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    • 1. 发明公开
    • DISPOSITIF DE JONCTION ÉTANCHE POUR LE TRANSFERT ASEPTIQUE D'UN PRODUIT BIOPHARMACEUTIQUE ENTRE UNE ENCEINTE ET UN CONTENEUR
    • 紧连接器移转给生物制药的ASEPTISCEN
    • EP2736639A1
    • 2014-06-04
    • EP12744091.5
    • 2012-07-12
    • SARTORIUS STEDIM FMT SAS
    • NODIN, GaëlleGIBELIN, Jérémy
    • B01L1/02G21F7/005
    • B01L1/02C12M37/04G21F7/005
    • Leaktight joining device for the aseptic transfer of a biopharmaceutical product between a chamber and a container. The invention relates to the field of the aseptic transfer of biopharmaceutical products between a container and a closed chamber. More specifically, the invention relates, according to a first aspect, to a leaktight joining device (40) for ensuring the aseptic transfer of a biopharmaceutical product between a chamber (10) equipped with a removable door (18) and a container (20) equipped with a removable cover (28), comprising: stationary temporary flanging means (50), stationary unlocking means (60) capable of changing the container (20) from an initial locking position to an intermediate unlocking position so as to ensure an aseptic communication between said container (20) and said chamber (10), stationary locking means (70) capable of changing the container (20) from the intermediate unlocking position to a final locking position, an annular functional ring gear (42) capable of actuating the stationary unlocking means (60) and the stationary locking means (70) of the container (20). According to the invention, the stationary temporary flanging means (50), the stationary unlocking means (60) and the stationary locking means (70) are mechanically linked to the annular functional ring gear (42) and arranged so that the unidirectional rotation of said annular functional ring gear (42) about the geometric axis of rotation (R) successively drives the actuation thereof.