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1. 发明公开

EP1228044A2 PYRROLOIMIDAZOL-DERIVATE UND IHRE VERWENDUNG ALS ARZNEIMITTEL 审中-公开
标题翻译： Pyrroloimidazole衍生物及其药物AS
公开(公告)号：EP1228044A2
公开(公告)日：2002-08-07
申请号：EP00981195.1
申请日：2000-10-09
申请人： Morphochem AG
发明人： DOEMLING, Alexander , BECK, Barbara
IPC分类号： C07D233/00
CPC分类号： C07D401/14 , C07D403/04 , C07D471/04
摘要： The invention relates to 3-pyrrolo imidazole derivatives of general formula (I), wherein: the imidazole radical is an optionally substituted imidazole cycle; X, Y, A and B, independent of one another, represent carbon atoms or nitrogen atoms; radicals Z, independent of one another, represent a hydrogen atom, a halogen atom, a pseudohalogen, an optionally substituted alkyl radical, alkenyl radical, alkynyl radical, aralkyl radical, aralkenyl radical, aralkynyl radical, cycloalkyl radical, cycloalkenyl radical, cycloalkynyl radical, cycloaralkyl radical, cycloaralkenyl radical, cycloaralkynyl radical, aryl radical, alkoxy radical or an optionally substituted ring, on which one or two additional optionally substituted rings can be anellated, and/or at least two of the radicals Z can be part of an optionally substituted ring, on which one or two additional optionally substituted rings can be anellated. The invention also relates to pharmaceutical compositions which contain at least one of the aforementioned compounds, optionally in conjunction with conventional supports and/or adjuvants and/or auxiliary agents, and to their use, in particular, as medicaments which resolve tumors and cancer, and which, quite particularly, are used as antibiotic, in particular, antibacterial medicaments.

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