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1. 发明公开

EP4364766A2 APPARATUS FOR PUMPING FLUID 审中-公开
公开(公告)号：EP4364766A2
公开(公告)日：2024-05-08
申请号：EP23219352.4
申请日：2008-04-10
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： ARNOLD, Ofer , YODFAT, Ofer , NETA, Avraham
IPC分类号： A61M5/142
CPC分类号： A61M5/14248 , A61M2005/1425220130101 , A61M2005/1426420130101 , A61M2005/1426820130101 , A61M2005/158320130101 , A61M2005/158520130101
摘要： A fluid delivery device comprising: a dispensing patch unit (10) comprising a reservoir, a driving mechanism, and a pumping mechanism; and an infusion set (50) which is configured to be connected to the dispensing patch unit (10) either directly or via a luer in order to establish communication between the dispensing patch unit (10) and a cannula (330) for subcutaneous fluid delivery, wherein the two parts of the dispensing patch unit (10) are a reusable part (100) and a disposable part (200), with the reusable part comprising the driving mechanism (120).

2. 发明公开

EP3998095A1 DEVICE FOR SUSTAINED DELIVERY OF A THERAPEUTIC FLUID 有权
公开(公告)号：EP3998095A1
公开(公告)日：2022-05-18
申请号：EP21211809.5
申请日：2007-12-20
申请人： F. Hoffmann-La Roche AG , Roche Diabetes Care GmbH
发明人： IDDAN, Gavriel J. , NETA, Avraham , YODFAT, Ofer
IPC分类号： A61M5/142 , A61M5/158 , A61M39/04
摘要： A therapeutic fluid infusion system for delivering a therapeutic fluid to a human body, the system comprising: a first assembly (20) comprising: a cradle (300) configured for adhesion to a cutaneous region of the human body, a cannula (330), and a self-sealable septum (315), wherein a distal portion of the cannula (330) is configured for subcutaneous placement within the human body and wherein the self- sealable septum (315) separates a proximal portion of the cannula (330) from an external environment; and a second assembly (10) configured for removable attachment to the first assembly (20), the second assembly (10) comprising: a pump (120), a reservoir (220) for containing a therapeutic fluid, and a connecting lumen (250) configured to penetrate the self- sealable septum (315) in order to bring the second assembly (10) in fluid communication with the first assembly (20).

3. 发明授权

EP2887918B1 AUTOMATIC DEVICE FOR TRANSFERRING FLUID 有权转让
公开(公告)号：EP2887918B1
公开(公告)日：2020-08-05
申请号：EP12751320.8
申请日：2012-08-22
申请人： F. Hoffmann-La Roche AG , Roche Diabetes Care GmbH
发明人： YODFAT, Ofer , GESCHEIT, Illai J. , GESCHEIT, Iddo
IPC分类号： A61J1/20 , A61J1/22

4. 发明授权

EP2171625B1 METHOD AND DEVICE FOR PREVENTING HYPOGLYCEMIA 有权转让
公开(公告)号：EP2171625B1
公开(公告)日：2018-10-10
申请号：EP08825970.0
申请日：2008-06-20
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： YODFAT, Ofer , RAMCHANDANI, Neesha , SHAPIRA, Gali
IPC分类号： G16H20/17 , G16H50/50
CPC分类号： A61M5/1723 , A61M5/14248 , A61M2005/14208 , A61M2005/14268 , A61M2005/1726 , A61M2205/3569 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3456 , G16H50/50
摘要： A device and a method are provided that can be used for prevention of hypoglycemia. The device for prevention of hypoglycemia comprises a module adapted for receiving a target blood glucose (TBG) level corresponding to a desired level of glucose in a patient's body during a fasting time period; a module adapted for receiving a fasting time blood glucose (BBG) level corresponding to the level of glucose in the patient's body substantially at the beginning of the fasting time period; a module adapted for receiving a first set of parameters corresponding to a medical state of the patient; a module adapted for determining a therapeutic course of action based on the levels of the TBG, BBG and the medical state of the patent; and, a module adapted for administering the therapeutic course of action to the patient.

5. 发明授权

EP2224977B1 ANALYTE MONITORING AND FLUID DISPENSING SYSTEM 有权转让
标题翻译：分析物监测和流体分配系统
公开(公告)号：EP2224977B1
公开(公告)日：2017-07-05
申请号：EP08851596.0
申请日：2008-11-20
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： YODFAT, Ofer , KAIDAR, Ruthy
IPC分类号： A61M5/172 , A61M5/142
CPC分类号： A61M5/14248 , A61M5/1723 , A61M2005/14268 , A61M2005/1726 , A61M2205/3592 , A61M2205/50 , A61M2205/8206 , A61M2210/04 , A61M2230/201

6. 发明授权

EP2167168B1 TAILORED BASAL INSULIN DELIVERY SYSTEM 有权转让
标题翻译：胰岛素 - 输液系统麻醉药物个体化基因组蛋白
公开(公告)号：EP2167168B1
公开(公告)日：2017-05-10
申请号：EP08763620.5
申请日：2008-06-25
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： YODFAT, Ofer , SHAPIRA, Gali , GESCHEIT, Iddo, M.
IPC分类号： A61M5/172 , G06F19/00 , A61M5/142
CPC分类号： A61M5/14248 , A61M5/1723 , A61M2005/14208 , A61M2005/14268 , A61M2005/14296 , A61M2005/1726 , A61M2205/3569 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3468
摘要： Disclosed is a system to deliver insulin to a user's body. The system includes a dispensing unit to deliver the insulin to the body, and a control mechanism to control delivery of basal insulin according to a predetermined basal infusion pattern, the basal infusion pattern selected from a plurality of predetermined basal infusion patterns. In some embodiments, selection of the basal infusion pattern may be based on one or more personal characteristics of the user.
摘要翻译：公开了一种将胰岛素输送给用户身体的系统。该系统包括用于将胰岛素输送到身体的分配单元，以及控制机构，用于根据预定的基础灌注模式控制基础胰岛素的输送，所述基础灌注模式选自多个预定的基础灌注模式。在一些实施例中，基础输注模式的选择可以基于用户的一个或多个个人特征。

7. 发明授权

EP2174128B8 METHOD AND DEVICE FOR ASSESSING CARBOHYDRATE-TO-INSULIN RATIO 有权转让
标题翻译： VERFAHREN UND VORRICHTUNG ZUR TESTUNG EINES KOHLENHYDRAT-INSULIN-VERHÄLTNISSES
公开(公告)号：EP2174128B8
公开(公告)日：2017-01-11
申请号：EP08826517.8
申请日：2008-06-20
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： YODFAT, Ofer , SHAPIRA, Gali , GESCHEIT, Iddo, M.
IPC分类号： G06F19/00
CPC分类号： A61B5/14503 , A61B5/0002 , A61B5/14532 , A61B5/4839 , A61B5/6849 , A61B2562/0295 , A61K38/28 , A61M5/14248 , A61M5/1723 , A61M2005/14208 , A61M2005/14268 , A61M2005/1726 , A61M2205/3569 , A61M2205/3592 , G01N33/66 , G06F19/00 , G16H50/20
摘要： A system and a method for determining an assessed carbohydrate to insulin ratio of a patient is described. The system and the method can comprise a memory component adapted for storing an initial set of values comprising at least one of a blood glucose level, a target blood glucose level, an insulin sensitivity, and, an estimated carbohydrate to insulin ratio. The system and the method can also comprise a bolus selection component adapted for selecting a test bolus corresponding to the determined initial set of values and a planned meal. In one implementation, the bolus selection component can receive bolus dose input from a user. In another implementation, the bolus selection component can estimate the bolus dose using a set of available inputs (e.g. the amount of carbohydrates in the planned meal). The system and the method can further comprise a user interface component adapted for receiving a confirmation that the test bolus has been administered to the patient. In some implementations, the user interface component can be adapted for selecting a meal of a known content.
摘要翻译：描述了用于确定患者的评估的碳水化合物与胰岛素比例的系统和方法。系统和方法可以包括适于存储包括血糖水平，目标血糖水平，胰岛素敏感性和估计的碳水化合物与胰岛素比率中的至少一个的初始值集合的存储器组件。系统和方法还可以包括适于选择对应于所确定的初始值值和计划膳食的测试团块的推注选择组件。在一个实施方案中，推注选择组件可以从用户接收推注剂量输入。在另一个实施方案中，推注选择组分可以使用一组可用的输入（例如，计划中的膳食中碳水化合物的量）来估计推注剂量。该系统和方法还可以包括用于接收已经向患者施用测试团块的确认的用户界面组件。在一些实现中，用户界面组件可以适于选择已知内容的餐。

8. 发明授权

EP2303359B1 MODULAR MEDICAL INFUSION DEVICE WITH MEANS FOR IDENTIFICATION/AUTHENTICATION BETWEEN ITS COMPONENTS 有权转让
公开(公告)号：EP2303359B1
公开(公告)日：2020-02-26
申请号：EP09754345.8
申请日：2009-05-27
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： YODFAT, Ofer , KERET, Avihoo, P.
IPC分类号： A61M5/142 , A61M5/145 , G16H20/17 , A61M5/172 , G16H40/63 , A61B5/145

9. 发明授权

EP2635323B1 FLUID DISPENSING DEVICE WITH A FLOW DETECTOR 有权转让
公开(公告)号：EP2635323B1
公开(公告)日：2020-01-15
申请号：EP11782046.4
申请日：2011-10-29
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： YODFAT, Ofer , NETA, Avraham , TSYPKO, Nikolay , TSYPKO, Konstantin
IPC分类号： A61M5/168 , A61M5/142

10. 发明授权

EP2044544B1 FLUID DELIVERY DEVICE AND METHODS OF ITS OPERATION 有权转让
标题翻译：流体输送装置及其操作方法
公开(公告)号：EP2044544B1
公开(公告)日：2018-04-18
申请号：EP07866615.3
申请日：2007-07-06
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： YODFAT, Ofer , NIR-SHAFRIR, Ido
IPC分类号： G06F19/00
CPC分类号： G16H40/40 , A61M2005/14268 , G05D7/0676 , G06F19/3468 , G16H20/13 , G16H20/17 , G16H40/63 , G16H40/67
摘要： A method (1000) of maintaining a fluid delivery logbook on a dispensing unit of a fluid delivery device, comprising: generating (1002), at a beginning of a current communication cycle, a dispensing unit status message; adding (1006) unacknowledged logbook entries to the dispensing unit status message if a logbook comprises entries that have not been acknowledged by a command means paired to the dispensing unit; sending (1010) the dispensing unit status message to the command means; recording (1014) receipt of the logbook entries in the dispensing unit status message if an acknowledgment message is received from the command means; and waiting (1016) for a next communication cycle.

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