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    • 6. 发明公开
    • THERAPY DELIVERY METHOD AND SYSTEM FOR IMPLANTABLE MEDICAL DEVICES
    • 治疗VERFAHREN UND SYSTEMFÜRIMPLANTIERBARE MEDISINISCHE VORRICHTUNGEN
    • EP2900320A1
    • 2015-08-05
    • EP13784044.3
    • 2013-09-25
    • Medtronic Inc.
    • CABELKA, Lonny V.CRUTCHFIELD, Randolph E.BOONE, Mark R.RASMUSSEN, Marshall J.
    • A61N1/378A61N1/39
    • A61N1/378A61N1/3782A61N1/3975A61N1/3981
    • Recent advancements in electronics technology have provided opportunities for enhancements to implantable medical devices. The enhancements have contributed to increasing miniaturization and operation efficiency. The techniques of the disclosure facilitate configuring a stimulation therapy waveform based on a patient's physiological response to the stimulation waveform. The generated therapy stimulation waveforms include a stepped leading-edge that may be shaped having a varying slope and varying amplitudes associated with each of the segments of the slope. Unlike the truncated exponential waveform delivered by the conventional therapy delivery circuit which is based on the behavior of the output capacitors (i.e., i=C(dV/dt)), the stimulation waveform of the present disclosure may be dynamically shaped as a function of an individual patient's response. The dynamically shaped therapy stimulation waveforms facilitate achieving lower capture thresholds which reduces the device's supply consumption and reduction of tissue damage.
    • 电子技术的最新进展为植入式医疗设备的增强提供了机会。 增强功能有助于提高小型化和运营效率。 本公开的技术有助于基于患者对刺激波形的生理反应来配置刺激治疗波形。 产生的治疗刺激波形包括阶梯式前缘,其可以被成形为具有与斜率的每个段相关联的变化的斜率和变化的幅度。 与基于输出电容器的行为(即,i = C(dV / dt))的传统治疗传递电路传递的截断指数波形不同,本公开的刺激波形可以动态地形成为 个人病人的反应。 动态形状的治疗刺激波形有助于实现较低的捕获阈值,这降低了装置的供应消耗并减少了组织损伤。