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    • 1. 发明公开
    • A microencapsulated amino acid composition and method of manufacturing microencapsulated amino acid composition
    • 微胶囊化的氨基酸组成含及其制造方法的微囊化氨基酸组成
    • EP2719290A1
    • 2014-04-16
    • EP13188328.2
    • 2013-10-11
    • Innobio Limited
    • Wu, WenzhongChen, JianbinZhang, Yuemei
    • A23L1/305A23L1/30A23L1/00A61K9/20A61K9/28C08J3/12A61K31/195A61K31/198A61K31/401A61K31/405A61K31/4172B01J13/22A23L1/22A61K38/00
    • A61K9/1605A23L33/175A23P10/30A23P30/20A23V2002/00A61K9/0095A61K9/1617A61K9/1652A61K9/1682A61K31/198A23V2200/224A23V2250/0626A23V2250/0628A23V2250/0654A23V2250/51082A23V2250/51086A23V2250/5028A61K2300/00
    • The invention relates to a microencapsulated amino acid composition and methods of manufacturing this composition. Amino acids, such as branched-chain amino acids, have low water solubility, poor hydrophilicity, and poor stability. Amino acids are thus difficult to be digested and absorbed. Consequently amino acids can hardly meet human needs of consuming. This microencapsulated amino acid composition that can quickly disperse and dissolve in cold water, resulting clear solution. The method includes (1) adding coating agents, wetting agents, or other excipients to the amino acid mixture, (2) modifying the surface of microencapsulated particles to considerably accelerate the wetting speed. In this composition, the weight ratio of amino acids and excipients is from 100/0.1 to 100/10.0. This invention delivers advantages over conventional products, such as instant dispersion and dissolution in water, transparent solution, no precipitation, no floating, no foam, increased shelf life, more convenient, and faster oral absorption. Therefore, the present invention is a good solution to the problems of amino acids, resolving the problems related to prior products. The present invention does not have unpleasant taste or odor that prior amino acids bring to consumers. The method of the present invention is simple and easy to be industrialized.
    • 本发明涉及微胶囊化的氨基酸组成和制造该组合物的方法。 氨基酸,:作为支链氨基酸,例如,具有低的水溶性,亲水性差,稳定性差。 氨基酸因此难以被消化吸收。 因此氨基酸难以满足消费的人的需求。 这种微囊包封的氨基酸组合物也可以快速分散并溶解在冷水中,得到的澄清溶液。 该方法包括:(1)将包衣剂,润湿剂,或其它赋形剂的氨基酸混合物,(2)微胶囊化的改性粒子的表面显着地加快润湿速度。 在这种组合物中,氨基酸和赋形剂的重量比为100 / 0.1〜100 / 10.0。 本发明提供超过常规产品,:如在水中瞬间分散和溶解,透明的溶液,无沉淀,无浮,无泡沫,增加的货架寿命,更方便,和更快的口服吸收的优点。 因此,本发明是一种很好的解决了氨基酸的问题,解决与现有产品的问题。 本发明没有难闻的味道或气味没有事先氨基酸带给消费者。 本发明的方法是简单和容易实现工业化。