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1. 发明公开

EP2613146A1 METHOD FOR ASSAYING FIBROBLAST GROWTH FACTOR-23 AND ASSAY REAGENT 有权
标题翻译： PROCEDURE用于确定所述成纤维细胞生长因子23和ENSURE测定试剂
公开(公告)号：EP2613146A1
公开(公告)日：2013-07-10
申请号：EP11821852.8
申请日：2011-08-31
申请人： KYOWA MEDEX CO., LTD.
发明人： UZAWA, Koji , SUZUKI, Emiko , IKEDA, Kazuyuki , MORITA, Kazuki
IPC分类号： G01N33/53 , G01N33/543
CPC分类号： G01N33/74 , G01N33/54326 , G01N2333/50
摘要： A method for measuring fibroblast growth factor-23 (FGF-23) in a sample, which comprise the following steps:
(1) reacting, in an aqueous medium, FGF-23 in a sample with magnetic particles, a first antibody or a fragment thereof which binds to FGF-23, and a second antibody or a fragment thereof which binds to FGF-23, to form on the magnetic particles an immunocomplex comprising the first antibody or a fragment thereof which binds to FGF-23, FGF-23, and the second antibody or a fragment thereof which binds to FGF-23;
(2) collecting the magnetic particles in the reaction mixture after step (1) by magnetic force, and separating the magnetic particles collected by magnetic force from the other components; and
(3) measuring the immunocomplex on the magnetic particles separated in step (2).
The present invention provides a method for measuring FGF-23 in a sample, which have a high sensitivity and have a wide measurement range.

2. 发明公开

EP2309264A1 DEVICE FOR DETECTION OF INFLUENZA VIRUS 审中-公开
标题翻译： GRIPPEVIRUSNACHWEISVORRICHTUNG
公开(公告)号：EP2309264A1
公开(公告)日：2011-04-13
申请号：EP09758417.1
申请日：2009-06-05
申请人： National University Corporation University Of Toyama , SC World Inc. , Kyowa Medex CO., LTD.
发明人： MURAGUCHI, Atsushi , KISHI, Hiroyuki , OZAWA, Tatsuhiko , IKEMOTO, Mamoru , ONO, Hitoshi , MORITA, Kazuki , UZAWA, Koji
IPC分类号： G01N33/543 , C07K16/10 , G01N33/53 , G01N33/569 , C12N15/09 , C12P21/08
CPC分类号： C07K16/1018 , C07K2317/21 , C07K2317/33 , C07K2319/61 , G01N33/558 , G01N33/56983 , G01N2333/11
摘要： A device for detecting or quantifying influenza viruses in a sample, which comprises a detection region having a human anti-influenza virus nucleoprotein antibody immobilized onto a support, a sample supply region, and a sample-migrating region; and a kit for detecting or quantifying influenza viruses, which comprises a solid phase in which a human anti-influenza virus nucleoprotein antibody is fixed onto a carrier.
摘要翻译：一种用于检测或定量样品中的流感病毒的装置，其包含检测区域，其具有固定在载体上的人类抗流感病毒核蛋白抗体，样品供应区域和样品迁移区域; 以及用于检测或定量流感病毒的试剂盒，其包含将抗人流感病毒核蛋白抗体固定在载体上的固相。

3. 发明授权

EP3101423B1 METHOD FOR MEASURING FIBROBLAST GROWTH FACTOR-23 AND REAGENT THEREFOR 有权
公开(公告)号：EP3101423B1
公开(公告)日：2019-04-03
申请号：EP16176905.4
申请日：2011-08-31
申请人： KYOWA MEDEX CO., LTD.
发明人： UZAWA, Koji , SUZUKI, Emiko , IKEDA, Kazuyuki , MORITA, Kazuki
IPC分类号： G01N33/543 , G01N33/74

4. 发明公开

EP3101423A1 METHOD FOR MEASURING FIBROBLAST GROWTH FACTOR-23 AND REAGENT THEREFOR 有权
标题翻译： VERFAHREN ZUR MESSUNG VON FIBROBLASTENWACHSTUMSFAKTOR-23 UND REAGENSDAFÜR
公开(公告)号：EP3101423A1
公开(公告)日：2016-12-07
申请号：EP16176905.4
申请日：2011-08-31
申请人： KYOWA MEDEX CO., LTD.
发明人： UZAWA, Koji , SUZUKI, Emiko , IKEDA, Kazuyuki , MORITA, Kazuki
IPC分类号： G01N33/543 , G01N33/74
CPC分类号： G01N33/74 , G01N33/54326 , G01N2333/50
摘要： A method for measuring fibroblast growth factor-23 (FGF-23) in a sample, which comprise the following steps:
(1) reacting, in an aqueous medium, FGF-23 in a sample with magnetic particles, a first antibody or a fragment thereof which binds to FGF-23, and a second antibody or a fragment thereof which binds to FGF-23, to form on the magnetic particles an immunocomplex comprising the first antibody or a fragment thereof which binds to FGF-23, FGF-23, and the second antibody or a fragment thereof which binds to FGF-23;
(2) collecting the magnetic particles in the reaction mixture after step (1) by magnetic force, and separating the magnetic particles collected by magnetic force from the other components; and
(3) measuring the immunocomplex on the magnetic particles separated in step (2).
The present invention provides a method for measuring FGF-23 in a sample, which have a high sensitivity and have a wide measurement range.
摘要翻译：（1）在水性介质中使样品中的FGF-23与磁性颗粒，第一抗体或片段（FGF-23）在一个样品中测量成纤维细胞生长因子-23（FGF-23）其与FGF-23结合，以及结合FGF-23的第二抗体或其片段，在磁性颗粒上形成包含与FGF-23，FGF-23结合的第一抗体或其片段的免疫复合物，和与FGF-23结合的第二抗体或其片段; （2）通过磁力在步骤（1）之后收集反应混合物中的磁性颗粒，并将通过磁力收集的磁性颗粒与其它组分分离; 和（3）测量在步骤（2）中分离的磁性颗粒上的免疫复合物。本发明提供了一种用于测量样品中的FGF-23的方法，其具有高灵敏度并且具有宽的测量范围。

5. 发明授权

EP2613146B1 METHOD FOR MEASURING FIBROBLAST GROWTH FACTOR-23 AND REAGENT THEREFOR 有权
标题翻译：测量成纤维细胞生长因子-23的方法和试剂
公开(公告)号：EP2613146B1
公开(公告)日：2017-06-28
申请号：EP11821852.8
申请日：2011-08-31
申请人： KYOWA MEDEX CO., LTD.
发明人： UZAWA, Koji , SUZUKI, Emiko , IKEDA, Kazuyuki , MORITA, Kazuki
IPC分类号： G01N33/543 , G01N33/74
CPC分类号： G01N33/74 , G01N33/54326 , G01N2333/50

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