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1. 发明授权

EP1418982B1 APPARATUS TO CONTROL DELIVERY OF HIGH-VOLTAGE AND ANTI-TACHY PACING THERAPY IN AN IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：一种用于控制高电压和antitachycardic起搏治疗应用程序在可植入医疗装置
公开(公告)号：EP1418982B1
公开(公告)日：2012-12-19
申请号：EP02763358.5
申请日：2002-07-25
申请人： Medtronic, Inc.
发明人： DEGROOT, Paul, J. , OUSDIGIAN, Kevin, T. , PADMANABHAN, Vasant , KRAUSE, Paul, G. , SHARMA, Vinod
IPC分类号： A61N1/362
CPC分类号： A61N1/3622 , A61N1/3688 , A61N1/3925 , A61N1/3956 , A61N1/3962 , A61N1/3987

2. 发明授权

EP1515778B1 APPARATUS FOR PREVENTION OF ARRHYTHMIA CLUSTERS USING OVERDRIVE PACING 有权
标题翻译：装置，以防止心律失常集群使用超速脉冲
公开(公告)号：EP1515778B1
公开(公告)日：2008-02-20
申请号：EP03760405.5
申请日：2003-06-13
申请人： MEDTRONIC, INC.
发明人： PADMANABHAN, Vasant , OLSON, Walter, H. , MEHRA, Rahul , ZHOU, Xiaohong , MULLEN, Thomas, J. , GEORGE, William, J.
IPC分类号： A61N1/37
CPC分类号： A61N1/3622
摘要： An implantable medical device that includes a microprocessor that characterizes cardiac activity of apatient to enable the implantable medical device to deliver therapy in response to an identified arrhythmia event. A monitor/controller monitors the characterized cardiac activity and the delivered therapy, and controls activation of triggered overdrive pacing subsequent to the delivered therapy.

3. 发明授权

EP1501600B1 COMBINED ANTI-TACHYCARDIA PACING (ATP) AND HIGH VOLTAGE THERAPY FOR TREATING VENTRICULAR ARRHYTHMIAS 有权
标题翻译：联合抗心动过速 - PACE和高压治疗室性心律失常的治疗
公开(公告)号：EP1501600B1
公开(公告)日：2009-05-13
申请号：EP03747564.7
申请日：2003-03-10
申请人： MEDTRONIC, INC.
发明人： OUSDIGIAN, Kevin, T. , PADMANABHAN, Vasant , DEGROOT, Paul, J. , SHARMA, Vinod , KASZAS, Cameron, J. , KRAUSE, Paul, G. , OLSON, Walter, H.
IPC分类号： A61N1/39
CPC分类号： A61N1/3962 , A61N1/3987
摘要： The present invention provides a system and method for treating an arrhythmia of the heart. The system and method involves delivery of anti-tachy pacing (ATP) pulses to the heart, possibly followed by the delivery of a high-voltage shock. ATP delivery is controlled such that the time of delivery of any high-voltage shock is not affected by the prior delivery of the ATP pulses. System control may be accomplished using one or more programmable parameters, which may include a user-specified shock energy.

4. 发明公开

EP1418982A2 METHOD AND APPARATUS TO CONTROL DELIVERY OF HIGH-VOLTAGE AND ANTI-TACHY PACING THERAPY IN AN IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：一种用于控制高电压和antitachycardic起搏治疗应用程序在可植入医疗装置
公开(公告)号：EP1418982A2
公开(公告)日：2004-05-19
申请号：EP02763358.5
申请日：2002-07-25
申请人： Medtronic, Inc.
发明人： DEGROOT, Paul, J. , OUSDIGIAN, Kevin, T. , PADMANABHAN, Vasant , KRAUSE, Paul, G. , SHARMA, Vinod
IPC分类号： A61N1/362
CPC分类号： A61N1/3622 , A61N1/3688 , A61N1/3925 , A61N1/3956 , A61N1/3962 , A61N1/3987
摘要： A system and method for delivering both anti-tachy pacing (ATP) therapy and high-voltage shock therapy in response to detection of abnormal cardiac rhythms is disclosed. The system controls the time between delivering ATP therapy and the charging of high-voltage capacitors in preparation for shock delivery based on a predetermined set of criteria. In one embodiment, the inventive system operates in an ATP during Capacitor Charging (ATP-DCC) mode wherein all, or substantially all, of the ATP therapy is delivered during charging of the high-voltage capacitors. Based on evaluation of the predetermined set of criteria, the system may switch to an additional ATP before Capacitor Charging (ATP-BCC) mode, wherein substantially all of the ATP therapy is delivered prior to charging of the high-voltage capacitor. According to one aspect of the invention, the predetermined set of criteria is based, at least in part, on the effectiveness of previously-delivered ATP therapy.

5. 发明公开

EP1501600A2 COMBINED ANTI-TACHYCARDIA PACING (ATP) AND HIGH VOLTAGE THERAPY FOR TREATING VENTRICULAR ARRHYTHMIAS 有权
标题翻译：联合抗心动过速 - PACE和高压治疗室性心律失常的治疗
公开(公告)号：EP1501600A2
公开(公告)日：2005-02-02
申请号：EP03747564.7
申请日：2003-03-10
申请人： Medtronic, Inc.
发明人： OUSDIGIAN, Kevin, T. , PADMANABHAN, Vasant , DEGROOT, Paul, J. , SHARMA, Vinod , KASZAS, Cameron, J. , KRAUSE, Paul, G. , OLSON, Walter, H.
IPC分类号： A61N1/39
CPC分类号： A61N1/3962 , A61N1/3987
摘要： The present invention provides a system and method for treating an arrhythmia of the heart. The system and method involves delivery of anti-tachy pacing (ATP) pulses to the heart, possibly followed by the delivery of a high-voltage shock. ATP delivery is controlled such that the time of delivery of any high-voltage shock is not affected by the prior delivery of the ATP pulses. System control may be accomplished using one or more programmable parameters, which may include a user-specified shock energy.

6. 发明授权

EP1159032B1 APPARATUS FOR MONITORING HEART RATE 有权
标题翻译：用于监控心率
公开(公告)号：EP1159032B1
公开(公告)日：2004-08-11
申请号：EP00915931.0
申请日：2000-03-01
申请人： Medtronic, Inc.
发明人： PADMANABHAN, Vasant , OLSON, Walter, H.
IPC分类号： A61N1/37 , A61N1/39
CPC分类号： A61N1/3702 , A61N1/3925
摘要： An implantable monitoring device for monitoring a patient's heart rate variability over time. The device includes a cardiac electrogram amplifier, a sensing electrode coupled to an input of the amplifier, timing circuitry, processing circuitry and a memory. The timing circuitry defines successive monitoring periods each extending over a period of hours, the monitoring periods together extending at least over a period of weeks and also defines successive shorter time periods during each monitoring period. The memory stores heart intervals between depolarizations of the patient's heart sensed by the amplifier during the shorter time periods. The processing circuitry calculates median intervals between depolarizations of the patient's heart sensed by the amplifier during the shorter time periods and calculates standard deviations of the median intervals calculated during each monitoring period. The processing circuitry may also reject heart intervals occurring during tachyarrhythmias and calculate median intervals based only on heart intervals not rejected.

7. 发明公开

EP1159032A1 METHOD AND APPARATUS FOR MONITORING HEART RATE 有权
标题翻译：用于监控心率
公开(公告)号：EP1159032A1
公开(公告)日：2001-12-05
申请号：EP00915931.0
申请日：2000-03-01
申请人： Medtronic, Inc.
发明人： PADMANABHAN, Vasant , OLSON, Walter, H.
IPC分类号： A61N1/37 , A61N1/39
CPC分类号： A61N1/3702 , A61N1/3925
摘要： An implantable monitoring device for monitoring a patient's heart rate variability over time. The device includes a cardiac electrogram amplifier, a sensing electrode coupled to an input of the amplifier, timing circuitry, processing circuitry and a memory. The timing circuitry defines successive monitoring periods each extending over a period of hours, the monitoring periods together extending at least over a period of weeks and also defines successive shorter time periods during each monitoring period. The memory stores heart intervals between depolarizations of the patient's heart sensed by the amplifier during the shorter time periods. The processing circuitry calculates median intervals between depolarizations of the patient's heart sensed by the amplifier during the shorter time periods and calculates standard deviations of the median intervals calculated during each monitoring period. The processing circuitry may also reject heart intervals occurring during tachyarrhythmias and calculate median intervals based only on heart intervals not rejected.

8. 发明公开

EP1644079A1 AUTOMATIC EGM AMPLITUDE MEASUREMENTS DURING TACHYARRHYTHMIA EPISODES 审中-公开
标题翻译： AUTOMATED EGM幅度测量过程中的快速性心律失常
公开(公告)号：EP1644079A1
公开(公告)日：2006-04-12
申请号：EP04755575.0
申请日：2004-06-18
申请人： MEDTRONIC, INC.
发明人： BRANDSTETTER, John, S. , PADMANABHAN, Vasant
IPC分类号： A61N1/362 , A61N1/37 , A61B5/0456
CPC分类号： A61N1/3704 , A61B5/0456 , A61B5/0464 , A61N1/3621
摘要： In an IMD (10), when tachyarrhythmia detection criterion are satisfied or a high intrinsic heart rate is detected, a peak amplitude detection circuit (186) is enabled to detect the peak amplitude of the cardiac signal of interest, i.e., the P-wave in the case of atrial tachyarrhythmias and the R-wave in case of ventricular tachyarrhythmias. Peak amplitude data is accumulated for subsequent use in setting sensing thresholds and/or gain of a sense amplifier (128) to reduce undersensing of lower amplitude cardiac signals during such tachyarrhythmias.

9. 发明公开

EP1515778A1 METHOD AND APPARATUS FOR PREVENTION OF ARRHYTHMIA CLUSTERS USING OVERDRIVE PACING 有权
标题翻译：装置，以防止心律失常集群使用超速脉冲
公开(公告)号：EP1515778A1
公开(公告)日：2005-03-23
申请号：EP03760405.5
申请日：2003-06-13
申请人： Medtronic, Inc.
发明人： PADMANABHAN, Vasant , CAMP, Walter, H. , MEHRA, Rahul , ZHOU, Xiaohong , MULLEN, Thomas, J. , GEORGE, William, J.
IPC分类号： A61N1/37
CPC分类号： A61N1/3622
摘要： An implantable medical device that includes a microprocessor that characterizes cardiac activity of apatient to enable the implantable medical device to deliver therapy in response to an identified arrhythmia event. A monitor/controller monitors the characterized cardiac activity and the delivered therapy, and controls activation of triggered overdrive pacing subsequent to the delivered therapy.

10. 发明公开

EP1267996A2 METHOD AND APPARATUS FOR MONITORING PHYSIOLOGIC PARAMETERS IN CONJUNCTION WITH A TREATMENT REGIMEN 审中-公开
标题翻译：方法与装置相关的治疗方案监测生理参数
公开(公告)号：EP1267996A2
公开(公告)日：2003-01-02
申请号：EP01913294.3
申请日：2001-03-02
申请人： Medtronic, Inc.
发明人： OUSDIGIAN, Kevin, T. , STONE, Karen, A. , PADMANABHAN, Vasant
IPC分类号： A61N1/372
CPC分类号： A61N1/37247
摘要： A system including an implantable medical device and an associated external device, in which the implantable device is adapted to monitor a physiologic parameter and includes a telemetry system for transmitting information to and receiving information from the external device, including information regarding the measured physiological parameter and in which wherein the external device includes a telemetry system for receiving information from the implanted device and for transmitting information to the implanted device and is provided with a mechanism for receiving information indicative of occurences of significant therapeutic events and is further provided with a display system which combines information received from the implantable device related to the monitored physiologic parameter with the information of therapeutic significance and for displays the combined information in a time-scaled display in which the measured physiologic parameter is displayed along a common time scale with indications of occurences of the significant therapy related events. The implantable device may also include a mechanism for delivering a therapy; and the mechanism in the external device for receiving information indicative of occurrences of significant therapeutic events may receive information regarding changes in the therapy delivered by the implantable device. The mechanism in the external device for receiving information indicative of occurrences of significant therapeutic events may also or in addition receive information indicative of changes in the therapy delivered by a physician, e.g. changes in a drug therapy.

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