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    • 2. 发明公开
    • Fungicidal isoquinoline derivatives
    • Fungizide Isochinolinderivate。
    • EP0491441A1
    • 1992-06-24
    • EP91203316.4
    • 1991-12-16
    • SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.
    • Bissinger, Hans-JoachimSchröder, LudwigAlbert, GuidoPees, Klaus-Jürgen
    • C07D217/16C07D217/22A01N43/42C07D217/14C07D491/04
    • C07D401/10A01N43/42A01N43/90C07D217/02C07D217/14C07D217/16C07D217/22C07D491/04
    • The invention provides a method of combating fungus at a locus which comprises treating the locus with a compound of the general formula

      or an N-alkyl or N-phenyl halide or N-oxide thereof, in which R¹, R², R³ and R⁴ independently represent a hydrogen or halogen atom, a hydroxyl group or an optionally substituted alkyl or alkoxy group, or R¹ and R² or R² and R³ or R³ and R⁴ together with the interjacent carbon atoms represent a 5- to 7-membered saturated or unsaturated carbocyclic or heterocyclic ring in which a heterocyclic ring contains 1 to 3 heteroatoms selected from nitrogen, oxygen and sulphur atoms; R⁵ represents a hydrogen or halogen atom, R⁶ represents a hydrogen atom, or R⁵ and R⁶ together represent a single carbon- carbon bond; R⁷ represents a hydrogen or halogen atom, an alkyl or alkoxy group optionally substituted by one or more halogen atoms, or an optionally substituted phenyl or phenoxy group; R⁸ and R⁹ independently represent a hydrogen atom or together represent a single carbon-carbon bond; and A represents an optionally substituted phenyl group. Certain of the isoquinoline derivatives are novel and a process for the preparation of these compounds and compositions containing them are also provided.
    • 本发明提供了一种抗病原菌的方法,该方法包括用通式为CHEM的化合物或N-烷基或N-苯基卤化物或其N-氧化物处理所述场所,其中R 1,R R 3和R 4独立地表示氢或卤素原子,羟基或任意取代的烷基或烷氧基,或R 1和R 2或R 2和R 3或R 3和R 4与中间碳原子一起代表5-至7-元饱和或不饱和的碳环或杂环,其中杂环含有1-3个选自氮,氧和 硫原子; R 5表示氢或卤素原子,R 6表示氢原子,或R 5和R 6共同表示单个碳 - 碳键; R 7表示氢或卤素原子,任选被一个或多个卤素原子取代的烷基或烷氧基,或任选取代的苯基或苯氧基; R 8和R 9独立地表示氢原子或一起代表单个碳 - 碳键; 并且A表示任选取代的苯基。 某些异喹啉衍生物是新颖的,还提供了制备这些化合物的方法和含有它们的组合物。
    • 5. 发明公开
    • Herbicidal picolinamide derivatives
    • Herbizide Picolinamidderivate。
    • EP0537816A1
    • 1993-04-21
    • EP92202760.2
    • 1992-09-10
    • SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.
    • Bissinger, Hans-JoachimKleemann, AxelSearle, Richard John Griffith
    • C07D213/81C07D213/84A01N43/40
    • C07D213/81A01N43/40C07D213/84
    • Compounds of the formula:

      wherein R₁ and R₂ each independently represents hydrogen, optionally substituted alkyl, aryl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, aralkyl, alkaryl, hydroxy, alkoxy, alkenyloxy, alkynyloxy, alkylcarbonyl, alkoxycarbonyl, amino, mono- or di-alkylamino, alkoxycarbonylamino, optionally substituted heterocycle or arylamino, dialkylcarbamoyl, trialkylsilyl or fused ring structure, or together form an alkenylene chain or an alkylene chain which is optionally interrupted by oxygen or sulphur or -NR-, R being hydrogen or alkyl; R₃ represents hydrogen or halogen, or optionally substituted alkyl, alkoxy, aryl or aryloxy, or cyano, carboxy, alkoxycarbonyl, (alkylthio)carbonyl, alkylcarbonyl, amido, alkylamido, nitro, alkenyloxy, alkynyloxy, alkylthio, haloalkylthio, alkenylthio, alkynylthio, alkylsulphinyl, alkylsulphonyl, alkyloximinoalkyl or alkenyloximinoalkyl; R₄ represents halogen, alkyl or haloalkyl; Z represents oxygen or sulphur; m is 0-3; and n is 1-4, and certain intermediates in their production, exhibit herbicidal activity.
    • 其中R 5和R 6各自独立地表示氢,任选取代的烷基,芳基,烯基,炔基,环烷基,环烷基烷基,芳烷基,烷芳基,羟基,烷氧基,烯氧基,炔氧基,烷基羰基 ,烷氧基羰基,氨基,单 - 或二 - 烷基氨基,烷氧基羰基氨基,任选取代的杂环或芳基氨基,二烷基氨基甲酰基,三烷基甲硅烷基或稠环结构,或一起形成亚烯基链或亚烷基链,任选被氧或硫或-NR- R为氢或烷基; R 7表示氢或卤素,或任选取代的烷基,烷氧基,芳基或芳氧基或氰基,羧基,烷氧基羰基,(烷硫基)羰基,烷基羰基,酰氨基,烷基酰氨基,硝基,烯氧基,炔氧基,烷硫基,卤代烷硫基,烯硫基, 炔基硫代,烷基亚磺酰基,烷基磺酰基,烷基肟基烷基或烯基肟基烷基; R 8表示卤素,烷基或卤代烷基; Z表示氧或硫; m为0-3; n为1-4,某些中间体在其生产中具有除草活性。