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1. 发明公开

EP2282213A1 Sample preparation dosing unit 审中-公开
标题翻译：样品制备剂量单位
公开(公告)号：EP2282213A1
公开(公告)日：2011-02-09
申请号：EP09167174.3
申请日：2009-08-04
申请人： F. Hoffmann-La Roche AG , Roche Diagnostics GmbH
发明人： Holenstein, Tobias , Engel, Thomas , Sidler, Thomas , Zuppiger, Adelrich , Haack, Carsten , D'Amore, Alessandro , Meyberg, Michael , Greuter, Tobias , Stoeckli, Roland
IPC分类号： G01N35/08
CPC分类号： G01N35/10 , G01N1/38 , G01N35/08 , G01N35/1002 , G01N35/1065 , Y10T137/0318 , Y10T137/85978
摘要： The invention is directed towards a sample preparation dosing unit for liquid dosing, comprising:
a) an inlet port (5) for fluidically coupling the sample preparation dosing unit to the supply (7)
b) an outlet port (10) for fluidically coupling the sample preparation dosing unit to the target,
b) a pump (15), fluidically arranged between the inlet port (5) and the outlet port (10),
c) an outlet flow restrictor (20) with an outlet flow resistance, fluidically arranged between an outlet of the pump (15) and the outlet port (10),
d) a control arrangement with a branch (17), a control valve (25, 26) and a control flow restrictor (30) with a control flow resistance, such that
• the flow at the outlet of the pump (15) is divided by the branch (17) into an outlet flow through the outlet flow restrictor (20) and into a control flow through the control flow restrictor (30), and the control flow downstream of the control flow resistor (25) is fed, in dependence of the state of the control valve (25),
• either into the outlet port (10) such that it merges with the outlet flow downstream of the outlet flow restrictor (20),
• or into a bypass conduit (35).

The sample preparation dosing unit may especially be used for preparing biological samples for medical and/or chemical analysis.
摘要翻译：本发明涉及一种用于液体配量的样品制备剂量单元，包括：a）用于将样品制备剂量单元流体连接到供应源（7）的入口端口（5）; b）用于将样品制备剂量单元样品制备剂量单元施加到目标，b）流体地布置在入口端口（5）和出口端口（10）之间的泵（15），c）具有出口流阻的出口限流器（20），流体布置在泵（15）的出口与出口端口（10）之间，d）具有分支（17），控制阀（25,26）和控制流量限制器（30）的控制装置，，使得泵（15）的出口处的流体被分支（17）分成通过出口限流器（20）的出口流和通过控制限流器（30）的控制流，并且根据控制阀的状态馈送控制流动电阻器（25）下游的控制流 e（25），或者进入出口端口（10），使其与出口流量限制器（20）下游的出口流体合流，或进入旁路导管（35）。样品制备剂量单元尤其可以用于制备用于医学和/或化学分析的生物样品。

2. 发明公开

EP2535712A1 Analytical system for the preparation of biological material 审中-公开
标题翻译：分析系统zur Herstellung eines biologischen材料
公开(公告)号：EP2535712A1
公开(公告)日：2012-12-19
申请号：EP11169994.8
申请日：2011-06-15
申请人： F. Hoffmann-La Roche AG , Roche Diagnostics GmbH
发明人： Zuppiger, Adelrich , Burghardt, Géza , Meyberg, Michael , D'Amore, Alessandro , Gut, Raphael
IPC分类号： G01N33/543 , G01N35/10
CPC分类号： G01N35/10 , G01N2035/1053 , G01N2035/1062
摘要： The present invention relates to a system for the isolation of biological material, using binding particles for the separation and/or isolation of such material.
More precisely, the present invention relates to a system for the isolation of biological material comprised in a fluid sample, said system comprising
• a separation station (1) constructed and arranged to separate and purify said biological material from said fluid sample, said separation station comprising at least one receiving vessel (2)
• a reservoir (3) containing a suspension of binding particles (4) for the isolation of said biological material
• a pipetting device (5) comprising a pipettor (6) for transferring said suspension of binding particles
• a measuring device (7) for determining the relative or absolute quantity of said binding
particles or a portion thereof within said pipettor.

The present invention further provides a method for the isolation of biological material comprised in a fluid sample.
摘要翻译：本发明涉及一种用于分离生物材料的系统，其使用用于分离和/或分离这种材料的结合颗粒。更准确地说，本发明涉及用于分离包含在流体样品中的生物材料的系统，所述系统包括分离站（1），其被构造和布置成从所述流体样品中分离和净化所述生物材料，所述分离包括至少一个接收容器（2）的储存器（3），其包含用于分离所述生物材料的结合颗粒（4）的悬浮液，移液装置（5）包括移液器（6），用于将所述用于确定所述粘合颗粒的相对或绝对量或所述移液器内的一部分的测量装置（7）的粘合颗粒悬浮液。本发明还提供了用于分离包含在流体样品中的生物材料的方法。

3. 发明公开

EP3141909A1 LABORATORY ANALYZER FOR MANUALLY HANDLING A PLURALITY OF REAGENTS AND METHOD FOR OPERATING A LABORATORY ANALYZER FOR MANUALLY HANDLING A PLURALITY OF REAGENTS 有权
标题翻译： LABORANALYSATOR手动操作处置用于操作LABORANALYSATORS试剂的各种方法和手动操作处置试剂各种
公开(公告)号：EP3141909A1
公开(公告)日：2017-03-15
申请号：EP15184242.4
申请日：2015-09-08
申请人： Roche Diagnostics GmbH , F. Hoffmann-La Roche AG
发明人： Meyberg, Michael
IPC分类号： G01N35/00 , G01N35/10
CPC分类号： G01N35/00722 , B01L3/0237 , B01L9/54 , G01N35/00623 , G01N35/1002 , G01N35/1016 , G01N2035/009 , G01N2035/0091
摘要： A laboratory analyzer (100) for manually handling a plurality of reagents is disclosed. The laboratory analyzer (100) comprises a computing device (102) comprising a display (104) for displaying a workflow of a pipetting process comprising a plurality of method steps to an operator, a pipette (106) for pipetting reagents connected to the computing device (102), a plurality of compartments (110, 112, 114, 116, 118) for receiving a plurality of reagents vessels (120, 122, 124, 126, 128) including reagents to be pipetted by means of the pipette (106), a camera (130) connected to the computing device (102), wherein the camera (130) is adapted to acquire data from a vision analysis of at least the plurality of compartments (110, 112, 114, 116, 118) during manually carrying out a pipetting process by the operator according to the workflow, wherein the computing device (102) is adapted to compare the data to target data correlated to the plurality of method steps of the workflow. Further, a method for operating a laboratory analyzer (100) for manually handling a plurality of reagents is disclosed.
摘要翻译：用于手动处理的试剂的多个实验室分析仪（100）被游离缺失盘。移液管实验室分析仪（100）包括包含一个显示器（104），用于显示一个移液过程中的操作员，包括的方法步骤的多元性到，工作流的计算设备（102）中的（106），用于连接到计算设备的移液试剂（102），隔室用于接收试剂容器（120，122，124，126，128）的一个多元化包括试剂有多个（110，112，114，116，118）由所述移液管的手段（106）被吸手动期间连接到计算设备（102），其中，所述照相机（130）适于从隔室中的至少多个一个视觉分析取得的数据（110，112，114，116，118）的照相机（130）由操作者雅丁到工作流执行移液过程，worin计算设备（102）是angepasst的数据进行比较来定位相关的工作流的方法的步骤的多个数据。此外，用于操作用于手动处理的试剂的多个实验室分析仪（100）的方法游离缺失盘。

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