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1. 发明公开

EP4220188A1 MEASUREMENT SYSTEM, MEASUREMENT METHOD, INJECTOR, AND METHOD FOR INJECTING BIOMOLECULE-CONTAINING SOLUTION INTO-TO-BE INJECTED CELL USING SAME 审中-实审
公开(公告)号：EP4220188A1
公开(公告)日：2023-08-02
申请号：EP23167958.0
申请日：2019-07-25
申请人： Daicel Corporation
发明人： Kitaguchi, Toru , Miyazaki, Hiroshi , Sakaguchi, Yuko
IPC分类号： G01P5/26 , G01P13/00 , A61M5/30
摘要： The present invention relates to an injector configured to inject a solution containing biomolecules into an injection target and configured such that no injection is performed through a predetermined structure in a state, where the predetermined structure is inserted into the injection target, from an injector main body. The injector comprises: a storage unit in which a solution containing biomolecules is stored; and a nozzle part having an ejection port through which the pressurized solution containing biomolecules is able to flow and can be ejected into the injection target, wherein when a relationship between displacement x at a tip of the solution containing biomolecules in the injection target and velocity u(x) at the tip of the solution is fitted using a least squares method by a fitting function represented by Formula (1) below, a damping coefficient k is at least 1.59: u(x) = u 0 exp(-kx) + u e ... (1) (in Formula (1), u 0 represents a velocity coefficient (m/s), k represents a damping coefficient (1/mm), and u e represents an asymptotic velocity (m/s)).
Moreover, the present invention relates to an injector configured to inject a solution containing biomolecules into an injection target and configured such that no injection is performed through a predetermined structure in a state, where the predetermined structure is inserted into the injection target, from an injector main body. The injector comprises: a storage unit in which a solution containing biomolecules is stored; and a nozzle part having an ejection port through which the pressurized solution containing biomolecules is able to flow and can be ejected into the injection target, wherein when a relationship between displacement x at a tip of the solution containing biomolecules in the injection target and velocity u(x) at the tip of the solution is fitted using a least squares method by a fitting function represented by Formula (1) below, an asymptotic velocity u e is at least 0.01: u(x) = u 0 exp(-kx) + u e ... (1) (in Formula (1), u 0 represents a velocity coefficient (m/s), k represents a damping coefficient (1/mm), and u e represents an asymptotic velocity (m/s)).

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