04 , C07D491/048 , C07D495/04 , C07D498/04 , C07D513/04 , A61K31/505 , A61K31/52 , C07C271/24 , C07C269/06
CPC分类号： C07D487/04 , C07D473/34 , C07D491/04 , C07D495/04 , C07D513/04
摘要： An inhibitor of NF-κB comprising as an active ingredient an indan derivative represented by the general formula (I) or a salt thereof.
摘要翻译：含有由通式（I）表示的茚满衍生物或其盐作为活性成分的NF-κB抑制剂。

2. 发明公开

EP1008346A1 NF-$g(k)B INHIBITORS CONTAINING AS THE ACTIVE INGREDIENT PHENYLMETHYL BENZOQUINONE 有权
标题翻译： BENZOCHINONDERIVATE ENTHALTENDE HEMMER VON NF-kB
公开(公告)号：EP1008346A1
公开(公告)日：2000-06-14
申请号：EP99909284.4
申请日：1999-03-19
申请人： SUNTORY LIMITED
发明人： NUNOKAWA, Yoichi , SUZUKI, Kenji , SAITOH, Masayuki
IPC分类号： A61K31/12 , A61K31/165 , A61K31/19 , A61K31/245 , A61K31/335 , A61K31/36 , A61K31/40 , A61K31/44 , A61K31/445 , A61K31/495 , A61K31/535 , A61K31/54 , A61K31/55 , C07C66/00 , C07C235/78 , C07D207/04 , C07D211/16 , C07D211/22 , C07D211/32 , C07D211/42 , C07D211/46
CPC分类号： C07D319/18 , A61K31/00 , A61K31/12 , A61K31/122 , A61K31/165 , A61K31/19 , A61K31/245 , A61K31/335 , A61K31/36 , A61K31/40 , A61K31/44 , A61K31/445 , A61K31/495 , A61K31/535 , A61K31/54 , A61K31/55 , C07C50/28 , C07C235/78 , C07C2601/18 , C07D207/08 , C07D207/10 , C07D211/22 , C07D211/60 , C07D213/74 , C07D215/08 , C07D223/10 , C07D295/185 , C07D317/66 , A61K2300/00
摘要： NF-kB inhibitors containing as the active ingredient benzoquinone derivatives represented by general formula (I), hydroquinone compounds thereof or salts of the same, wherein R 1 , R 2 and R 3 independently represent each H, C 1-5 alkyl or C 1-5 alkoxy; R 4 represents H, hydroxy-methyl, alkyl or optionally esterified or amidated carboxy; Z is represented by formula (A); and n is from 0 to 6.
摘要翻译：含有作为活性成分的通式（I）表示的苯醌衍生物的NF-kB抑制剂，其氢醌化合物或其盐，其中R 1，R 2和R 3各自独立地表示H，C 1-5烷基或C 1-5烷氧基; R4表示H，羟基 - 甲基，烷基或任选酯化或酰胺化的羧基; Z由式（A）表示; 且n为0至6.

3. 发明公开

EP0798304A1 REMEDIES FOR THROMBOCYTOPENIA 失效
标题翻译：治疗血栓形成的补救措施
公开(公告)号：EP0798304A1
公开(公告)日：1997-10-01
申请号：EP96935352.3
申请日：1996-10-17
申请人： SUNTORY LIMITED
发明人： SAITOH, Masayuki , KITAJIMA, Yasuo , IWASAWA, Norio , MIURA, Kenju , HARUYAMA, Munetada , HASHINO, Junko
IPC分类号： C07F9/655 , A61K31/665
CPC分类号： C07F9/6552
摘要： Compounds represented by the general formula (I) or pharmacologically acceptable salts thereof:
(where R is a group -NHCHR 1 R 2 , -N(CHR 1 R 2 ) 2 , -N(CHR 1 R 2 )CHR 3 R 4 , -N + (CHR 1 R 2 ) 3 , -N + (CHR 1 R 2 ) 2 CHR 3 R 4 or -N + (CHR 1 R 2 )(CHR 3 R 4 )CHR 5 R 6 (where R 1 , R 2 , R 3 , R 4 , R 5 and R 6 , which may be the same or different, are each a hydrogen atom, an alkyl group, an alkenyl group, an aryl group or an aralkyl group, or an alkyl, alkenyl, aryl or aralkyl group which is substituted by at least one substituent selected from the group consisting of a halogen atom, a hydroxyl group, a lower alkoxy group, a lower alkylacyloxy group, a lower alkylacyl group, a lower alkoxycarbonyl group, a nitro group, a cyano group and a heterocyclic group, with CHR 1 R 2 , CHR 3 R 4 or CHR 5 R 6 optionally forming a cyclic alkyl group, provided that when R is -N(CHR 1 R 2 )CHR 3 R 4 , -N + (CHR 1 R 2 ) 2 CHR 3 R 4 or -N + (CHR 1 R 2 )(CHR 3 R 4 )CHR 5 R 6 , CHR 1 R 2 , CHR 3 R 4 and CHR 5 R 6 are different groups); therapeutics for thrombocytopenia containing them as an effetive ingredient; as well as intermediates for their synthesis and processes for producing them.
摘要翻译：（I）表示的化合物或其药理学上可接受的盐：（其中R为基团-NHCHR1R2，-N（CHR1R2）2，-N（CHR1R2）CHR3R4，-N +（CHR1R2）3，-N +（CHR1R2） 2 CHR3R4或-N +（CHR1R2）（CHR3R4）CHR5R6（其中R1，R2，R3，R4，R5和R6可以相同或不同，各自为氢原子，烷基，链烯基，芳基或芳烷基，或被至少一个选自卤素原子，羟基，低级烷氧基，低级烷基氧基，低级烷基酰氧基，低级烷酰氧基，（CHR 1 R 2）CHR 3 R 4，-N +（CHR 1 R 2）2 CHR 3 R 4，其中当R为-N 或-N +（CHR1R2）（CHR3R4）CHR5R6，CHR1R2，CHR3R4和CHR5R6是不同的基团）;含有它们作为有效成分的血小板减少症的治疗剂;作为以及它们的合成中间体和生产它们的过程。

4. 发明授权

EP0798304B1 REMEDIES FOR THROMBOCYTOPENIA 失效
标题翻译：治疗血栓形成的补救措施
公开(公告)号：EP0798304B1
公开(公告)日：2003-03-12
申请号：EP96935352.3
申请日：1996-10-17
申请人： SUNTORY LIMITED
发明人： SAITOH, Masayuki , KITAJIMA, Yasuo , IWASAWA, Norio , MIURA, Kenju , HARUYAMA, Munetada , HASHINO, Junko
IPC分类号： C07F9/655 , A61K31/665
CPC分类号： C07F9/6552

5. 发明公开

EP0668289A1 NOVEL DISACCHARIDE DERIVATIVE 失效
标题翻译：异物衍生物
公开(公告)号：EP0668289A1
公开(公告)日：1995-08-23
申请号：EP94909291.0
申请日：1994-03-09
申请人： SUNTORY LIMITED
发明人： KODAMA, Tohru , SAITOH, Masayuki , OGAWA, Tomohiko
IPC分类号： C07H11/04 , A61K31/715 , C12P19/26
CPC分类号： C07H13/06 , C07H3/04
摘要： A novel disaccharide derivative represented by chemical formula (I), stereochemical isomers and salts thereof, and a pharmaceutical composition containing the same as the active ingredient. The compound has various biological activities such as potent mitogenic activity, adjuvant activity, polyclonal B-cell activating (nonspecific protective) activity, natural killer activity, antitumor activity and antiviral activity, but scarcely has the activity of inducing the production of so-called inflammatory cytokines, such as tumor necrotizing factor (TNF) and IL-1, from macrophages unlike the lipid A and derivatives thereof. Therefore, it is free from noxious effects in which the lipid A and derivatives thereof have been problematic, such as lethal toxicity and pyrogenicity, and hence it is useful not only as immunopotentiator, antitumor agent and antiviral agent, but also as a therapeutic or preventive agent for sepsis, rheumatoid arthritis, and so forth.
摘要翻译：由化学式（I）表示的新型二糖衍生物，其立体化学异构体及其盐，以及含有该活性成分的药物组合物。该化合物具有多种生物活性，如有效的促有丝分裂活性，佐剂活性，多克隆B-细胞活化（非特异性保护）活性，自然杀伤活性，抗肿瘤活性和抗病毒活性，但几乎不具有诱导所谓炎症细胞因子，如来自巨噬细胞的肿瘤坏死因子（TNF）和IL-1，与脂质A及其衍生物不同。因此，没有脂质A及其衍生物具有致命毒性和致热原性等有害的有害作用，因此不仅用作免疫增强剂，抗肿瘤剂和抗病毒剂，而且作为治疗或预防剂败血症药物，类风湿关节炎等。

6. 发明授权

EP0721944B1 IMIDAZOLIDINE DERIVATIVE AND USE THEREOF 失效转让
标题翻译：咪唑衍生物及其
公开(公告)号：EP0721944B1
公开(公告)日：2001-01-17
申请号：EP95926500.0
申请日：1995-07-26
申请人： SUNTORY LIMITED
发明人： FUKAMI, Harukazu , SUMIDA, Motoo , NIWATA, Shinjiro , KAKUTANI, Saki , SAITOH, Masayuki , SHIBATA, Hiroshi , KISO, Yoshinobu
IPC分类号： C07D233/80 , C07D233/86 , A61K31/415 , A61K31/495 , C07D233/84 , C07D405/12 , C07D403/12 , C07D403/04 , C07D401/04
CPC分类号： C07D401/04 , C07D233/80 , C07D233/86 , C07D403/04 , C07D405/12
摘要： An imidazolidine derivative represented by general formula (1) and medicines containing the derivative as the active ingredient, representative examples of which include a chymase inhibitor and a preventive or remedy for cardiac and circulatory diseases caused by abnormal palpitation induced by angiotensin II, wherein A and B represent each an aromatic hydrocarbon group which may be substituted by one to three substituents selected from among halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 alkylenedioxy, phenoxy, nitro, cyano, phenyl, C2-C5 alkanoylamino, carboxyl which may be esterified with C1-C4 alkyl or alkenyl, carboxyalkyl which may be esterified with C1-C4 alkyl or alkenyl, carboxyalkyloxy which may be esterified with C1-C4 alkyl or alkenyl, N-alkylpiperazinylcarbonyl, N-alkylpiperazinylcarbonylalkyl, N-alkyl-piperazinylcarbonylalkyloxy and morpholinocarbonyl; X represents sulfonyl or carbonyl; and Y represents oxygen or sulfur.

7. 发明公开

EP1955586A1 PLANT CULTIVATING UNIT AND PLANT CULTIVATING CONTAINER 审中-公开
标题翻译：植物栽培单元和植物栽培容器
公开(公告)号：EP1955586A1
公开(公告)日：2008-08-13
申请号：EP06833444.0
申请日：2006-11-28
申请人： SUNTORY LIMITED
发明人： HASHIMOTO, Masaki c/o SUNTORY LIMITED , MIYAGAWA, Katsuro , SAITOH, Masayuki
IPC分类号： A01G9/02 , A01G9/04 , A01G27/00
CPC分类号： A01G9/045 , A01G9/022 , A01G9/033 , A01G27/00 , A01G31/02 , Y02A30/254 , Y02B80/32 , Y02P60/216
摘要： An object of the present invention is to provide a plant cultivating unit that can perform a watering operation in a simple manner and can supply water uniformly to plants in locations where a floor surface is sloped, such as the rooftop of a building, without requiring separate water supply piping work. A plant cultivating unit (1) comprises a water storage tray (2) in which water can be stored and in which receivers (3) for housing the roots of plants can be arranged in an interior thereof, a water storage space (8) in the water storage tray (2) and the receivers (3) being communicated via water feeders (7), and the water stored in the water storage space (8) being able to be supplied to the plants via the water feeders (7). The water storage tray (2) is provided with connectors (6) capable of communicably connecting adjacent water storage trays (2) to each other, the connectors (6) being configured from an inflow connector (6a) and an outflow connector (6b), the water flowing in through the inflow connector (6a) to the water storage space (8), and the water being able to flow out through the outflow connector (6b) by an overflow when a specific amount of water is stored in the water storage space (8).
摘要翻译：本发明的目的是提供一种植物栽培单元，其能够以简单的方式执行浇水操作，并且能够在诸如建筑物的屋顶的地面倾斜的位置的植物上均匀地供应水，而不需要单独供水管道工程。一种植物栽培单元（1）包括：储水盘（2），其中可以储存水，并且其中容纳植物根部的接收器（3）可以布置在其内部;储水空间（8），储水盘2和储存器3通过给水器7连通，储存在储水空间8中的水可以通过给水器7供给植物。在储水盘2上设置有能够将相邻的储水托盘2彼此连通的连接器6，该连接器6由流入连接器6a和流出连接器6b构成，，当通过流入连接器（6a）流入储水空间（8）的水流入水中时，当特定量的水储存在水中时，水能够通过溢流流出流出连接器（6b）存储空间（8）。

8. 发明公开

EP0721944A1 IMIDAZOLIDINE DERIVATIVE AND USE THEREOF 失效转让
标题翻译：咪唑衍生物及其
公开(公告)号：EP0721944A1
公开(公告)日：1996-07-17
申请号：EP95926500.0
申请日：1995-07-26
申请人： SUNTORY LIMITED
发明人： FUKAMI, Harukazu , SUMIDA, Motoo , NIWATA, Shinjiro , KAKUTANI, Saki , SAITOH, Masayuki , SHIBATA, Hiroshi , KISO, Yoshinobu
IPC分类号： C07D233/80 , C07D233/86 , A61K31/415 , A61K31/495
CPC分类号： C07D401/04 , C07D233/80 , C07D233/86 , C07D403/04 , C07D405/12
摘要： The invention relates to an imidazolidine derivative represented by the following general formula (1):

wherein A and B mean individually an aromatic hydrocarbon group which may be substituted by 1-3 substituents selected from halogen atoms, C 1-4 alkyl groups, C 1-4 alkoxy groups, C 1-4 alkylenedioxy groups, a phenoxy group, a nitro group, a cyano group, a phenyl group, C 2-5 alkanoylamino groups, a carboxyl group which may be esterified with a C 1-4 alkyl or alkenyl group, carboxyalkyl groups which may be esterified with a C 1-4 alkyl or alkenyl group, carboxyalkyloxy groups which may be esterified with a C 1-4 alkyl or alkenyl group, N-alkylpiperazinylcarbonyl groups, N-alkylpiperazinylcarbonylalkyl groups, N-alkylpiperazinylcarbonylalkyloxy groups, and a morpholinocarbonyl group; X denotes a sulfonyl or carbonyl group; and Y stands for an oxygen or sulfur atom, a chymase inhibitor comprising the same as an active ingredient, and a medicine comprising the same as an active ingredient, typified by a prophylactic and therapeutic agent for a disease of the heart or circulatory system, which is caused by the abnormal acceleration of production of angiotensin II.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式