专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP4089180A1 MULTIPURPOSE COMPOSITIONS FOR COLLECTING AND TRANSPORTING BIOLOGICAL MATERIAL 审中-实审
公开(公告)号：EP4089180A1
公开(公告)日：2022-11-16
申请号：EP22182987.2
申请日：2020-09-02
申请人： Longhorn Vaccines and Diagnostics, LLC
发明人： DAUM, Luke T. , FISCHER, Gerald W.
IPC分类号： C12Q1/6806
摘要： The invention is directed to compositions and methods for collecting, transporting, and storing, without refrigeration, biological materials, which may comprise samples of biological, clinical, forensic, and/or environmental origin. These compositions preserve the viability of the collected organisms and/or the RNA/DNA and proteins in the sample composition mixture and permit the long-term storage of samples. Compositions are compatible with subsequent manipulation of the sample, including propagation and culture of the collected microorganisms, or isolation, purification, detection, and characterization of proteins, nucleic acids, and other macromolecules. When the compositions containing microorganisms and any polynucleotides therein are further processed, such as by nucleic acid testing, there is an increased ability to detect, isolate, purify and/or characterize select microbes and their components, such as nucleic acids, when compared to conventional microbial transport media that contain interfering substances and RNA/DNA extraction is not required prior to PCR analysis. In particular, the compositions disclosed allow for the collection, transport and storage of biological samples for extended periods at ambient temperature, while maintaining the integrity of the macromolecules of the sample for subsequent extraction, identification, and quantitation.

2. 发明公开

EP4031649A1 MULTIPURPOSE COMPOSITIONS FOR COLLECTING AND TRANSPORTING BIOLOGICAL MATERIAL 审中-实审
公开(公告)号：EP4031649A1
公开(公告)日：2022-07-27
申请号：EP20864758.6
申请日：2020-09-02
申请人： Longhorn Vaccines and Diagnostics, LLC
发明人： DAUM, Luke T. , FISCHER, Gerald W.
IPC分类号： C12N1/04 , C12N1/20 , C12N1/00 , G01N1/10 , G01N33/487 , G01N33/48

3. 发明公开

EP3086805A2 MULTIMODAL ANTIMICROBIAL THERAPY 有权
标题翻译： MULTIMODALE抗血小板治疗
公开(公告)号：EP3086805A2
公开(公告)日：2016-11-02
申请号：EP14874375.0
申请日：2014-12-29
申请人： Longhorn Vaccines and Diagnostics, LLC
发明人： FISCHER, Gerald W. , SCHUMAN, Richard F.
IPC分类号： A61K38/43 , A61K38/48 , C12N9/52 , G01N33/569
CPC分类号： A61K38/4886 , A61K9/0073 , A61K9/16 , A61K9/50 , A61K45/06 , A61L29/16 , A61L31/16 , A61L2300/254 , A61L2300/404 , A61L2300/45 , A61P31/00 , A61P31/06 , C12N9/6489 , C12Y304/24075 , Y02A50/473
摘要： The present invention is directed to compositions and methods for preventing and/or treating diseases and disorders of patients caused by non-Staphylococcal microorganisms. In particular, compositions and methods contain lysostaphin, altered forms of lysostaphin as compared to wild-type, and synergistic combinations of lysostaphin plus additional conventional treatments such as other enzyme, antibiotic and/or antibody treatment. The invention is also directed to detecting and identifying altered forms of lysostaphin that possess increased efficacy against infections as compared to wild-type lysostaphin, and forms that generate a minimal or no immune response in a patient. The invention is also directed to method of manufacturing lysostaphin and altered forms of lysostaphin, and compositions that direct the lysostaphin to the site of the infection such as aerosolized nanoparticles.
摘要翻译：本发明涉及用于预防和/或治疗由非葡萄球菌微生物引起的患者疾病和病症的组合物和方法。特别地，组合物和方法含有溶葡萄球菌素，与野生型相比的溶葡萄球菌素的改变形式，以及溶葡萄球菌素加其他常规治疗如其它酶，抗生素和/或抗体治疗的协同组合。本发明还涉及检测和鉴定与野生型溶葡萄球菌素相比具有增强的感染效力的溶葡萄球菌的改变形式，以及在患者中产生最小或无免疫应答的形式。本发明还涉及制备溶葡萄球菌素和改变形式的溶葡萄球菌素的方法，以及将溶葡萄球菌引导至感染部位如烟雾化纳米粒子的组合物。

4. 发明公开

EP3877550A1 RAPID PCR METHODOLOGY 审中-实审
公开(公告)号：EP3877550A1
公开(公告)日：2021-09-15
申请号：EP19881198.6
申请日：2019-10-31
申请人： Longhorn Vaccines and Diagnostics, LLC
发明人： DAUM, Luke T. , FISCHER, Gerald W.
IPC分类号： C12Q1/689

5. 发明公开

EP3494989A1 COMPOSITE ANTIGENIC SEQUENCES AND VACCINES 审中-公开
公开(公告)号：EP3494989A1
公开(公告)日：2019-06-12
申请号：EP18204631.8
申请日：2013-01-25
申请人： Longhorn Vaccines and Diagnostics, LLC
发明人： FISCHER, Gerald W. , DAUM, Luke T.
IPC分类号： A61K39/145
摘要： The invention relates to composite antigens comprising a peptide with contiguous amino acid sequence derived from a plurality of antigenic epitopes of one or more pathogens that induces an immune response in a mammal that is protective against infection by the one or more pathogens. In addition, the invention relates to vaccines comprising composite antigens and to method for treating and preventing an infection.

6. 发明公开

EP3781702A1 RAPID METHODS FOR THE DETECTION OF MICROBIAL RESISTANCE 审中-实审
公开(公告)号：EP3781702A1
公开(公告)日：2021-02-24
申请号：EP19789050.2
申请日：2019-04-19
申请人： Longhorn Vaccines and Diagnostics, LLC
发明人： DAUM, Luke T. , FISCHER, Gerald W.
IPC分类号： C12Q1/18 , G01N30/72 , G01N30/88

7. 发明公开

EP3038648A2 ENHANCING IMMUNITY TO TUBERCULOSIS 无效
标题翻译：加强与结核病的抗扰度
公开(公告)号：EP3038648A2
公开(公告)日：2016-07-06
申请号：EP14839667.4
申请日：2014-08-29
申请人： Longhorn Vaccines and Diagnostics, LLC
发明人： FISCHER, Gerald W. , DAUM, Luke T. , SEI, Clara Jabet
IPC分类号： A61K39/04 , C07K14/35
CPC分类号： A61K39/04 , A61K39/12 , A61K39/40 , A61K2039/521 , A61K2039/55505 , A61K2039/55566 , A61K2039/575 , A61K2039/6037 , A61K2039/6081 , A61K2039/70 , C07K14/35 , C07K16/1289 , C07K2317/73 , C07K2319/00 , C07K2319/31 , C12N2760/16134 , G01N33/5055
摘要： The invention is directed to compositions and methods for generating or enhancing the immune system of a patient against infection by a pathogen, and in particular MTB. Compositions of the invention contain one or more non-naturally occurring antigens that generate an effective cellular or humoral immune response to MTB and/or antibodies that are specifically reactive to mycolic acid or to the surface of MTB. The greater activity of the immune system generated by a vaccine of the invention involve an conjugation of peptides to increase in the generation of memory T cells that provide for a greater and/or longer lived or extended response to an MTB infection. Preferably a response involves an increased generation of antibodies that enhance immunity against MTB infection and promote an enhanced phagocytic response.

9. 发明公开

EP4288111A1 MULTIPURPOSE COMPOSITIONS FOR COLLECTING AND TRANSPORTING BIOLOGICAL MATERIAL 审中-实审
公开(公告)号：EP4288111A1
公开(公告)日：2023-12-13
申请号：EP22750167.3
申请日：2022-01-19
申请人： Longhorn Vaccines and Diagnostics, LLC
发明人： DAUM, Luke T. , FISCHER, Gerald W.
IPC分类号： A61K47/69 , C07K14/00 , C07K14/005

10. 发明公开

EP4100058A1 IMMUNOGENIC COMPOSITIONS TO TREAT AND PREVENT MICROBIAL INFECTIONS 审中-实审
公开(公告)号：EP4100058A1
公开(公告)日：2022-12-14
申请号：EP21750004.0
申请日：2021-01-29
申请人： Longhorn Vaccines and Diagnostics, LLC
发明人： DAUM, Luke T. , FISCHER, Gerald W. , SEI, Clara J.
IPC分类号： A61K39/39 , A61K39/00 , A61K39/12 , A61K39/145

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式