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1. 发明公开

EP1635699A1 INTEGRIERTES TESTELEMENT ZUR EINMALIGEN AUFNAHME UND ANALYSE EINER ZU UNTERSUCHENDEN PROBE 有权
标题翻译：综合测试元在单一的记录和样品被求职者分析
公开(公告)号：EP1635699A1
公开(公告)日：2006-03-22
申请号：EP04739508.2
申请日：2004-06-02
申请人： Roche Diagnostics GmbH , F. HOFFMANN-LA ROCHE AG
发明人： HOENES, Joachim , MILTNER, Karl
IPC分类号： A61B5/00 , A61B5/15 , G01N33/487
CPC分类号： A61B5/1459 , A61B5/14532 , A61B5/14552 , A61B5/150022 , A61B5/150358 , A61B5/150389 , A61B5/150503 , A61B5/150572 , A61B5/150824 , A61B5/15107 , A61B5/15146 , A61B5/157 , A61B5/6848 , G01N21/03 , G01N21/6428 , G01N21/7703 , G01N2021/0325 , G01N2021/6484
摘要： The invention concerns the field of integrated systems, which comprise a test element and a lancet for drawing a sample, preferably blood, whereby said lancet can be used to make a wound in the skin opening. The blood flowing out is then directly drawn by the test element in the system, and the sample comes into contact with a reagent contained in the test element, and an optically detectable change is effected in the test field. The change in the test field is detected by means of an analysis unit, which is optically contacted to the test field via at least one light-guiding element.

2. 发明公开

EP1504116A1 VERFAHREN UND REAGENZSYSTEM MIT INAKTIVIERTEM ENZYM 审中-公开
标题翻译：方法和试剂系统灭活酶
公开(公告)号：EP1504116A1
公开(公告)日：2005-02-09
申请号：EP03752757.9
申请日：2003-05-16
申请人： F. Hoffmann-La Roche AG , Roche Diagnostics GmbH
发明人： HORN, Carina , HOENES, Joachim , KNAPPE, Wolfgang-Reinhold
IPC分类号： C12Q1/26 , C12Q1/32
CPC分类号： C12Q1/32 , C12Q1/002 , C12Q1/26 , G01N33/54353 , G01N33/54373 , Y02P20/582
摘要： The invention relates to a method and reagent system for detecting an analyte in a sample by means of an enzymatic reaction, involving the use of a detection reagent containing a coenzyme and a catalytically inactive coenzyme-binding protein.

3. 发明公开

EP1504115A1 VERFAHREN UND REAGENZSYSTEM MIT NICHT-REGENERIERBAREM ENZYM-COENZYM-KOMPLEX 审中-公开
标题翻译：方法和试剂与非再生酶辅酶COMPLEX
公开(公告)号：EP1504115A1
公开(公告)日：2005-02-09
申请号：EP03732396.1
申请日：2003-05-16
申请人： F. Hoffmann-La Roche AG , Roche Diagnostics GmbH
发明人： HORN, Carina , HOENES, Joachim , KNAPPE, Wolfgang-Reinhold
IPC分类号： C12Q1/26 , C12Q1/32
CPC分类号： C12Q1/32 , C12Q1/002 , C12Q1/26 , G01N33/54353 , G01N33/54373 , Y02P20/582
摘要： The invention relates to a method and reagent system for detecting an analyte in a sample by means of an enzymatic reaction, involving the use of an enzyme-coenzyme complex as a stoichiometric reaction partner for the analyte present in the sample.

4. 发明公开

EP1504113A2 VERFAHREN ZUR HERSTELLUNG VON POLYMERSCHICHTEN 有权转让
标题翻译：用于生产聚合物层
公开(公告)号：EP1504113A2
公开(公告)日：2005-02-09
申请号：EP03730061.3
申请日：2003-05-16
申请人： F. Hoffmann-La Roche AG , Roche Diagnostics GmbH
发明人： HORN, Carina , HOENES, Joachim , KNAPPE, Wolfgang-Reinhold
IPC分类号： C12Q1/00 , G01N33/543
CPC分类号： C12Q1/32 , C12Q1/002 , C12Q1/26 , G01N33/54353 , G01N33/54373 , Y02P20/582
摘要： The invention relates to a method for producing polymer layers on a support by the photopolymerisation of a polymerisable liquid composition. The invention also relates to a device that is suitable for producing polymer layers on a support and to a method for producing a sensor, which contains a polymer layer with an integrated indicator.

5. 发明授权

EP1578272B1 BODY FLUID TESTING DEVICE 有权
标题翻译：测试设备体液
公开(公告)号：EP1578272B1
公开(公告)日：2015-12-30
申请号：EP03789086.0
申请日：2003-11-26
申请人： Roche Diagnostics GmbH , F. Hoffmann-La Roche AG
发明人： ZIMMER, Volker , HAAR, Hans-Peter , MANSER, Maria , HOENES, Joachim , MILTNER, Karl , LIST, Hans , PACHL, Rudolf
IPC分类号： A61B5/155 , G01N33/487
CPC分类号： G01N33/48764 , A61B5/14532 , A61B5/1455 , A61B2562/0295 , B01L3/505 , B01L2200/04 , B01L2300/0812 , G01N35/00009

6. 发明公开

EP2398389A1 TESTELEMENTMAGAZIN MIT ABGEDECKTEN TESTFELDERN 有权
标题翻译：有盖的测试场测试元件杂志
公开(公告)号：EP2398389A1
公开(公告)日：2011-12-28
申请号：EP10705800.0
申请日：2010-02-12
申请人： Roche Diagnostics GmbH , F. Hoffmann-La Roche AG
发明人： HOENES, Joachim
IPC分类号： A61B5/151 , A61B5/00
CPC分类号： A61B5/15146 , A61B5/14514 , A61B5/15 , A61B5/150022 , A61B5/150297 , A61B5/150358 , A61B5/150419 , A61B5/150503 , A61B5/150572 , A61B5/15107 , A61B5/15115 , A61B5/15151 , A61B5/15161 , A61B5/15176 , A61B2562/0295 , A61B2562/242 , B01L2200/141 , B01L2300/0672 , B01L2300/0825 , Y10T29/49826
摘要： The invention relates to an analytic magazine (110) comprising at least one chamber (112) having at least one analytic agent (162). The analytic agent (162) comprises at least one test element (134) for indicating at least one analyte in a sample (182) of a bodily fluid. The test element (134) comprises at least one test field (136) having at least one test chemistry (140). The test field (136) is disposed at least partially within the chamber (112), wherein at least one wall (156) of the chamber (112) at least partially covers the test field (136) and at least partially delimits a test field area (184) accessible from the chamber (112).

7. 发明授权

EP1959834B1 GEKNICKTE LANZETTE 有权
标题翻译：扭结柳叶刀
公开(公告)号：EP1959834B1
公开(公告)日：2010-11-10
申请号：EP06829137.6
申请日：2006-11-27
申请人： Roche Diagnostics GmbH , F. Hoffmann-La Roche AG
发明人： HOENES, Joachim , DECK, Frank , HAAR, Hans-Peter , KRAEMER, Uwe , ZIMMER, Volker , HARTTIG, Herbert
IPC分类号： A61B5/151
CPC分类号： A61B5/15146 , A61B5/150022 , A61B5/150282 , A61B5/150358 , A61B5/150442 , A61B5/15113 , A61B5/15115 , A61B5/15153 , A61B5/15169 , A61B5/15171 , A61B5/15176
摘要： A device for collecting samples of body fluids is described which has at least one lancet, comprising a lancet body and a tip. The device is characterized in that the lancet includes a structure of changed stiffness, which can also be referred to as a kinked area. This structure preferably has reduced stiffness compared to the rest of the lancet body, such that the lancet is preferably kinked in this area under the action of a force. As this happens, the tip is changed in orientation with respect to the rest of the lancet body. This change of orientation is preferably out of the plane of the lancet body.

8. 发明公开

EP2245152A1 STABILISIERUNG VON DEHYDROGENASEN MIT STABILEN COENZYMEN 有权转让
公开(公告)号：EP2245152A1
公开(公告)日：2010-11-03
申请号：EP09712033.1
申请日：2009-02-19
申请人： F. Hoffmann-La Roche AG , Roche Diagnostics GmbH
发明人： HEINDL, Dieter , HORN, Carina , GAESSLER-DIETSCHE, Claudia , HOENES, Joachim
IPC分类号： C12N9/96 , C12N9/06 , C12Q1/32
CPC分类号： C12N9/0006 , C12N9/96
摘要： The present invention relates to a method for stabilizing an enzyme by storing the enzyme in the presence of a stable coenzyme. Furthermore, the present invention relates to an enzyme stabilized using a stable coenzyme and to the use thereof in test elements for detecting analytes.
摘要翻译：稳定酶，包括在稳定的辅酶的存在下储存酶。包含用稳定型辅酶稳定的酶的独立权利要求。

9. 发明公开

EP1881322A1 Bauraumoptimiertes tragbares Messsystem 失效转让
公开(公告)号：EP1881322A1
公开(公告)日：2008-01-23
申请号：EP06117422.3
申请日：2006-07-18
申请人： Roche Diagnostics GmbH , F. Hoffmann-la Roche AG
发明人： HOENES, Joachim
IPC分类号： G01N33/487 , A61B5/00
CPC分类号： G01N33/48778 , A61B5/150022 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150526 , A61B5/15113 , A61B5/15117 , A61B5/15163 , A61B5/15176 , A61B5/157 , A61B2562/0295
摘要： Es wird ein tragbares Messsystem (210) zur Analyse einer flüssigen Probe auf mindestens einen darin enthaltenen Analyten vorgeschlagen. Das tragbare Messsystem (210) weist ein feuchtigkeitsdichtes Gehäuse (212) mit einer Gehäuseinnenatmosphäre (214) auf. Das feuchtigkeitsdichte Gehäuse (212) verhindert ein Eindringen von Luftfeuchtigkeit und/oder Wasserdampf in die Gehäuseinnenatmosphäre (214). Weiterhin weist das tragbare Messsystem (210) mindestens einen in die Gehäuseinnenatmosphäre (214) eingeführten Testelementträger (216) auf. Der mindestens eine Testelementträger (216) verfügt über mindestens eine Haltestruktur (218) und mindestens ein von der mindestens einen Haltestruktur (218) gelagertes Testelement (112). Der mindestens eine Testelementträger (216) ist derart ausgestaltet, dass nach Einführen in die Gehäuseinnenatmosphäre (214) das mindestens eine Testelement (112) der Gehäuseinnenatmosphäre (214) ausgesetzt ist. Weiterhin ist ein Freigabemechanismus (228) vorgesehen, welcher mindestens ein Testelement (112) in eine Applikationsposition (230) innerhalb der Gehäuseinnenatmosphäre (214) befördern kann. In dieser Applikationsposition (230) kann die flüssige Probe auf das mindestens eine Testelement (112) aufgebracht werden.
摘要翻译：该系统具有带壳体内部空气的防潮外壳（212）（214）。防潮外壳防止空气湿度和水蒸汽渗入壳体内部空气。测试元件载体（216）可安装在壳体内部空气中。测试元件载体具有由保持结构保持的保持结构（218）和测试元件（112），用于分析液体样品。将液体样品施加在壳体内部气氛中的测试元件上。

10. 发明公开

EP3004372A1 NOVEL COMPOUNDS USEFUL FOR FRET AND METHODS RELATED THERETO 审中-公开
标题翻译： ZUGEHÖRIGEVERFAHREN上的VERBINDUNGENFÜRFRE
公开(公告)号：EP3004372A1
公开(公告)日：2016-04-13
申请号：EP14728188.5
申请日：2014-06-04
申请人： Roche Diagnostics GmbH , F. Hoffmann-La Roche AG
发明人： HEINDL, Dieter , HOENES, Joachim , HORN, Carina , MEIER, Thomas , PETRICH, Wolfgang
IPC分类号： C12Q1/00 , C12Q1/26 , G01N33/533 , G01N33/535 , G01N33/542 , G01N33/573 , G01N33/58 , C12Q1/68
CPC分类号： C07H19/207 , C12Q1/26 , G01N21/6428 , G01N33/533 , G01N33/535 , G01N33/542 , G01N33/5735 , G01N33/581 , G01N33/582 , G01N2201/062 , G01N2333/90248
摘要： The invention relates to compounds, which are useful for intramolecular fluorescence resonance energy transfer (FRET), comprising the oxidized form of a carbaNADH-based first fluorophore and a second fluorophore that is excitable at a wave-length of between 445 to 540 nm and that has an emission maximum of greater than 560 nm, and methods, kits and compositions related thereto.
摘要翻译：本发明还涉及可用于分子内荧光共振能量转移（FRET）的化合物，其包含氧化形式的基于carbaNADH的第一荧光团和第二荧光团，其波长在445至540之间是可激发的 nm，并且具有大于560nm的发射最大值，以及与其相关的方法，试剂盒和组合物。

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