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1. 发明授权

EP0230472B1 BIOSENSOR AND METHOD OF MANUFACTURING SAME 失效
标题翻译：生物传感器及其制造方法
公开(公告)号：EP0230472B1
公开(公告)日：1993-01-27
申请号：EP86903608.7
申请日：1986-06-19
申请人： MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.
发明人： NANKAI, Shiro , KAWAGURI, Mariko , IIJIMA, Takashi
IPC分类号： G01N27/30 , G01N27/416
CPC分类号： C12Q1/004 , Y10S435/817
摘要： The electrode systems (13, 14, 15) consisting mainly of carbon on an insulated substrate (12), and the surfaces of said electrode systems are coated with an insulating layer (16) while parts (13', 14', 15') thereof being exposed. A porous member (18), which retains oxygen and electron receptors thereon, and a retainer frame (17) are then provided on the upper surface of the resultant product. A cover (19) having an opening with the diameter smaller than that of the porous member (18) is then placed on the resultant product, and all of these parts are combined integrally. Owing to such a construction, an inexpensive disposable biosensor capable of carrying out a measuring operation easily can be obtained. When heat-treated at 60-170oC for 1-8 hours during the formation of the electrode systems, the preservation stability of the biosensor can be improved. By subjecting the surfaces of the measuring electrodes to a protein adsorption treatment, the dispersion of response currents can be prevented.

2. 发明公开

EP0136362A1 BIOSENSOR 失效
标题翻译：生物传感器。
公开(公告)号：EP0136362A1
公开(公告)日：1985-04-10
申请号：EP84901016.0
申请日：1984-03-06
申请人： MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.
发明人： KAWAGURI, Mariko , NANKAI, Shiro , IIJIMA, Takashi
IPC分类号： G01N27/327
CPC分类号： C12Q1/005 , C12Q1/004
摘要： A measuring electrode (27) and an adjacent electrode (28) are embedded in an insulating substrate (26). The exposed surface of the electrode system is coated with a porous substance (29) carrying an oxidation reductase (30) and, if needed, an electron acceptor (31) in a dry state, to form a biosensor. A predetermined voltage is applied between the electrodes (27, 28) of the biosensor, and a matrix-containing sample is dropped on the porous substance (29). A current proportional to the substrate concentration flows, so it is possible to quantitatively determine the matrix concentration of various biological samples highly accurately, rapidly and easily.
摘要翻译：测量电极（27）和相邻电极（28）嵌入在绝缘衬底（26）中。电极系统的暴露表面涂覆有携带氧化还原酶（30）的多孔物质（29），如果需要，在干燥状态下涂覆电子受体（31），以形成生物传感器。在生物传感器的电极（27,28）之间施加预定的电压，将含有基质的样品滴在多孔物质（29）上。与基板浓度成比例的电流流动，因此可以高精度，快速和容易地定量地确定各种生物样品的基质浓度。

3. 发明授权

EP0359831B2 BIOSENSOR AND PROCESS FOR ITS PRODUCTION 失效
标题翻译：生物传感器及其生产
公开(公告)号：EP0359831B2
公开(公告)日：2007-06-20
申请号：EP89904212.1
申请日：1989-03-30
申请人： MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.
发明人： NANKAI, Shiro , KAWAGURI, Mariko , OHTANI, Mayumi , IIJIMA, Takashi
IPC分类号： G01N27/28 , G01N27/30 , C12M1/40 , G01N27/327
CPC分类号： G01N27/3272 , C12Q1/001 , C12Q1/004 , Y10S435/817 , Y10S436/806

4. 发明公开

EP0230472A1 BIOSENSOR AND METHOD OF MANUFACTURING SAME 失效
标题翻译：生物传感器及其生产。
公开(公告)号：EP0230472A1
公开(公告)日：1987-08-05
申请号：EP86903608.7
申请日：1986-06-19
申请人： MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.
发明人： NANKAI, Shiro , KAWAGURI, Mariko , IIJIMA, Takashi
IPC分类号： G01N27/30 , G01N27/416
CPC分类号： C12Q1/004 , Y10S435/817
摘要： The electrode systems (13, 14, 15) consisting mainly of carbon on an insulated substrate (12), and the surfaces of said electrode systems are coated with an insulating layer (16) while parts (13', 14', 15') thereof being exposed. A porous member (18), which retains oxygen and electron receptors thereon, and a retainer frame (17) are then provided on the upper surface of the resultant product. A cover (19) having an opening with the diameter smaller than that of the porous member (18) is then placed on the resultant product, and all of these parts are combined integrally. Owing to such a construction, an inexpensive disposable biosensor capable of carrying out a measuring operation easily can be obtained. When heat-treated at 60-170°C for 1-8 hours during the formation of the electrode systems, the preservation stability of the biosensor can be improved. By subjecting the surfaces of the measuring electrodes to a protein adsorption treatment, the dispersion of response currents can be prevented.

5. 发明公开

EP1231487A1 REFLECTING PLATE, METHOD FOR MANUFACTURING THE SAME, DISPLAY ELEMENT, AND DISPLAY DEVICE 审中-公开
标题翻译：反射板，相关的方法，显示元件和显示装置
公开(公告)号：EP1231487A1
公开(公告)日：2002-08-14
申请号：EP00969988.5
申请日：2000-10-23
申请人： MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.
发明人： WAKITA, Naohide , NISHIYAMA, Seiji , KAWAGURI, Mariko
IPC分类号： G02B5/04 , G02B5/02 , G02F1/1335
CPC分类号： G02B5/10
摘要： In a reflector comprising a reflecting film formed on a surface having depressions and protrusions, wherein each of the depressions and protrusions has a vertex and is composed of a curved surface formed so as to be convex up or convex down and a surrounding portion including a valley or a ridge surrounding the curved surface with an inflection point of the curved surface serving as a boundary between the curved surface and the surrounding portion; and wherein when the curved surface is convex up, the inflection point is on the valley side of the midpoint between the vertex and the valley, whereas when the curved surface is convex down, the inflection point is on the ridge side of the midpoint between the vertex and the ridge.

6. 发明公开

EP0990942A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD OF MANUFACTURING THE SAME 审中-公开
标题翻译：液晶显示器和及其方法
公开(公告)号：EP0990942A1
公开(公告)日：2000-04-05
申请号：EP99909292.7
申请日：1999-03-19
申请人： Matsushita Electric Industrial Co., Ltd.
发明人： YAMANAKA, Yasuhiko , WAKITA, Naohide , YAMAZOE, Hiroshi , KARASAWA, Takeshi , KAWAGURI, Mariko
IPC分类号： G02F1/1339 , G02F1/1347 , G02F1/1345 , G02F1/1335 , G02F1/1333
CPC分类号： G02F1/13394 , G02F1/133305 , G02F1/133377 , G02F1/133553 , G02F1/1347 , G02F2202/025
摘要： In a liquid crystal display device in which a plurality of liquid crystal layers are stacked on a substrate, a method for bonding a film for sealing liquid crystal to supporting members is improved and the fabrication cost is thereby reduced, in order to provide a reflective type liquid crystal display device that achieves a bright display image and causes no parallax problem, and to provide a reducing method of the device. The liquid crystal display device comprises a substrate, a resin film, a multiplicity of columnar supporting members, an adhesive layer, and a liquid crystal layer. The substrate comprises a pixel electrode and a driving element connected to the pixel electrode, both formed on the upper surface of the substrate. The resin film comprises a common electrode provided on the upper surface of the film, and is disposed upwardly with respect to the substrate. The supporting members are provided on the substrate so as to support the resin film. The adhesive layer is provided between each of the supporting members and the resin film so as to bond the resin film to each of the supporting members. The liquid crystal layer is produced by filling liquid crystal between the substrate and the resin film. The adhesive layer is composed of a thermoplastic material, and characterized in that a bonding state of the resin film and the supporting members is realized by making the adhesive layer have a thermoplastic characteristic.

7. 发明授权

EP0136362B1 BIOSENSOR 失效
标题翻译：生物传感器
公开(公告)号：EP0136362B1
公开(公告)日：1990-12-19
申请号：EP84901016.0
申请日：1984-03-06
申请人： MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.
发明人： KAWAGURI, Mariko , NANKAI, Shiro , IIJIMA, Takashi
IPC分类号： G01N27/327
CPC分类号： C12Q1/005 , C12Q1/004
摘要： A measuring electrode (27) and an adjacent electrode (28) are embedded in an insulating substrate (26). The exposed surface of the electrode system is coated with a porous substance (29) carrying an oxidation reductase (30) and, if needed, an electron acceptor (31) in a dry state, to form a biosensor. A predetermined voltage is applied between the electrodes (27, 28) of the biosensor, and a matrix-containing sample is dropped on the porous substance (29). A current proportional to the substrate concentration flows, so it is possible to quantitatively determine the matrix concentration of various biological samples highly accurately, rapidly and easily.

8. 发明授权

EP0230472B2 BIOSENSOR AND METHOD OF MANUFACTURING SAME 失效
标题翻译：生物传感器及其生产
公开(公告)号：EP0230472B2
公开(公告)日：2000-12-13
申请号：EP86903608.7
申请日：1986-06-19
申请人： MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.
发明人： NANKAI, Shiro , KAWAGURI, Mariko , IIJIMA, Takashi
IPC分类号： G01N27/30 , G01N27/416
CPC分类号： C12Q1/004 , Y10S435/817
摘要： The electrode systems (13, 14, 15) consisting mainly of carbon on an insulated substrate (12), and the surfaces of said electrode systems are coated with an insulating layer (16) while parts (13', 14', 15') thereof being exposed. A porous member (18), which retains oxygen and electron receptors thereon, and a retainer frame (17) are then provided on the upper surface of the resultant product. A cover (19) having an opening with the diameter smaller than that of the porous member (18) is then placed on the resultant product, and all of these parts are combined integrally. Owing to such a construction, an inexpensive disposable biosensor capable of carrying out a measuring operation easily can be obtained. When heat-treated at 60-170oC for 1-8 hours during the formation of the electrode systems, the preservation stability of the biosensor can be improved. By subjecting the surfaces of the measuring electrodes to a protein adsorption treatment, the dispersion of response currents can be prevented.

9. 发明授权

EP0359831B1 BIOSENSOR AND PROCESS FOR ITS PRODUCTION 失效
标题翻译：生物传感器及其生产。
公开(公告)号：EP0359831B1
公开(公告)日：1995-08-30
申请号：EP89904212.1
申请日：1989-03-30
申请人： MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.
发明人： NANKAI, Shiro , KAWAGURI, Mariko , OHTANI, Mayumi , IIJIMA, Takashi
IPC分类号： G01N27/28 , G01N27/30 , C12M1/40 , G01N27/327
CPC分类号： G01N27/3272 , C12Q1/001 , C12Q1/004 , Y10S435/817 , Y10S436/806
摘要： A biosensor of the invention comprises an insulating base board (1) having formed thereon, in sequence, leads (2, 3, 3'), an electrode system mainly made of carbon (4, 5, 5'), an insulating layer (6) and a reaction layer (14) composed of an enzyme and an electron acceptor, and being provided thereon with a space (8) defined by a spacer (7) and a cover (9). When a biological sample solution is brought into contact with the inlet (10) of the biosensor having the above-described structure, the sample solution is introduced into its inside, while the air within the space (8) is rapidly discharged through the outlet (11) and, at the same time, the space (8) is filled with the sample solution up to the neighborhood of the outlet. Thus, measurement can be conducted inexpensively at a high speed with a high accuracy through simple procedures without residual bubbles.

10. 发明公开

EP0359831A1 BIOSENSOR AND PROCESS FOR ITS PRODUCTION 失效
标题翻译： BIOSENSOR UND DESSEN HERSTELLUNG。
公开(公告)号：EP0359831A1
公开(公告)日：1990-03-28
申请号：EP89904212.1
申请日：1989-03-30
申请人： MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.
发明人： NANKAI, Shiro , KAWAGURI, Mariko , OHTANI, Mayumi , IIJIMA, Takashi
IPC分类号： G01N27/28 , G01N27/30 , C12M1/40 , G01N27/327
CPC分类号： G01N27/3272 , C12Q1/001 , C12Q1/004 , Y10S435/817 , Y10S436/806
摘要： A biosensor of the invention comprises an insulating base board (1) having formed thereon, in sequence, leads (2, 3, 3'), an electrode system mainly made of carbon (4, 5, 5'), an insulating layer (6) and a reaction layer (14) composed of an enzyme and an electron acceptor, and being provided thereon with a space (8) defined by a spacer (7) and a cover (9). When a biological sample solution is brought into contact with the inlet (10) of the biosensor having the above-described structure, the sample solution is introduced into its inside, while the air within the space (8) is rapidly discharged through the outlet (11) and, at the same time, the space (8) is filled with the sample solution up to the neighborhood of the outlet, Thus, measurement can be conducted inexpensively at a high speed with a high accuracy through simple procedures without residual bubbles.
摘要翻译：本发明的生物传感器包括依次形成引线（2,3,3'）的绝缘基板（1），主要由碳（4,5,5'），绝缘层（ 6）和由酶和电子受体构成的反应层（14），并且在其上设置有由间隔物（7）和盖（9）限定的空间（8）。当生物样品溶液与具有上述结构的生物传感器的入口（10）接触时，将样品溶液引入其内部，同时空间（8）内的空气通过出口（ 11），并且同时，空间（8）填充有样品溶液直到出口附近。因此，通过没有残留气泡的简单程序，可以高精度地以高速度廉价地进行测量。

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