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1. 发明公开

EP1999122A1 STATIONARY PHASE AND COLUMN USING CUCURBITURIL BONDED SILICA GEL, AND SEPARATION METHOD OF TAXOL USING THE COLUMN 有权
标题翻译：固定相和柱，使用CUCURBITURILGEBUNDENEM硅胶和方法分离紫杉醇使用列
公开(公告)号：EP1999122A1
公开(公告)日：2008-12-10
申请号：EP06732696.7
申请日：2006-03-24
申请人： Postech Foundation , Postech Academy-Industry Foundation
发明人： KIM, Kimoon , KO, Young-Ho , PARK, Kyeng-Min , SELVAPALAM, Narayanan , NAGARAJAN, Erumaipatty, R.
IPC分类号： C07D305/14 , C07D487/04
CPC分类号： C07D487/04 , B01J20/286 , C07D305/14
摘要： Provided are a stationary phase and a column using a cucurbituril-bound silica g el, and a method of separating taxane using the column. The taxane separation meth od includes: preparing a column for taxane separation, the column being packed with a stationary phase including a cucurbituril-bound silica gel in which a cucurbituril represen ted by Formula 1 or 2 is covalently bound to a modified silica gel represented by Formul a 3; dissolving a taxane powder in a solvent to prepare a taxane-containing solution; ap plying the taxane-containing solution to the column; supplying a mobile-phase solvent t o the column to obtain a taxane extract from the column; and purifying taxane from the t axane extract. Therefore, highly purified taxane can be separated from a low-purity cr ude taxane extract.

2. 发明公开

EP1951723A1 THE APPLICATION USING NON-COVALENT BOND BETWEEN A CUCURBITURIL DERIVATIVE AND A LIGAND 有权
标题翻译：申请的甲CUCURBITURIILDERIVAT和配体之间的非共价键的
公开(公告)号：EP1951723A1
公开(公告)日：2008-08-06
申请号：EP06716137.2
申请日：2006-02-28
申请人： Postech Academy-Industry Foundation
发明人： KIM, Kimoon , BAEK, Kangkyun , KIM, Jeeyoun , HWANG, Ilha , KO, Young-Ho , SELVAPALAM, Narayanan , NAGARAJAN, Erumaipatty R. , PARK, Kyeng-Min
IPC分类号： C07D487/04
CPC分类号： C07D487/22 , B01D15/3804 , B01J31/0249 , B01J31/0251 , B01J31/1658 , B82Y5/00 , B82Y15/00 , C07K1/22
摘要： Provided are a kit including a first component that is a compound of formula (1) below bound to a first material and a second component that is a ligand bound to a second material, wherein each of the first and second materials is independently selected from the group consisting of a solid phase, a biomolecule, an antioxidant, a chemical therapeutic agent, an anti-histaminic agent, a cucurbituril dendrimer, a cyclodextrin derivative, a crown ether derivative, a calixarene derivative, a cyclophane derivative, a cyclic peptide derivative, a metallic ion, a chromophore, a fluorescent material, a phosphor, a radioactive material, and a catalyst; and the ligand can non-covalently bind to the compound of formula (1); a method of separating and purifying a material bound to a ligand using the compound of formula (1) bound to a solid phase; a method of separating and purifying the compound of formula (1) or a material bound to the compound using a ligand bound to a solid phase; a sensor chip including a compound of formula (1) bound to a first material and a ligand bound to a second material; and a solid-catalyst complex including the compound of formula (1) bound to a first material and a ligand bound to a second material.
摘要翻译：本发明提供一种试剂盒，其包括第一组分没有被式（1）下面结合的化合物的第一材料，并从所选择的第二组分也被绑定到第二材料的配体，worin每个第一和第二材料中的是unabhängig 组由固体相，生物分子的，衍生的抗氧化剂，化学治疗剂，抗组胺剂，葫芦脲树枝状聚合物，环糊精衍生物，冠醚衍生物，杯芳烃衍生物，环芳衍生物，环肽，金属离子，生色团，荧光材料，磷酸盐，放射性材料，和催化剂; 和配体可以非共价结合于式（1）化合物; 分离和纯化绑定到使用式的化合物的配体的材料的方法（1）结合于固相; 分离和纯化的式（1）的化合物或结合使用结合于固相上的配位体的化合物的材料的方法; 传感器芯片，包括下式的化合物（1）结合到第一材料和结合到第二材料的配体; 和固体催化剂络合物包括式（1）化合物结合到第一材料和结合到第二材料的配体。

3. 发明授权

EP1951723B1 THE APPLICATION USING NON-COVALENT BOND BETWEEN A CUCURBITURIL DERIVATIVE AND A LIGAND 有权
标题翻译：非共价键在酞菁衍生物和配体之间的应用
公开(公告)号：EP1951723B1
公开(公告)日：2017-08-30
申请号：EP06716137.2
申请日：2006-02-28
申请人： Postech Academy-Industry- Foundation
发明人： KIM, Kimoon , BAEK, Kangkyun , KIM, Jeeyoun , HWANG, Ilha , KO, Young-Ho , SELVAPALAM, Narayanan , NAGARAJAN, Erumaipatty R. , PARK, Kyeng-Min
IPC分类号： C07D487/04 , B01D15/38 , B01J31/02 , B01J31/16 , C07K1/22 , C07D487/22 , B01J20/00
CPC分类号： C07D487/22 , B01D15/3804 , B01J31/0249 , B01J31/0251 , B01J31/1658 , B82Y5/00 , B82Y15/00 , C07K1/22

4. 发明授权

EP1999122B1 STATIONARY PHASE AND COLUMN USING CUCURBITURIL BONDED SILICA GEL, AND SEPARATION METHOD OF TAXOL USING THE COLUMN 有权
标题翻译：酞菁键合硅胶固定相和柱状物及紫杉醇柱分离方法的研究
公开(公告)号：EP1999122B1
公开(公告)日：2010-11-24
申请号：EP06732696.7
申请日：2006-03-24
申请人： Postech Foundation , Postech Academy-Industry Foundation
发明人： KIM, Kimoon , KO, Young-Ho , PARK, Kyeng-Min , SELVAPALAM, Narayanan , NAGARAJAN, Erumaipatty, R.
IPC分类号： C07D305/14 , C07D487/04
CPC分类号： C07D487/04 , B01J20/286 , C07D305/14
摘要： Provided are a stationary phase and a column using a cucurbituril-bound silica g el, and a method of separating taxane using the column. The taxane separation meth od includes: preparing a column for taxane separation, the column being packed with a stationary phase including a cucurbituril-bound silica gel in which a cucurbituril represen ted by Formula 1 or 2 is covalently bound to a modified silica gel represented by Formul a 3; dissolving a taxane powder in a solvent to prepare a taxane-containing solution; ap plying the taxane-containing solution to the column; supplying a mobile-phase solvent t o the column to obtain a taxane extract from the column; and purifying taxane from the t axane extract. Therefore, highly purified taxane can be separated from a low-purity cr ude taxane extract.
摘要翻译：提供了使用葫芦脲结合硅胶的固定相和柱以及使用该柱分离紫杉烷的方法。紫杉烷分离方法包括：制备紫杉烷分离柱，所述柱填充有包含葫芦脲结合硅胶的固定相，其中由式1或2代表的葫芦脲与由以下代表的改性硅胶共价结合： Formul a 3; 将紫杉烷粉末溶解在溶剂中以制备含紫杉烷的溶液; 将含有紫杉烷的溶液加入柱中; 向柱提供流动相溶剂以从柱中获得紫杉烷提取物; 并从泰山提取物中纯化紫杉烷。因此，高纯度紫杉烷可以从低纯度紫杉烷萃取物中分离出来。

5. 发明公开

EP1942752A1 CUCURBITURIL ADDED CIGARETTES AND MANUFACTURING METHOD THEREOF 审中-公开
标题翻译：与为了增加葫和方法及其香烟
公开(公告)号：EP1942752A1
公开(公告)日：2008-07-16
申请号：EP06716291.7
申请日：2006-03-09
申请人： Postech Academy-Industry Foundation
发明人： KIM, Kimoon , PARK, Kyeng-Min , KO, Young-Ho , SELVAPALAM, Narayanan
IPC分类号： A24D3/04
CPC分类号： A24D1/002 , A24D3/14
摘要： Provided is a cucurbituril-containing tobacco. The cucurbituril-containing tobacco includes a cucurbituril represented by Formula 1. The cucurbituril-containing tobacco can produce a reduced amount of harmful substances.

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