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1. 发明公开

EP3603486A3 SURGICAL MICROSCOPE WITH INTEGRATED OPTICAL COHERENCE TOMOGRAPHY AND DISPLAY SYSTEMS 审中-实审转让
公开(公告)号：EP3603486A3
公开(公告)日：2020-04-15
申请号：EP19191929.9
申请日：2016-06-07
申请人： Novartis AG
发明人： YU, Lingfeng , SHOFMAN, Vadim , HEEREN, Tammo , REN, Hugang
IPC分类号： A61B3/10 , A61B3/13
摘要： An ophthalmic surgical microscope includes an OCT system comprises an OCT light source for generating an OCT imaging beam, a beam coupler for directing the OCT imaging beam along an optical path to a patient's eye, wherein at least a portion of the OCT imaging beam reflected by the patient's eye is returned to the OCT system, and wherein the OCT system is operable to generate an OCT image based on the reflected portion of the OCT imaging beam; an imaging unit for generating a fundus image of the patient's eye; a tracking system that processes the fundus image to calculate a location of a surgical instrument inserted into the patient's eye. The OCT system further comprises a beam scanner for directing the OCT imaging beam to a particular region on a plane substantially orthogonal with the optical path within the patient's eye, the particular region including the calculated location of the surgical instrument inserted into the patient's eye. The OCT system comprises a real-time data projection unit for projecting the OCT image generated by the OCT system and a first beamsplitter for directing the OCT image projected by the real-time data projection to a first eyepiece of the ophthalmic surgical microscope such that the OCT image projected by the real-time data projection unit is viewable through the first eyepiece.

2. 发明公开

EP3603486A2 SURGICAL MICROSCOPE WITH INTEGRATED OPTICAL COHERENCE TOMOGRAPHY AND DISPLAY SYSTEMS 审中-实审转让
公开(公告)号：EP3603486A2
公开(公告)日：2020-02-05
申请号：EP19191929.9
申请日：2016-06-07
申请人： Novartis AG
发明人： YU, Lingfeng , SHOFMAN, Vadim , HEEREN, Tammo , REN, Hugang
IPC分类号： A61B3/10 , A61B3/13
摘要： An ophthalmic surgical microscope includes an OCT system comprises an OCT light source for generating an OCT imaging beam, a beam coupler for directing the OCT imaging beam along an optical path to a patient's eye, wherein at least a portion of the OCT imaging beam reflected by the patient's eye is returned to the OCT system, and wherein the OCT system is operable to generate an OCT image based on the reflected portion of the OCT imaging beam; an imaging unit for generating a fundus image of the patient's eye; a tracking system that processes the fundus image to calculate a location of a surgical instrument inserted into the patient's eye. The OCT system further comprises a beam scanner for directing the OCT imaging beam to a particular region on a plane substantially orthogonal with the optical path within the patient's eye, the particular region including the calculated location of the surgical instrument inserted into the patient's eye. The OCT system comprises a real-time data projection unit for projecting the OCT image generated by the OCT system and a first beamsplitter for directing the OCT image projected by the real-time data projection to a first eyepiece of the ophthalmic surgical microscope such that the OCT image projected by the real-time data projection unit is viewable through the first eyepiece.

3. 发明授权

EP3265995B1 OCT IMAGE MODIFICATION 有权转让
公开(公告)号：EP3265995B1
公开(公告)日：2019-03-20
申请号：EP16726656.8
申请日：2016-05-16
申请人： Novartis AG
发明人： YU, Lingfeng , REN, Hugang , PAPAC, Michael J.
IPC分类号： G06T5/00 , G06T7/70

4. 发明授权

EP3082569B1 MARKER-BASED TOOL TRACKING 有权转让
公开(公告)号：EP3082569B1
公开(公告)日：2019-02-27
申请号：EP14872305.9
申请日：2014-12-05
申请人： Novartis AG
发明人： REN, Hugang , YU, Lingfeng
IPC分类号： A61B3/12 , A61B3/14 , A61B18/22 , A61F9/007 , A61B3/00 , A61B3/10

5. 发明公开

EP3265008A1 SURGICAL TOOL TRACKING TO CONTROL SURGICAL SYSTEM 有权转让
标题翻译：手术工具跟踪控制手术系统
公开(公告)号：EP3265008A1
公开(公告)日：2018-01-10
申请号：EP16709863.1
申请日：2016-02-23
申请人： Novartis AG
发明人： REN, Hugang , YU, Lingfeng
IPC分类号： A61B34/00 , A61F9/007 , G06F3/01 , A61B34/20 , A61B17/00 , A61B90/00
CPC分类号： A61F9/007 , A61B3/13 , A61B34/20 , A61B34/25 , A61B90/20 , A61B2017/00207 , A61B2034/2048 , A61B2034/2055 , A61B2034/2065 , A61B2034/254 , A61B2090/371 , A61B2090/372 , A61F9/00736 , G06F1/163 , G06F3/011 , G06F3/017 , G06F3/0482
摘要： A surgical system uses a surgical tool as a control input. A tracking unit tracks a motion of the surgical tool, and a processing unit for processes the motion of the surgical tool to obtain a temporal spatial information of the surgical tool. The control unit further comprises a control input unit with a number of control commands. The control input unit associates the temporal spatial information of the surgical tool with a corresponding control command.

6. 发明公开

EP3313338A1 CONTROL OF SCANNING IMAGES DURING VITREORETINAL SURGERY 有权转让
标题翻译：对视网膜手术期间扫描图像的控制
公开(公告)号：EP3313338A1
公开(公告)日：2018-05-02
申请号：EP16739577.1
申请日：2016-06-30
申请人： Novartis AG
发明人： HOPKINS, Mark , SANCHEZ, Robert , TAKAKAWA, Ryan , YU, Lingfeng , REN, Hugang
IPC分类号： A61F9/008 , A61F9/007
CPC分类号： A61B3/0025 , A61B3/0033 , A61B3/0058 , A61B3/102 , A61B3/13 , A61B90/20 , A61F9/00821 , A61F2009/00863
摘要： Control of scanning images during ophthalmic surgery may be performed with a scanning controller that interfaces to an optical scanner used with a surgical microscope. A scan control device may receive user input, including hands-free user input, for controlling an overlay image of scanning data that is overlaid on optical image data viewed using the surgical microscope. A selected location for optical scanning may also be displayed and controlled using the scanning controller.

7. 发明公开

EP3282925A1 SURGICAL MICROSCOPE WITH INTEGRATED OPTICAL COHERENCE TOMOGRAPHY AND DISPLAY SYSTEMS 有权转让
标题翻译：集成光学相干层析和显示系统的外科显微镜
公开(公告)号：EP3282925A1
公开(公告)日：2018-02-21
申请号：EP16729379.4
申请日：2016-06-07
申请人： Novartis AG
发明人： YU, Lingfeng , SHOFMAN, Vadim , HEEREN, Tammo , REN, Hugang
IPC分类号： A61B3/10 , A61B3/13
CPC分类号： A61B3/132 , A61B3/0025 , A61B3/10 , A61B3/102 , A61B3/12
摘要： An ophthalmic surgical microscope includes a beam coupler positioned along an optical path of the surgical microscope between a first eyepiece and magnifying/focusing optics, the beam coupler operable to direct the OCT imaging beam along a first portion of the optical path of the surgical microscope between the beam coupler and a patient's eye (an OCT image being generated based on a reflected portion of the OCT imaging beam). The surgical microscope additionally includes a real-time data projection unit operable to project the OCT image generated by the OCT system and a beam splitter positioned along the optical path of the surgical microscope between a second eyepiece and the magnifying/focusing optics. The beam splitter is operable to direct the projected OCT image along a second portion of the optical path of the surgical microscope between the beam splitter and the second eyepiece such that the projected OCT image is viewable through the second eyepiece.

8. 发明公开

EP3512407A1 SUBTRACTIVE EN FACE OPTICAL COHERENCE TOMOGRAPHY IMAGING 审中-实审转让
公开(公告)号：EP3512407A1
公开(公告)日：2019-07-24
申请号：EP17777962.6
申请日：2017-09-05
申请人： Novartis AG
发明人： CHARLES, Steven , YU, Lingfeng , REN, Hugang
IPC分类号： A61B3/10 , A61B3/13

9. 发明授权

EP3230949B1 SYSTEMS AND METHODS FOR DUAL VITREOUS AND RETINA IMAGING 有权转让
公开(公告)号：EP3230949B1
公开(公告)日：2019-05-01
申请号：EP16708258.5
申请日：2016-02-10
申请人： Novartis AG
发明人： YU, Lingfeng , REN, Hugang
IPC分类号： G06T5/50

10. 发明公开

EP3360112A1 FAST AND AUTOMATED SEGMENTATION OF LAYERED IMAGE WITH HEURISTIC GRAPH SEARCH 有权转让
公开(公告)号：EP3360112A1
公开(公告)日：2018-08-15
申请号：EP16819664.0
申请日：2016-12-02
申请人： Novartis AG
发明人： REN, Hugang , YU, Lingfeng
IPC分类号： G06T7/13 , G06T7/162 , G06T7/181
CPC分类号： G06T7/181 , G06T7/13 , G06T7/162 , G06T7/90 , G06T2207/10101 , G06T2207/10132 , G06T2207/20016 , G06T2207/30041
摘要： A method of processing an ophthalmic image includes: taking an image of an ophthalmic region involving an ophthalmic layer by an imaging system; constructing an image graph, comprising nodes connected by links and detected image data by an image processor; and performing a heuristic graph-search for a path on the image graph that corresponds to an image of the ophthalmic layer by assigning at least one of link-costs to links of the image graph and node-costs to nodes of the image graph; assigning heuristic-costs to at least one of the nodes and the links; creating extended paths by extending a selected path with extension links; determining path-costs of the extended paths by combining heuristic costs and at least one of link-costs and node-costs assigned to the extension-links; and selecting the extended path with the smallest path-cost.

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