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    • 4. 发明公开
    • WHITE BLOOD CELL MONITORING DURING TREATMENT CYCLES
    • ÜBERWACHUNGWEISSER BLUTZELLENWÄHRENDBEHANDLUNGSZYKLEN
    • EP2890985A1
    • 2015-07-08
    • EP13786754.5
    • 2013-08-26
    • Koninklijke Philips N.V.
    • VAN BERKEL, Cees
    • G01N33/569G06F19/00
    • This application relates to methods and apparatus for monitoring and predicting a cell count of at least one component of white blood cells, especially absolute neutrophil count (ANC), within a chemotherapy treatment cycle. The method comprises taking (102), within a treatment cycle, at least one measurement of a cell count of said white blood cell component of a subject; identifying (103) at least one modeled trajectory of white blood cell count that matches said at least one measurement for said subject; and based on said at least one modeled trajectory identifying (104) a likely cell count at a later date in the cycle and/or start of the next cycle. The step of identifying at least one modeled trajectory may comprise taking a reference set of trajectories that has been generated (101), and from said reference set, identifying a selection set of trajectories that matches the measurement data.
    • 本申请涉及用于在化学治疗周期内监测和预测白细胞的至少一种成分(特别是绝对中性粒细胞计数(ANC))的细胞计数的方法和装置。 所述方法包括在治疗周期内取(102)至少一次测量受试者所述白细胞组分的细胞计数; 识别(103)与所述受试者的所述至少一个测量相匹配的白细胞计数的至少一个建模轨迹; 并且基于所述至少一个建模轨迹,其识别(104)循环中的稍后日期和/或下一周期开始的可能的细胞计数。 识别至少一个建模轨迹的步骤可以包括获取已经生成的参考轨迹轨迹(101),并且从所述参考集合识别与测量数据匹配的轨迹的选择集合。