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1. 发明公开

EP2841557A1 USE OF LACTIC ACID BACTERIA FOR PREPARING FERMENTED FOOD PRODUCTS WITH INCREASED NATURAL SWEETNESS 有权
标题翻译：乳酸菌用于制备发酵食品具有增加自然科学SWEET USE
公开(公告)号：EP2841557A1
公开(公告)日：2015-03-04
申请号：EP13719516.0
申请日：2013-04-25
申请人： Chr. Hansen A/S
发明人： JOHANSEN, Eric , SOERENSEN, Kim Ib , CURIC-BAWDEN, Mirjana , JUNGE, Mette Pia
IPC分类号： C12N1/20 , C12N9/12
摘要： The dairy industry today faces a problem of providing an alternative to adding sweeteners to fermented milk products in order to achieve the desired sweet taste without the added calories. Furthermore, it would be highly advantageous to establish a method for reducing lactose in fermented milk products to a level which is acceptable for lactose-intolerant consumers. The above problems have been solved by providing mutant Streptococcus thermophilus strains and mutant Lactobacillus delbrueckii subsp. bulgaricus strains that excrete glucose to the milk when the milk is inoculated and fermented with such Streptococcus thermophilus strains and Lactobacillus delbrueckii subsp, bulgaricus strains. Thus, the present invention relates to strains of Streptococcus thermophilus and Lactobacillus delbrueckii subsp, bulgaricus which secrete glucose to the milk substrate during fermentation, as well as to mixed cultures comprising the Streptococcus thermophilus strains and the Lactobacillus delbrueckii subsp, bulgaricus strains, starter cultures comprising the strains and dairy products manufactured with the cultures. The present method also relates to use of the strains for decreasing the lactose content of a fermented food product and for boosting growth of the probiotic BB-12®.
摘要翻译：乳制品行业今天所面临的提供对替代添加甜味剂发酵乳产品，以达到理想的甜味，而不会增加热量的问题。进一步，这将是高度有利的，建立一种用于在发酵乳制品减少乳糖为所有可接受的水平是乳糖不耐消费者。以上问题已经通过提供突变的嗜热链球菌菌株和突变体德氏乳杆菌解决。当牛奶接种，并与搜索嗜热链球菌和德氏乳杆菌杆菌保加利亚亚种菌株发酵菌种保加利亚没有排泄葡萄糖的牛奶。因此，本发明涉及嗜热链球菌和德氏乳杆菌亚种，保加利亚的菌株发酵期间分泌的葡萄糖的牛奶底物，以及以混合培养物，其包括嗜热链球菌菌株和德氏乳杆菌保加利亚亚种菌株，起始培养物，其包括菌株和乳制品与培养物生产。因此，本方法涉及使用菌株用于降低发酵食品中的乳糖含量和用于提升益生菌BB-12的生长。

2. 发明公开

EP0677110A1 RECOMBINANT LACTIC ACID BACTERIUM CONTAINING AN INSERTED PROMOTER AND METHOD OF CONSTRUCTING SAME 失效
标题翻译：插入的启动子含有重组乳酸菌
公开(公告)号：EP0677110A1
公开(公告)日：1995-10-18
申请号：EP94904150.0
申请日：1994-01-03
申请人： BIOTEKNOLOGISK INSTITUT , CHR. HANSEN A/S
发明人： ISRAELSEN, Hans , HANSEN, Egon Bech , JOHANSEN, Eric , MADSEN, Soren Michael , NILSSON, Dan , VRANG, Astrid
IPC分类号： A23C9 , A23K3 , A23L1 , A23L3 , A61K35 , C12N1 , C12N15 , C12Q1 , C12R1
CPC分类号： C12N15/746 , C12N15/1051 , C12N15/77 , C12N2800/90
摘要： A method of isolating a lactic acid bacterial DNA fragment comprising a promoter, the method comprising introducing a DNA molecule comprising a transposable element comprising a promoterless structural gene as a promoter probe gene into a population of a lactic acid bacterium, methods of constructing a recombinant lactic acid bacterium comprising a regulatable promoter by using the above method, a recombinant lactic acid bacterium comprising a gene coding for a desired gene product and operably linked thereto a regulatable lactic acid bacterial promoter not natively associated with the gene, the use of such a recombinant lactic acid bacterium and recombinant plasmids comprising a regulatable lactic acid bacterial promoter.

3. 发明授权

EP2630265B1 TEXTURIZING LACTIC ACID BACTERIA STRAINS 有权
标题翻译：增稠乳酸菌菌株
公开(公告)号：EP2630265B1
公开(公告)日：2017-03-22
申请号：EP11771202.6
申请日：2011-10-21
申请人： Chr. Hansen A/S
发明人： KIBENICH, Annette , SOERENSEN, Kim, Ib , JOHANSEN, Eric
IPC分类号： C12R1/225 , C12R1/46 , A23C9/127 , C12N9/90
CPC分类号： C12N1/20 , A23C9/1238 , A23Y2220/15 , A23Y2220/29 , A23Y2240/75 , C12N15/01 , C12N15/746 , C12R1/225 , C12R1/46

4. 发明授权

EP1073757B1 FOOD-GRADE CLONING VECTOR AND THEIR USE IN LACTIC ACID BACTERIA 有权
标题翻译：食品级克隆载体以及它们在乳酸菌使用
公开(公告)号：EP1073757B1
公开(公告)日：2012-11-28
申请号：EP99913119.6
申请日：1999-04-14
申请人： Chr. Hansen A/S
发明人： S RENSEN, Kim, Ib , LARSEN, Rasmus , JOHANSEN, Eric
IPC分类号： C12N15/74 , C12N15/68 , C12N9/88 , C12N9/48
CPC分类号： C12N15/68 , C12N15/746

5. 发明授权

EP0722503B1 LACTIC ACID BACTERIAL SUPPRESSOR MUTANTS AND THEIR USE AS SELECTIVE MARKERS AND AS MEANS OF CONTAINMENT IN LACTIC ACID BACTERIA 失效
标题翻译：乳酸细菌抑制突变体和它们作为选择性标记与乳酸菌的标准资源
公开(公告)号：EP0722503B1
公开(公告)日：2002-11-13
申请号：EP94929490.4
申请日：1994-10-07
申请人： CHR. HANSEN A/S
发明人： DICKELY, Françoise , JOHANSEN, Eric , NILSSON, Dan , HANSEN, Egon, Bech , STROEMAN, Per
IPC分类号： C12N15/74 , C12N15/68 , C12N1/21 , A23C3/08
CPC分类号： C12N15/68 , C12N15/746
摘要： Mutants of lactic acid bacteria or plasmids capable of replicating in lactic acid bacteria, comprising nonsense mutation suppressor-encoding genes, the use of such suppressor genes for confining a replicon to a specific lactic acid bacterium or to a lactic acid bacterium growing in a particular environment and for controlling the number of lactic acid bacterial cells in a particular environment.

6. 发明公开

EP2841573A1 AMPICILLIN RESISTANT TEXTURIZING LACTIC ACID BACTERIA STRAINS 无效
标题翻译： AMPICILLINRESSTETE TEXTURIERENDEMILCHSÄUREBAKTERIENSTÄMME
公开(公告)号：EP2841573A1
公开(公告)日：2015-03-04
申请号：EP13723011.6
申请日：2013-04-23
申请人： Chr. Hansen A/S
发明人： JOHANSEN, Eric , SOERENSEN, Kim Ib , KIBENICH, Annette
IPC分类号： C12N15/01 , A23C9/12 , C12N1/20 , C12R1/225
CPC分类号： A23C9/1238 , A23C2220/202 , A23Y2220/15 , A23Y2220/29 , A23Y2240/75 , C12N1/12 , C12N1/20 , C12N15/01 , C12R1/225
摘要： The present invention relates to mutants of lactic acid bacteria which are resistant to the antibiotic ampicillin and which were found to give an increased texture when grown in milk while maintaining the other growth properties of the parent strain. The present invention, furthermore, relates to compositions comprising such mutants, and to dairy products fermented with the lactic acid bacteria resistant to ampicillin.
摘要翻译：本发明涉及对抗生素氨苄青霉素具有抗性的乳酸菌突变体，并且在保持母体菌株的其它生长特性的同时，在牛奶中生长时，其质地增加。此外，本发明涉及包含这种突变体的组合物以及用氨苄青霉素耐药的乳酸菌发酵的乳制品。

7. 发明公开

EP2630265A1 TEXTURIZING LACTIC ACID BACTERIA STRAINS 有权
标题翻译： TEXTURIERENDEMILCHSÄUREBAKTERIENSTÄMME
公开(公告)号：EP2630265A1
公开(公告)日：2013-08-28
申请号：EP11771202.6
申请日：2011-10-21
申请人： Chr. Hansen A/S
发明人： KIBENICH, Annette , SOERENSEN, Kim, Ib , JOHANSEN, Eric
IPC分类号： C12R1/225 , C12R1/46 , A23C9/127 , C12N9/90
CPC分类号： C12N1/20 , A23C9/1238 , A23Y2220/15 , A23Y2220/29 , A23Y2240/75 , C12N15/01 , C12N15/746 , C12R1/225 , C12R1/46
摘要： The present invention relates to mutants of lactic acid bacteria which are resistant towards the antibiotic D-cycloserine and/or functionally equivalent antibiotics and which were found to give an increased texture when grown in milk while maintaining the other growth properties of the parent strain. The present invention, furthermore, relates to compositions comprising such mutants, and to dairy products fermented with the lactic acid bacteria resistant towards D-cycloserine and/or functionally equivalent antibiotics.
摘要翻译：本发明涉及对抗生素D-环丝氨酸和/或功能相当的抗生素具有抗性的乳酸菌的突变体，并且在保持母体菌株的其它生长特性的同时，在牛奶中生长时，其质地增加。此外，本发明涉及包含这种突变体的组合物，以及用对D-环丝氨酸和/或功能等同的抗生素具有抗性的乳酸菌发酵的乳制品。

8. 发明授权

EP2841573B1 AMPICILLIN RESISTANT TEXTURIZING LACTIC ACID BACTERIA STRAINS 无效
标题翻译： AMPICILLIN耐草酸乳酸菌菌株
公开(公告)号：EP2841573B1
公开(公告)日：2018-01-10
申请号：EP13723011.6
申请日：2013-04-23
申请人： Chr. Hansen A/S
发明人： JOHANSEN, Eric , SOERENSEN, Kim Ib , KIBENICH, Annette
IPC分类号： C12N15/01 , A23C9/12 , C12N1/20 , C12R1/225
CPC分类号： A23C9/1238 , A23C2220/202 , A23Y2220/15 , A23Y2220/29 , A23Y2240/75 , C12N1/12 , C12N1/20 , C12N15/01 , C12R1/225
摘要： The present invention relates to mutants of lactic acid bacteria which are resistant to the antibiotic ampicillin and which were found to give an increased texture when grown in milk while maintaining the other growth properties of the parent strain. The present invention, furthermore, relates to compositions comprising such mutants, and to dairy products fermented with the lactic acid bacteria resistant to ampicillin.

9. 发明公开

EP2721142A1 LACTOBACILLUS PLANTARUM CELLS WITH IMPROVED RESISTANCE TO HIGH CONCENTRATIONS OF ETHANOL 有权
标题翻译： LACTOBACILLUS PLANTARUM-ZELLEN MIT VERBESSERTER RESISTENZ GEGEN HOHE ETHANOLKONZENTRATIONEN
公开(公告)号：EP2721142A1
公开(公告)日：2014-04-23
申请号：EP12728479.2
申请日：2012-06-14
申请人： Chr. Hansen A/S
发明人： SOERENSEN, Kim Ib , KIBENICH, Annette , JOHANSEN, Eric
IPC分类号： C12N1/20 , C12N1/36
CPC分类号： C12G1/0203 , C12N1/20 , C12N1/36
摘要： Cycloserine resistant mutants of lactic acid bacteria characterized by having improved resistance towards ethanol. The cycloserine resistant mutants of lactic acid bacteria can e.g. be used for malolactic fermentations of wine (i.e. including sparkling wine such as Cava/champagne) having high alcohol levels.
摘要翻译：乳酸菌的环丝氨酸抗性突变体的特征在于对乙醇具有改善的抗性。乳酸菌的环丝氨酸抗性突变体可以例如。用于葡萄酒的乳酸发酵（即包括具有高酒精含量的起泡葡萄酒如卡瓦/香槟）。

10. 发明公开

EP1073757A1 FOOD-GRADE CLONING VECTOR AND THEIR USE IN LACTIC ACID BACTERIA 有权
标题翻译：食品级克隆载体以及它们在乳酸菌使用
公开(公告)号：EP1073757A1
公开(公告)日：2001-02-07
申请号：EP99913119.6
申请日：1999-04-14
申请人： Chr. Hansen A/S
发明人： S RENSEN, Kim, Ib , LARSEN, Rasmus , JOHANSEN, Eric
IPC分类号： C12N15/74 , C12N15/68 , C12N9/88 , C12N9/48
CPC分类号： C12N15/68 , C12N15/746
摘要： Novel food-grade cloning vectors comprising a nonsense mutation suppressor-encoding gene, which vector, when it is present in a lactic acid bacterial strain, permits such a strain to have an industrially appropriate growth rate and metabolic activity. The cloning vectors are useful when present in lactic acid bacteria used as starter cultures in the preparation of food or feed products, or a dairy flavour.

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