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1. 发明公开

EP1382363A1 Closed loop system for controlling blood glucose levels 审中-公开
标题翻译： Geschlossene Regelkreisvorrichtung zur Regelung des Blutglukosespiegels
公开(公告)号：EP1382363A1
公开(公告)日：2004-01-21
申请号：EP02388046.1
申请日：2002-07-15
申请人： NOVO NORDISK A/S
发明人： Storgaard-Larsen, Torben , Bielecki, Mia , Panduro, Rasmus , Steenholt, Lars , Skyggebjerg, Ole , Ulrich, Finn , Shalmi, Michael , Dall, Mads Henrik
IPC分类号： A61M5/172
CPC分类号： A61M5/1723 , A61M2005/1726 , A61M2230/201
摘要： The present invention relates to closed loop drug delivery systems. More specifically, the invention relates to systems for controlling the infusion rate of a drug or other substance having a regulating effect, especially of blood glucose. Thus, in a first aspect the present invention provides closed loop system comprising a sensor assembly having a sensor system adapted for providing a sensor signal indicative of a glucose level in blood, flow means for establishing a flow of blood from a patient to the sensor assembly and for returning at least a portion of the blood back to the patient, control means adapted to receive the signals from the sensor system and generate command signals in response thereto in order to keep the blood glucose level of the patient within a desired range, as well as delivery means for delivering an amount of at least one drug having a blood glucose regulating effect, wherein operation of the delivery means is affected by the command signals.
摘要翻译：本发明涉及闭环药物递送系统。更具体地，本发明涉及用于控制具有调节作用，特别是血糖的药物或其他物质的输注速率的系统。因此，在第一方面，本发明提供闭环系统，其包括传感器组件，该传感器组件具有适于提供指示血液中的葡萄糖水平的传感器信号的传感器系统，用于建立从患者到所述传感器组件的血液流动的流动装置并且用于将至少一部分血液返回给患者，控制装置适于从传感器系统接收信号并响应于此产生命令信号，以将患者的血糖水平保持在期望的范围内，如以及用于递送至少一种具有血糖调节作用的药物的递送装置，其中输送装置的操作受命令信号的影响。

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