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1. 发明授权

EP0424790B1 Multi-dose inhaler for medicaments in powder form 失效
标题翻译：多剂量吸入剂用于粉末形式的药物
公开(公告)号：EP0424790B1
公开(公告)日：1993-08-04
申请号：EP90119877.0
申请日：1990-10-17
申请人： MIAT S.P.A.
发明人： Cocozza, Salvatore
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0071 , A61M2202/064

2. 发明授权

EP0518087B1 Multi-dose insufflator for medicaments in powder form 失效
标题翻译：吹的粉末药物多剂量。
公开(公告)号：EP0518087B1
公开(公告)日：1995-07-19
申请号：EP92108490.1
申请日：1992-05-20
申请人： MIAT S.P.A.
发明人： Cocozza, Salvatore
IPC分类号： A61M15/00 , B05B7/14 , G01F11/24
CPC分类号： B05B11/067 , A61M15/0065 , A61M15/08 , A61M2202/064 , A61M2205/075 , B05B11/062 , G01F11/24

3. 发明授权

EP0303844B1 Insufflator for the administration of drugs in the form of a powder pre-dosed into opercula 失效
标题翻译：用于预处理粉末形式的药物管理的消除者
公开(公告)号：EP0303844B1
公开(公告)日：1991-05-22
申请号：EP88111680.0
申请日：1988-07-20
申请人： MIAT S.P.A.
发明人： Cocozza, Salvatore
IPC分类号： A61M13/00
CPC分类号： A61M15/0028 , A61M15/0033 , A61M2202/064 , A61M2205/075

4. 发明公开

EP0518087A1 Multi-dose insufflator for medicaments in powder form 失效
标题翻译： EinblasgerätfürMehrfachdosierungen vonfredrörmigenMedikamenten。
公开(公告)号：EP0518087A1
公开(公告)日：1992-12-16
申请号：EP92108490.1
申请日：1992-05-20
申请人： MIAT S.P.A.
发明人： Cocozza, Salvatore
IPC分类号： A61M15/00 , B05B7/14 , G01F11/24
CPC分类号： B05B11/067 , A61M15/0065 , A61M15/08 , A61M2202/064 , A61M2205/075 , B05B11/062 , G01F11/24
摘要： A multi-dose insufflator for the nasal administration of medicaments in fine or micronized powder form comprises a reservoir unit (34), a unit (60, 64) for withdrawing and metering the medicament contained in the reservoir unit, and an insufflation unit (42, 26) comprising a manually operated pump (42) for generating an air stream within a channel (26) for conveying an individual dose of medicament into the nasal cavity of the patient. The withdrawal and metering unit comprises a conveyor device (60) provided with at least one cup (64) for withdrawing a dose of medicament from the reservoir (34) and conveying it into an insufflation position. The cup (64) has a coaxial base hole (66) through which the air stream generated by the pump passes when the cup is in the insufflation position. The hole (66) has a size substantially smaller than the mouth of the cup (64) and such as to prevent the powder medicament falling through the hole, by virtue of the "arching" effect.
摘要翻译：用于以微细或微粉化形式的鼻部给药的多剂量吹入器包括储存器单元（34），用于抽出和计量储存器单元中包含的药物的单元（60,64）和吹气单元（42），26）包括用于在通道（26）内产生空气流的手动操作的泵（42），用于将单个剂量的药物输送到患者的鼻腔中。抽出和计量单元包括设置有至少一个杯（64）的输送装置（60），用于从储存器（34）中取出剂量的药剂并将其输送到吹入位置。杯（64）具有同轴底孔（66），当杯处于吹气位置时，由泵产生的空气流通过该孔。该孔（66）的尺寸基本上小于杯（64）的口部，并且借助于“拱形”效应来防止粉末药物从孔中掉落。

5. 发明公开

EP0424790A2 Multi-dose inhaler for medicaments in powder form 失效
标题翻译：多功能粉碎机在粉煤灰中的应用。
公开(公告)号：EP0424790A2
公开(公告)日：1991-05-02
申请号：EP90119877.0
申请日：1990-10-17
申请人： MIAT S.P.A.
发明人： Cocozza, Salvatore
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0071 , A61M2202/064
摘要： A multi-dose inhaler (1; 2) for medicaments in powder form comprises a container unit (24; 124) for the medicament in powder form, a withdrawal and dose preparation unit (22, 26; 122, 126) for said medicament, and a unit (16, 50; 152, 176) for mixing the dose of medicament with an air stream. The withdrawal and dose preparation unit comprises: a cup-type conveyor device (22; 122) provided with at least one cup (20; 120) for withdrawing from the container unit a certain quantity of powder and conveying it into a dispensing position, the cup (20; 120) having two coaxial identical holes (56; 156); and a plunger-type dispensing device (36; 106) disposed above the mixing unit, the plunger (36; 106) being insertable as an exact fit into and withdrawable from the holes (56; 156) in the cup (20; 120) when this latter is in the dispensing position, to cause a dose of medicament in powder form to fall into the mixing unit.
摘要翻译：用于粉末形式的药物的多剂量吸入器（1; 2）包括用于药物粉末形式的容器单元（24; 124），用于所述药物的抽出剂量制剂单元（22,26; 122,126）以及用于将剂量的药物与空气流混合的单元（16,50; 152,176）。提取和剂量制备单元包括：杯形输送装置（22; 122），其设置有至少一个杯子（20; 120），用于从容器单元中取出一定量的粉末并将其输送到分配位置，具有两个同轴相同孔（56; 156）的杯（20; 120）; 以及设置在所述混合单元上方的柱塞式分配装置（36; 106），所述柱塞（36; 106）可精确地配合到所述杯体（20; 120）中的孔（56; 156）当后者处于分配位置时，导致一定剂量的粉末形式的药物落入混合单元中。

6. 发明公开

EP0424790A3 Multi-dose inhaler for medicaments in powder form 失效
标题翻译：多剂量吸入剂用于粉末形式的药物
公开(公告)号：EP0424790A3
公开(公告)日：1991-11-21
申请号：EP90119877.0
申请日：1990-10-17
申请人： MIAT S.P.A.
发明人： Cocozza, Salvatore
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0071 , A61M2202/064
摘要： A multi-dose inhaler (1; 2) for medicaments in powder form comprises a container unit (24; 124) for the medicament in powder form, a withdrawal and dose preparation unit (22, 26; 122, 126) for said medicament, and a unit (16, 50; 152, 176) for mixing the dose of medicament with an air stream. The withdrawal and dose preparation unit comprises: a cup-type conveyor device (22; 122) provided with at least one cup (20; 120) for withdrawing from the container unit a certain quantity of powder and conveying it into a dispensing position, the cup (20; 120) having two coaxial identical holes (56; 156); and a plunger-type dispensing device (36; 106) disposed above the mixing unit, the plunger (36; 106) being insertable as an exact fit into and withdrawable from the holes (56; 156) in the cup (20; 120) when this latter is in the dispensing position, to cause a dose of medicament in powder form to fall into the mixing unit.
摘要翻译：用于粉末形式的药物的多剂量吸入器（1; 2）包括用于药物粉末形式的容器单元（24; 124），用于所述药物的抽出剂量制剂单元（22,26; 122,126）以及用于将剂量的药物与气流混合的单元（16,50; 152,176）。抽出剂量制备单元包括：杯形输送装置（22; 122），其设置有至少一个杯子（20; 120），用于从容器单元中取出一定量的粉末并将其输送到分配位置，具有两个同轴相同孔（56; 156）的杯（20; 120）; 以及设置在所述混合单元上方的柱塞型分配装置（36; 106），所述柱塞（36; 106）可精确地插入并可从杯体（20; 120）中的孔（56; 156）中抽出，当后者处于分配位置时，导致一定剂量的粉末形式的药物落入混合单元中。

7. 发明公开

EP0303844A1 Insufflator for the administration of drugs in the form of a powder pre-dosed into opercula 失效
标题翻译：在Kapseln vordosierter Medikamente的吸入器zum Verabreichenpowderförmiger。
公开(公告)号：EP0303844A1
公开(公告)日：1989-02-22
申请号：EP88111680.0
申请日：1988-07-20
申请人： MIAT S.P.A.
发明人： Cocozza, Salvatore
IPC分类号： A61M13/00
CPC分类号： A61M15/0028 , A61M15/0033 , A61M2202/064 , A61M2205/075
摘要： An insufflator for administering pre-dosed powder drugs contained in opercula, which comprises a body (6) having an air-inlet opening (7) and a substantially vertical outlet channel (8) for the air carrying the powder drug, and a device with opposite pins (18,19) of a known kind for puncturing the operculum (15), said operculum (15) being placed in a suitable seat (14). The latter is provided in a member (13) that is turnable relative to said body (6). Said turnable member can take at least two different positions: a first position, where the operculum (15) can be axially punctured by the above-mentioned opposite, substantially horizontal pins (18,19); and a second position, turned 90° relative to said first position, where the opposite holes that have been pierced in the operculum (15) are coaxial with said air-outlet channel (8).
摘要翻译：一种用于施用包含在手术中的预给药粉末药物的吹入器，其包括具有进气口（7）的主体（6）和用于携带粉末药物的空气的基本上垂直的出口通道（8）已知类型的针刺（15,19）的相对的销（18,19），所述操纵件（15）被放置在合适的座（14）中。后者设置在相对于所述主体（6）可转动的构件（13）中。所述可转动构件可以采取至少两个不同的位置：第一位置，其中所述操纵件（15）可以被上述相对的基本上水平的销（18,19）轴向地刺穿; 以及相对于所述第一位置转动90度的第二位置，其中在所述操纵部（15）中刺穿的相对的孔与所述出气通道（8）同轴。

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