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1. 发明授权

EP2841160B1 APPARATUS AND METHOD FOR HADRON BEAM VERIFICATION 有权
标题翻译：用于HADRON光束验证的装置和方法
公开(公告)号：EP2841160B1
公开(公告)日：2018-04-11
申请号：EP13719498.1
申请日：2013-04-24
申请人： ION BEAM APPLICATIONS S.A.
发明人： DESSY, Frédéric , CLAEREBOUDT, Yves
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61N5/1071 , A61N5/1075 , A61N5/1078 , A61N2005/1061 , A61N2005/1076 , A61N2005/1087
摘要： The present invention is related to an apparatus and method for hadron beam verification. The apparatus allows to verify a number of different characteristics in a brief time span. The apparatus comprises at least one main degrader element and associated therewith a multiple thickness degrader element. The latter may comprise a number of patches of beam degrading material, the patches having constant but mutually different thicknesses. Alternatively, it may be a wedge-shaped element. By aiming a pencil beam at the various thicknesses, data points can be obtained which allow to make an estimation of the beam range. In addition to this, the apparatus comprises a zone where no degrader material is present, and where a measurement of the spot size can be obtained, without moving or replacing the apparatus.

2. 发明公开

EP2841160A1 APPARATUS AND METHOD FOR HADRON BEAM VERIFICATION 有权
标题翻译： VORRICHTUNG UND VERFAHREN ZUR HADRONSTRAHLVERIFIZIERUNG
公开(公告)号：EP2841160A1
公开(公告)日：2015-03-04
申请号：EP13719498.1
申请日：2013-04-24
申请人： ION BEAM APPLICATIONS S.A.
发明人： DESSY, Frédéric , CLAEREBOUDT, Yves
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61N5/1071 , A61N5/1075 , A61N5/1078 , A61N2005/1061 , A61N2005/1076 , A61N2005/1087
摘要： The present invention is related to an apparatus and method for hadron beam verification. The apparatus allows to verify a number of different characteristics in a brief time span. The apparatus comprises at least one main degrader element and associated therewith a multiple thickness degrader element. The latter may comprise a number of patches of beam degrading material, the patches having constant but mutually different thicknesses. Alternatively, it may be a wedge-shaped element. By aiming a pencil beam at the various thicknesses, data points can be obtained which allow to make an estimation of the beam range. In addition to this, the apparatus comprises a zone where no degrader material is present, and where a measurement of the spot size can be obtained, without moving or replacing the apparatus.
摘要翻译：本发明涉及一种用于强子束验证的装置和方法。该装置允许在短时间内验证许多不同的特征。该装置包括至少一个主降解元件并与其相关联的多个厚度降级元件。后者可以包括许多光束退化材料的斑块，所述贴片具有恒定但相互不同的厚度。或者，它可以是楔形元件。通过瞄准各种厚度的笔形光束，可以获得允许估计光束范围的数据点。除此之外，该装置还包括不存在降解材料的区域，并且可以在不移动或更换设备的情况下获得斑点尺寸的测量。

3. 发明公开

EP3815742A1 RADIOTHERAPY APPARATUS COMPRISING AN IMAGING RING 审中-公开
公开(公告)号：EP3815742A1
公开(公告)日：2021-05-05
申请号：EP19206319.6
申请日：2019-10-30
申请人： Ion Beam Applications S.A.
发明人： DEBATTY, Alexandre , DESSY, Frédéric , CLAEREBOUDT, Yves
IPC分类号： A61N5/10 , A61B6/00
摘要： Radiotherapy apparatus for the delivery of an energetic beam to a target tissue in a treatment zone of said radiotherapy system, wherein
a) the radiotherapy apparatus comprises a rotatable gantry (1) for rotating the end (2) of a beam delivery system about a circle centered on an isocentre I and normal to an axis of rotation Z1 of the gantry (1), the path between the end (2) of the beam delivery system and the isocentre I defining a central beam axis Z2 at every rotation angle of the gantry (1) about the axis of rotation Z1 ;
b) the radiotherapy apparatus comprises an imaging ring (3), said imaging ring (3) comprising a central bore (4), said imaging ring (3) comprising an imaging system for acquiring images of a patient in an imaging zone of said imaging system,
c) the imaging ring (3) is located in the radiotherapy apparatus such that its imaging zone intersects the axis of rotation Z1 of the gantry, and the imaging ring (3) is mechanically coupled to the rotatable gantry (1) through a mechanical structure (6).

4. 发明授权

EP3285869B1 PHANTOM AND METHOD FOR QUALITY ASSURANCE OF A PARTICLE THERAPY APPARATUS 有权转让
公开(公告)号：EP3285869B1
公开(公告)日：2019-06-12
申请号：EP16718336.7
申请日：2016-04-22
申请人： Ion Beam Applications S.A.
发明人： MARCELIS, Simon , CLAEREBOUDT, Yves , MERTENS, Thierry , DESSY, Frédéric
IPC分类号： A61N5/10 , A61B6/00

5. 发明公开

EP3305366A1 HADRON THERAPY APPARATUS FOR ADAPTIVE TREATMENT IN NON-SUPINE POSITION 审中-公开
标题翻译： HADRON治疗仪适用于非超级位置的自适应治疗
公开(公告)号：EP3305366A1
公开(公告)日：2018-04-11
申请号：EP16192770.2
申请日：2016-10-07
申请人： ION BEAM APPLICATIONS S.A.
发明人： FORTON, Eric , BERTRAND, Damien , CLAEREBOUDT, Yves , VAN DER KRAAIJ, Erik
IPC分类号： A61N5/10
CPC分类号： A61N5/1069 , A61B6/03 , A61B6/0421 , A61N5/103 , A61N5/1037 , A61N5/1038 , A61N5/1049 , A61N5/1077 , A61N2005/1055 , A61N2005/1087
摘要： The invention relates to an apparatus comprising a hadron therapy device and a magnetic resonance imaging device (MRI). The MRI is an open MRI, for acquiring magnetic resonance data in the MRI imaging volume. The nozzle is fixed and positioned for directing a beam along a beam path substantially along said axis, or substantially perpendicularly to said axis. The apparatus comprises a patient support system adapted for supporting a patient in a non-supine position in said MRI. The invention also relates to methods for adapting a treatment plan to movements of organs resulting from displacement of a patient from a supine position wherein treatment plan imaging was performed to a non-supine position for performing the treatment.
摘要翻译：本发明涉及包含强子治疗装置和磁共振成像装置（MRI）的装置。 MRI是一种开放的MRI，用于采集MRI成像体积中的磁共振数据。喷嘴被固定和定位，用于沿着光束路径基本上沿所述轴线或基本上垂直于所述轴线引导光束。该装置包括适于在所述MRI中以非仰卧位置支撑患者的患者支撑系统。本发明还涉及用于使治疗计划适应由于患者从仰卧位置移位引起的器官移动的方法，其中执行治疗计划成像到非仰卧位置以进行治疗。

6. 发明公开

EP2043743A1 METHOD FOR TREATING A TARGET VOLUME WITH A PARTICLE BEAM AND DEVICE IMPLEMENTING SAME 审中-公开
标题翻译：法处理的目标体积有用于实现该方法的颗粒和装置
公开(公告)号：EP2043743A1
公开(公告)日：2009-04-08
申请号：EP07726615.3
申请日：2007-03-02
申请人： ION BEAM APPLICATIONS S.A.
发明人： CLAEREBOUDT, Yves
IPC分类号： A61N5/10 , G21K5/04
CPC分类号： A61N5/10 , A61N5/1043 , A61N5/1044 , A61N5/1048 , A61N2005/1087 , G21K5/04
摘要： A method for treating or irradiating a target volume (10) with a charged particle beam (100), to the target volume being associated three coordinates according to a X, Y and Z direction, the Z coordinate corresponding to the beam direction while the X and Y coordinates correspond to directions perpendicular to the Z direction, said charged particle beam producing in said target volume an irradiation spot (101), the method comprising the following steps: - continuously scanning said spot in the X and Y directions and applying a continuous movement to said spot in the Z direction by seamlessly modifying the energy of said beam, the step of applying a continuous movement in Z direction and the step of continuous scanning in X and Y direction being performed simultaneously, thereby performing a continuous 3D scanning of the target volume.

7. 发明授权

EP3307031B1 METHOD AND SYSTEM FOR CONTROLLING ION BEAM PULSES EXTRACTION 有权
公开(公告)号：EP3307031B1
公开(公告)日：2019-04-17
申请号：EP16192454.3
申请日：2016-10-05
申请人： Ion Beam Applications S.A.
发明人： KRIER, Gabriel , HENROTIN, Sébastien , CLAEREBOUDT, Yves
IPC分类号： H05H7/00 , H05H13/02

8. 发明公开

EP3307031A1 METHOD AND SYSTEM FOR CONTROLLING ION BEAM PULSES EXTRACTION 有权
标题翻译：控制离子束脉冲提取的方法和系统
公开(公告)号：EP3307031A1
公开(公告)日：2018-04-11
申请号：EP16192454.3
申请日：2016-10-05
申请人： Ion Beam Applications S.A.
发明人： KRIER, Gabriel , HENROTIN, Sébastien , CLAEREBOUDT, Yves
IPC分类号： H05H7/00 , H05H13/02
CPC分类号： H05H13/02 , A61N5/1043 , A61N2005/1087 , H05H7/001 , H05H7/02 , H05H7/04 , H05H2007/008 , H05H2007/022 , H05H2007/025 , H05H2007/046 , H05H2277/10
摘要： A first aspect of present invention is related to a method for controlling the extraction of ion beam pulses produced by a synchrocyclotron according to an irradiation plan. The synchrocyclotron comprises electrodes configured to be placed in a magnetic field, wherein an alternating voltage is applied between the electrodes, and wherein the frequency of the alternating voltage is modulated in a cyclic manner. The method comprises the steps of starting an acceleration cycle of the synchrocyclotron (12), generating a reference signal (38) when the modulated frequency reaches a predefined value (42), communicating the time, at which the reference signal (38) is generated, to the one or more beam control elements (20, 22), assessing one or more status parameters of the one or more beam control elements (20, 22), wherein the assessment is synchronised with the generation of the reference signal (38), cancelling or proceeding with the extraction of the beam pulse depending on the results of the assessment. A second aspect of the present invention is related to an ion beam extraction system configured to perform the method according to the first aspect of the present invention.
摘要翻译：本发明的第一方面涉及一种用于根据照射计划来控制由同步回旋加速器产生的离子束脉冲的提取的方法。同步回旋加速器包括被配置为放置在磁场中的电极，其中交流电压被施加在电极之间，并且其中交流电压的频率以循环的方式被调制。该方法包括步骤：启动同步回旋加速器（12）的加速周期，当调制频率达到预定值（42）时产生参考信号（38），传送参考信号（38）产生的时间向所述一个或多个射束控制元件（20,22）发送所述一个或多个射束控制元件（20,22）的一个或多个状态参数，其中所述评估与所述参考信号（38）的生成同步，，根据评估结果取消或继续提取光束脉冲。本发明的第二方面涉及配置成执行根据本发明的第一方面的方法的离子束提取系统。

9. 发明公开

EP2040800A2 METHOD AND SOFTWARE FOR IRRADIATING A TARGET VOLUME WITH A PARTICLE BEAM AND DEVICE IMPLEMENTING SAME 审中-公开
标题翻译：方法和软件，用于与设备的目标照射VOLUME执行本粒子束的
公开(公告)号：EP2040800A2
公开(公告)日：2009-04-01
申请号：EP07726613.8
申请日：2007-03-02
申请人： ION BEAM APPLICATIONS S.A.
发明人： CLAEREBOUDT, Yves , DEMARET, Denis , DE LE HOYE, Jean-François
IPC分类号： A61N5/10 , H01J37/302 , H01J37/147
CPC分类号： G21K5/00 , A61N5/10 , A61N5/103 , A61N5/1043 , A61N2005/1087 , G21K1/08
摘要： The present invention is related to a method for treating or irradiating a target volume with a particle beam produced by an accelerator, comprising the steps of : deflecting said particle beam with the help of scanning means in two orthogonal (X, Y) directions, thereby constituting an irradiation plane perpendicular to the direction (Z) of the beam, defining in the irradiation plane a scanning field (Sx, Sy) which circumscribes the area of intersection of target volume and irradiation plane and scanning said scanning field by drawing scan lines which form a scan pattern comprising interleaved frames of triangle waves. The scan pattern is preferably continuous and represents contiguous rhombi figures. The invention is equally related to a device and a software program implementing the method.

10. 发明授权

EP3035777B1 ROTATING ENERGY DEGRADER 有权
标题翻译： ROTIERENDER ENERGIEABSTUFER
公开(公告)号：EP3035777B1
公开(公告)日：2017-02-08
申请号：EP15197444.1
申请日：2015-12-02
申请人： ION BEAM APPLICATIONS S.A.
发明人： CLAEREBOUDT, Yves , DEBATTY, Alexandre , GERARD, Nicolas
IPC分类号： H05H7/12 , A61N5/00 , G21K1/00
CPC分类号： G21K1/00 , A61N5/1077 , A61N2005/1087 , A61N2005/1095 , G21K1/10 , H05H7/12 , H05H2007/125 , H05H2277/11

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