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1. 发明授权

EP2110087B1 Tissue extraction and collection device 有权
标题翻译：组织提取和收集装置
公开(公告)号：EP2110087B1
公开(公告)日：2016-03-23
申请号：EP09250905.8
申请日：2009-03-27
申请人： DePuy Mitek, Inc.
发明人： Pesce, Robert S. , Cook, Shelby , Dimatteo, Kristian , Ranucci, Kevin , Boock, Robert
IPC分类号： A61B17/32 , A61B17/16 , A61B10/02 , A61B90/00
CPC分类号： A61B10/025 , A61B10/0096 , A61B10/0266 , A61B10/0283 , A61B17/1635 , A61B17/32002 , A61B2017/320064 , A61B2090/0807

2. 发明公开

EP2486878A3 Tissue extraction and collection device 有权转让
标题翻译：组织提取和收集装置
公开(公告)号：EP2486878A3
公开(公告)日：2013-10-30
申请号：EP12167165.5
申请日：2009-03-27
申请人： DePuy Mitek, Inc.
发明人： Pesce, Robert S. , Cook, Shelby , Dimatteo, Kristian , Ranucci, Kevin , Boock, Robert
IPC分类号： A61B17/32 , A61B17/16 , A61B10/02 , A61B10/00 , A61B19/00
摘要： Methods and device for extracting and collecting tissue, which can be used for example in tissue engineering and grafting applications, are disclosed. In one embodiment, a device can include an outer tube. A rotatable shaft can be disposed within the outer tube can have a tissue harvesting tip formed on its distal end, the tissue harvesting tip being effective to excise tissue upon rotation thereof. A tissue collection device can be included to receive and collected excised tissue, and the tissue collection device can indicate the amount of tissue collected therein. For example, the tissue collection device can include a straining element which collects excised tissue and an indicator by which to assess the amount of collected tissue. In some embodiments, the tissue collection device can translate to indicate the amount of collected tissue. In many cases, devices disclosed herein can include driving mechanisms that are adapted to drive a tissue harvesting tip such that the tip excises soft tissue, but stops when contacting bone (or soon after contacting bone). In some embodiments, the tissue harvesting tip can be effective to excise viable tissue samples, such that the samples can exhibit desirable proportions of viable cells. Further, in some embodiments, the tissue harvesting tips can excise a tissue sample with tissue particles falling in certain size ranges.
摘要翻译：公开了用于提取和收集组织的方法和设备，其可以用于例如组织工程和接枝应用中。在一个实施例中，装置可以包括外管。可以在外管内设置可旋转的轴，可以在其远端形成组织收获尖端，组织收获尖端在其旋转时有效切除组织。可以包括组织收集装置以接收和收集切除的组织，并且组织收集装置可以指示其中收集的组织的量。例如，组织收集装置可以包括收集切除组织的应变元件和用于评估收集组织量的指示器。在一些实施例中，组织收集装置可以平移以指示收集的组织的量。在许多情况下，本文公开的装置可以包括驱动机构，其适于驱动组织收获尖端，使得尖端切除软组织，但在接触骨时（或在接触骨之后不久）停止。在一些实施例中，组织收获尖端可以有效地切除活组织样本，使得样本可以展现期望比例的活细胞。此外，在一些实施例中，组织收集尖端可以切割组织样本，组织样本落在特定尺寸范围内。

3. 发明公开

EP2486878A2 Tissue extraction and collection device 有权转让
标题翻译： Gewebeextraktions-和Sammelvorrichtung
公开(公告)号：EP2486878A2
公开(公告)日：2012-08-15
申请号：EP12167165.5
申请日：2009-03-27
申请人： DePuy Mitek, Inc.
发明人： Pesce, Robert S. , Cook, Shelby , Dimatteo, Kristian , Ranucci, Kevin , Boock, Robert
IPC分类号： A61B17/32 , A61B17/16 , A61B10/02 , A61B10/00 , A61B19/00
摘要： Methods and device for extracting and collecting tissue, which can be used for example in tissue engineering and grafting applications, are disclosed. In one embodiment, a device can include an outer tube. A rotatable shaft can be disposed within the outer tube can have a tissue harvesting tip formed on its distal end, the tissue harvesting tip being effective to excise tissue upon rotation thereof. A tissue collection device can be included to receive and collected excised tissue, and the tissue collection device can indicate the amount of tissue collected therein. For example, the tissue collection device can include a straining element which collects excised tissue and an indicator by which to assess the amount of collected tissue. In some embodiments, the tissue collection device can translate to indicate the amount of collected tissue. In many cases, devices disclosed herein can include driving mechanisms that are adapted to drive a tissue harvesting tip such that the tip excises soft tissue, but stops when contacting bone (or soon after contacting bone). In some embodiments, the tissue harvesting tip can be effective to excise viable tissue samples, such that the samples can exhibit desirable proportions of viable cells. Further, in some embodiments, the tissue harvesting tips can excise a tissue sample with tissue particles falling in certain size ranges.
摘要翻译：公开了用于提取和收集组织的方法和装置，其可以用于组织工程和移植应用中。在一个实施例中，装置可以包括外管。可旋转的轴可以设置在外管内，可以在其远端上形成有组织收集尖端，组织收集尖端有效地在组织旋转时切除组织。可以包括组织收集装置以接收和收集切除的组织，并且组织收集装置可以指示其中收集的组织的量。例如，组织收集装置可以包括收集切除的组织的应变元件和用于评估收集的组织的量的指示器。在一些实施例中，组织收集装置可以平移以指示所收集的组织的量。在许多情况下，本文公开的装置可以包括适于驱动组织收集尖端的驱动机构，使得尖端切除软组织，但是当接触骨骼时（或者在接触骨骼之后不久）停止。在一些实施方案中，组织采集尖端可有效地切除活组织样品，使得样品可以表现出所需比例的活细胞。此外，在一些实施例中，组织采集尖端可以用落在一定尺寸范围内的组织颗粒来切除组织样本。

4. 发明公开

EP2294993A1 Tissue extraction and collection device 审中-公开
标题翻译： Gewebeextraktions-捕集装置
公开(公告)号：EP2294993A1
公开(公告)日：2011-03-16
申请号：EP10179808.0
申请日：2009-03-27
申请人： DePuy Mitek, Inc.
发明人： Pesce, Robert S. , Cook, Shelby , Dimatteo, Kristian , Ranucci, Kevin , Boock, Robert
IPC分类号： A61B17/32 , A61B17/16 , A61B10/02 , A61B10/00 , A61B19/00
CPC分类号： A61B10/025 , A61B10/0096 , A61B10/0266 , A61B10/0283 , A61B17/1635 , A61B17/32002 , A61B2017/320064 , A61B2090/0807
摘要： Device for extracting and collecting tissue, which can be used for example in tissue engineering and grafting applications, is disclosed. In one embodiment, a device can include an outer tube. A rotatable shaft can be disposed within the outer tube and can have a tissue harvesting tip formed on its distal end, the tissue harvesting tip being effective to excise tissue upon rotation thereof. A tissue collection device can be included to receive and collect excised tissue, and the tissue collection device can indicate the amount of tissue collected therein. In many cases, devices disclosed herein can include driving mechanisms that are adapted to drive a tissue harvesting tip such that the tip excises soft tissue, but stops when contacting bone (or soon after contacting bone). In some embodiments, the tissue harvesting tip can be effective to excise viable tissue samples, such that the samples can exhibit desirable proportions of viable cells. Further, in some embodiments, the tissue harvesting tips can excise a tissue sample with tissue particles falling in certain size ranges.

5. 发明公开

EP2294992A1 Tissue extraction and collection device 有权
标题翻译：组织提取和收集装置
公开(公告)号：EP2294992A1
公开(公告)日：2011-03-16
申请号：EP10179410.5
申请日：2009-03-27
申请人： DePuy Mitek, Inc.
发明人： Pesce, Robert S. , Cook, Shelby , Dimatteo, Kristian , Ranucci, Kevin , Boock, Robert
IPC分类号： A61B17/32 , A61B17/16 , A61B10/02 , A61B10/00 , A61B19/00
CPC分类号： A61B10/025 , A61B10/0096 , A61B10/0266 , A61B10/0283 , A61B17/1635 , A61B17/32002 , A61B2017/320064 , A61B2090/0807
摘要： Device for extracting and collecting tissue, which can be used for example in tissue engineering and grafting applications, is disclosed. In one embodiment, a device can include an outer tube. A rotatable shaft can be disposed within the outer tube and can have a tissue harvesting tip formed on its distal end, the tissue harvesting tip being effective to excise tissue upon rotation thereof. A tissue collection device can be included to receive and collect excised tissue, and the tissue collection device can indicate the amount of tissue collected therein. In many cases, devices disclosed herein can include driving mechanisms that are adapted to drive a tissue harvesting tip such that the tip excises soft tissue, but stops when contacting bone (or soon after contacting bone). In some embodiments, the tissue harvesting tip can be effective to excise viable tissue samples, such that the samples can exhibit desirable proportions of viable cells. Further, in some embodiments, the tissue harvesting tips can excise a tissue sample with tissue particles falling in certain size ranges.
摘要翻译：披露了用于提取和收集组织的装置，其可用于例如组织工程和移植应用中。在一个实施例中，装置可以包括外管。可旋转的轴可以布置在外管内并且可以具有形成在其远端上的组织收集尖端，组织收获尖端在其旋转时有效地切除组织。可以包括组织收集装置以接收和收集切除的组织，并且组织收集装置可以指示其中收集的组织的量。在许多情况下，本文公开的装置可以包括驱动机构，其适于驱动组织收获尖端，使得尖端切除软组织，但在接触骨时（或在接触骨之后不久）停止。在一些实施例中，组织收获尖端可以有效地切除活组织样本，使得样本可以展现期望比例的活细胞。此外，在一些实施例中，组织收集尖端可以切割组织样本，组织样本落在特定尺寸范围内。

6. 发明公开

EP2110087A1 Tissue extraction and collection device 有权
标题翻译：组织提取和收集装置
公开(公告)号：EP2110087A1
公开(公告)日：2009-10-21
申请号：EP09250905.8
申请日：2009-03-27
申请人： DePuy Mitek, Inc.
发明人： Pesce, Robert S. , Cook, Shelby , Dimatteo, Kristian , Ranucci, Kevin , Boock, Robert
IPC分类号： A61B17/32 , A61B17/16 , A61B10/02 , A61B10/00 , A61B19/00
CPC分类号： A61B10/025 , A61B10/0096 , A61B10/0266 , A61B10/0283 , A61B17/1635 , A61B17/32002 , A61B2017/320064 , A61B2090/0807
摘要： Methods and device for extracting and collecting tissue, which can be used for example in tissue engineering and grafting applications, are disclosed. In one embodiment, a device (90) can include an outer tube (102). A rotatable shaft (110) can be disposed within the outer tube can have a tissue harvesting tip (106) formed on its distal end, the tissue harvesting tip being effective to excise tissue upon rotation thereof. A tissue collection device (128) can be included to receive and collected excised tissue, and the tissue collection device can indicate the amount of tissue collected therein. For example, the tissue collection device can include a straining element (1616) which collects excised tissue and an indicator by which to assess the amount of collected tissue. In some embodiments, the tissue collection device can translate to indicate the amount of collected tissue. In many cases, devices disclosed herein can include driving mechanisms (112) that are adapted to drive a tissue harvesting tip such that the tip excises soft tissue, but stops when contacting bone (or soon after contacting bone). In some embodiments, the tissue harvesting tip can be effective to excise viable tissue samples, such that the samples can exhibit desirable proportions of viable cells. Further, in some embodiments, the tissue harvesting tips can excise a tissue sample with tissue particles falling in certain size ranges.
摘要翻译：公开了用于提取和收集组织的方法和设备，其可以用于例如组织工程和接枝应用中。在一个实施例中，装置（90）可以包括外管（102）。可以在外管内设置可旋转的轴（110），其可以具有在其远端形成的组织收集尖端（106），组织收获尖端在其旋转时有效切除组织。可以包括组织收集装置（128）以接收和收集切除的组织，并且组织收集装置可以指示其中收集的组织的量。例如，组织收集装置可包括收集切除组织的应变元件（1616）和评估收集组织量的指示器。在一些实施例中，组织收集装置可以平移以指示收集的组织的量。在许多情况下，本文公开的装置可以包括适于驱动组织收获尖端的驱动机构（112），使得尖端切除软组织，但在接触骨时（或在接触骨之后不久）停止。在一些实施例中，组织收获尖端可以有效地切除活组织样本，使得样本可以展现期望比例的活细胞。此外，在一些实施例中，组织收集尖端可以切割组织样本，组织样本落在特定尺寸范围内。

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