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    • 3. 发明公开
    • AQUEOUS DENTAL GLASS IONOMER COMPOSITION
    • 水性牙科玻璃离聚体组合物
    • EP3307229A1
    • 2018-04-18
    • EP16728697.0
    • 2016-06-13
    • Dentsply DeTrey GmbH
    • RENN, CarolineELSNER, OliverGANSEL, JuliaSCHEUFLER, ChristianWALZ, UweKLEE, JoachimMAIER, Maximilian
    • A61K6/083
    • A61K6/0835C08F220/18C08F220/60C08F226/02C08F2220/1825C08F2800/10C08F2810/50
    • The present invention relates to an aqueous dental glass ionomer composition comprising (A) a reactive particulate glass, (B) a water-soluble, polymerizable polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, whereby the polymerizable polymer has a polymer backbone and hydrolysis-stable pendant groups having one or more polymerizable carbon-carbon double bonds, wherein the polymerizable polymer is obtainable by a process comprising a) a step of copolymerizing a mixture comprising (i) a first copolymerizable monomer comprising at least one optionally protected carboxylic acid group and a first polymerizable organic moiety, and (ii) a second copolymerizable monomer comprising one or more optionally protected primary and/or secondary amino groups and a second polymerizable organic moiety, for obtaining an amino group containing copolymer; b) a step of coupling to the amino group containing copolymer a compound having a polymerizable moiety and a functional group reactive with an amino group of repeating units derived from the second copolymerizable monomer in the amino group containing copolymer obtained in the first step , wherein the optionally protected amino group is deprotected, so that polymerizable pendant groups are linked to the backbone by hydrolysis-stable linking groups, and, optionally, a step of deprotecting the protected carboxylic acid group after step a) or step b), for obtaining a polymerizable polymer; (C) a hydrolysis-stable, water-soluble monomer having one polymerizable double bond and optionally a carboxylic acid group, said monomer having a molecular weight of at most 200 Da; and (D) a polymerization initiator system.