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    • 9. 发明授权
    • STREPTOCOCCUS PYOGENES ANTIGENS AND CORRESPONDING DNA FRAGMENTS
    • 抗原基因突变体原核生物
    • EP1343895B1
    • 2008-06-18
    • EP01271387.1
    • 2001-12-21
    • ID Biomedical Corporation
    • MARTIN, DenisBRODEUR, Bernard,R.HAMEL, JoséeRIOUX, StéphaneRHEAULT, Patrick
    • C12N15/31C07K14/315C12N15/63C07K19/00A61K39/09G01N33/569
    • C07K14/315A61K38/00A61K39/00A61K39/0208A61K39/092A61K2039/575C07K2319/00G01N33/56944G01N2333/315G01N2469/20
    • The present invention relates to antigens, more particularly antigens of Streptococcus pyogenes (also called group A Streptococcus (GAS)) bacterial pathogen which are useful as vaccine component for therapy and/or prophylaxis.
    • 本发明涉及用作治疗和/或预防的疫苗组分的抗原,更特别是化脓性链球菌(也称为A链球菌(GAS))细菌病原体的抗原。
      1 ATGAAAAAGA CATTAACTTT GCTACTGGCA CTCTTTGCCA 61 AGAGCGGAGG ATGAACAAAG TAGTACACAA AAGCCAGTAA AATTTGATTT GGATGGACCT / row> 121 CAACAAAAAA TTAAAGATTA TAGTGGCAAC ACAATCACTC TAGAAGACTT ATATGTTGGT 行> 181 AGTAAAGTAG TAAAAATATA TATCCCTCAA GGATGGTGGG TATATCTTTA C AGACAATGT 241 GATCATAACA GTAAAGAACG AGGAATTTTA GCTAGTCCTA 行> TTCTCGAAAA AAATATAACA 301 AAAACAGATC CTTATCGTCA ATATTATACA GGAGTACCTT ATATTCTTAA CTTAGGAGAA 361 GATCCTTTGA AGAAAGGAGA AAAATTAACT TTCTCATTTA AAGGAGAAGA CGGATTTTAT / row> 421 GTCGGTAGCT ATATCTATAG AGACTCTGAT ACTATAAAAA AAGAAAAAGA AGCTGAAGAA 行> 481 GCACTTCAAA AAAAGGAAGA GGAAAAGCAA CAAAAACAGC TAGAAGAAAG CATGCTAAAG 541 CAGATAAGAG AA GAAGACCA TAAACCTTGG CATCAGCGGT TAAGTGAGAG CATCCAAGAT 601 CAGTGGTGGA ACTTTAAGGG AQTGTTTCAG TGA