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    • 4. 发明公开
    • A CHITOSAN WOUND DRESSING AND ITS METHOD OF MANUFACTURING
    • CHISOSANWUNDVERBAND在VERFAHREN ZU SEINER HERSTELLUNG
    • EP2695622A1
    • 2014-02-12
    • EP12767681.5
    • 2012-01-17
    • Foshan United Medical Technologies Ltd
    • MO, XiaohuiWANG, XiaodongWU, Zhenjun
    • A61L15/28A61F13/02
    • A61L15/28A61L15/46A61L15/60A61L2300/404A61L2400/04B65B55/02C08L5/08
    • A wound dressing comprising acylated chitosan fibre. The dressing has a wet strength of 0.3 N/cm or above. The acylated chitosan fibre may have a degree of substitution of 0.10-0.50. The acylated chitosan fibre may preferably have a degree of substitution of 0.20-0.40. The dressing may have an absorbency of 5-25g/g of a solution containing 8.298g/l of sodium chloride and 0.368 g/l of calcium chloride dehydrate as measured by BSEN 13726-12002 Part 1 Aspects of Absorbency. The base material of the dressing may be chitosan fibre that has been chemically modified through an acylation process using anhydride and ethanol as the solvent. A method of manufacturing the wound dressing involves reacting chitosan fibre with anhydride and making acylated chitosan felt through a nonwoven process, and through cutting, packing and sterilizing processes.
    • 包含酰化壳聚糖纤维的伤口敷料。 敷料的湿强度为0.3N / cm以上。 酰化壳聚糖纤维可以具有0.10-0.50的取代度。 酰化壳聚糖纤维优选具有0.20-0.40的取代度。 敷料可以具有5-25g / g的含8.2-8g / l氯化钠和0.368g / l氯化钙脱水剂的溶液的吸光度,其通过BSEN 13726-12002 Part 1 Aspects of Absorbency测定。 敷料的基材可以是已经通过使用酸酐和乙醇作为溶剂的酰化方法化学改性的壳聚糖纤维。 制造伤口敷料的方法包括使壳聚糖纤维与酸酐反应,并通过非织造方法,通过切割,包装和灭菌方法制备酰化壳聚糖毡。