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1. 发明公开

EP1346736A1 Intervertebral disk treatment using a crosslinking agent 有权
标题翻译： Bandenshebenbehandlung mit einem Vernetzer und einem Inaktivator oder Stabilisator
公开(公告)号：EP1346736A1
公开(公告)日：2003-09-24
申请号：EP03251687.4
申请日：2003-03-19
申请人： DePuy AcroMed, Inc.
发明人： Slivka, Michael Andrew , Serhan, Hassan
IPC分类号： A61L27/50
CPC分类号： A61L27/3612 , A61L27/24 , A61L27/3658 , A61L2430/38
摘要： Compositions for treating pathological intervertebral discs include an agent that causes chemical crosslinking of the native molecular components of the disc. Supplemental materials which are susceptible to crosslinking by the aforementioned agent are optionally delivered to the disc in order to increase and to maintain disc height.
摘要翻译：用于治疗病理性椎间盘的组合物包括引起盘的天然分子组分的化学交联的试剂。易于被上述试剂交联的补充材料可任选地输送到盘中以便增加并维持盘的高度。

2. 发明公开

EP1346694A2 Vertebral endplate milling device 审中-公开
标题翻译： FräsvorrichtungfürWIrbelendflächen
公开(公告)号：EP1346694A2
公开(公告)日：2003-09-24
申请号：EP03251688.2
申请日：2003-03-19
申请人： DePuy AcroMed, Inc.
发明人： Serhan, Hassan
IPC分类号： A61B17/16
CPC分类号： A61B17/1671 , A61B17/1617 , A61B17/1626 , A61B2017/1602 , A61B2090/061 , A61B2090/064
摘要： A device for preparing a space in the human spine to receive an insert between adjacent vertebral bodies includes a first abrading element (703) which has a first abrading surface (705) shaped to create a first predetermined surface contour in a vertebral body endplate, a first surface portion (707) facing away from the first abrading surface, and a second surface portion (709) facing away from the first abrading surface. The device includes a first distance adjustment element (711) having a first sliding surface (713) contacting the first inner surface portion for slidable engagement therewith, and a second distance adjustment element (715) having a second sliding surface (717) contacting the second inner surface portion for slidable engagement therewith. By moving the distance adjustment elements together or apart, the first abrading element may be moved to a position higher or lower on the sliding surface, when a variation in the height of the disk space must be accommodated, between the endplates which the abrading surface is intended to mill.
摘要翻译：一种用于在人类脊椎中准备空间以接纳相邻椎体之间的插入物的装置包括第一研磨元件（703），其具有第一研磨表面（705），所述第一研磨表面成形为在椎体终板中形成第一预定表面轮廓，第一表面部分（707），其背离第一研磨表面;以及第二表面部分（709），其背离第一研磨表面。该装置包括第一距离调节元件（711），该第一距离调节元件具有与第一内表面部分接触以便与其滑动接合的第一滑动表面（713）;以及第二距离调节元件（715），其具有与第二滑动表面内表面部分可与其滑动接合。通过将距离调整元件一起移动或分开，第一研磨元件可以在滑动表面上移动到更高或更低的位置，当必须容纳盘片空间的高度的变化时，研磨表面为打算磨。

3. 发明公开

EP1374789A3 Treatment of an intervertebral disc with an annulus fibrosus 审中-公开
标题翻译：椎间盘的环形修复
公开(公告)号：EP1374789A3
公开(公告)日：2004-05-19
申请号：EP03253922.3
申请日：2003-06-20
申请人： DePuy AcroMed, Inc.
发明人： Ryan, Thomas P. , Reynolds, Martin A. , Serhan, Hassan , Coston, Anthony
IPC分类号： A61B18/14
CPC分类号： A61B18/14 , A61B2018/0044 , A61B2018/1467 , A61B2018/1472
摘要： Apparatus for therapeutically treating an intervertebral disc having an annulus fibrosus with a fissure, comprising an instrument which provides first and second electrodes, which can be positioned adjacent the fissure, and a high frequncy RF energy device to generate a high frequency potential difference between the first and second electrodes. A hyper-conductive fluid can be provided between the electrodes.

4. 发明公开

EP1407730A1 Vertebral body distraction device 有权
标题翻译：椎体牵引装置
公开(公告)号：EP1407730A1
公开(公告)日：2004-04-14
申请号：EP03256344.7
申请日：2003-10-08
申请人： DePuy AcroMed, Inc.
发明人： Serhan, Hassan , Slivka, Michael
IPC分类号： A61F2/46 , A61B17/02
CPC分类号： A61F2/4455 , A61B17/00234 , A61B17/025 , A61B17/70 , A61B17/8805 , A61B2017/0256 , A61F2/441 , A61F2/442 , A61F2/4601 , A61F2/4611 , A61F2002/30583 , A61F2002/444 , A61F2002/4635 , A61F2210/0085
摘要： A device (10) for distracting two vertebral bodies and delivering a flowable material into the disc space, comprises a body (30) having a proximal portion (15) and a distal portion (32). The distal portion has a shape (17) adapted to distract the vertebral bodies. The body (30) has a longitudinal bore (37) defining a first outlet port (34) in the distal portion, and a first injection port (44) in the proximal portion (15).
摘要翻译：一种用于分散两个椎体并将可流动材料输送到椎间盘空间的装置（10）包括具有近侧部分（15）和远侧部分（32）的主体（30）。远侧部分具有适于分开椎体的形状（17）。本体（30）具有限定远端部分中的第一出口端口（34）的纵向孔（37）以及近端部分（15）中的第一注入端口（44）。

5. 发明公开

EP1346694A3 Vertebral endplate milling device 审中-公开
标题翻译：对于椎骨端铣削装置
公开(公告)号：EP1346694A3
公开(公告)日：2004-01-02
申请号：EP03251688.2
申请日：2003-03-19
申请人： DePuy AcroMed, Inc.
发明人： Serhan, Hassan
IPC分类号： A61B17/16 , A61B17/17
CPC分类号： A61B17/1671 , A61B17/1617 , A61B17/1626 , A61B2017/1602 , A61B2090/061 , A61B2090/064
摘要： A device for preparing a space in the human spine to receive an insert between adjacent vertebral bodies includes a first abrading element (703) which has a first abrading surface (705) shaped to create a first predetermined surface contour in a vertebral body endplate, a first surface portion (707) facing away from the first abrading surface, and a second surface portion (709) facing away from the first abrading surface. The device includes a first distance adjustment element (711) having a first sliding surface (713) contacting the first inner surface portion for slidable engagement therewith, and a second distance adjustment element (715) having a second sliding surface (717) contacting the second inner surface portion for slidable engagement therewith. By moving the distance adjustment elements together or apart, the first abrading element may be moved to a position higher or lower on the sliding surface, when a variation in the height of the disk space must be accommodated, between the endplates which the abrading surface is intended to mill.

6. 发明公开

EP1374789A2 Treatment of an intervertebral disc with an annulus fibrosus 审中-公开
标题翻译：椎间盘纤维环治疗
公开(公告)号：EP1374789A2
公开(公告)日：2004-01-02
申请号：EP03253922.3
申请日：2003-06-20
申请人： DePuy AcroMed, Inc.
发明人： Ryan, Thomas P. , Reynolds, Martin A. , Serhan, Hassan , Coston, Anthony
IPC分类号： A61B18/14
CPC分类号： A61B18/14 , A61B2018/0044 , A61B2018/1467 , A61B2018/1472
摘要： Apparatus for therapeutically treating an intervertebral disc having an annulus fibrosus with a fissure, comprising an instrument which provides first and second electrodes, which can be positioned adjacent the fissure, and a high frequncy RF energy device to generate a high frequency potential difference between the first and second electrodes. A hyper-conductive fluid can be provided between the electrodes.
摘要翻译：用于治疗性治疗具有裂隙的纤维环的椎间盘的设备，其包括提供可定位在裂缝附近的第一和第二电极以及高频RF能量设备以在第一和第二电极之间产生高频电势差的设备和第二电极。可以在电极之间提供超导电流体。

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