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1. 发明授权

EP2821145B1 Centrifugation chamber with gas-permeable membranes layers for cell cultivation 有权转让
公开(公告)号：EP2821145B1
公开(公告)日：2019-08-21
申请号：EP13174604.2
申请日：2013-07-02
申请人： Miltenyi Biotec GmbH
发明人： Kabaha, Eiad Dr. , Peters, Ralf-Peter Dr. , Miltenyi, Stefan
IPC分类号： B04B1/00 , B04B5/04 , B04B5/10 , B04B7/12 , B04B11/06 , C12M1/00 , C12M1/04 , C12M1/12 , C12M3/04

2. 发明公开

EP2540394A1 Device for fragmenting tissue 有权转让
标题翻译： Vorrichtung zum fragmentieren von Gewebe
公开(公告)号：EP2540394A1
公开(公告)日：2013-01-02
申请号：EP11171503.3
申请日：2011-06-27
申请人： Miltenyi Biotec GmbH
发明人： Peters, Ralf-Peter Dr. , Kabaha, Eiad Dr. , Stöters, Wolfgang , Winkelmayer, Gerhard , Bucher, Franz G.
IPC分类号： B01L3/00 , B01F7/16 , B01F13/10 , B01F15/02 , B02C19/22 , G01N1/28
CPC分类号： B01L3/502 , B01F7/1695 , B01F13/1044 , B01F15/00844 , B01F2215/0431 , B01F2215/0477 , B01F2215/0481 , B01L3/50825 , B01L2200/026 , B01L2300/046 , B01L2300/0681 , B02C19/0056 , B02C19/22 , G01N1/286 , G01N2001/2873
摘要： The invention is directed to a device for fragmenting or homogenizing biological samples, comprising:
- a tubular laboratory test vessel (1) having an open first end (3) and a second end closed by a bottom (10);
- a closing lid (2) for the laboratory test vessel (1) connected to the open end (3) of the laboratory test vessel (1);
- a processing tool (5) arranged in said closing lid (2), comprising a plurality of teeth (4a-c) and an agitating element (11) having a guidance tube (13) that is rotatably mounted through a central bore in the lid (2) and includes an engagement portion (16) that is adapted to be engaged by a drive motor; wherein at least one outer cutting blade (6) is located at the periphery of the processing tool (5) and a transportation element (8) is arranged at the guidance tube (13) that extends outwardly in a helical shape over the outer cutting blade (6) and which is provided with slots (6a) fitting the outer cutting blades (6).
Furthermore, the invention is directed to a process for extracting, fragmenting, mixing or homogenizing biological samples in a device according to any of the claims 1 to 12 wherein the agitating element (11) is rotated relative to the closing lid (2) and the processing tool (5), thereby guiding the transportation element (8) over at least one group of teeth (4 a-c) and at least one outer cutting blade (6) through slots (6a) of the transportation element (8) in a grinding and cutting manner.
摘要翻译：本发明涉及用于使生物样品分裂或均化的装置，包括： - 管状实验室测试容器（1），其具有敞开的第一端（3）和由底部（10）封闭的第二端; - 连接到实验室测试容器（1）的开口端（3）的用于实验室测试容器（1）的关闭盖（2）; - 布置在所述关闭盖（2）中的处理工具（5），包括多个齿（4a-c）和搅拌元件（11），所述搅拌元件具有引导管（13），所述引导管通过所述导向管盖（2），并包括适于与驱动马达接合的接合部分（16）; 其中至少一个外切割刀片（6）位于所述加工工具（5）的周边处，并且在所述引导管（13）处布置有输送元件（8），所述引导管（13）以螺旋形状向外延伸到所述外切割刀片（6），并且设置有装配外切割刀片（6）的槽（6a）。此外，本发明涉及一种用于在根据权利要求1至12中任一项所述的装置中提取，分段，混合或均化生物样品的方法，其中所述搅拌元件（11）相对于所述关闭盖（2）旋转，并且处理工具（5），从而通过运送元件（8）的槽（6a）在磨削中将运输元件（8）引导至少一组齿（4交流）和至少一个外切割刀片（6）切割方式。

3. 发明授权

EP2540394B1 Device for fragmenting tissue 有权转让
标题翻译：一种用于破碎组织的装置
公开(公告)号：EP2540394B1
公开(公告)日：2016-05-04
申请号：EP11171503.3
申请日：2011-06-27
申请人： Miltenyi Biotec GmbH
发明人： Peters, Ralf-Peter Dr. , Kabaha, Eiad Dr. , Stöters, Wolfgang , Winkelmayer, Gerhard , Bucher, Franz G.
IPC分类号： B01F15/00 , B02C19/00 , B01F13/10 , B01F7/16 , B01L3/00 , B02C19/22 , G01N1/28
CPC分类号： B01L3/502 , B01F7/1695 , B01F13/1044 , B01F15/00844 , B01F2215/0431 , B01F2215/0477 , B01F2215/0481 , B01L3/50825 , B01L2200/026 , B01L2300/046 , B01L2300/0681 , B02C19/0056 , B02C19/22 , G01N1/286 , G01N2001/2873

4. 发明公开

EP2664367A1 Stackable cell strainer 审中-公开
标题翻译：可堆叠细胞过滤器
公开(公告)号：EP2664367A1
公开(公告)日：2013-11-20
申请号：EP12167980.7
申请日：2012-05-15
申请人： Miltenyi Biotec GmbH
发明人： Poggel, Carsten Dr. , Kabaha, Eiad Dr. , Adams, Timo , Stöters, Wolfgang , Bosio, Andreas
IPC分类号： B01D29/085
CPC分类号： B01D35/306 , B01L3/5021 , B01L2200/023 , B01L2200/0684 , B01L2300/0681 , B01L2300/087 , C12M47/02
摘要： The invention is directed to a cell strainer for separating particles from a cell suspension, comprising an upper portion with at least one filter area essential perpendicular to the direction of flow of the suspension and a lower portion adapted to fit into the openings of at least two tubes with different sized openings wherein the lower portion has a first section comprising shoulders or flanges having the diameter of the opening of a first tube and at least one second section comprising a recess for receiving the neck of a second tube, wherein the diameter of the first section is larger as the diameter of the second section.
摘要翻译：本发明涉及一种用于从细胞悬浮液中分离颗粒的细胞过滤器，该细胞过滤器包括具有基本上垂直于悬浮液流动方向的至少一个过滤器区域的上部和适于配合到至少两个开口中的下部具有不同尺寸的开口的管，其中所述下部具有第一部分和第二部分，所述第一部分包括具有第一管的开口的直径的肩部或凸缘，所述第二部分包括用于接收第二管的颈部的凹部，第一部分大于第二部分的直径。

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