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    • 2. 发明公开
    • FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1,2,3-TRIAZOLES VIA 1,3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF
    • 作者的1,2,3-三唑的1,3-偶极环加成及其聚合物官能化4和5-乙烯基取代的区域异构体
    • EP2405757A1
    • 2012-01-18
    • EP10751274.1
    • 2010-03-09
    • Isp Investments Inc.
    • MUSA, Osama M.MARR, Brian
    • A01N43/64
    • C07D249/04A01N43/647A61K8/496A61K8/817A61K2800/10A61Q19/00C07D295/155C08F26/06C09D139/04C09J139/04C11D3/28C11D3/3776A01N25/10
    • The present invention provides novel functionalized mixtures 4- and 5-vιnyl substituted regioisomers of 1,2,3-triazoles via 1,3-dιpolar cycloaddition. Functionalized alkyne moieties with a terminal alcoholic functionality are reacted with functionalized organic moieties with a terminal leaving group and an azide to provide an alcoholic functionalized mixture of 4- and 5-substιtuted regioisomers of 1,2,3- triazole moieties. The mixture may be converted to a wide variety of useful functionalized mixtures of 4- and 5-vιnyl substituted regioisomers of 1,2,3-triazole moieties, which in turn can be converted to a wide variety of useful polymers The novel alcoholic functionalized mixtures of 4- and 5-substιtuted regioisomers can be separated by chromatography to provide the purified 4- and 5- alcoholic functionalized substituted 1,2,3-trιazole moieties. The novel compounds of the invention can be employed in a wide variety of compositions (Formulae (I), (II)); wherein R
      1 , R
      2 , R
      3 , and R
      4 , are defined herein.
    • 本发明通过环加成1,3-偶极提供了新颖的官能混合物4-和1,2,3-三唑-5-乙烯基substituiertem区域异构体。 对与具有终端的离去基团的官能化有机基团进行反应,并在酸性末端醇官能化功能炔部分以提供的1,2,3-三唑基部分4-和5- substituiertem区域异构体醇官能混合物。 该混合物可以被转换为各种各样的的1,2,3-三唑基部分4-和5-乙烯基substituiertem区域异构体,其又可以被转换为各种各样的有用的聚合物的新的官能化醇混合物的官能化有用混合物 4-和5- substituiertem的区域异构体可以通过色谱法分离以提供纯化的4-和5-醇官能substituiertem 1,2,3-三唑基部分。 本发明的新化合物可以在各种组合物中采用(式(I),(II)); worin R1,R2,R3和R4,在被定义。
    • 4. 发明公开
    • VINYL LACTAM-DERIVED POLYMERS, COMPOSITIONS THEREOF HAVING ENHANCED WATER-RESISTANCE, AND METHODS OF USE THEREOF
    • 乙烯基内酰胺衍生的聚合物,其组合物具有改进的耐水性及其方法使用
    • EP3126417A1
    • 2017-02-08
    • EP15774060.6
    • 2015-03-30
    • ISP Investments Inc.
    • TALLON, Michael A.GHOSH, MousumiNACHARAJU, KrishnamurthyFARES, Hani M.PRETTYPAUL, Donald I.MUSA, Osama M.
    • C08F226/06
    • C08F226/06A61K8/817A61K47/34A61Q17/04C08F220/18C08F226/08C08F226/10C08F2220/1858C08F220/14
    • The invention provides polymers comprising repeating units derived from (a) from 16 % by weight to about 35 % by weight of said polymer of at least one N- vinyl lactam monomer; (b) at least one monomer selected from the group consisting of functionalized and unfunctionalized C1-C6 alkyl (meth)acrylates, C1-C6 alkyl (meth)acrylamides and combinations thereof; and (c) at least one monomer selected from the group consisting of functionalized and unfunctionalized C8-C30 branched alkyl (meth)acrylates, C8-C30 branched alkyl (meth)acrylamides, and combinations thereof; wherein the polymer has a glass transition temperature of greater than about 45°C. The invention further provides various compositions, such as, personal care, sun care, coatings, and pharmaceutical compositions comprising the polymers described herein. The invention furthermore provides water-resistant sun care compositions comprising the polymers described herein. Subscripts x, y and z are described herein. (Formula (I))
    • 本发明提供聚合物,其包含以重量计的至少一种N-乙烯基内酰胺单体的所述聚合物的来自(a)由16重量%至约35%的重复单元; (B)选自官能化和未官能化的C1-C6烷基(甲基)丙烯酸酯,C1-C6烷基(甲基)丙烯酰胺以及它们的组合中选择的至少一种单体; 和(c)选自下组的官能化和未官能化的C8-C30的中的至少一种单体支链烷基(甲基)丙烯酸酯,C8-C30支链烷基(甲基)丙烯酰胺,以及它们的组合; worin所述聚合物具有大于约45℃的玻璃化转变温度 本发明还提供各种组合物,:诸如,个人护理,防晒护理,涂料,和药物组合物包括在所描述的聚合物。 本发明进一步提供更耐水的防晒组合物,包含在所描述的聚合物。 标x,y和z被描述英寸 (式(I))