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1. 发明公开

EP2259833A1 METHODS AND APPARATUS FOR TREATING GLAUCOMA 审中-公开
标题翻译：方法和一种用于治疗青光眼
公开(公告)号：EP2259833A1
公开(公告)日：2010-12-15
申请号：EP09718091.3
申请日：2009-03-05
申请人： Ivantis, INC.
发明人： EUTENEUER, Charles, L. , HEKTNER, Thomas, R. , SCHIEBER, Andrew, T. , WARDLE, John
IPC分类号： A61M27/00
CPC分类号： A61F9/00781 , A61F9/0017 , A61F9/007 , A61F2009/00885 , A61F2009/00891 , A61K9/0051 , A61M27/002 , A61M2210/0612 , Y10S623/905 , Y10S623/906
摘要： An ocular implant for treating glaucoma is provided, which may include any number of features. More particularly, the present invention relates to implants that facilitate the transfer of fluid from within one area of the eye to another area of the eye. One feature of the implant is that it includes a proximal inlet portion and a distal inlet portion adapted to be inserted into the anterior chamber of the eye, and an intermediate portion adapted to be inserted into Schlemm's canal. Another feature of the implant is that it can be biased to assume a predetermined shape to aid in placement within the eye.

2. 发明公开

EP2838584A1 OCULAR IMPLANTS FOR DELIVERY INTO AN ANTERIOR CHAMBER OF THE EYE 有权转让
标题翻译： EYE植入物分布在眼睛前室
公开(公告)号：EP2838584A1
公开(公告)日：2015-02-25
申请号：EP13778216.5
申请日：2013-04-15
申请人： Ivantis, Inc.
发明人： WARDLE, John , SCHIEBER, Andrew, T.
IPC分类号： A61M5/00
CPC分类号： A61F9/00781
摘要： An ocular implant adapted to be disposed within Schlemm's canal of a human eye with a body extending along a curved longitudinal central axis in a curvature plane, a first strut on one side of the implant and a second strut on an opposite side of the implant, the circumferential extent of the first strut with respect to the plane of curvature being greater than the circumferential extent of the second strut with respect to the plane of curvature. The invention also includes methods of using the implant.

3. 发明公开

EP2389138A1 METHODS AND APPARATUS FOR DELIVERING OCULAR IMPLANTS INTO THE EYE 有权转让
标题翻译：方法和设备眼植入物的眼睛释放
公开(公告)号：EP2389138A1
公开(公告)日：2011-11-30
申请号：EP09831277.0
申请日：2009-12-07
申请人： Ivantis, INC.
发明人： SCHIEBER, Andrew, T. , WARDLE, John , MATTHEES, Edward
IPC分类号： A61F2/16
CPC分类号： A61F9/00781 , A61M25/0068 , A61M25/01 , A61M31/00 , A61M2025/0004
摘要： A method of deploying an ocular implant into Schlemm's canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into Schlemm's canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in Schlemm's canal and an inlet portion of the ocular implant in the anterior chamber.

4. 发明公开

EP2194941A2 OCULAR IMPLANTS AND METHODS 有权转让
标题翻译：眼部植入物
公开(公告)号：EP2194941A2
公开(公告)日：2010-06-16
申请号：EP08833245.7
申请日：2008-09-23
申请人： Ivantis, Inc.
发明人： SCHIEBER, Andrew, T. , EUTENEUER, Charles, L.
IPC分类号： A61F9/007
CPC分类号： A61F9/00781
摘要： An ocular implant (100) adapted to reside at least partially in a portion of Schlemm' s canal (38) of an eye (20). In some embodiments the implant has a body (104) extending in a curved volume whose longitudinal axis forms an arc of a circle, and a plurality of open areas and strut areas formed in the body (104), the open areas extending over more than 50% of a surface defining the curved volume, the strut areas surrounding the open areas, the body having a diameter of between 0.005 inches and 0.04 inches. The application also provides a method of treating glaucoma including the steps of supporting tissue forming Schlemm' s canal in an eye with an implant extending at least partially in the canal along an axial length within the canal; and contacting with the implant less than 50% of the tissue forming the canal along the axial length.

5. 发明授权

EP2838584B1 OCULAR IMPLANTS FOR DELIVERY INTO THE SCHLEMM'S CANAL 有权转让
公开(公告)号：EP2838584B1
公开(公告)日：2019-02-27
申请号：EP13778216.5
申请日：2013-04-15
申请人： Ivantis, Inc.
发明人： WARDLE, John , SCHIEBER, Andrew, T.
IPC分类号： A61F9/007

6. 发明公开

EP2763625A1 DELIVERING OCULAR IMPLANTS INTO THE EYE 有权转让
标题翻译：眼部植入物的眼睛释放
公开(公告)号：EP2763625A1
公开(公告)日：2014-08-13
申请号：EP12859635.0
申请日：2012-12-19
申请人： Ivantis, Inc.
发明人： WARDLE, John , SCHIEBER, Andrew, T.
IPC分类号： A61F2/14
CPC分类号： A61F9/0026 , A61B17/3421 , A61B17/3468 , A61B2017/3454 , A61F9/0017 , A61F9/00781 , A61F2220/0033
摘要： A system comprising: a cannula (108) having a side wall (183,184) defining a passageway, the cannula having a curved distal portion (185) extending between a distal end and a proximal portion along a radius of curvature, the cannula including an opening (132); the opening fluidly communicating with the passageway; an ocular implant (150) disposed inside the passageway defined by the cannula; and a delivery tool (152) having a distal interlocking portion (160) engaging a complementary interlocking portion (162) of the ocular implant to form a mechanically interlocking connection; the opening extending through the distal end and the side wall to form a trough portion (189); and the mechanically interlocking connection forming when the interlocking portion of the delivery tool is proximal to the trough portion of the cannula, the delivery tool distal interlocking portion having a curved at-rest shape having a smaller radius of curvature than the radius of curvature of the cannula distal portion, the cannula side wall preventing the delivery tool distal interlocking portionfrom assuming its at-rest shape when the delivery tool distal interlocking portion is proximal to the trough portion of the cannula.

7. 发明授权

EP2219570B1 OCULAR IMPLANT DELIVERY SYSTEM 有权转让
标题翻译：眼部植入供应系统
公开(公告)号：EP2219570B1
公开(公告)日：2013-06-26
申请号：EP08851890.7
申请日：2008-11-12
申请人： Ivantis, Inc.
发明人： FRION, Duane , MCCARVILLE, Rebecca , SCHIEBER, Andrew, T. , ZENZ-OLSON, Nathaniel , FEEHAN, Diane , MATTHEES, Edward , EUTENEUER, Charles, L.
IPC分类号： A61F9/007
CPC分类号： A61F9/00781

8. 发明公开

EP2451503A1 OCULAR IMPLANTS AND METHODS FOR DELIVERING OCULAR IMPLANTS INTO THE EYE 有权转让
标题翻译：眼睛植入物和方法眼部植入物的眼睛释放
公开(公告)号：EP2451503A1
公开(公告)日：2012-05-16
申请号：EP10797945.2
申请日：2010-07-09
申请人： Ivantis, INC.
发明人： WARDLE, John , SCHIEBER, Andrew, T. , GALT, Kenneth, M.
IPC分类号： A61M5/00
CPC分类号： A61F9/0017 , A61F9/0026 , A61F9/00781
摘要： An ocular implant is provided. In some embodiments, the ocular implant includes a body that is curved about a longitudinal central axis and a distal body portion that defines a longitudinal channel including a channel opening. The implant is sized and configured such that the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm's canal when the ocular implant is disposed in Schlemm's canal. Methods for delivering ocular implants into Schlemm's canal are also provided. Some methods include covering openings in the ocular implant, advancing the implant into Schlemm's canal while at least some of the openings are covered, and uncovering the openings while the distal portion of the implant is disposed in Schlemm's canal.

9. 发明公开

EP3960135A1 APPARATUS FOR DELIVERING OCULAR IMPLANTS INTO THE EYE 审中-实审转让
公开(公告)号：EP3960135A1
公开(公告)日：2022-03-02
申请号：EP21190332.3
申请日：2009-12-07
申请人： Ivantis, Inc.
发明人： SCHIEBER, Andrew, T. , WARDLE, John , MATTHEES, Edward
IPC分类号： A61F9/007 , A61M25/00 , A61M31/00 , A61M25/01
摘要： A cannula for an ocular implant delivery system. In some embodiments, the cannula includes a tubular member having a curved portion, a distal opening surrounded by a distal opening surface, and a distal tip, the distal tip being adapted to be inserted into an anterior chamber of a human subject's eye, through trabecular meshwork and into Schlemm's canal of the eye, a proximal portion of the tubular member being adapted to extend from a location exterior to the eye when the distal tip is in Schlemm's canal of the eye, the cannula being further adapted to cooperate with an advancement mechanism to advance an ocular implant through the tubular member toward and through the distal opening into Schlemm's canal of the eye when the distal tip is disposed in Schlemm's canal. The invention also includes a method of deploying an ocular implant into Schlemm's canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into Schlemm's canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in Schlemm's canal and an inlet portion of the ocular implant in the anterior chamber.

10. 发明授权

EP2451503B1 OCULAR IMPLANTS AND METHODS FOR DELIVERING OCULAR IMPLANTS INTO THE EYE 有权转让
公开(公告)号：EP2451503B1
公开(公告)日：2018-10-24
申请号：EP10797945.2
申请日：2010-07-09
申请人： Ivantis, Inc.
发明人： WARDLE, John , SCHIEBER, Andrew, T. , GALT, Kenneth, M.
IPC分类号： A61F9/007
CPC分类号： A61F9/0017 , A61F9/0026 , A61F9/00781
摘要： An ocular implant is provided. In some embodiments, the ocular implant includes a body that is curved about a longitudinal central axis and a distal body portion that defines a longitudinal channel including a channel opening. The implant is sized and configured such that the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm's canal when the ocular implant is disposed in Schlemm's canal. Methods for delivering ocular implants into Schlemm's canal are also provided. Some methods include covering openings in the ocular implant, advancing the implant into Schlemm's canal while at least some of the openings are covered, and uncovering the openings while the distal portion of the implant is disposed in Schlemm's canal.

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