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1. 发明公开

EP3023072A1 Laser system and method for controlling the laser pulse shape 有权
标题翻译：激光系统zur Steuerung der Laserimpulsform
公开(公告)号：EP3023072A1
公开(公告)日：2016-05-25
申请号：EP14194451.2
申请日：2014-11-24
申请人： Fotona d.o.o.
发明人： Marincek, Marko , Nendl, Janko , Mocnik, Matjaz , Lukac, Matjaz
IPC分类号： A61B18/20 , A61N5/06 , A61N5/067
CPC分类号： H01S3/0912 , A61B18/203 , A61B18/245 , A61B2017/00159 , A61B2018/00029 , A61B2018/00476 , A61B2018/00577 , A61B2503/40 , A61N2005/067
摘要： A laser system for medical treatment is disclosed which comprises a pump, wherein the laser system is adapted to be operated in pulsed operation so that at least one laser pulse of a temporally limited pulse duration (Tp) is generated. The generated laser pulse irradiates some part of the human or animal body so that a two-dimensional laser spot S is located on the top layer of the irradiated part of the human or animal body. The pump power of the pump of the laser system is modulated in such a way that the cumulative energy E s (T p / 2) which is delivered by said laser pulse to said laser spot S during the first half of the pulse duration is less than 45% of the energy E s (T p ) which is delivered by said laser pulse to said laser spot S during the entire pulse duration T p .
摘要翻译：公开了一种用于医疗的激光系统，其包括泵，其中激光系统适于在脉冲操作中操作，使得产生至少一个时间有限的脉冲持续时间（Tp）的激光脉冲。所产生的激光脉冲照射人体或动物体的一部分，使得二维激光光斑S位于人或动物身体的照射部分的顶层上。激光系统的泵的泵浦功率被调制成使得在脉冲持续时间的前一半期间由所述激光脉冲传送到所述激光点S的累积能量E s（T p / 2）较小超过在整个脉冲持续时间T p期间由所述激光脉冲传送到所述激光点S的能量E s（T p）的45％。

2. 发明公开

EP3023073A1 Laser system for tissue ablation 有权
标题翻译：激光系统zur Gewebeablation
公开(公告)号：EP3023073A1
公开(公告)日：2016-05-25
申请号：EP14194452.0
申请日：2014-11-24
申请人： Fotona d.o.o.
发明人： Marincek, Marko , Nendl, Janko , Matjaz, Mocnik , Matjaz, Lukac
IPC分类号： A61B18/20 , B23K26/06
CPC分类号： H01S3/11 , A61B18/20 , A61B2017/00159 , A61B2017/00185 , A61B2018/00029 , A61B2018/00577 , A61B2018/00642 , B23K26/0622 , B23K26/0626 , H01S3/092
摘要： A Laser system is disclosed which comprises a pump, wherein the laser system is adapted to be operated in pulsed operation so that at least one individual pulse of a temporally limited pulse duration (T o ) is generated, wherein the pulse ablates a material such that a debris cloud forms above the ablated material. Further, the pump power of the pump is modulated in such a way that the following three conditions are fulfilled:
(1) the intensity of the pulse oscillates between maximum values and minimum values during the pulse duration, wherein the laser pulse comprises a plurality of intensity maxima I max which occur at times {T i , i=1, ... N}; and a plurality of intensity minima I min which occur at times {t k , k=1, ... (N-1)}, wherein the intensity does not vanish at the intensity minima;
(2) the intensity oscillations of the laser pulse induce oscillations of the size of the debris cloud so that, during the pulse duration (T o ), there are at least two maxima of the size of the debris cloud which occur at times {τ j , j=1, ... M} and which are located in between two intensity maxima of the laser pulse; and
(3) at least 70 percent of the maxima of the size of the debris cloud occur near an intensity minimum of the pulse such that, for at least 70 percent of the maxima of the size of the debris cloud, the intensity of the pulse I(τ j ) at the time of the maximum of the size of the debris cloud is smaller than I min (t k ) + 0.5 x [I max (T i ) - I min (t k ) ], wherein I min (t k ) is the intensity minimum of the pulse which is closest to the maximum of the size of the debris cloud at time τ j and I max (T i ) is the intensity maximum of the pulse which is closest to the maximum of the size of the debris cloud at time τ j .
摘要翻译：公开了一种激光系统，其包括泵，其中激光系统适于在脉冲操作中操作，使得产生具有时间上有限的脉冲持续时间（T o）的至少一个单个脉冲，其中脉冲消融材料，使得在烧蚀材料之上形成碎屑云。此外，泵的泵浦功率被调制成满足以下三个条件：（1）脉冲强度在脉冲持续时间期间在最大值和最小值之间振荡，其中激光脉冲包括多个时间{T i，i = 1，... N}出现的强度最大值I max; 以及出现在时间{t k，k = 1，...（N-1）}}的多个强度最小值I min，其中强度不以强度最小值消失; （2）激光脉冲的强度振荡引起碎片云大小的振荡，使得在脉冲持续时间（T o）期间，有时存在碎片云大小的至少两个最大值（Ä j，j = 1，... M}，它们位于激光脉冲的两个强度最大值之间; 和（3）碎片云大小的最大值的至少70％出现在脉冲的强度最小值附近，使得对于碎片云大小的最大值的至少70％，脉冲的强度 I（Äj）在碎片云大小的最大值小于I min（tk）+ 0.5 x [I max（T i） - I min（tk）]时，其中I min（tk）是在时间Äj处最接近碎片云大小的最大值的脉冲的强度最小值，I max（T i）是最接近碎屑大小最大值的脉冲的强度最大值云在时间Äj。

3. 发明授权

EP3023072B1 Laser system for controlling the laser pulse shape 有权
标题翻译：用于控制激光脉冲形状的激光系统
公开(公告)号：EP3023072B1
公开(公告)日：2018-01-10
申请号：EP14194451.2
申请日：2014-11-24
申请人： Fotona d.o.o.
发明人： Marincek, Marko , Nendl, Janko , Mocnik, Matjaz , Lukac, Matjaz
IPC分类号： A61B18/20 , A61N5/06 , A61N5/067
CPC分类号： H01S3/0912 , A61B18/203 , A61B18/245 , A61B2017/00159 , A61B2018/00029 , A61B2018/00476 , A61B2018/00577 , A61B2503/40 , A61N5/06 , A61N2005/067
摘要： A laser system for medical treatment is disclosed which comprises a pump, wherein the laser system is adapted to be operated in pulsed operation so that at least one laser pulse of a temporally limited pulse duration (Tp) is generated. The generated laser pulse irradiates some part of the human or animal body so that a two-dimensional laser spot S is located on the top layer of the irradiated part of the human or animal body. The pump power of the pump of the laser system is modulated in such a way that the cumulative energy E s (T p / 2) which is delivered by said laser pulse to said laser spot S during the first half of the pulse duration is less than 45% of the energy E s (T p ) which is delivered by said laser pulse to said laser spot S during the entire pulse duration T p .

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